Simultaneous regeneration of articular cartilage and subchondral bone in vivo using MSCs induced by a spatially controlled gene delivery system in bilayered integrated scaffolds

Biomaterials

Volumn 32, Issue 21, 2011, Pages 4793-4805

  Chen, Jiangning ^a   Chen, Huan ^a   Li, Pei ^a   Diao, Huajia ^a   Zhu, Shiyu ^a   Dong, Lei ^a   Wang, Rui ^b   Guo, Ting ^b   Zhao, Jianning ^b   Zhang, Junfeng ^a  

^a NANJING UNIVERSITY   (China)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Bilayered scaffold; Local gene delivery; Mesenchymal stem cells; Osteochondral tissue

Indexed keywords

ARTICULAR CARTILAGES; BILAYERED SCAFFOLD; BONE REGENERATION; CELL POPULATIONS; CHITOSAN-GELATIN SCAFFOLDS; CHONDROCYTES; CHONDROGENIC; COMPLEX TISSUES; DEFECT MODEL; GENE DELIVERY SYSTEMS; IN-VITRO; IN-VIVO; LOCAL GENE DELIVERY; LOCALIZED GENE DELIVERY; MESENCHYMAL STEM CELL; OPTIMAL MODEL; ORGAN SYSTEMS; OSTEOCHONDRAL; OSTEOCHONDRAL DEFECTS; OSTEOCHONDRAL TISSUE ENGINEERING; OSTEOCHONDRAL TISSUES; OSTEOGENIC; RABBIT KNEES; TISSUE REGENERATION;

BIOMIMETICS; BONE; CARTILAGE; CELL CULTURE; CELL PROLIFERATION; DEFECTS; DNA; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; HISTOLOGY; OSTEOBLASTS; STEM CELLS; TISSUE;

SCAFFOLDS (BIOLOGY);

BONE MORPHOGENETIC PROTEIN 2; CHITOSAN; GELATIN; HYDROXYAPATITE; PLASMID DNA; TISSUE SCAFFOLD; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; ARTICULAR CARTILAGE; BONE REGENERATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE ACTIVATION; GENE DELIVERY SYSTEM; GENE TARGETING; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; TISSUE REGENERATION;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE MORPHOGENETIC PROTEIN 2; BONE REGENERATION; CARTILAGE, ARTICULAR; CELL PROLIFERATION; CELLS, CULTURED; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; MATERIALS TESTING; MESENCHYMAL STEM CELLS; RABBITS; TISSUE SCAFFOLDS; TRANSFORMING GROWTH FACTOR BETA1;

ORYCTOLAGUS CUNICULUS;

EID: 79955758751     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.03.041     Document Type: Article

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