Recombinant porcine endogenous retroviruses (PERV-A/C): A new risk for xenotransplantation?

Archives of Virology

Volumn 153, Issue 8, 2008, Pages 1421-1426

  Denner, Joachim ^a  

^a ROBERT KOCH INSTITUTE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ENDOGENOUS RETROVIRUS; GENETICS; GERM CELL; HUMAN; METABOLISM; PATHOGENICITY; PHYSIOLOGY; PROVIRUS; SHORT SURVEY; SWINE DISEASE; VIROLOGY; VIRUS REPLICATION; XENOGRAFT;

ANIMALS; ENDOGENOUS RETROVIRUSES; GERM CELLS; HUMANS; PROVIRUSES; SWINE DISEASES; TRANSPLANTATION, HETEROLOGOUS; VIRUS REPLICATION;

PORCINE ENDOGENOUS RETROVIRUS; SUIDAE;

EID: 47549090956     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00705-008-0141-7     Document Type: Short Survey

References (63)

1. Sachs DH, Sykes M, Robson SC, Cooper DK (2001) Xenotransplantation. Adv Immunol 79:129-223
2. Tucker A, Belcher C, Moloo B, Bell J, Mazzulli T, Humar A, Hughes A, McArdle P, Talbot A (2002) The production of transgenic pigs for potential use in clinical xenotransplantation: microbiological evaluation. Xenotransplantation 9:191-202
3. Denner J (1998) Immunosuppression by retroviruses: implications for xenotransplantation. Ann NY Acad Sci 862:75-86
4. Denner J (2007) Transspecies transmissions of retroviruses: new cases. Virology 369:229-233
5. Le Tissier P, Stoye JP, Takeuchi Y, Patience C, Weiss RA (1997) Two sets of human-tropic pig retrovirus. Nature 389:681-682
6. Patience C, Switzer WM, Takeuchi Y, Griffiths DJ, Goward ME, Heneine W, Stoye JP, Weiss RA (2001) Multiple groups of novel retroviral genomes in pigs and related species. J Virol 75:2771-2775
7. Ericsson T, Oldmixon B, Blomberg J, Rosa M, Patience C, Andersson G (2001) Identification of novel porcine endogenous betaretrovirus sequences in miniature swine. J Virol 75:2765-2770
8. Mang R, Maas J, Chen X, Goudsmit J, van der Kuyl AC (2001) Identification of novel type C porcine endogenous retrovirus: evidence that copy number of endogenous retrovirus increases during host inbreeding. J Gen Virol 82:1829-1834
9. Wilson CA, Wong S, Muller J, Davidson CE, Rose TM, Burd P (1998) Type C retrovirus released from porcine primary peripheral blood mononuclear cells infects human cells. J Virol 72:3082-3087
10. Wilson CA, Wong S, Van Brocklin M, Federspiel MJ (2000) Extended analysis of the in vitro tropism of porcine endogenous retrovirus. J Virol 74:49-56
11. Martin U, Kiessig V, Blusch JH, Haverich A, Von der Helm K, Herden T, Steinhoff G (1998) Expression of pig endogenous retrovirus by primary porcine endothelial cells and infection of human cells. Lancet 352:692-694
12. Tacke SJ, Specke V, Denner J (2003) Differences in release and determination of subtype of porcine endogenous retroviruses produced by stimulated normal pig blood cells. Intervirology 46:17-24
13. Tacke SJ, Kurth R, Denner J (2000) Porcine endogenous retroviruses inhibit human immune cell function: risk for xenotransplantation? Virology 268:87-93
14. McIntyre MC, Kannan B, Solano-Aguilar GI, Wilson CA, Bloom ET (2003) Detection of porcine endogenous retrovirus in cultures of freshly isolated porcine bone marrow cells. Xenotransplantation 10:337-342
15. Dieckhoff B, Puhlmann J, Büscher K, Hafner-Marx A, Herbach N, Bannert N, Büttner M, Wanke R, Kurth R, Denner J (2007) Expression of porcine endogenous retroviruses PERVs in melanomas of Munich miniature swine MMS troll. Vet Microbiol 123:53-68
