An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization

Blood

Volumn 114, Issue 25, 2009, Pages 5173-5181

  Jourdan, Michel ^a   Caraux, Anouk ^a   De Vos, John ^a,b,c   Fiol, Geneviève ^b   Larroque, Marion ^b   Cognot, Chantal ^d   Bret, Caroline ^a,b   Duperray, Christophe ^a,b   Hose, Dirk ^e,f   Klein, Bernard ^a,b,c  

^a INSERM   (France)

^b HÔPITAL SAINT ELOI   (France)

^c UNIV MONTPELLIER   (France)

^d MONTPELLIER UNIVERSITY HOSPITAL   (France)

^e UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^f Nationales Centrum fur Tumorerkrankungen   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERFERON REGULATORY FACTOR 4; PROTEIN BCL 6; SYNDECAN 1; TRANSCRIPTION FACTOR PAX5; X BOX BINDING PROTEIN 1; AICDA (ACTIVATION INDUCED CYTIDINE DEAMINASE); AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); BCL6 PROTEIN, HUMAN; CYTIDINE DEAMINASE; DNA BINDING PROTEIN; INTERFERON REGULATORY FACTOR; INTERFERON REGULATORY FACTOR-4; PAX5 PROTEIN, HUMAN; REGULATORY FACTOR X TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOMETRY; DOWN REGULATION; GENE AMPLIFICATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; MEMORY CELL; PHENOTYPE; PLASMA CELL; PRIORITY JOURNAL; B LYMPHOCYTE; BIOLOGICAL MODEL; BONE MARROW CELL; CULTURE TECHNIQUE; CYTOLOGY; DNA MICROARRAY; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENETICS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; IMMUNOPHENOTYPING; METABOLISM; METHODOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETION; STEM CELL; TIME;

B-CELL-SPECIFIC ACTIVATOR PROTEIN; B-LYMPHOCYTES; BONE MARROW CELLS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELLS, CULTURED; CYTIDINE DEAMINASE; DNA-BINDING PROTEINS; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HUMANS; IMMUNOGLOBULINS; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; INTERFERON REGULATORY FACTORS; MODELS, BIOLOGICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLASMA CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELLS; SYNDECAN-1; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 73949109704     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-07-235960     Document Type: Article

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