메뉴 건너뛰기




Volumn 20, Issue 15, 2014, Pages 4014-4025

NADPH oxidases as therapeutic targets in chronic myelogenous leukemia

Author keywords

[No Author keywords available]

Indexed keywords

APOCYNIN; DIPHENYLIODONIUM SALT; ENZYME INHIBITOR; IMATINIB; NILOTINIB; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; VAS 3947; BCR ABL PROTEIN; MESSENGER RNA; REACTIVE OXYGEN METABOLITE;

EID: 84905514248     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-13-3044     Document Type: Article
Times cited : (38)

References (43)
  • 1
    • 0035051038 scopus 로고    scopus 로고
    • Model mice for BCR/ABL-positive leukemias
    • Honda H, Hirai H. Model mice for BCR/ABL-positive leukemias. Blood Cells Mol Dis 2001;27:265-78.
    • (2001) Blood Cells Mol Dis , vol.27 , pp. 265-278
    • Honda, H.1    Hirai, H.2
  • 2
    • 33749524667 scopus 로고    scopus 로고
    • Dynamic modeling of imatinib-treated chronic myeloid leukemia: Functional insights and clinical implications
    • Roeder I, Horn M, Glauche I, Hochhaus A, Mueller MC, Loeffler M. Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications. Nat Med 2006;12:1181-4.
    • (2006) Nat Med , vol.12 , pp. 1181-1184
    • Roeder, I.1    Horn, M.2    Glauche, I.3    Hochhaus, A.4    Mueller, M.C.5    Loeffler, M.6
  • 3
    • 34249676964 scopus 로고    scopus 로고
    • Chronic myeloid leukaemia as a model of disease evolution in human cancer
    • Melo JV, Barnes DJ. Chronic myeloid leukaemia as a model of disease evolution in human cancer. Nat Rev Cancer 2007;7:441-53.
    • (2007) Nat Rev Cancer , vol.7 , pp. 441-453
    • Melo, J.V.1    Barnes, D.J.2
  • 4
    • 77954977940 scopus 로고    scopus 로고
    • Chronic myeloid leukemia: Mechanisms of blastic transformation
    • Perrotti D, Jamieson C, Goldman J, Skorski T. Chronic myeloid leukemia: mechanisms of blastic transformation. J Clin Invest 2010;120:2254-64.
    • (2010) J Clin Invest , vol.120 , pp. 2254-2264
    • Perrotti, D.1    Jamieson, C.2    Goldman, J.3    Skorski, T.4
  • 5
    • 34447631168 scopus 로고    scopus 로고
    • Oxyl radicals, redox-sensitive signalling cascades and antioxidants
    • Genestra M. Oxyl radicals, redox-sensitive signalling cascades and antioxidants. Cell Signal 2007;19:1807-19.
    • (2007) Cell Signal , vol.19 , pp. 1807-1819
    • Genestra, M.1
  • 7
    • 0026021362 scopus 로고
    • Production of large amounts of hydrogen peroxide by human tumor cells
    • Szatrowski TP, Nathan CF. Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res 1991;51:794-8.
    • (1991) Cancer Res , vol.51 , pp. 794-798
    • Szatrowski, T.P.1    Nathan, C.F.2
  • 9
    • 0348049803 scopus 로고    scopus 로고
    • Reactive oxygen species in oncogenic transformation
    • Behrend L, Henderson G, Zwacka RM. Reactive oxygen species in oncogenic transformation. Biochem Soc Trans 2003;31:1441-4.