16. Suzuka I, Shimizu N, Sekiguchi K, Hoshino H, Kodama M, Shimotohno K (1986) Molecular cloning of unintegrated closed circular DNA of porcine retrovirus. FEBS Lett 198:339-343
17. Moennig V, Frank H, Hunsmann G, Ohms P, Schwarz H, Schäfer W (1974) C-type particles produced by a permanent cell line from a leukemic pig. II. Physical, chemical and serological characterization of the particles. Virology 57:179-188
18. Frazier ME (1985) Evidence for retrovirus in miniature swine with radiation-induced leukemia or metaplasia. Arch Virol 83:83-97
19. Patience C, Takeuchi Y, Weiss WA (1997) Infection of human cells by an endogenous retrovirus of pigs. Nat Med 3:282-286
20. Martin U, Winkler ME, Id M, Radeke H, Arseniev L, Takeuchi Y, Simon AR, Patience C, Haverich A, Steinhoff G (2000) Productive infection of primary human endothelial cells by pig endogenous retrovirus (PERV). Xenotransplantation 7:138-142
21. Specke V, Rubant S, Denner J (2001) Productive infection of human primary cells and cell lines with porcine endogenous retroviruses. Virology 285:177-180
22. Takeuchi Y, Patience C, Magre S, Weiss RA, Banerjee PT, Le Tissier P, Stoye JP (1998) Infection of human cells by an endogenous retrovirus of pigs. J Virol 72:9986-9991
23. Specke V, Boller K, Schwendemann J, Denner J (2001) Porcine endogenous retroviruses (PERVs): In vitro host range and attempts to establish small animal models. J Gen Virol 82:837-844
24. Specke V, Schuurman HJ, Plesker R, Coulibaly C, Özel M, Langford G, Kurth R, Denner J (2002) Virus safety in xenotransplantation: preliminary data from first small animal and non-human primate in vivo experiments. Transpl Immunol 9:281-288
25. Specke V, Plesker R, Coulibaly C, Boller K, Denner J (2002) Productive infection of a mink cell line with porcine endogenous retroviruses (PERVs) and lack of transmission to minks in vivo. Arch Virol 147:305-319
26. Blusch JH, Patience C, Takeuchi Y, Templin C, Roos C, Von Der Helm K, Steinhoff G, Martin U (2000) Infection of nonhuman primate cells by pig endogenous retrovirus. J Virol 74:7687-7690
27. Ericsson TA, Takeuchi Y, Templin C, Quinn G, Farhadian SF, Wood JC, Oldmixon BA, Suling KM, Ishii JK, Kitagawa Y, Miyazawa T, Salomon DR, Weiss RA, Patience C (2003) Identification of receptors for pig endogenous retrovirus. Proc Natl Acad Sci 100:6759-6764
28. Mattiuzzo G, Matouskova M, Takeuchi Y (2007) Differential resistance to cell entry by porcine endogenous retrovirus subgroup A in rodent species. Retrovirology 4(1):93
29. Valérie C, Salemi M, Pourrut X, Mpoudi-Ngole E, Abela B, Auzel P, Bibollet-Ruche F, Hahn B, Vandamme AM, Delaporte E, Peeters M (2002) Characterization of a novel simian immunodeficiency virus with a vpu gene from greater spot-nosed monkeys (Cercopithecus nictitans) provides new insights into simian/human immunodeficiency virus phylogeny. J Virol 76:8298-8309
30. Paraskevis D, Lemey P, Salemi M, Suchard M, Van de Peer Y, Vandamme AM (2003) Analysis of the evolutionary relationships of HIV-1 and SIVcpz sequences using bayesian inference: implications for the origin of HIV-1. Mol Biol Evol 20:1986-1996
31. Gao F, Bailes E, Robertson DL, Chen Y, Rodenburg CM, Michael SF, Cummins LB, Arthur LO, Peeters M, Shaw GM, Sharp PM, Hahn BN (1999) Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes. Nature 397:436-441
