-
1
-
-
0018132578
-
Effects of cholestyramine and chenodeoxycholic acid on the metabolism of endogenous triglyceride in hyperlipoproteinemia
-
Angelin B, Einarsson K, Hellstrom K, Leijd B. Effects of cholestyramine and chenodeoxycholic acid on the metabolism of endogenous triglyceride in hyperlipoproteinemia. J Lipid Res 1978; 19: 1017-1024. (Pubitemid 9059813)
-
(1978)
Journal of Lipid Research
, vol.19
, Issue.8
, pp. 1017-1024
-
-
Angelin, B.1
Einarsson, K.2
Hellstrom, K.3
Leijd, B.4
-
3
-
-
85047694456
-
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c
-
DOI 10.1172/JCI200421025
-
Watanabe M, Houten SM, Wang L, Moschetta A, Mangelsdorf DJ, Heyman RA et al. Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c. J Clin Invest 2004; 113: 1408-1418. (Pubitemid 39071696)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.10
, pp. 1408-1418
-
-
Watanabe, M.1
Houten, S.M.2
Wang, L.3
Moschetta, A.4
Mangelsdorf, D.J.5
Heyman, R.A.6
Moore, D.D.7
Auwerx, J.8
-
4
-
-
0034791544
-
Farnesoid X-activated receptor induces apolipoprotein C-II transcription: A molecular mechanism linking plasma triglyceride levels to bile acids
-
DOI 10.1210/me.15.10.1720
-
Kast HR, Nguyen CM, Sinal CJ, Jones SA, Laffitte BA, Reue K et al. Farnesoid X-Activated receptor induces apolipoprotein C-II transcription: A molecular mechanism linking plasma triglyceride levels to bile acids. Mol Endocrinol 2001; 15: 1720-1728. (Pubitemid 32939302)
-
(2001)
Molecular Endocrinology
, vol.15
, Issue.10
, pp. 1720-1728
-
-
Kast, H.R.1
Nguyen, C.M.2
Sinal, C.J.3
Jones, S.A.4
Laffitte, B.A.5
Reue, K.6
Gonzalez, F.J.7
Willson, T.M.8
Edwards, P.A.9
-
5
-
-
0034664729
-
Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis
-
Sinal CJ, Tohkin M, Miyata M, Ward JM, Lambert G, Gonzalez FJ. Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell 2000; 102: 731-744.
-
(2000)
Cell
, vol.102
, pp. 731-744
-
-
Sinal, C.J.1
Tohkin, M.2
Miyata, M.3
Ward, J.M.4
Lambert, G.5
Gonzalez, F.J.6
-
6
-
-
14244264780
-
Regulation of carbohydrate metabolism by the farnesoid X receptor
-
DOI 10.1210/en.2004-0965
-
Stayrook KR, Bramlett KS, Savkur RS, Ficorilli J, Cook T, Christe ME et al. Regulation of carbohydrate metabolism by the farnesoid X receptor. Endocrinology 2005; 146: 984-991. (Pubitemid 40289284)
-
(2005)
Endocrinology
, vol.146
, Issue.3
, pp. 984-991
-
-
Stayrook, K.R.1
Bramlett, K.S.2
Savkur, R.S.3
Ficorilli, J.4
Cook, T.5
Christe, M.E.6
Michael, L.F.7
Burris, T.P.8
-
7
-
-
33645531297
-
The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice
-
DOI 10.1074/jbc.M510258200
-
Cariou B, Van Harmelen K, Duran-Sandoval D, Van Dijk TH, Grefhorst A, Abdelkarim M et al. The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice. J Biol Chem 2006; 281: 11039-11049. (Pubitemid 43855527)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.16
, pp. 11039-11049
-
-
Cariou, B.1
Van Harmelen, K.2
Duran-Sandoval, D.3
Van Dijk, T.H.4
Grefhorst, A.5
Abdelkarim, M.6
Caron, S.7
Torpier, G.8
Fruchart, J.-C.9
Gonzalez, F.J.10
Kuipers, F.11
Staels, B.12
-
8
-
-
22544452537
-
The farnesoid X receptor modulates hepatic carbohydrate metabolism during the fasting-refeeding transition
-
DOI 10.1074/jbc.M501931200
-
Duran-Sandoval D, Cariou B, Percevault F, Hennuyer N, Grefhorst A, Van Dijk TH et al. The farnesoid X receptor modulates hepatic carbohydrate metabolism during the fasting-refeeding transition. J Biol Chem 2005; 280: 29971-29979. (Pubitemid 41177076)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.33
, pp. 29971-29979
-
-
Duran-Sandoval, D.1
Cariou, B.2
Percevault, F.3
Hennuyer, N.4
Grefhorst, A.5
Van Dijk, T.H.6
Gonzalez, F.J.7
Fruchart, J.-C.8
Kuipers, F.9
Staels, B.10
-
9
-
-
78449258535
-
The farnesoid X receptor regulates adipocyte differentiation and function by promoting peroxisome proliferator-Activated receptor-gamma and interfering with the Wnt/ beta-catenin pathways
-
Abdelkarim M, Caron S, Duhem C, Prawitt J, Dumont J, Lucas A et al. The farnesoid X receptor regulates adipocyte differentiation and function by promoting peroxisome proliferator-Activated receptor-gamma and interfering with the Wnt/ beta-catenin pathways. J Biol Chem 2010; 285: 36759-36767.