    • (2003) Biochem Soc Trans , vol.31 , pp. 1441-1444
    • Behrend, L.1    Henderson, G.2    Zwacka, R.M.3
  • 10
    • 33846117134 scopus 로고    scopus 로고
    • The signaling mechanism of ROS in tumor progression
    • Wu WS. The signaling mechanism of ROS in tumor progression. Cancer Metastasis Rev 2006;25:695-705.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 695-705
    • Wu, W.S.1
  • 11
    • 50649087954 scopus 로고    scopus 로고
    • Genomic instability in myeloid malignancies: Increased reactive oxygen species (ROS), DNA double strand breaks (DSBs) and error-prone repair
    • Sallmyr A, Fan J, Rassool FV. Genomic instability in myeloid malignancies: increased reactive oxygen species (ROS), DNA double strand breaks (DSBs) and error-prone repair. Cancer Lett 2008;270:1-9.
    • (2008) Cancer Lett , vol.270 , pp. 1-9
    • Sallmyr, A.1    Fan, J.2    Rassool, F.V.3
  • 12
    • 0034637599 scopus 로고    scopus 로고
    • The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells
    • Sattler M, Verma S, Shrikhande G, Byrne CH, Pride YB, Winkler T, et al. The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells. J Biol Chem 2000;275:24273-8.
    • (2000) J Biol Chem , vol.275 , pp. 24273-24278
    • Sattler, M.1    Verma, S.2    Shrikhande, G.3    Byrne, C.H.4    Pride, Y.B.5    Winkler, T.6
  • 13
    • 79751534683 scopus 로고    scopus 로고
    • NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases
    • Reddy MM, Fernandes MS, Salgia R, Levine RL, Griffin JD, Sattler M. NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases. Leukemia 2011;25:281-9.
    • (2011) Leukemia , vol.25 , pp. 281-289
    • Reddy, M.M.1    Fernandes, M.S.2    Salgia, R.3    Levine, R.L.4    Griffin, J.D.5    Sattler, M.6
  • 14
    • 68749117502 scopus 로고    scopus 로고
    • Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway
    • Naughton R, Quiney C, Turner SD, Cotter TG. Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway. Leukemia 2009;23:1432-40.
    • (2009) Leukemia , vol.23 , pp. 1432-1440
    • Naughton, R.1    Quiney, C.2    Turner, S.D.3    Cotter, T.G.4
  • 15
    • 52049084111 scopus 로고    scopus 로고
    • BCR/ABL and other kinases from chronic myeloproliferative disorders stimulate single-strand annealing, an unfaithful DNA double-strand break repair
    • Cramer K, Nieborowska-Skorska M, Koptyra M, Slupianek A, Penserga ET, Eaves CJ, et al. BCR/ABL and other kinases from chronic myeloproliferative disorders stimulate single-strand annealing, an unfaithful DNA double-strand break repair. Cancer Res 2008;68:6884-8.
    • (2008) Cancer Res , vol.68 , pp. 6884-6888
    • Cramer, K.1    Nieborowska-Skorska, M.2    Koptyra, M.3    Slupianek, A.4    Penserga, E.T.5    Eaves, C.J.6
  • 16
    • 33745608455 scopus 로고    scopus 로고
    • BCR/ABL kinase induces self-mutagenesis via reactive oxygen species to encode imatinib resistance
    • Koptyra M, Falinski R, Nowicki MO, Stoklosa T, Majsterek I, Nieborowska-Skorska M, et al. BCR/ABL kinase induces self-mutagenesis via reactive oxygen species to encode imatinib resistance. Blood 2006;108:319-27.
    • (2006) Blood , vol.108 , pp. 319-327
    • Koptyra, M.1    Falinski, R.2    Nowicki, M.O.3    Stoklosa, T.4    Majsterek, I.5    Nieborowska-Skorska, M.6
  • 17
    • 9444264703 scopus 로고    scopus 로고
    • BCR/ABL oncogenic kinase promotes unfaithful repair of the reactive oxygen species-dependent DNA double-strand breaks
    • Nowicki MO, Falinski R, Koptyra M, Slupianek A, Stoklosa T, Gloc E, et al. BCR/ABL oncogenic kinase promotes unfaithful repair of the reactive oxygen species-dependent DNA double-strand breaks. Blood 2004;104:3746-53.
