-
1
-
-
0035051038
-
Model mice for BCR/ABL-positive leukemias
-
Honda H, Hirai H. Model mice for BCR/ABL-positive leukemias. Blood Cells Mol Dis 2001;27:265-78.
-
(2001)
Blood Cells Mol Dis
, vol.27
, pp. 265-278
-
-
Honda, H.1
Hirai, H.2
-
2
-
-
33749524667
-
Dynamic modeling of imatinib-treated chronic myeloid leukemia: Functional insights and clinical implications
-
Roeder I, Horn M, Glauche I, Hochhaus A, Mueller MC, Loeffler M. Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications. Nat Med 2006;12:1181-4.
-
(2006)
Nat Med
, vol.12
, pp. 1181-1184
-
-
Roeder, I.1
Horn, M.2
Glauche, I.3
Hochhaus, A.4
Mueller, M.C.5
Loeffler, M.6
-
3
-
-
34249676964
-
Chronic myeloid leukaemia as a model of disease evolution in human cancer
-
Melo JV, Barnes DJ. Chronic myeloid leukaemia as a model of disease evolution in human cancer. Nat Rev Cancer 2007;7:441-53.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 441-453
-
-
Melo, J.V.1
Barnes, D.J.2
-
4
-
-
77954977940
-
Chronic myeloid leukemia: Mechanisms of blastic transformation
-
Perrotti D, Jamieson C, Goldman J, Skorski T. Chronic myeloid leukemia: mechanisms of blastic transformation. J Clin Invest 2010;120:2254-64.
-
(2010)
J Clin Invest
, vol.120
, pp. 2254-2264
-
-
Perrotti, D.1
Jamieson, C.2
Goldman, J.3
Skorski, T.4
-
5
-
-
34447631168
-
Oxyl radicals, redox-sensitive signalling cascades and antioxidants
-
Genestra M. Oxyl radicals, redox-sensitive signalling cascades and antioxidants. Cell Signal 2007;19:1807-19.
-
(2007)
Cell Signal
, vol.19
, pp. 1807-1819
-
-
Genestra, M.1
-
6
-
-
84856951081
-
Reactive oxygen species: Are they important for haematopoiesis?
-
Sardina JL, Lopez-Ruano G, Sanchez-Sanchez B, Llanillo M, Hernandez-Hernandez A. Reactive oxygen species: are they important for haematopoiesis? Crit Rev Oncol Hematol 2012;81:257-74.
-
(2012)
Crit Rev Oncol Hematol
, vol.81
, pp. 257-274
-
-
Sardina, J.L.1
Lopez-Ruano, G.2
Sanchez-Sanchez, B.3
Llanillo, M.4
Hernandez-Hernandez, A.5
-
7
-
-
0026021362
-
Production of large amounts of hydrogen peroxide by human tumor cells
-
Szatrowski TP, Nathan CF. Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res 1991;51:794-8.
-
(1991)
Cancer Res
, vol.51
, pp. 794-798
-
-
Szatrowski, T.P.1
Nathan, C.F.2
-
10
-
-
33846117134
-
The signaling mechanism of ROS in tumor progression
-
Wu WS. The signaling mechanism of ROS in tumor progression. Cancer Metastasis Rev 2006;25:695-705.
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 695-705
-
-
Wu, W.S.1
-
11
-
-
50649087954
-
Genomic instability in myeloid malignancies: Increased reactive oxygen species (ROS), DNA double strand breaks (DSBs) and error-prone repair
-
Sallmyr A, Fan J, Rassool FV. Genomic instability in myeloid malignancies: increased reactive oxygen species (ROS), DNA double strand breaks (DSBs) and error-prone repair. Cancer Lett 2008;270:1-9.
-
(2008)
Cancer Lett
, vol.270
, pp. 1-9
-
-
Sallmyr, A.1
Fan, J.2
Rassool, F.V.3
-
12
-
-
0034637599
-
The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells
-
Sattler M, Verma S, Shrikhande G, Byrne CH, Pride YB, Winkler T, et al. The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells. J Biol Chem 2000;275:24273-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 24273-24278
-
-
Sattler, M.1
Verma, S.2
Shrikhande, G.3
Byrne, C.H.4
Pride, Y.B.5
Winkler, T.6
-
13
-
-
79751534683
-
NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases
-
Reddy MM, Fernandes MS, Salgia R, Levine RL, Griffin JD, Sattler M. NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases. Leukemia 2011;25:281-9.