-
(2010)
J Biol Chem
, vol.285
, pp. 36759-36767
-
-
Abdelkarim, M.1
Caron, S.2
Duhem, C.3
Prawitt, J.4
Dumont, J.5
Lucas, A.6
-
10
-
-
84865603263
-
Bile acid binding resin improves metabolic control through the induction of energy expenditure
-
Watanabe M, Morimoto K, Houten SM, Kaneko-Iwasaki N, Sugizaki T, Horai Y et al. Bile acid binding resin improves metabolic control through the induction of energy expenditure. PloS One 2012; 7: E38286.
-
(2012)
PloS One
, vol.7
-
-
Watanabe, M.1
Morimoto, K.2
Houten, S.M.3
Kaneko-Iwasaki, N.4
Sugizaki, T.5
Horai, Y.6
-
11
-
-
25144518617
-
Gallstones-Approach to medical management
-
Konikoff FM. Gallstones-Approach to medical management. MedGenMed 2003; 5: 8.
-
(2003)
MedGenMed
, vol.5
, pp. 8
-
-
Konikoff, F.M.1
-
12
-
-
79955890870
-
Bile acid metabolism and the pathogenesis of type 2 diabetes
-
Prawitt J, Caron S, Staels B. Bile acid metabolism and the pathogenesis of type 2 diabetes. Curr Diab Rep 2011; 11: 160-166.
-
(2011)
Curr Diab Rep
, vol.11
, pp. 160-166
-
-
Prawitt, J.1
Caron, S.2
Staels, B.3
-
13
-
-
37849022070
-
Syn thesis, characterization, and receptor interaction profiles of enantiomeric bile acids
-
Katona BW, Cummins CL, Ferguson AD, Li T, Schmidt DR, Mangelsdorf DJ et al. Synthesis, characterization, and receptor interaction profiles of enantiomeric bile acids. J Med Chem 2007; 50: 6048-6058.
-
(2007)
J Med Chem
, vol.50
, pp. 6048-6058
-
-
Katona, B.W.1
Cummins, C.L.2
Ferguson, A.D.3
Li, T.4
Schmidt, D.R.5
Mangelsdorf, D.J.6
-
14
-
-
84857625816
-
Farnesoid x receptor agonists: What they are and how they might be used in treating liver disease
-
Neuschwander-Tetri BA. Farnesoid x receptor agonists: What they are and how they might be used in treating liver disease. Curr Gastroenterol Rep 2012; 14: 55-62.
-
(2012)
Curr Gastroenterol Rep
, vol.14
, pp. 55-62
-
-
Neuschwander-Tetri, B.A.1
-
15
-
-
31444454037
-
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
-
DOI 10.1038/nature04330, PII NATURE04330
-
Watanabe M, Houten SM, Mataki C, Christoffolete MA, Kim BW, Sato H et al. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature 2006; 439: 484-489. (Pubitemid 43152840)
-
(2006)
Nature
, vol.439
, Issue.7075
, pp. 484-489
-
-
Watanabe, M.1
Houten, S.M.2
Mataki, C.3
Christoffolete, M.A.4
Kim, B.W.5
Sato, H.6
Messaddeq, N.7
Harney, J.W.8
Ezaki, O.9
Kodama, T.10
Schoonjans, K.11
Bianco, A.C.12
Auwerx, J.13
-
16
-
-
0347989317
-
Brown Adipose Tissue: Function and Physiological Significance
-
DOI 10.1152/physrev.00015.2003
-
Cannon B, Nedergaard J. Brown adipose tissue: Function and physiological significance. Physiol Rev 2004; 84: 277-359. (Pubitemid 38054374)
-
(2004)
Physiological Reviews
, vol.84
, Issue.1
, pp. 277-359
-
-
Cannon, B.1
Nedergaard, J.2
-
17
-
-
84873518501
-
Adaptive thermogenesis in adipocytes: Is beige the new brown?
