-
1
-
-
1942485807
-
Sigma-1receptor ligands: Potential in the treatment of neuropsychiatric disorders
-
Hayashi T, Su TP. Sigma-1receptor ligands: Potential in the treatment of neuropsychiatric disorders. CNS Drugs 2004; 18: 269-284
-
(2004)
CNS Drugs
, vol.18
, pp. 269-284
-
-
Hayashi, T.1
Su, T.P.2
-
2
-
-
26844474972
-
Sigma-1 receptors: Evolution of the concept in neuropsychopharmacology
-
Hayashi T, Su TP. Sigma-1 receptors: Evolution of the concept in neuropsychopharmacology. Curr Neuropharmacol 2005; 3: 267-280
-
(2005)
Curr Neuropharmacol
, vol.3
, pp. 267-280
-
-
Hayashi, T.1
Su, T.P.2
-
3
-
-
0034085467
-
Ca2+ signaling via sigma-1 receptors: Novel regulatory mechanism affecting intracellular Ca2+concentration
-
Hayashi T, Maurice T, Su TP. Ca2+ signaling via sigma-1 receptors: Novel regulatory mechanism affecting intracellular Ca2+concentration. J Pharmacol Exp Ther 2000; 293: 788-798
-
(2000)
J Pharmacol Exp Ther
, vol.293
, pp. 788-798
-
-
Hayashi, T.1
Maurice, T.2
Su, T.P.3
-
4
-
-
0035895206
-
Regulating ankyrin dynamics: Roles of sigma-1 receptors
-
Hayashi T, Su TP. Regulating ankyrin dynamics: Roles of sigma-1 receptors. Proc Natl Acad Sci USA 2001; 98: 491-496
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 491-496
-
-
Hayashi, T.1
Su, T.P.2
-
5
-
-
0026031867
-
Selective loss of cerebral cortical sigma, but not PCP binding sites in schizophrenia
-
Weissman AD, Casanova MF, Kleinman JE, London ED, De Souza EB. Selective loss of cerebral cortical sigma, but not PCP binding sites in schizophrenia. Biol Psychiatry 1991; 29: 41-54
-
(1991)
Biol Psychiatry
, vol.29
, pp. 41-54
-
-
Weissman, A.D.1
Casanova, M.F.2
Kleinman, J.E.3
London, E.D.4
De Souza, E.B.5
-
6
-
-
59649121472
-
Sigma-1 receptor knockout mice display a depressive-Like phenotype
-
Sabino V, Cottone P, Parylak SL, Steardo L, Zorrilla EP. Sigma-1 receptor knockout mice display a depressive-Like phenotype. Behav Brain Res 2009; 198: 472-476
-
(2009)
Behav Brain Res
, vol.198
, pp. 472-476
-
-
Sabino, V.1
Cottone, P.2
Parylak, S.L.3
Steardo, L.4
Zorrilla, E.P.5
-
7
-
-
26844474972
-
The sigma receptor: Evolution of the concept in neuropsychopharmacology
-
Hayashi T, Su TP. The sigma receptor: Evolution of the concept in neuropsychopharmacology. Curr Neuropharmacol 2005; 3: 267-280
-
(2005)
Curr Neuropharmacol
, vol.3
, pp. 267-280
-
-
Hayashi, T.1
Su, T.P.2
-
8
-
-
79954498271
-
Targeting ligand-Operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders
-
Hayashi T, Tsai SY, Mori T, Fujimoto M, Su TP. Targeting ligand-Operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders. Expert Opin Ther Targets 2011; 15: 557-577
-
(2011)
Expert Opin Ther Targets
, vol.15
, pp. 557-577
-
-
Hayashi, T.1
Tsai, S.Y.2
Mori, T.3
Fujimoto, M.4
Su, T.P.5
-
9
-
-
82355190062
-
Sigma-1Rs are upregulated via PERK/eIF2alpha/ATF4 pathway and execute protective function in ER stress
-
Mitsuda T, Omi T, Tanimukai H, Sakagami Y, Kudo T, Takeda M. Sigma-1Rs are upregulated via PERK/eIF2alpha/ATF4 pathway and execute protective function in ER stress. Biochem Biophys Res Commun 2011; 415: 519-525
-
(2011)
Biochem Biophys Res Commun
, vol.415
, pp. 519-525
-
-
Mitsuda, T.1
Omi, T.2
Tanimukai, H.3
Sakagami, Y.4
Kudo, T.5
Takeda, M.6
-
10
-
-
0030594575
-
Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain
-