-
(2011)
Leukemia
, vol.25
, pp. 281-289
-
-
Reddy, M.M.1
Fernandes, M.S.2
Salgia, R.3
Levine, R.L.4
Griffin, J.D.5
Sattler, M.6
-
14
-
-
68749117502
-
Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway
-
Naughton R, Quiney C, Turner SD, Cotter TG. Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway. Leukemia 2009;23:1432-40.
-
(2009)
Leukemia
, vol.23
, pp. 1432-1440
-
-
Naughton, R.1
Quiney, C.2
Turner, S.D.3
Cotter, T.G.4
-
15
-
-
52049084111
-
BCR/ABL and other kinases from chronic myeloproliferative disorders stimulate single-strand annealing, an unfaithful DNA double-strand break repair
-
Cramer K, Nieborowska-Skorska M, Koptyra M, Slupianek A, Penserga ET, Eaves CJ, et al. BCR/ABL and other kinases from chronic myeloproliferative disorders stimulate single-strand annealing, an unfaithful DNA double-strand break repair. Cancer Res 2008;68:6884-8.
-
(2008)
Cancer Res
, vol.68
, pp. 6884-6888
-
-
Cramer, K.1
Nieborowska-Skorska, M.2
Koptyra, M.3
Slupianek, A.4
Penserga, E.T.5
Eaves, C.J.6
-
16
-
-
33745608455
-
BCR/ABL kinase induces self-mutagenesis via reactive oxygen species to encode imatinib resistance
-
Koptyra M, Falinski R, Nowicki MO, Stoklosa T, Majsterek I, Nieborowska-Skorska M, et al. BCR/ABL kinase induces self-mutagenesis via reactive oxygen species to encode imatinib resistance. Blood 2006;108:319-27.
-
(2006)
Blood
, vol.108
, pp. 319-327
-
-
Koptyra, M.1
Falinski, R.2
Nowicki, M.O.3
Stoklosa, T.4
Majsterek, I.5
Nieborowska-Skorska, M.6
-
17
-
-
9444264703
-
BCR/ABL oncogenic kinase promotes unfaithful repair of the reactive oxygen species-dependent DNA double-strand breaks
-
Nowicki MO, Falinski R, Koptyra M, Slupianek A, Stoklosa T, Gloc E, et al. BCR/ABL oncogenic kinase promotes unfaithful repair of the reactive oxygen species-dependent DNA double-strand breaks. Blood 2004;104:3746-53.
-
(2004)
Blood
, vol.104
, pp. 3746-3753
-
-
Nowicki, M.O.1
Falinski, R.2
Koptyra, M.3
Slupianek, A.4
Stoklosa, T.5
Gloc, E.6
-
18
-
-
20844448882
-
Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species
-
Kim JH, Chu SC, Gramlich JL, Pride YB, Babendreier E, Chauhan D, et al. Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species. Blood 2005;105:1717-23.
-
(2005)
Blood
, vol.105
, pp. 1717-1723
-
-
Kim, J.H.1
Chu, S.C.2
Gramlich, J.L.3
Pride, Y.B.4
Babendreier, E.5
Chauhan, D.6
-
19
-
-
47749151450
-
Biological roles for the NOX family NADPH oxidases
-
Nauseef WM. Biological roles for the NOX family NADPH oxidases. J Biol Chem 2008;283:16961-5.
-
(2008)
J Biol Chem
, vol.283
, pp. 16961-16965
-
-
Nauseef, W.M.1
-
20
-
-
41149150716
-
NADPH oxidases, reactive oxygen species, and hypertension: Clinical implications and therapeutic possibilities
-
Paravicini TM, Touyz RM. NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities. Diabetes Care 2008;31 Suppl 2:S170-80.