    • (2004) Blood , vol.104 , pp. 3746-3753
    • Nowicki, M.O.1    Falinski, R.2    Koptyra, M.3    Slupianek, A.4    Stoklosa, T.5    Gloc, E.6
  • 18
    • 20844448882 scopus 로고    scopus 로고
    • Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species
    • Kim JH, Chu SC, Gramlich JL, Pride YB, Babendreier E, Chauhan D, et al. Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species. Blood 2005;105:1717-23.
    • (2005) Blood , vol.105 , pp. 1717-1723
    • Kim, J.H.1    Chu, S.C.2    Gramlich, J.L.3    Pride, Y.B.4    Babendreier, E.5    Chauhan, D.6
  • 19
    • 47749151450 scopus 로고    scopus 로고
    • Biological roles for the NOX family NADPH oxidases
    • Nauseef WM. Biological roles for the NOX family NADPH oxidases. J Biol Chem 2008;283:16961-5.
    • (2008) J Biol Chem , vol.283 , pp. 16961-16965
    • Nauseef, W.M.1
  • 20
    • 41149150716 scopus 로고    scopus 로고
    • NADPH oxidases, reactive oxygen species, and hypertension: Clinical implications and therapeutic possibilities
    • Paravicini TM, Touyz RM. NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities. Diabetes Care 2008;31 Suppl 2:S170-80.
    • (2008) Diabetes Care , vol.31 , Issue.SUPPL. 2
    • Paravicini, T.M.1    Touyz, R.M.2
  • 21
    • 84866425239 scopus 로고    scopus 로고
    • Aiding and abetting roles of NOX oxidases in cellular transformation
    • Block K, Gorin Y. Aiding and abetting roles of NOX oxidases in cellular transformation. Nat Rev Cancer 2012;12:627-37.
    • (2012) Nat Rev Cancer , vol.12 , pp. 627-637
    • Block, K.1    Gorin, Y.2
  • 22
    • 84874618204 scopus 로고    scopus 로고
    • Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts
    • Doroshow JH, Gaur S, Markel S, Lu J, Van Balgooy J, Synold TW, et al. Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts. Free Radic Biol Med 2013;57:162-75.
    • (2013) Free Radic Biol Med , vol.57 , pp. 162-175
    • Doroshow, J.H.1    Gaur, S.2    Markel, S.3    Lu, J.4    Van Balgooy, J.5    Synold, T.W.6
  • 23
    • 47349086632 scopus 로고    scopus 로고
    • Optimization of mesenchymal stem cell expansion procedures by cell separation and culture conditions modification
    • Carrancio S, Lopez-Holgado N, Sanchez-Guijo FM, Villaron E, Barbado V, Tabera S, et al. Optimization of mesenchymal stem cell expansion procedures by cell separation and culture conditions modification. Exp Hematol 2008;36:1014-21.
    • (2008) Exp Hematol , vol.36 , pp. 1014-1021
    • Carrancio, S.1    Lopez-Holgado, N.2    Sanchez-Guijo, F.M.3    Villaron, E.4    Barbado, V.5    Tabera, S.6
  • 24
    • 33644924043 scopus 로고    scopus 로고
    • Characterization of p87C3G, a novel, truncated C3G isoform that is overexpressed in chronic myeloid leukemia and interacts with Bcr-Abl
    • Gutierrez-Berzal J, Castellano E, Martin-Encabo S, Gutierrez-Cianca N, Hernandez JM, Santos E, et al. Characterization of p87C3G, a novel, truncated C3G isoform that is overexpressed in chronic myeloid leukemia and interacts with Bcr-Abl. Exp Cell Res 2006;312:938-48.
