Differential expression of tripartite motif-containing family in normal human dermal fibroblasts in response to porcine endogenous retrovirus infection

Folia Biologica (Czech Republic)

Volumn 60, Issue 3, 2014, Pages 144-151

  Kimsa, M W ^a   Strzalka Mrozik, B ^a   Kimsa, M C ^a   Mazurek, U ^a   Kruszniewska Rajs, C ^a   Gola, J ^a   Adamska, J ^a   Twardoch, M ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

Lipopolysaccharide; Oligonucleotide microarray; Porcine endogenous retrovirus; Tripartite motif containing family; Xenotransplantation

Indexed keywords

LIPOPOLYSACCHARIDE; CARRIER PROTEIN; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CELL COUNT; CONTROLLED STUDY; DOWN REGULATION; ENDOGENOUS RETROVIRUS; EPITHELIUM CELL; FIBROBLAST; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; NONHUMAN; PROTEIN FAMILY; PROTEIN MOTIF; RETROVIRUS INFECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN CELL; TRIM GENE; TRIM1 GENE; TRIM16 GENE; TRIM18 GENE; TRIM2 GENE; TRIM22 GENE; TRIM27 GENE; TRIM31 GENE; TRIM4 GENE; TRIM5 GENE; UPREGULATION; VIRUS CELL INTERACTION; XENOTRANSPLANTATION; ANIMAL; DERMIS; DNA MICROARRAY; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; REPRODUCIBILITY; SWINE; VIROLOGY;

AMINO ACID MOTIFS; ANIMALS; CARRIER PROTEINS; DERMIS; ENDOGENOUS RETROVIRUSES; FIBROBLASTS; GENE EXPRESSION PROFILING; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUS SCROFA;