-
(2008)
Diabetes Care
, vol.31
, Issue.SUPPL. 2
-
-
Paravicini, T.M.1
Touyz, R.M.2
-
21
-
-
84866425239
-
Aiding and abetting roles of NOX oxidases in cellular transformation
-
Block K, Gorin Y. Aiding and abetting roles of NOX oxidases in cellular transformation. Nat Rev Cancer 2012;12:627-37.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 627-637
-
-
Block, K.1
Gorin, Y.2
-
22
-
-
84874618204
-
Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts
-
Doroshow JH, Gaur S, Markel S, Lu J, Van Balgooy J, Synold TW, et al. Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts. Free Radic Biol Med 2013;57:162-75.
-
(2013)
Free Radic Biol Med
, vol.57
, pp. 162-175
-
-
Doroshow, J.H.1
Gaur, S.2
Markel, S.3
Lu, J.4
Van Balgooy, J.5
Synold, T.W.6
-
23
-
-
47349086632
-
Optimization of mesenchymal stem cell expansion procedures by cell separation and culture conditions modification
-
Carrancio S, Lopez-Holgado N, Sanchez-Guijo FM, Villaron E, Barbado V, Tabera S, et al. Optimization of mesenchymal stem cell expansion procedures by cell separation and culture conditions modification. Exp Hematol 2008;36:1014-21.
-
(2008)
Exp Hematol
, vol.36
, pp. 1014-1021
-
-
Carrancio, S.1
Lopez-Holgado, N.2
Sanchez-Guijo, F.M.3
Villaron, E.4
Barbado, V.5
Tabera, S.6
-
24
-
-
33644924043
-
Characterization of p87C3G, a novel, truncated C3G isoform that is overexpressed in chronic myeloid leukemia and interacts with Bcr-Abl
-
Gutierrez-Berzal J, Castellano E, Martin-Encabo S, Gutierrez-Cianca N, Hernandez JM, Santos E, et al. Characterization of p87C3G, a novel, truncated C3G isoform that is overexpressed in chronic myeloid leukemia and interacts with Bcr-Abl. Exp Cell Res 2006;312:938-48.
-
(2006)
Exp Cell Res
, vol.312
, pp. 938-948
-
-
Gutierrez-Berzal, J.1
Castellano, E.2
Martin-Encabo, S.3
Gutierrez-Cianca, N.4
Hernandez, J.M.5
Santos, E.6
-
25
-
-
78349303803
-
P22Phox-dependent NADPH oxidase activity is required for megakaryocytic differentiation
-
Sardina JL, Lopez-Ruano G, Sanchez-Abarca LI, Perez-Simon JA, Gaztelumendi A, Trigueros C, et al. p22phox-dependent NADPH oxidase activity is required for megakaryocytic differentiation. Cell Death Differ 2010;17:1842-54.
-
(2010)
Cell Death Differ
, vol.17
, pp. 1842-1854
-
-
Sardina, J.L.1
Lopez-Ruano, G.2
Sanchez-Abarca, L.I.3
Perez-Simon, J.A.4
Gaztelumendi, A.5
Trigueros, C.6
-
26
-
-
76549129820
-
Drug combination studies and their synergy quantification using the Chou-Talalay method
-
Chou TC. Drug combination studies and their synergy quantification using the Chou-Talalay method. Cancer Res 2010;70:440-6.
-
(2010)
Cancer Res
, vol.70
, pp. 440-446
-
-
Chou, T.C.1
-
27
-
-
0032520986
-
Development of acute lymphoblastic leukemia and myeloproliferative disorder in transgenic mice expressing p210bcr/abl: A novel transgenic model for human Ph1-positive leukemias
-
Honda H, Oda H, Suzuki T, Takahashi T, Witte ON, Ozawa K, et al. Development of acute lymphoblastic leukemia and myeloproliferative disorder in transgenic mice expressing p210bcr/abl: a novel transgenic model for human Ph1-positive leukemias. Blood 1998;91:2067-75.