    • (2006) Exp Cell Res , vol.312 , pp. 938-948
    • Gutierrez-Berzal, J.1    Castellano, E.2    Martin-Encabo, S.3    Gutierrez-Cianca, N.4    Hernandez, J.M.5    Santos, E.6
  • 26
    • 76549129820 scopus 로고    scopus 로고
    • Drug combination studies and their synergy quantification using the Chou-Talalay method
    • Chou TC. Drug combination studies and their synergy quantification using the Chou-Talalay method. Cancer Res 2010;70:440-6.
    • (2010) Cancer Res , vol.70 , pp. 440-446
    • Chou, T.C.1
  • 27
    • 0032520986 scopus 로고    scopus 로고
    • Development of acute lymphoblastic leukemia and myeloproliferative disorder in transgenic mice expressing p210bcr/abl: A novel transgenic model for human Ph1-positive leukemias
    • Honda H, Oda H, Suzuki T, Takahashi T, Witte ON, Ozawa K, et al. Development of acute lymphoblastic leukemia and myeloproliferative disorder in transgenic mice expressing p210bcr/abl: a novel transgenic model for human Ph1-positive leukemias. Blood 1998;91:2067-75.
    • (1998) Blood , vol.91 , pp. 2067-2075
    • Honda, H.1    Oda, H.2    Suzuki, T.3    Takahashi, T.4    Witte, O.N.5    Ozawa, K.6
  • 28
    • 28244459619 scopus 로고    scopus 로고
    • Knockdown of glutamate-cysteine ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neurons
    • Diaz-Hernandez JI, Almeida A, Delgado-Esteban M, Fernandez E, Bolanos JP. Knockdown of glutamate-cysteine ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neurons. J Biol Chem 2005;280:38992-9001.
    • (2005) J Biol Chem , vol.280 , pp. 38992-39001
    • Diaz-Hernandez, J.I.1    Almeida, A.2    Delgado-Esteban, M.3    Fernandez, E.4    Bolanos, J.P.5
  • 32
    • 0032532562 scopus 로고    scopus 로고
    • Regulation of Bcr-Abl-induced SAP kinase activity and transformation by the SHPTP1 protein tyrosine phosphatase
    • Liedtke M, Pandey P, Kumar S, Kharbanda S, Kufe D. Regulation of Bcr-Abl-induced SAP kinase activity and transformation by the SHPTP1 protein tyrosine phosphatase. Oncogene 1998;17:1889-92.
    • (1998) Oncogene , vol.17 , pp. 1889-1892
    • Liedtke, M.1    Pandey, P.2    Kumar, S.3    Kharbanda, S.4    Kufe, D.5
  • 33
    • 78049231394 scopus 로고    scopus 로고
    • C-Phycocyanin inhibits MDR1 through reactive oxygen species and cyclooxygenase-2 mediated pathways in human hepatocellular carcinoma cell line
    • Nishanth RP, Ramakrishna BS, Jyotsna RG, Roy KR, Reddy GV, Reddy PK, et al. C-Phycocyanin inhibits MDR1 through reactive oxygen species and cyclooxygenase-2 mediated pathways in human hepatocellular carcinoma cell line. Eur J Pharmacol 2010;649:74-83.
    • (2010) Eur J Pharmacol , vol.649 , pp. 74-83
    • Nishanth, R.P.1    Ramakrishna, B.S.2    Jyotsna, R.G.3    Roy, K.R.4    Reddy, G.V.5    Reddy, P.K.6
  • 34
    • 35748943189 scopus 로고    scopus 로고
    • Rac guanosine triphosphatases represent integrating molecular therapeutic targets for BCR-ABL-induced myeloproliferative disease
    • Thomas EK, Cancelas JA, Chae HD, Cox AD, Keller PJ, Perrotti D, et al. Rac guanosine triphosphatases represent integrating molecular therapeutic targets for BCR-ABL-induced myeloproliferative disease. Cancer Cell 2007;12:467-78.