-
Wu J, Cohen P, Spiegelman BM. Adaptive thermogenesis in adipocytes: Is beige the new brown? Genes Dev 2013; 27: 234-250.
-
(2013)
Genes Dev
, vol.27
, pp. 234-250
-
-
Wu, J.1
Cohen, P.2
Spiegelman, B.M.3
-
18
-
-
0018646453
-
A role for brown adipose tissue in diet-induced thermogenesis
-
DOI 10.1038/281031a0
-
Rothwell NJ, Stock MJ. A role for brown adipose tissue in diet-induced thermogenesis. Nature 1979; 281: 31-35. (Pubitemid 9247988)
-
(1979)
Nature
, vol.281
, Issue.5726
, pp. 31-35
-
-
Rothwell, N.J.1
Stock, M.J.2
-
19
-
-
79551501758
-
The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure
-
da-Silva WS, Ribich S, Arrojo e Drigo R, Castillo M, Patti ME, Bianco AC. The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure. FEBS Lett 2011; 585: 539-544.
-
(2011)
FEBS Lett
, vol.585
, pp. 539-544
-
-
Da-Silva, W.S.1
Ribich, S.2
Arrojoe Drigo, R.3
Castillo, M.4
Patti, M.E.5
Bianco, A.C.6
-
20
-
-
79960695556
-
Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure
-
Watanabe M, Horai Y, Houten SM, Morimoto K, Sugizaki T, Arita E et al. Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure. J Biol Chem 2011; 286: 26913-26920.
-
(2011)
J Biol Chem
, vol.286
, pp. 26913-26920
-
-
Watanabe, M.1
Horai, Y.2
Houten, S.M.3
Morimoto, K.4
Sugizaki, T.5
Arita, E.6
-
21
-
-
70349334680
-
The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue
-
Zingaretti MC, Crosta F, Vitali A, Guerrieri M, Frontini A, Cannon B et al. The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue. FASEB J 2009; 23: 3113-3120.
-
(2009)
FASEB J
, vol.23
, pp. 3113-3120
-
-
Zingaretti, M.C.1
Crosta, F.2
Vitali, A.3
Guerrieri, M.4
Frontini, A.5
Cannon, B.6
-
22
-
-
0021319695
-
Brown adipose tissue in the parametrial fat pad of the mouse
-
DOI 10.1016/0014-5793(84)80822-4
-
Young P, Arch JR, Ashwell M. Brown adipose tissue in the parametrial fat pad of the mouse. FEBS Lett 1984; 167: 10-14. (Pubitemid 14198825)
-
(1984)
FEBS Letters
, vol.167
, Issue.1
, pp. 10-14
-
-
Young, P.1
Arch, J.R.S.2
Ashwell, M.3
-
23
-
-
0026075907
-
Convertible adipose tissue in mice
-
Loncar D. Convertible adipose tissue in mice. Cell Tissue Res 1991; 266: 149-161.
-
(1991)
Cell Tissue Res
, vol.266
, pp. 149-161
-
-
Loncar, D.1
-
24
-
-
0027051199
-
Occurrence of brown adipocytes in rat white adipose tissue: Molecular and morphological characterization
-
Cousin B, Cinti S, Morroni M, Raimbault S, Ricquier D, Penicaud L et al. Occurrence of brown adipocytes in rat white adipose tissue: Molecular and morphological characterization. J Cell Sci 1992; 103: 931-942. (Pubitemid 23042237)
-
(1992)
Journal of Cell Science
, vol.103
, Issue.4
, pp. 931-942
-
-
Cousin, B.1
Cinti, S.2
Morroni, M.3
Raimbault, S.4
Ricquier, D.5
Penicaud, L.6
Casteilla, L.7
-
25
-
-
77950226740
-
Chronic peroxisome proliferator-Activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes
-
Petrovic N, Walden TB, Shabalina IG, Timmons JA, Cannon B, Nedergaard J. Chronic peroxisome proliferator-Activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes. J Biol Chem 2010; 285: 7153-7164.
