Oligogenic segregation analysis of hereditary prostate cancer pedigrees: Evidence for multiple loci affecting age at onset

International Journal of Cancer

Volumn 105, Issue 5, 2003, Pages 630-635

  Conlon, Erin M ^a,f   Goode, Ellen L ^c   Gibbs, Mark ^d   Stanford, Janet L ^d   Badzioch, Michael ^a   Janer, Marta ^e   Kolb, Suzanne ^d   Hood, Lee ^e   Ostrander, Elain A ^d   Jarvik, Gail P ^a,b   Wijsman, Ellen M ^a,b,g  

^a Division of Medical Genetics   (United States)

^b Department of Biostatistics ^*  (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d Fred Hutchinson Cancer Research Center   (United States)

^e INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^f HARVARD UNIVERSITY   (United States)

^g UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Ascertainment; Bayesian; Genetic heterogeneity; Markov chain Monte Carlo; Quantitative traits

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

ADULT; AGED; ARTICLE; BAYES THEOREM; BRAIN CANCER; CANCER SUSCEPTIBILITY; GENE MAPPING; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MALE GENITAL TRACT CANCER; MONTE CARLO METHOD; OLIGOGENIC SEGREGATION ANALYSIS; ONSET AGE; PEDIGREE ANALYSIS; PRIORITY JOURNAL; PROBABILITY; PROSTATE CANCER; PROSTATE DISEASE; QUANTITATIVE TRAIT; QUANTITATIVE TRAIT LOCUS; SEGREGATION ANALYSIS; STATISTICAL MODEL;

ADENOCARCINOMA; ADULT; AGE OF ONSET; AGED; ANTIGENS, NEOPLASM; BAYES THEOREM; BRAIN NEOPLASMS; CHROMOSOME SEGREGATION; COHORT STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MARKOV CHAINS; MIDDLE AGED; NEOPLASTIC SYNDROMES, HEREDITARY; NEUROECTODERMAL TUMORS, PRIMITIVE; PEDIGREE; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; QUANTITATIVE TRAIT LOCI; TUMOR MARKERS, BIOLOGICAL; UNITED STATES;

EID: 0037499554     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.11128     Document Type: Article

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