-
(1998)
Blood
, vol.91
, pp. 2067-2075
-
-
Honda, H.1
Oda, H.2
Suzuki, T.3
Takahashi, T.4
Witte, O.N.5
Ozawa, K.6
-
28
-
-
28244459619
-
Knockdown of glutamate-cysteine ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neurons
-
Diaz-Hernandez JI, Almeida A, Delgado-Esteban M, Fernandez E, Bolanos JP. Knockdown of glutamate-cysteine ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neurons. J Biol Chem 2005;280:38992-9001.
-
(2005)
J Biol Chem
, vol.280
, pp. 38992-39001
-
-
Diaz-Hernandez, J.I.1
Almeida, A.2
Delgado-Esteban, M.3
Fernandez, E.4
Bolanos, J.P.5
-
29
-
-
58149347478
-
Classical inhibitors of NOX NAD (P) H oxidases are not specific
-
Aldieri E, Riganti C, Polimeni M, Gazzano E, Lussiana C, Campia I, et al. Classical inhibitors of NOX NAD (P) H oxidases are not specific. Curr Drug Metab 2008;9:686-96.
-
(2008)
Curr Drug Metab
, vol.9
, pp. 686-696
-
-
Aldieri, E.1
Riganti, C.2
Polimeni, M.3
Gazzano, E.4
Lussiana, C.5
Campia, I.6
-
30
-
-
77956813371
-
Comparative pharmacology of chemically distinct NADPH oxidase inhibitors
-
Wind S, Beuerlein K, Eucker T, Muller H, Scheurer P, Armitage ME, et al. Comparative pharmacology of chemically distinct NADPH oxidase inhibitors. Br J Pharmacol 2010;161:885-98.
-
(2010)
Br J Pharmacol
, vol.161
, pp. 885-898
-
-
Wind, S.1
Beuerlein, K.2
Eucker, T.3
Muller, H.4
Scheurer, P.5
Armitage, M.E.6
-
31
-
-
70449133798
-
Redox control of the cell cycle in health and disease
-
Sarsour EH, Kumar MG, Chaudhuri L, Kalen AL, Goswami PC. Redox control of the cell cycle in health and disease. Antioxid Redox Signal 2009;11:2985-3011.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2985-3011
-
-
Sarsour, E.H.1
Kumar, M.G.2
Chaudhuri, L.3
Kalen, A.L.4
Goswami, P.C.5
-
32
-
-
0032532562
-
Regulation of Bcr-Abl-induced SAP kinase activity and transformation by the SHPTP1 protein tyrosine phosphatase
-
Liedtke M, Pandey P, Kumar S, Kharbanda S, Kufe D. Regulation of Bcr-Abl-induced SAP kinase activity and transformation by the SHPTP1 protein tyrosine phosphatase. Oncogene 1998;17:1889-92.
-
(1998)
Oncogene
, vol.17
, pp. 1889-1892
-
-
Liedtke, M.1
Pandey, P.2
Kumar, S.3
Kharbanda, S.4
Kufe, D.5
-
33
-
-
78049231394
-
C-Phycocyanin inhibits MDR1 through reactive oxygen species and cyclooxygenase-2 mediated pathways in human hepatocellular carcinoma cell line
-
Nishanth RP, Ramakrishna BS, Jyotsna RG, Roy KR, Reddy GV, Reddy PK, et al. C-Phycocyanin inhibits MDR1 through reactive oxygen species and cyclooxygenase-2 mediated pathways in human hepatocellular carcinoma cell line. Eur J Pharmacol 2010;649:74-83.
-
(2010)
Eur J Pharmacol
, vol.649
, pp. 74-83
-
-
Nishanth, R.P.1
Ramakrishna, B.S.2
Jyotsna, R.G.3
Roy, K.R.4
Reddy, G.V.5
Reddy, P.K.6
-
34
-
-
35748943189
-
Rac guanosine triphosphatases represent integrating molecular therapeutic targets for BCR-ABL-induced myeloproliferative disease
-
Thomas EK, Cancelas JA, Chae HD, Cox AD, Keller PJ, Perrotti D, et al. Rac guanosine triphosphatases represent integrating molecular therapeutic targets for BCR-ABL-induced myeloproliferative disease. Cancer Cell 2007;12:467-78.