EID: 84905508599     PISSN: 00155500     EISSN: 25337602     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Abudu, A., Takaori-Kondo, A., Izumi, T., Shirakawa, K., Kobayashi, M., Sasada, A., Fukunaga, K., Uchiyama, T. (2006) Murine retrovirus escapes from murine APOBEC3 via two distinct novel mechanisms. Curr. Biol. 16, 1565-1570.
2. Asaoka, K., Ikeda, K., Hishinuma, T., Horie-Inoue, K., Takeda, S., Inoue, S. (2005) A retrovirus restriction factor TRIM5α is transcriptionally regulated by interferons. Biochem. Biophys. Res. Commun. 338, 1950-1956.
3. Barr, S. D., Smiley, J. R., Bushman, F. D. (2008) The interferon response inhibits HIV particle production by induction of TRIM22. PLoS Pathog. 4, e1000007.
4. Bell, J. L., Malyukova, A., Holien, J. K., Koach, J., Parker, M. W., Kavallaris, M., Marshall, G. M., Cheung, B. B. (2012) TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members. PLoS One 7, e37470.
5. Bouazzaoui, A., Kreutz, M., Eisert, V., Dinauer, N., Heinzelmann, A., Hallenberger, S., Strayle, J., Walker, R., Rübsamen-Waigmann, H., Andreesen, R., von Briesen, H. (2006) Stimulated trans-acting factor of 50 kDa (Staf50) inhibits HIV-1 replication in human monocyte-derived macrophages. Virology 356, 79-94.
6. Boulware, D. R., Meya, D. B., Bergemann, T. L., Williams, D., Vlasova-St Louis, I. A., Rhein, J., Staddon, J., Kambugu, A., Janoff, E. N., Bohjanen, P. R. (2010) Antiretroviral therapy down-regulates innate antiviral response genes in patients with AIDS in sub-Saharan Africa. J. Acquir. Immune Defic. Syndr. 55, 428-438.
7. Brenchley, J. M., Price, D. A., Schacker, T. W., Asher, T. E., Silvestri, G., Rao, S., Kazzaz, Z., Bornstein, E., Lambotte, O., Altmann, D., Blazar, B. R., Rodriguez, B., Teixeira-Johnson, L., Landay, A., Martin, J. N., Hecht, F. M., Picker, L. J., Lederman, M. M., Deeks, S. G., Douek, D. C. (2006) Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat. Med. 12, 1365-1371.
8. Carthagena, L., Parise, M. C., Ringeard, M., Chelbi-Alix, M. K., Hazan, U., Nisole, S. (2008) Implication of TRIMα and TRIMCyp in interferon-induced anti-retroviral restriction activities. Retrovirology 5, 59.
9. Carthagena, L., Bergamaschi, A., Luna, J. M., David, A., Uchil, P. D., Margottin-Goguet, F., Mothes, W., Hazan, U., Transy, C., Pancino, G., Nisole, S. (2009) Human TRIM gene expression in response to interferons. PLoS One 4, e4894.
10. Cyganek-Niemiec, A., Strzalka-Mrozik, B., Pawlus-Lachecka, L., Wszolek, J., Adamska, J., Kudrjavtseva, J., Zhuravleva, I., Kimsa, M., Okla, H., Kimsa, M., Gudek, A., Mazurek, U. (2012) Degradation effect of diepoxide fixation on porcine endogenous retrovirus DNA in heart valves: molecular aspects. Int. J. Artif. Organs 35, 25-33.
11. Delebecque, F., Suspene, R., Calattini, S., Casartelli, N., Saib, A., Froment, A., Wain-Hobson, S., Gessain, A., Vartanian, J. P., Schwartz, O. (2006) Restriction of foamy viruses by APOBEC cytidine deaminases. J. Virol. 80, 605-614.
12. Denner, J. (2008) Recombinant porcine endogenous retroviruses (PERV-A/C): a new risk for xenotransplantation? Arch. Virol. 153, 1421-1426.
13. Denner, J., Tönjes, R. R. (2012) Infection barriers to successful xenotransplantation focusing on porcine endogenous retroviruses. Clin. Microbiol. Rev. 25, 318-343.
14. Diaz-Griffero, F., Li, X., Javanbakht, H., Song, B., Welikala, S., Stremlau, M., Sodroski, J. (2006) Rapid turnover and polyubiquitylation of the retroviral restriction factor TRIM5. Virology 349, 300-315.
15. Dieckhoff, B., Petersen, B., Kues, W. A., Kurth, R., Niemann, H., Denner, J. (2008) Knockdown of porcine endogenous retrovirus (PERV) expression by PERV-specific shRNA in transgenic pigs. Xenotransplantation 15, 36-45.
16. Dorrschuck, E., Munk, C., Tonjes, R. R. (2008) APOBEC3 proteins and porcine endogenous retroviruses. Transplant. Proc. 40, 959-961.
17. Doyle, S., Vaidya, S., O'Connell, R., Dadgostar, H., Dempsey, P., Wu, T., Rao, G., Sun, R., Haberland, M., Modlin, R., Cheng, G. (2002) IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity 17, 251-263.