Narita N, Hashimoto K, Tomitaka S, Minabe Y. Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain. Eur J Pharmacol 1996; 307: 117-119
-
(1996)
Eur J Pharmacol
, vol.307
, pp. 117-119
-
-
Narita, N.1
Hashimoto, K.2
Tomitaka, S.3
Minabe, Y.4
-
11
-
-
0032101239
-
The unfolded protein response: An intracellular signaling pathway with many surprising features
-
Sidrauski C, Chapman R, Walter P. The unfolded protein response: An intracellular signaling pathway with many surprising features. Trends Cell Biol 1998; 8: 245-249
-
(1998)
Trends Cell Biol
, vol.8
, pp. 245-249
-
-
Sidrauski, C.1
Chapman, R.2
Walter, P.3
-
12
-
-
5444264022
-
Translation reinitiation at alternative open readingframes regulates gene expression in an integrated stress response
-
Lu PD, Harding HP, Ron D. Translation reinitiation at alternative open readingframes regulates gene expression in an integrated stress response. J Cell Biol 2004; 167: 27-33
-
(2004)
J Cell Biol
, vol.167
, pp. 27-33
-
-
Lu, P.D.1
Harding, H.P.2
Ron, D.3
-
13
-
-
3843117589
-
Reinitiation involving upstream ORFs regulates ATF4mRNA translation in mammalian cells
-
Vattem KM, Wek RC. Reinitiation involving upstream ORFs regulates ATF4mRNA translation in mammalian cells. Proc Natl Acad Sci USA 2004; 101: 11269-11274
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 11269-11274
-
-
Vattem, K.M.1
Wek, R.C.2
-
14
-
-
4744344331
-
Cerebral ischemia and the unfolded protein response
-
DeGracia DJ, Montie HL. Cerebral ischemia and the unfolded protein response. J Clin Invest 2004; 91: 1-8
-
(2004)
J Clin Invest
, vol.91
, pp. 1-8
-
-
Degracia, D.J.1
Montie, H.L.2
-
15
-
-
0029976959
-
Reduced brainedema and infarction volume in mice lacking the neuronal isoform ofnitric oxide synthase after transient MCA occlusion
-
Hara H, Huang PL, Panahian N, Fishman MC, Moskowitz MA. Reduced brainedema and infarction volume in mice lacking the neuronal isoform ofnitric oxide synthase after transient MCA occlusion. J Cereb Blood Flow Metab 1996; 16: 605-611
-
(1996)
J Cereb Blood Flow Metab
, vol.16
, pp. 605-611
-
-
Hara, H.1
Huang, P.L.2
Panahian, N.3
Fishman, M.C.4
Moskowitz, M.A.5
-
16
-
-
0030614952
-
Inhibition of interleukin 1b converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage
-
Hara H, Friedlander RM, Gagliardini V, Ayata C, Fink K, Moskowitz MA et al. Inhibition of interleukin 1b converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage. Proc. Natl Acad Sci USA 1997; 94: 2007-2012
-
(1997)
Proc. Natl Acad Sci USA
, vol.94
, pp. 2007-2012
-
-
Hara, H.1
Friedlander, R.M.2
Gagliardini, V.3
Ayata, C.4
Fink, K.5
Moskowitz, M.A.6
-
17
-
-
2442432416
-
Involvement of caspase-4 in endoplasmic reticulum stress-Induced apoptosis and A b-induced cell death
-
Hitomi J, Katayama T, Eguchi Y, Kudo T, Taniguchi M, Imaizumi K et al. Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and A b-induced cell death. J Cell Biol 2004; 165: 347-356
-
(2004)
J Cell Biol
, vol.165
, pp. 347-356
-
-
Hitomi, J.1
Katayama, T.2
Eguchi, Y.3
Kudo, T.4
Taniguchi, M.5
Imaizumi, K.6
-
18
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-Beta
-
Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yuan J et al. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 2000; 403: 98-103
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yuan, J.6
-
19
-
-
0036606540
-
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