-
(2007)
Cancer Cell
, vol.12
, pp. 467-478
-
-
Thomas, E.K.1
Cancelas, J.A.2
Chae, H.D.3
Cox, A.D.4
Keller, P.J.5
Perrotti, D.6
-
35
-
-
0033515426
-
Phosphorylation of histone H3 is required for proper chromosome condensation and segregation
-
Wei Y, Yu L, Bowen J, Gorovsky MA, Allis CD. Phosphorylation of histone H3 is required for proper chromosome condensation and segregation. Cell 1999;97:99-109.
-
(1999)
Cell
, vol.97
, pp. 99-109
-
-
Wei, Y.1
Yu, L.2
Bowen, J.3
Gorovsky, M.A.4
Allis, C.D.5
-
36
-
-
0030561427
-
Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control
-
Lew DJ, Kornbluth S. Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control. Curr Opin Cell Biol 1996;8:795-804.
-
(1996)
Curr Opin Cell Biol
, vol.8
, pp. 795-804
-
-
Lew, D.J.1
Kornbluth, S.2
-
37
-
-
33846794822
-
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
-
Bedard K, Krause KH. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev 2007;87:245-313.
-
(2007)
Physiol Rev
, vol.87
, pp. 245-313
-
-
Bedard, K.1
Krause, K.H.2
-
38
-
-
33846130574
-
Bone-marrow derived hematopoietic stem/progenitor cells express multiple isoforms of NADPH oxidase and produce constitutively reactive oxygen species
-
Piccoli C, D'Aprile A, Ripoli M, Scrima R, Lecce L, Boffoli D, et al. Bone-marrow derived hematopoietic stem/progenitor cells express multiple isoforms of NADPH oxidase and produce constitutively reactive oxygen species. Biochem Biophys Res Commun 2007;353:965-72.
-
(2007)
Biochem Biophys Res Commun
, vol.353
, pp. 965-972
-
-
Piccoli, C.1
D'Aprile, A.2
Ripoli, M.3
Scrima, R.4
Lecce, L.5
Boffoli, D.6
-
39
-
-
84874452686
-
Redox control of leukemia: From molecular mechanisms to therapeutic opportunities
-
Irwin ME, Rivera-Del Valle N, Chandra J. Redox control of leukemia: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal 2013;18:1349-83.
-
(2013)
Antioxid Redox Signal
, vol.18
, pp. 1349-1383
-
-
Irwin, M.E.1
Rivera-Del Valle, N.2
Chandra, J.3
-
40
-
-
84891672388
-
Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling
-
Hole PS, Zabkiewicz J, Munje C, Newton Z, Pearn L, White P, et al. Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling. Blood 2013;122:3322-30.
-
(2013)
Blood
, vol.122
, pp. 3322-3330
-
-
Hole, P.S.1
Zabkiewicz, J.2
Munje, C.3
Newton, Z.4
Pearn, L.5
White, P.6
-
41
-
-
0031795520
-
Antioxidant inhibitors for cancer therapy
-
Kong Q, Lillehei KO. Antioxidant inhibitors for cancer therapy. Med Hypotheses 1998;51:405-9.
-
(1998)
Med Hypotheses
, vol.51
, pp. 405-409
-
-
Kong, Q.1
Lillehei, K.O.2
-
42
-
-
67650071137
-
Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach?
-
Trachootham D, Alexandre J, Huang P. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat Rev Drug Discov 2009;8:579-91.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 579-591
-
-
Trachootham, D.1
Alexandre, J.2
Huang, P.3
-
43
-
-
0028125095
-
Protective role of manganese superoxide dismutase against cigarette smoke-induced cytotoxicity
-
St Clair DK, Jordan JA, Wan XS, Gairola CG. Protective role of manganese superoxide dismutase against cigarette smoke-induced cytotoxicity. J Toxicol Environ Health 1994;43:239-49.
-
(1994)
J Toxicol Environ Health
, vol.43
, pp. 239-249
-
-
St Clair, D.K.1
Jordan, J.A.2
Wan, X.S.3
Gairola, C.G.4
|