18. Geiss, G. K., Salvatore, M., Tumpey, T. M., Carter, V. S., Wang, X., Basler, C. F., Taubenberger, J. K., Bumgarner, R. E., Palese, P., Katze, M. G., García-Sastre, A. (2002) Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza. Proc. Natl. Acad. Sci. USA 99, 10736-10741.
19. Jónsson, S. R., LaRue, R. S., Stenglein, M. D., Fahrenkrug, S. C., Andrésdóttir, V., Harris, R. S. (2007) The restriction of zoonotic PERV transmission by human APOBEC3G. PLoS One 2, e893.
20. Kaiser, S. M., Malik, H. S., Emerman, M. (2007) Restriction of an extinct retrovirus by the human TRIM5α antiviral protein. Science 316, 1756-1758.
21. Kedzierska, K., Crowe, S. M., Turville, S., Cunningham, A. L. (2003) The influence of cytokines, chemokines and their receptors on HIV-1 replication in monocytes and macrophages. Rev. Med. Virol. 13, 39-56.
22. Kimsa, M. C., Strzalka-Mrozik, B., Kimsa, M. W., Kruszniewska-Rajs, C., Gola, J., Adamska, J., Rajs, A., Mazurek, U. (2013) Porcine endogenous retrovirus infection changes the expression of inflammation-related genes in lipopolysaccharide-stimulated human dermal fibroblasts. Ann. Transplant. 18, 576-586.
23. Kornbluth, R. S., Oh, P. S., Munis, J. R., Cleveland, P. H., Richman, D. D. (1989) Interferons and bacterial lipopolysaccharide protect macrophages from productive infection by human immunodeficiency virus in vitro. J. Exp. Med. 169, 1137-11351.
24. Laguette, N., Benkirane, M. (2012) How SAMHD1 changes our view of viral restriction. Trends Immunol. 33, 26-33.
25. Lee, D., Lee, J., Park, N., Oh, Y. K., Kwon, M., Kim, Y. B. (2008) Analysis of natural recombination in porcine endogenous retrovirus envelope genes. J. Microbiol. Biotechnol. 18, 585-590.
26. Lee, J., Cho, Y. D., Heo, Y. K., Kwon, Y., Kim, D. G., Choi, B. S., Kim, S. S., Kim, Y. B. (2011a) Reduction of N-tropic mutant porcine endogenous retrovirus infectivity by human tripartite motif-containing 5-isoform α. Transplant. Proc. 43, 2774-2778.
27. Lee, J., Choi, J. Y., Lee, H. J., Kim, K. C., Choi, B. S., Oh, Y. K., Kim, Y. B. (2011b) Repression of porcine endogenous retrovirus infection by human APOBEC3 proteins. Biochem. Biophys. Res. Commun. 407, 266-270.
28. Li, Z., Ping, Y., Shengfu, L., Yangzhi, Z., Jingqiu, C., Youping, L., Hong, B. (2006) Variation of host cell tropism of porcine endogenous retroviruses expressed in Chinese Banna minipig inbred. Intervirology 49, 185-191.
29. Lu, Y. C., Yeh, W. C., Ohashi, P. S. (2008) LPS/TLR4 signal transduction pathway. Cytokine 42, 145-151.
30. Martinez, F. O., Gordon, S., Locati, M., Mantovani, A. (2006) Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J. Immunol. 177, 7303-7311.
31. Meije, Y., Tönjes, R. R., Fishman, J. A. (2010) Retroviral restriction factors and infectious risk in xenotransplantation. Am. J. Transplant. 10, 1511-1516.
32. Mous, K., Jennes, W., Camara, M., Seydi, M., Daneau, G., Mboup, S., Kestens, L., Van Ostade, X. (2012) Expression analysis of LEDGF/p75, APOBEC3G, TRIM5α, and tetherin in a Senegalese cohort of HIV-1-exposed seronegative individuals. PLoS One 7, e33934.
33. Nisole, S., Stoye, J. P., Saïb, A. (2005) TRIM family proteins: retroviral restriction and antiviral defence. Nat. Rev. Microbiol. 3, 799-808.
34. Perez-Caballero, D., Soll, S. J., Bieniasz, P. D. (2008) Evidence for restriction of ancient primate gammaretroviruses by APOBEC3 but not TRIM5α proteins. PLoS Pathog. 4, e1000181.
35. Pertel, T., Hausmann, S., Morger, D., Züger, S., Guerra, J., Lascano, J., Reinhard, C., Santoni, F. A., Uchil, P. D., Chatel, L., Bisiaux, A., Albert, M. L., Strambio-De-Castillia, C., Mothes, W., Pizzato, M., Grütter, M. G., Luban, J. (2011) TRIM5 is an innate immune sensor for the retrovirus capsid lattice. Nature 472, 361-365.
36. Pineda, M. J., Orton, B. R., Overbaugh, J. (2007) A TRIM5α- independent post-entry restriction to HIV-1 infection of macaque cells that is dependent on the path of entry. Virology 363, 310-308.