    • (2007) Cancer Cell , vol.12 , pp. 467-478
    • Thomas, E.K.1    Cancelas, J.A.2    Chae, H.D.3    Cox, A.D.4    Keller, P.J.5    Perrotti, D.6
  • 35
    • 0033515426 scopus 로고    scopus 로고
    • Phosphorylation of histone H3 is required for proper chromosome condensation and segregation
    • Wei Y, Yu L, Bowen J, Gorovsky MA, Allis CD. Phosphorylation of histone H3 is required for proper chromosome condensation and segregation. Cell 1999;97:99-109.
    • (1999) Cell , vol.97 , pp. 99-109
    • Wei, Y.1    Yu, L.2    Bowen, J.3    Gorovsky, M.A.4    Allis, C.D.5
  • 36
    • 0030561427 scopus 로고    scopus 로고
    • Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control
    • Lew DJ, Kornbluth S. Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control. Curr Opin Cell Biol 1996;8:795-804.
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 795-804
    • Lew, D.J.1    Kornbluth, S.2
  • 37
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
    • Bedard K, Krause KH. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev 2007;87:245-313.
    • (2007) Physiol Rev , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 38
    • 33846130574 scopus 로고    scopus 로고
    • Bone-marrow derived hematopoietic stem/progenitor cells express multiple isoforms of NADPH oxidase and produce constitutively reactive oxygen species
    • Piccoli C, D'Aprile A, Ripoli M, Scrima R, Lecce L, Boffoli D, et al. Bone-marrow derived hematopoietic stem/progenitor cells express multiple isoforms of NADPH oxidase and produce constitutively reactive oxygen species. Biochem Biophys Res Commun 2007;353:965-72.
    • (2007) Biochem Biophys Res Commun , vol.353 , pp. 965-972
    • Piccoli, C.1    D'Aprile, A.2    Ripoli, M.3    Scrima, R.4    Lecce, L.5    Boffoli, D.6
  • 39
    • 84874452686 scopus 로고    scopus 로고
    • Redox control of leukemia: From molecular mechanisms to therapeutic opportunities
    • Irwin ME, Rivera-Del Valle N, Chandra J. Redox control of leukemia: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal 2013;18:1349-83.
    • (2013) Antioxid Redox Signal , vol.18 , pp. 1349-1383
    • Irwin, M.E.1    Rivera-Del Valle, N.2    Chandra, J.3
  • 40
    • 84891672388 scopus 로고    scopus 로고
    • Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling
    • Hole PS, Zabkiewicz J, Munje C, Newton Z, Pearn L, White P, et al. Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling. Blood 2013;122:3322-30.
    • (2013) Blood , vol.122 , pp. 3322-3330
    • Hole, P.S.1    Zabkiewicz, J.2    Munje, C.3    Newton, Z.4    Pearn, L.5    White, P.6
  • 41
    • 0031795520 scopus 로고    scopus 로고
    • Antioxidant inhibitors for cancer therapy
    • Kong Q, Lillehei KO. Antioxidant inhibitors for cancer therapy. Med Hypotheses 1998;51:405-9.
    • (1998) Med Hypotheses , vol.51 , pp. 405-409
    • Kong, Q.1    Lillehei, K.O.2
  • 42
    • 67650071137 scopus 로고    scopus 로고
    • Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach?
    • Trachootham D, Alexandre J, Huang P. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat Rev Drug Discov 2009;8:579-91.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 579-591
    • Trachootham, D.1    Alexandre, J.2    Huang, P.3
  • 43
    • 0028125095 scopus 로고
    • Protective role of manganese superoxide dismutase against cigarette smoke-induced cytotoxicity
    • St Clair DK, Jordan JA, Wan XS, Gairola CG. Protective role of manganese superoxide dismutase against cigarette smoke-induced cytotoxicity. J Toxicol Environ Health 1994;43:239-49.
    • (1994) J Toxicol Environ Health , vol.43 , pp. 239-249
    • St Clair, D.K.1    Jordan, J.A.2    Wan, X.S.3    Gairola, C.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.