32. De Leys R, Vanderborght B, van den Haesevelde M, Heyndrickx L, van Geel A, Wauters C, Bernaerts R, Saman E, Nijs P, Willems B (1990) Isolation and partial characterization of an unusual human immunodeficiency retrovirus from two persons of west-central Africa origin. J Virol 64:1207-1216
33. Gürtler LG, Hauser PH, Eberle J, von Brunn A, Knapp S, Zekeng L, Tsaque JM, Kaptue L (1994) A new subtype of human immunodeficiency virus type 1 (MVP-5180) from Cameroon. J Virol 68:1581-1585
34. Simon F, Mauclere P, Roques P, Loussert-Ajaka I, Muller-Trutwin MC, Saragosti S, Georges-Courbot MC, Barré-Sinoussi F, Brun-Vézinet F (1998) Identification of a new human immunodeficiency virus type 1 distinct from group M and group O. Nat Med 4:1032-1037
35. Charneau P, Borman AM, Quillent C, Guetard D, Chamaret S, Cohen J, Rémy G, Montagnier L, Clavel F (1994) Isolation and envelope sequence of a highly divergent HIV-1 isolate: definition of a new HIV-1 group. Virology 205:247-253
36. Vidal N, Peeters M, Mulanga-Kabeya C, Nzilambi N, Robertson D, Ilunga W, Sema H, Tshimanga K, Bongo B, Delaporte E (2000) Unprecedented degree of human immunodeficiency virus type 1 (HIV-1) group M genetic diversity in the Democratic Republic of Congo suggests that the HIV-1 pandemic originated in Central Africa. J Virol 74:10498-10507
37. Murphy E, Korber B, Georges-Courbot MC, You B, Pinter A, Cook D, Kieny MP, Georges A, Mathiot C, Barré-Sinoussi F (1993) Diversity of V3 region sequences of human immunodeficiency viruses type 1 from the central African Republic. AIDS Res Hum Retroviruses 9:997-1006
38. Yang C, Dash B, Hanna SL, Frances HS, Nzilambi N, Colebunders RC, St Louis M, Quinn TC, Folks TM, Lal RB (2001) Predominance of HIV type 1 subtype G among commercial sex workers from Kinshasa, Democratic Republic of Congo. AIDS Res Hum Retroviruses 17:361-36
39. Konings FA, Burda ST, Urbanski MM, Zhong P, Nadas A, Nyambi PN (2006) Human immunodeficiency virus type 1 (HIV-1) circulating recombinant form 02_AG (CRF02_AG) has a higher in vitro replicative capacity than its parental subtypes A and G. J Med Virol 78(5):523-534
40. Motomura K, Chen J, Hu WS (2008) Genetic recombination between human immunodeficiency virus type 1 (HIV-1) and HIV-2, two distinct human lentiviruses. J Virol 82(4):1923-1933 [Epub 2007 Dec 5]
41. Roy-Burman P (1995) Endogenous env elements: partners in generation of pathogenic feline leukemia viruses. Virus Genes 11(2-3):147-161
42. Mendoza R, Anderson MM, Overbaugh J (2006) A putative thiamine transport protein is a receptor for feline leukemia virus subgroup A. J Virol 80:3378-3385
43. Anderson MM, Lauring AS, Robertson S, Dirks C, Overbaugh J (2001) Feline Pit2 functions as a receptor for subgroup B feline leukemia viruses. J Virol 75:10563-10572
44. Takeuchi Y, Vile RG, Simpson G, O'Hara B, Collins MK, Weiss RA (1992) Feline leukemia virus subgroup B uses the same cell surface receptor as gibbon ape leukemia virus. J Virol 66(2):1219-1222
45. Fan H (1997) Leukemogenesis by Moloney murine leukemia virus: a Multistep process. Trends Microbiol 5(2):74-82
46. Villanueva RA, Campbell S, Roth MJ (2003) Molecular analysis of a recombinant M- MuLV/RaLV retrovirus. Virology 315(1):195-208