37. Rajsbaum, R., Stoye, J. P., O'Garra, A. (2008) Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells. Eur. J. Immunol. 38, 619-630.
38. Ramsoondar, J., Vaught, T., Ball, S., Mendicino, M., Monahan, J., Jobst, P., Vance, A., Duncan, J., Wells, K., Ayares, D. (2009) Production of transgenic pigs that express porcine endogenous retrovirus small interfering RNAs. Xenotransplantation 16, 164-180.
39. Rold, C. J., Aiken, C. (2008) Proteasomal degradation of TRIM5α during retrovirus restriction. PLoS Pathog. 4, e1000074.
40. Sakuma, R., Mael, A. A., Ikeda, Y. (2007) Alpha interferon enhances TRIM5α-mediated antiviral activities in human and rhesus monkey cells. J. Virol. 81, 10201-10206.
41. Scobie, L., Takeuchi, Y. (2009) Porcine endogenous retrovirus and other viruses in xenotransplantation. Curr. Opin. Organ Transplant. 14, 175-179.
42. Scobie, L., Padler-Karavani, V., Le Bas-Bernardet, S., Crossan, C., Blaha, J., Matouskova, M., Hector, R. D., Cozzi, E., Vanhove, B., Charreau, B., Blancho, G., Bourdais, L., Tallacchini, M., Ribes, J. M., Yu, H., Chen, X., Kracikova, J., Broz, L., Hejnar, J., Vesely, P., Takeuchi, Y., Varki, A., Soulillou, J. P. (2013) Long-term IgG response to porcine Neu5Gc antigens without transmission of PERV in burn patients treated with porcine skin xenografts. J. Immunol. 191, 2907-2915.
43. Semaan, M., Kaulitz, D., Petersen, B., Niemann, H., Denner, J. (2012) Long-term effects of PERV-specific RNA interference in transgenic pigs. Xenotransplantation 19, 112-121.
44. Sewram, S., Singh, R., Kormuth, E., Werner, L., Mlisana, K., Karim, S. S., Ndung'u T., CAPRISA Acute Infection Study Team (2009) Human TRIM5α expression levels and reduced susceptibility to HIV-1 infection. J. Infect. Dis. 199, 1657-1663.
45. Shi, M., Wang, X., De Clercq, E., Takao, S., Baba, M. (2007) Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates. Antimicrob. Agents Chemother. 51, 2600-2604.
46. Simard, S., Maurais, E., Gilbert, C., Tremblay, M. J. (2008) LPS reduces HIV-1 replication in primary human macrophages partly through an endogenous production of type I interferons. Clin. Immunol. 127, 198-205.
47. Specke, V., Tacke, S. J., Boller, K., Schwendemann, J., Denner, J. (2001) Porcine endogenous retroviruses: in vitro host range and attempts to establish small animal models. J. Gen. Virol. 82, 837-844.
48. Strzalka-Mrozik, B., Stanik-Walentek, A., Kapral, M., Kowalczyk, M., Adamska, J., Gola, J., Mazurek, U. (2010) Differential expression of transforming growth factor-β isoforms in bullous keratopathy corneas. Mol. Vis. 16, 161-166.
49. Tissot, C., Mechti, N. (1995) Molecular cloning of a new interferon induced factor that represses human immunodeficiency virus type 1 long terminal repeat expression. J. Biol. Chem. 270, 14891-14898.
50. Uchil, P. D., Quinlan, B. D., Chan, W. T., Luna, J. M., Mothes, W. (2008) TRIM E3 ligases interfere with early and late stages of the retroviral life cycle. PLoS Pathog. 4, e16.
51. Uchil, P. D., Hinz, A., Siegel, S., Coenen-Stass, A., Pertel, T., Luban, J., Mothes, W. (2013) TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity. J. Virol. 87, 257-272.
52. Uematsu, S., Akira, S. (2007) Toll-like receptors and type I interferons. J. Biol. Chem. 282, 15319-15323.
53. Wang, H., Garcia, C. A., Rehani, K., Cekic, C., Alard, P., Kinane, D. F., Mitchell, T., Martin, M. (2008) IFN-β production by TLR4-stimulated innate immune cells is negatively regulated by GSK3-β. J. Immunol. 181, 6797-6802.
54. Wood, A., Webb, B. L., Bartosch, B., Schaller, T., Takeuchi, Y., Towers, G. J. (2009) Porcine endogenous retroviruses PERV A and A/C recombinant are insensitive to a range of divergent mammalian TRIM5α proteins including human TRIM5α. J. Gen. Virol. 90, 702-709.
55. Yap, M. W., Nisole, S., Lynch, C., Stoye, J. P. (2004) Trim5α protein restricts both HIV-1 and murine leukemia virus. Proc. Natl. Acad. Sci. USA 101, 10786-10791.