Spatiotemporally limited BDNF and GDNF overexpression rescues motoneurons destined to die and induces elongative axon growth

Experimental Neurology

Volumn 261, Issue , 2014, Pages 367-376

  Pajenda, Gholam ^a,c   Hercher, David ^a,b   Márton, Gábor ^d   Pajer, Krisztián ^d   Feichtinger, Georg ^a,b,e   Maléth, József ^d   Redl, Heinz ^a,b   Nógrádi, Antal ^a,d  

^a FEDERAL RESEARCH AND TRAINING CENTRE FOR FORESTS   (Austria)

^b AUVA Soziale Unfallversicherung   (Austria)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

^d UNIVERSITY OF SZEGED   (Hungary)

^e UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Adipose tissue derived stem cells; Axonal growth; BDNF; GDNF; Reinnervation; Transfection; Ventral root avulsion

Indexed keywords

AMIDINE; BRAIN DERIVED NEUROTROPHIC FACTOR; DIAMIDINO COMPOUND 253/50; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; CHOLINE ACETYLTRANSFERASE; NEUROTROPHIC FACTOR; NEUROTROPHIN;

ADIPOSE TISSUE; ANIMAL; ANIMAL EMBRYO; CYTOLOGY; DIAGNOSTIC USE; DISEASE MODEL; FEMALE; GENE EXPRESSION REGULATION; GENETICS; LOCOMOTION; MALE; METABOLISM; MOTONEURON; MOUSE; NERVE FIBER; PERIPHERAL NERVOUS SYSTEM DISEASES; PHYSIOLOGY; RAT; SPINAL GANGLION; SPRAGUE DAWLEY RAT; STEM CELL; STEM CELL TRANSPLANTATION; ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN BINDING; ARTICLE; BDNF GENE; BIOTINYLATION; CELL POPULATION; CELL REGENERATION; CELL SURVIVAL; CENTRIFUGATION; CONTROLLED STUDY; DNA IMMUNIZATION; EMBRYO; EPIDIDYMIS FAT; EX VIVO GENE TRANSFER; GDNF GENE; GENE OVEREXPRESSION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MORPHOLOGY; MYELINATION; NERVE FIBER GROWTH; NERVE SPROUTING; NEURITE; NONHUMAN; PLASMID; PROTEIN EXPRESSION; REGENERATION; REINNERVATION;

ADIPOSE TISSUE; AMIDINES; ANIMALS; AXONS; BRAIN-DERIVED NEUROTROPHIC FACTOR; DISEASE MODELS, ANIMAL; EMBRYO, MAMMALIAN; FEMALE; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; LOCOMOTION; MALE; MICE; MOTOR NEURONS; PERIPHERAL NERVOUS SYSTEM DISEASES; RATS; RATS, SPRAGUE-DAWLEY; STEM CELL TRANSPLANTATION; STEM CELLS;

EID: 84905454766     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2014.05.019     Document Type: Article

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