A population-based assessment of germline HOXB13 G84E mutation and prostate cancer risk

European Urology

Volumn 65, Issue 1, 2014, Pages 169-176

  Karlsson, Robert ^a   Aly, Markus ^a,b   Clements, Mark ^a   Zheng, Lilly ^c   Adolfsson, Jan ^a   Xu, Jianfeng ^c   Grönberg, Henrik ^a   Wiklund, Fredrik ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b DANDERYD HOSPITAL   (Sweden)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Genetic association study; HOXB13; Prostate cancer

Indexed keywords

HOMEOBOX B13 PROTEIN; HOMEODOMAIN PROTEIN; UNCLASSIFIED DRUG; HOXB13 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CANCER RISK; CONTROLLED STUDY; GENE MUTATION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PENETRANCE; POPULATION; POPULATION DYNAMICS; PREVALENCE; PRIORITY JOURNAL; PROSTATE BIOPSY; PROSTATE CANCER; SINGLE NUCLEOTIDE POLYMORPHISM; SWEDEN; CASE CONTROL STUDY; GENETICS; GERMLINE MUTATION; MIDDLE AGED; PROSTATIC NEOPLASMS; RISK ASSESSMENT;

ADULT; AGED; CASE-CONTROL STUDIES; GERM-LINE MUTATION; HOMEODOMAIN PROTEINS; HUMANS; MALE; MIDDLE AGED; PREVALENCE; PROSTATIC NEOPLASMS; RISK ASSESSMENT; SWEDEN;

EID: 84888839080     PISSN: 03022838     EISSN: 18737560     Source Type: Journal    
DOI: 10.1016/j.eururo.2012.07.027     Document Type: Article

References (27)

1. H. Grönberg Prostate cancer epidemiology Lancet 361 2003 859 864
2. C.L. Goh, F.R. Schumacher, and D. Easton Genetic variants associated with predisposition to prostate cancer and potential clinical implications J Intern Med 271 2012 353 365
3. M. Aly, F. Wiklund, and J. Xu Polygenic risk score improves prostate cancer risk prediction: results from the Stockholm-1 Cohort Study Eur Urol 60 2011 21 28
4. S.L. Zheng, J. Sun, and F. Wiklund Cumulative association of five genetic variants with prostate cancer N Engl J Med 358 2008 910 919
5. J. Sun, A.K. Kader, and F. Hsu Inherited genetic markers discovered to date are able to identify a significant number of men at considerably elevated risk for prostate cancer Prostate 71 2011 421 430
6. S. Lindström, F. Schumacher, and D.G. Cox Common genetic variants in prostate cancer risk prediction - results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3) Cancer Epidemiol Biomarkers Prev 21 2012 437 444
7. R.J. Klein, C. Hallden, and A. Gupta Evaluation of multiple risk-associated single nucleotide polymorphisms versus prostate-specific antigen at baseline to predict prostate cancer in unscreened men Eur Urol 61 2012 471 477
8. C.M. Ewing, A.M. Ray, and E.M. Lange Germline mutations in HOXB13 and prostate-cancer risk N Engl J Med 366 2012 141 149
9. J. Adolfsson, H. Garmo, and E. Varenhorst Clinical characteristics and primary treatment of prostate cancer in Sweden between 1996 and 2005 Scand J Urol Nephrol 41 2007 456 477
10. A. Heidenreich, J. Bellmunt, and M. Bolla EAU guidelines on prostate cancer. Part 1: Screening, diagnosis, and treatment of clinically localised disease Eur Urol 59 2011 61 71
11. NHLBI Exome Sequencing Project. US National Heart, Lung and Blood Institute Web site. http://evs.gs.washington.edu/EVS/. Accessed January 2012.
12. J.C. Barrett, B. Fry, J. Maller, and M.J. Daly Haploview: analysis and visualization of LD and haplotype maps Bioinformatics 21 2005 263 265
13. R Development Core Team. R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing; 2009.
14. K.J. Rothman, S. Greenland, and T.L. Lash Modern epidemiology ed. 3. 2008 Lippincott Williams & Wilkins Philadelphia, PA p. 430-1
15. P.D.P. Pharoah, A.C. Antoniou, D.F. Easton, and B.A.J. Ponder Polygenes, risk prediction, and targeted prevention of breast cancer N Engl J Med 358 2008 2796 2803
16. L.E. Johns, and R.S. Houlston A systematic review and meta-analysis of familial prostate cancer risk BJU Int 91 2003 789 794
17. S. Purcell, B. Neale, and K. Todd-Brown PLINK: a tool set for whole-genome association and population-based linkage analyses Am J Hum Genet 81 2007 559 575
18. D. Thompson, and D. Easton Variation in cancer risks, by mutation position, in BRCA2 mutation carriers Am J Hum Genet 68 2001 410 419
19. D. Thompson, and D.F. Easton Cancer incidence in BRCA1 mutation carriers J Natl Cancer Inst 94 2002 1358 1365
20. L. Tryggvadóttir, L. Vidarsdóttir, and T. Thorgeirsson Prostate cancer progression and survival in BRCA2 mutation carriers J Natl Cancer Inst 99 2007 929 935
21. H. Thorne, A.J. Willems, and E. Niedermayr Decreased prostate cancer-specific survival of men with BRCA2 mutations from multiple breast cancer families Cancer Prev Res 4 2011 1002 1010
22. The Breast Cancer Linkage Consortium Cancer risks in BRCA2 mutation carriers J Natl Cancer Inst 91 1999 1310 1316
23. Z. Kote-Jarai, D. Leongamornlert, and E. Saunders BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients Br J Cancer 105 2011 1230 1234
24. S. Sundararajan, A. Ahmed, and O.B. Goodman Jr. The relevance of BRCA genetics to prostate cancer pathogenesis and treatment Clin Adv Hematol Oncol 9 2011 748 755
25. D. Thompson, S. Seal, and M. Schutte A multicenter study of cancer incidence in CHEK2 1100delC mutation carriers Cancer Epidemiol Biomarkers Prev 15 2006 2542 2545
26. S. Pakkanen, T. Wahlfors, and S. Siltanen PALB2 variants in hereditary and unselected Finnish prostate cancer cases J Negat Results Biomed 8 2009 12
27. S.J. Hebbring, H. Fredriksson, and K.A. White Role of the Nijmegen breakage syndrome 1 gene in familial and sporadic prostate cancer Cancer Epidemiol Biomarkers Prev 15 2006 935 938