-
(2010)
J Biol Chem
, vol.285
, pp. 7153-7164
-
-
Petrovic, N.1
Walden, T.B.2
Shabalina, I.G.3
Timmons, J.A.4
Cannon, B.5
Nedergaard, J.6
-
26
-
-
84875858745
-
White-To-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma
-
Frontini A, Vitali A, Perugini J, Murano I, Romiti C, Ricquier D et al. White-To-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma. Biochim Biophys Acta 2013; 1831: 950-959.
-
(2013)
Biochim Biophys Acta
, vol.1831
, pp. 950-959
-
-
Frontini, A.1
Vitali, A.2
Perugini, J.3
Murano, I.4
Romiti, C.5
Ricquier, D.6
-
27
-
-
84877263632
-
A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humans
-
Jespersen NZ, Larsen TJ, Peijs L, Daugaard S, Homoe P, Loft A et al. A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humans. Cell Metab 2013; 17: 798-805.
-
(2013)
Cell Metab
, vol.17
, pp. 798-805
-
-
Jespersen, N.Z.1
Larsen, T.J.2
Peijs, L.3
Daugaard, S.4
Homoe, P.5
Loft, A.6
-
29
-
-
64149106016
-
N-3 fatty acids and rosiglitazone improve insulin sensitivity through additive stimulatory effects on muscle glycogen synthesis in mice fed a high-fat diet
-
Kuda O, Jelenik T, Jilkova Z, Flachs P, Rossmeisl M, Hensler M et al. n-3 fatty acids and rosiglitazone improve insulin sensitivity through additive stimulatory effects on muscle glycogen synthesis in mice fed a high-fat diet. Diabetologia 2009; 52: 941-951.
-
(2009)
Diabetologia
, vol.52
, pp. 941-951
-
-
Kuda, O.1
Jelenik, T.2
Jilkova, Z.3
Flachs, P.4
Rossmeisl, M.5
Hensler, M.6
-
30
-
-
84857051608
-
Sex differences during the course of diet-induced obesity in mice: Adipose tissue expandability and glycemic control
-
Medrikova D, Jilkova ZM, Bardova K, Janovska P, Rossmeisl M, Kopecky J. Sex differences during the course of diet-induced obesity in mice: Adipose tissue expandability and glycemic control. Int J Obes 2012; 36: 262-272.
-
(2012)
Int J Obes
, vol.36
, pp. 262-272
-
-
Medrikova, D.1
Jilkova, Z.M.2
Bardova, K.3
Janovska, P.4
Rossmeisl, M.5
Kopecky, J.6
-
31
-
-
67349162620
-
Prevention and reversal of obesity and glucose intolerance in mice by DHA derivatives
-
Rossmeisl M, Jelenik T, Jilkova Z, Slamova K, Kus V, Hensler M et al. Prevention and reversal of obesity and glucose intolerance in mice by DHA derivatives. Obesity 2009; 17: 1023-1031.
-
(2009)
Obesity
, vol.17
, pp. 1023-1031
-
-
Rossmeisl, M.1
Jelenik, T.2
Jilkova, Z.3
Slamova, K.4
Kus, V.5
Hensler, M.6
-
32
-
-
0022345789
-
Effect of dietary fat content on the incidence of obesity among ad libitum fed mice
-
Salmon DM, Flatt JP. Effect of dietary fat content on the incidence of obesity among ad libitum fed mice. Int J Obes 1985; 9: 443-449. (Pubitemid 16189471)
-
(1985)
International Journal of Obesity
, vol.9
, Issue.6
, pp. 443-449
-
-
Salmon, D.M.W.1
Flatt, J.P.2
-
33
-
-
0029894407
-
Reduction of dietary obesity in aP2-Ucp transgenic mice: Mechanism and adipose tissue morphology
-
Kopecky J, Rossmeisl M, Hodny Z, Syrovy I, Horakova M, Kolarova P. Reduction of dietary obesity in aP2-Ucp transgenic mice: Mechanism and adipose tissue morphology. Am J Physiol 1996; 270: E776-E786.
