Long-term effects of PERV-specific RNA interference in transgenic pigs

Xenotransplantation

Volumn 19, Issue 2, 2012, Pages 112-121

  Semaan, Marwan ^a   Kaulitz, Danny ^a   Petersen, Björn ^b   Niemann, Heiner ^b   Denner, Joachim ^a  

^a ROBERT KOCH INSTITUTE   (Germany)

^b FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

Porcine endogenous retroviruses (PERV); RNA interference; Safety of xenotransplantation; Transgenic pigs

Indexed keywords

SHORT HAIRPIN RNA;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENDOGENOUS RETROVIRUS; GENE SILENCING; NONHUMAN; NUCLEOTIDE SEQUENCE; PORCINE ENDOGENOUS RETROVIRUS; PRIORITY JOURNAL; RNA INTERFERENCE; SAFETY; STRUCTURAL GENE; TRANSGENIC PIG; TREATMENT OUTCOME; VIRUS INHIBITION; VIRUS TRANSMISSION; XENOTRANSPLANTATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASE SEQUENCE; DNA, VIRAL; ENDOGENOUS RETROVIRUSES; GENE EXPRESSION; GENES, POL; GREEN FLUORESCENT PROTEINS; HUMANS; ORGAN SPECIFICITY; REAL-TIME POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SWINE; TIME FACTORS; TRANSPLANTATION, HETEROLOGOUS; VIRAL PROTEINS;

EID: 84859826957     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/j.1399-3089.2012.00683.x     Document Type: Article

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