C-Phycocyanin inhibits MDR1 through reactive oxygen species and cyclooxygenase-2 mediated pathways in human hepatocellular carcinoma cell line

European Journal of Pharmacology

Volumn 649, Issue 1-3, 2010, Pages 74-83

  Nishanth, Reddy P ^a,b   Ramakrishna, B S ^a,b   Jyotsna, Radhika G ^a   Roy, Karnati R ^a   Reddy, Gorla V ^a   Reddy, Pratap K ^b   Reddanna, Pallu ^a  

^a UNIVERSITY OF HYDERABAD   (India)

^b OSMANIA UNIVERSITY   (India)

Author keywords

C Phycocyanin; Cyclooxygenase 2; HepG2 cell; MDR1 multidrug resistance 1 ; Reactive oxygen species

Indexed keywords

C PHYCOCYANIN; CYCLOOXYGENASE 2; DOXORUBICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MULTIDRUG RESISTANCE PROTEIN 1; PHYCOCYANIN; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ARTICLE; CARCINOMA CELL; CELL PROLIFERATION; CHEMOSENSITIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION;

ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; CYCLOOXYGENASE 2; DINOPROSTONE; DOWN-REGULATION; DOXORUBICIN; DRUG SYNERGISM; ENZYME INHIBITORS; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; NADPH OXIDASE; P-GLYCOPROTEIN; PHYCOCYANIN; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 78049231394     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.09.011     Document Type: Article

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