-
Nishitoh H, Matsuzawa A, Tobiume K, Saegusa K, Takeda K, Ichijo H et al. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev 2002; 16: 1345-1355
-
(2002)
Genes Dev
, vol.16
, pp. 1345-1355
-
-
Nishitoh, H.1
Matsuzawa, A.2
Tobiume, K.3
Saegusa, K.4
Takeda, K.5
Ichijo, H.6
-
20
-
-
38049170584
-
A molecular chaper one inducer protects neurons from ER stress
-
Kudo T, Kanemoto S, Hara H, Morimoto N, Imaizumi K, Takeda M et al. A molecular chaper one inducer protects neurons from ER stress. Cell Death Differ 2008; 15: 364-375
-
(2008)
Cell Death Differ
, vol.15
, pp. 364-375
-
-
Kudo, T.1
Kanemoto, S.2
Hara, H.3
Morimoto, N.4
Imaizumi, K.5
Takeda, M.6
-
21
-
-
0032557657
-
Regulation of Guanine Nucleotide Exchange through Phosphorylation of Eukaryotic Initiation Factor eIF2: ROLE of the a-and d-SUBUNITS of eIF2B
-
Kimball SR, Fabian JR, Pavitt GD, Hinnebusch AG, Jefferson LS. Regulation of Guanine Nucleotide Exchange through Phosphorylation of Eukaryotic Initiation Factor eIF2: ROLE OF THE a-and d-SUBUNITS OF eIF2B. J Biol Chem 1998; 272: 21661-21664
-
(1998)
J Biol Chem
, vol.272
, pp. 21661-21664
-
-
Kimball, S.R.1
Fabian, J.R.2
Pavitt, G.D.3
Hinnebusch, A.G.4
Jefferson, L.S.5
-
22
-
-
0032553577
-
Association between polymorphisms in the type 1 sigma receptor gene and schizophrenia
-
Ishiguro H, Ohtsuki T, Toru M, Itokawa M, Aoki J, Arinami T et al. Association between polymorphisms in the type 1 sigma receptor gene and schizophrenia. Neurosci Lett 1998; 257: 45-46
-
(1998)
Neurosci Lett
, vol.257
, pp. 45-46
-
-
Ishiguro, H.1
Ohtsuki, T.2
Toru, M.3
Itokawa, M.4
Aoki, J.5
Arinami, T.6
-
23
-
-
51449086380
-
Associations of ATF4 gene polymorphisms with schizophrenia in male patients
-
Qu M, Tang F, Wang L, Yan H, Han Y, Zhang D et al. Associations of ATF4 gene polymorphisms with schizophrenia in male patients. Am J Med Genet B Neuropsychiatr Genet 2008; 147B: 732-736
-
(2008)
Am J Med Genet B Neuropsychiatr Genet
, vol.147 B
, pp. 732-736
-
-
Qu, M.1
Tang, F.2
Wang, L.3
Yan, H.4
Han, Y.5
Zhang, D.6
-
24
-
-
84865860589
-
A randomized, doubleblind, placebo-controlled trial of fluvoxamine in patients with schizophrenia: A preliminary study
-
Niitsu T, Fujisaki M, Shiina A, Yoshida T, Hasegawa T, Iyo M et al. A randomized, doubleblind, placebo-controlled trial of fluvoxamine in patients with schizophrenia: A preliminary study. J Clin Psychopharmacol 2012; 32: 593-601
-
(2012)
J Clin Psychopharmacol
, vol.32
, pp. 593-601
-
-
Niitsu, T.1
Fujisaki, M.2
Shiina, A.3
Yoshida, T.4
Hasegawa, T.5
Iyo, M.6
-
25
-
-
0036894824
-
Nerve growth factor-Induced neurite sprouting in PC12 cells involved s-1 receptors: Implications for antidepressants
-
Takebayashi M, Hayashi T, Su TP. Nerve growth factor-induced neurite sprouting in PC12 cells involved s-1 receptors: Implications for antidepressants. J Pharmacol Exp Ther 2002; 303: 1227-1237
-
(2002)
J Pharmacol Exp Ther
, vol.303
, pp. 1227-1237
-
-
Takebayashi, M.1
Hayashi, T.2
Su, T.P.3
-
26
-
-
36348930605
-
The role of brainderived neurotrophic factor (BDNF)-Induced XBP1 splicing during brain development
-
Hayashi A, Kasahara T, Iwamoto K, Ishiwata M, Kametani M, Kato T et al. The role of brainderived neurotrophic factor (BDNF)-Induced XBP1 splicing during brain development. J Biol Chem 2007; 282: 34525-34534
-
(2007)
J Biol Chem
, vol.282
