TLR9 ligand (CpG oligodeoxynucleotide) induces CLL B-cells to differentiate into CD20+ antibody-secreting cells

Frontiers in Immunology

Volumn 5, Issue JUN, 2014, Pages

  Ghamlouch, Hussein ^a   Ouled Haddou, Hakim ^a   Guyart, Aude ^a   Regnier, Aline ^a,b   Trudel, Stéphanie ^a,b   Claisse, Jean François ^b   Fuentes, Vincent ^a   Royer, Bruno ^a,b   Marolleau, Jean Pierre ^a,b   Gubler, Brigitte ^a,b  

^a UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

^b AMIENS UNIVERSITY HOSPITAL   (France)

Author keywords

Antibody secreting cells; B cell differentiation; CD20; Chronic lymphocytic leukemia; CpG oligodeoxynucleotide; Memory B cell; Poly autoreactive IgM

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; CD19 ANTIGEN; CD20 ANTIBODY; CD20 ANTIGEN; CD27 ANTIGEN; CD38 ANTIGEN; CD40 LIGAND; CD45 ANTIGEN; CPG OLIGODEOXYNUCLEOTIDE; GROWTH ARREST SPECIFIC PROTEIN 6; IMMUNOGLOBULIN M; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 2 RECEPTOR ALPHA; MESSENGER RNA; SYNDECAN 1; TRANSCRIPTION FACTOR PAX5; X BOX BINDING PROTEIN 1;

ADULT; AGED; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CELL STRUCTURE; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CLONAL VARIATION; CONTROLLED STUDY; FEMALE; GENE SEQUENCE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOPHENOTYPING; MALE; PLASMA CELL; REAL TIME POLYMERASE CHAIN REACTION; SECRETORY CELL; SOMATIC HYPERMUTATION; VERY ELDERLY;

EID: 84905641903     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00292     Document Type: Article

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