-
(1996)
Am J Physiol
, vol.270
-
-
Kopecky, J.1
Rossmeisl, M.2
Hodny, Z.3
Syrovy, I.4
Horakova, M.5
Kolarova, P.6
-
34
-
-
0022186670
-
Measurement of protein using bicinchoninic acid
-
DOI 10.1016/0003-2697(85)90442-7
-
Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD et al. Measurement of protein using bicinchoninic acid. Anal Biochem 1985; 150: 76-85. (Pubitemid 16258399)
-
(1985)
Analytical Biochemistry
, vol.150
, Issue.1
, pp. 76-85
-
-
Smith, P.K.1
Krohn, R.I.2
Hermanson, G.T.3
-
35
-
-
52649106952
-
Induction of muscle thermogenesis by high-fat diet in mice: Association with obesity-resistance
-
Kus V, Prazak T, Brauner P, Hensler M, Kuda O, Flachs P et al. Induction of muscle thermogenesis by high-fat diet in mice: Association with obesity-resistance. Am J Physiol Endocrinol Metab 2008; 295: E356-E367.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
-
-
Kus, V.1
Prazak, T.2
Brauner, P.3
Hensler, M.4
Kuda, O.5
Flachs, P.6
-
36
-
-
80054122062
-
Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids
-
Flachs P, Ruhl R, Hensler M, Janovska P, Zouhar P, Kus V et al. Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids. Diabetologia 2011; 54: 2626-2638.
-
(2011)
Diabetologia
, vol.54
, pp. 2626-2638
-
-
Flachs, P.1
Ruhl, R.2
Hensler, M.3
Janovska, P.4
Zouhar, P.5
Kus, V.6
-
37
-
-
8944256349
-
New methods for calculating metabolic rate with special reference to protein metabolism
-
Weir JB. New methods for calculating metabolic rate with special reference to protein metabolism. J Physiol 1949; 109: 1-9.
-
(1949)
J Physiol
, vol.109
, pp. 1-9
-
-
Weir, J.B.1
-
38
-
-
84865743048
-
Indirect calorimetry in laboratory mice and rats: Principles, practical considerations, interpretation and perspectives
-
Even PC, Nadkarni NA. Indirect calorimetry in laboratory mice and rats: Principles, practical considerations, interpretation and perspectives. Am J Physiol Regul Integr Comp Physiol 2012; 303: R459-R476.
-
(2012)
Am J Physiol Regul Integr Comp Physiol
, vol.303
-
-
Even, P.C.1
Nadkarni, N.A.2
-
39
-
-
78650945931
-
Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
-
Seale P, Conroe HM, Estall J, Kajimura S, Frontini A, Ishibashi J et al. Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice. J Clin Invest 2011; 121: 96-105.
-
(2011)
J Clin Invest
, vol.121
, pp. 96-105
-
-
Seale, P.1
Conroe, H.M.2
Estall, J.3
Kajimura, S.4
Frontini, A.5
Ishibashi, J.6
-
40
-
-
77449101244
-
A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes
-
Butler AA, Kozak LP. A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes. Diabetes 2010; 59: 323-329.
-
(2010)
Diabetes
, vol.59
, pp. 323-329
-
-
Butler, A.A.1
Kozak, L.P.2
-
41
-
-
18744427205
-
On raising energy expenditure in ob/ob mice
-
DOI 10.1126/science.276.5315.1132
-
Himms-Hagen J. On raising energy expenditure in ob/ob mice. Science 1997; 276: 1132-1133. (Pubitemid 27218125)
-
(1997)
Science
, vol.276
, Issue.5315
, pp. 1132-1133
-
-
Himms-Hagen, J.1
Erickson, J.C.2
Hollopeter, G.3
Palmiter, R.D.4
Pelleymounter, M.A.5
Cullen, M.J.6
Baker, M.B.7
Hecht, R.8
Winters, D.9
Boone, T.10
Collins, F.11
-
42
-
-
78751532080
-
Toward a more complete (and less controversial) understanding of energy expenditure and its role in obesity pathogenesis
-
Kaiyala KJ, Schwartz MW. Toward a more complete (and less controversial) understanding of energy expenditure and its role in obesity pathogenesis. Diabetes 2011; 60: 17-23.
-
(2011)
Diabetes
, vol.60
, pp. 17-23
-
-
Kaiyala, K.J.1
Schwartz, M.W.2
-
43
-
-
79953161490
-
Effects of the gut microbiota on obesity and glucose homeostasis
-
Greiner T, Backhed F. Effects of the gut microbiota on obesity and glucose homeostasis. Trends Endocrinol Metab 2011; 22: 117-123. .
-
(2011)
Trends Endocrinol Metab
, vol.22
, pp. 117-123
-
-
Greiner, T.1
Backhed, F.2
|