47. Hu WS, Temin HM (1990) Genetic consequences of packaging two RNA genomes in one retroviral particle: pseudodiploidy and high rate of genetic recombination. Proc Natl Acad Sci USA 87(4):1556-1560
48. Han JY, Cannon PM, Lai KM, Zhao Y, Eiden MV, Anderson WF (1997) Identification of envelope protein residues required for the expanded host range of 10A1 murine leukemia virus. J Virol 71:8103-8108
49. Denner J, Specke V, Thiesen U, Karlas A, Kurth R (2003) Genetic alterations of the long terminal repeat of an ecotropic porcine endogenous retrovirus PERV during passage in human cells. Virology 314:125-133
50. Scheef G, Fischer N, Krach U, Tönjes R (2001) The number of a U3 repeat box acting as an enhancer in long terminal repeats of polytropic replication-competent porcine endogenous retroviruses dynamically fluctuates during serial virus passages in human cells. J Virol 75:6933-6940
51. Harrison I, Takeuchi Y, Bartosch B, Stoye JP (2004) Determinants of high titer in recombinant porcine endogenous retroviruses. J Virol 78:13871-13879
52. Oldmixon BA, Woods JC, Ericsson TA, Wilson CA, White-Scharf ME, Andersson G, Greenstein JL, Schuurmann HJ, Patience C (2002) Porcine endogenous retrovirus transmission characteristics of an inbred herd of miniature swine. J Virol 76:3045-3048
53. Wood JC, Quinn G, Suling KM, Oldmixon BA, Van Tine BA, Cina R, Arn S, Huanq CA, Scobie L, Onions DE, Sachs DH, Schuurmann HJ, Fishman JA, Patience C (2004) Identification of exogenous forms of human-tropic porcine endogenous retrovirus in miniature swine. J Virol 78:2494-2501
54. Bartosch B, Stefanidis D, Myers R, Weiss R, Patience C, Takeuchi Y (2004) Evidence and consequence of porcine endogenous retrovirus recombination. J Virol 78:13880-13890
55. Martin SI, Wilkinson R, Fishman JA (2006) Genomic presence of recombinant porcine endogenous retrovirus in transmitting miniature swine. Virol J 3:91-96
56. Lavillette D, Kabat D (2004) Porcine endogenous retroviruses infect cells lacking cognate receptors by an alternative pathway: implications for retrovirus evolution and xenotransplantation. J Virol 78(16):8868-8877
57. Barnett AL, Wensel WL, Li W, Fass D, Cunningham JM (2003) Structure and mechanism of a coreceptor for infection by a pathogenic feline retrovirus. J Virol 77:2717-2729
58. Wensel DL, Li W, Cunningham JM JM (2003) A virus-virus interaction circumvents the virus receptor requirement for infection by pathogenic retroviruses. J Virol 77:3460-3469
59. Gemeniano M, Mpanju O, Salomon DR, Eiden MV, Wilson CA (2006) The infectivity and host range of the ecotropic porcine endogenous retrovirus, PERV-C, is modulated by residues in the C-terminal region of its surface envelope protein. Virology 346:108-117
60. Perryman S, Nishio J, Chesebro B (1991) Complete nucleotide sequence of Friend murine leukemia virus, strain FB29. Nucleic Acids Res 19:6950
61. Donahue PR, Hoover EA, Beltz GA, Riedel N, Hirsch VM, Overbaugh J, Mullins JI (1988) Strong sequence conservation among horizontally transmissible minimally pathogenic feline leukemia viruses. J Virol 62:722-731
62. Fiebig U, Hartmann MG, Bannert N, Kurth R, Denner J (2006) Transspecies transmission of the endogenous koala retrovirus. J Virol 80:5651-5654
63. Delassus S, Sonigo P, Wain-Hobson S (1989) Genetic organization of gibbon ape leukemia virus. Virology 173:205-213