, pp. 34525-34534
-
-
Hayashi, A.1
Kasahara, T.2
Iwamoto, K.3
Ishiwata, M.4
Kametani, M.5
Kato, T.6
-
28
-
-
0035872446
-
Regulation of tumor angiogenesis by oxygen-Regulated protein 150, an inducible endoplasmic reticulum chaperone
-
Ozawa K, Tsukamoto Y, Hori O, Kitao Y, Yanagi H, Ogawa S et al. Regulation of tumor angiogenesis by oxygen-regulated protein 150, an inducible endoplasmic reticulum chaperone. Cancer Res 2001; 61: 4206-4213
-
(2001)
Cancer Res
, vol.61
, pp. 4206-4213
-
-
Ozawa, K.1
Tsukamoto, Y.2
Hori, O.3
Kitao, Y.4
Yanagi, H.5
Ogawa, S.6
-
29
-
-
33745019669
-
Endoplasmic reticulum stress gene induction and protection fromischemia/reperfusion injury in the hearts of transgenic mice with a tamoxifen-Regulated form of ATF6
-
Martindale JJ, Fernandez R, Thuerauf D, Whittaker R, Gude N, Glembotski CC et al. Endoplasmic reticulum stress gene induction and protection fromischemia/reperfusion injury in the hearts of transgenic mice with a tamoxifen-regulated form of ATF6. Circ Res 2006; 98: 1186-1193
-
(2006)
Circ Res
, vol.98
, pp. 1186-1193
-
-
Martindale, J.J.1
Fernandez, R.2
Thuerauf, D.3
Whittaker, R.4
Gude, N.5
Glembotski, C.C.6
-
30
-
-
0036345454
-
CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity
-
Imai Y, Soda M, Hatakeyama S, Akagi T, Hashikawa T, Takahashi R et al. CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. Mol Cell 2002; 10: 55-67
-
(2002)
Mol Cell
, vol.10
, pp. 55-67
-
-
Imai, Y.1
Soda, M.2
Hatakeyama, S.3
Akagi, T.4
Hashikawa, T.5
Takahashi, R.6
-
31
-
-
0033258544
-
Presenilin-1 mutations downregulate the signaling pathway of the unfolded-Protein response
-
Katayama T, Imaizumi K, Sato N, Miyoshi K, Kudo T, Tohyama M et al. Presenilin-1 mutations downregulate the signaling pathway of the unfolded-protein response. Nat Cell Biol 1999; 8: 479-485
-
(1999)
Nat Cell Biol
, vol.8
, pp. 479-485
-
-
Katayama, T.1
Imaizumi, K.2
Sato, N.3
Miyoshi, K.4
Kudo, T.5
Tohyama, M.6
-
32
-
-
0035900779
-
Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's diseaselinked presenilin 1 mutations
-
Katayama T, Imaizumi K, Honda A, Yoneda T, Kudo T, Tohyama M,A et al. Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's diseaselinked presenilin 1 mutations. J Biol Chem 2001; 276: 43446-43454
-
(2001)
J Biol Chem
, vol.276
, pp. 43446-43454
-
-
Katayama, T.1
Imaizumi, K.2
Honda, A.3
Yoneda, T.4
Kudo, T.5
Tohyama, M.A.6
-
33
-
-
33751411962
-
A feasibility study of [11C] SA4503-PET for evaluating sigma-1 receptor occupancy by neuroleptics: The binding of haloperidol to sigma-1 and dopamine D2-Like receptors
-
Ishiwata K, Oda K, Sakata M, Kimura Y, Kawamura K, Ishii K et al. A feasibility study of [11C]SA4503-PET for evaluating sigma-1 receptor occupancy by neuroleptics: the binding of haloperidol to sigma-1 and dopamine D2-Like receptors. Ann Nucl Med 2006; 20: 569-573
-
(2006)
Ann Nucl Med
, vol.20
, pp. 569-573
-
-
Ishiwata, K.1
Oda, K.2
Sakata, M.3
Kimura, Y.4
Kawamura, K.5
Ishii, K.6
-
34
-
-
33845311194
-
ATF4 regulates gamma-Secretase activity during amino acid imbalance
-
Mitsuda T, Hayakawa Y, Itoh M, Ohta K, Nakagawa T. ATF4 regulates gamma-Secretase activity during amino acid imbalance. Biochem Biophys. Res Commun 2007; 352: 722-727
-
(2007)
Biochem Biophys. Res Commun
, vol.352
, pp. 722-727
-
-
Mitsuda, T.1
Hayakawa, Y.2
Itoh, M.3
Ohta, K.4
Nakagawa, T.5
|