Local injection of BDNF producing mesenchymal stem cells increases neuronal survival and synaptic stability following ventral root avulsion

Neurobiology of Disease

Volumn 33, Issue 2, 2009, Pages 290-300

  Rodrigues Hell, Rafaela Chitarra ^a,b   Silva Costa, Miriam Maria ^a   Goes, Alfredo Miranda ^a   Oliveira, Alexandre L R ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Glial reaction; Motoneuron; Spinal cord; Stem cells; Ventral root avulsion

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA; NEUROTROPHIN; SYNAPTOPHYSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AVULSION INJURY; BRAIN SURGERY; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; DRUG INHIBITION; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MESENCHYMAL STEM CELL TRANSPLANTATION; NERVE CELL CULTURE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SPINAL CORD; SYNAPSE; UPREGULATION; VENTRAL ROOT;

ANIMALS; ASTROCYTES; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; MOTOR NEURONS; NEUROPROTECTIVE AGENTS; RADICULOPATHY; RATS; RNA, MESSENGER; SPINAL NERVE ROOTS; SYNAPSES; SYNAPTOPHYSIN;

EID: 58149492529     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2008.10.017     Document Type: Article

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