메뉴 건너뛰기




Volumn 26, Issue 1, 2009, Pages 67-80

Neural progenitor cells enhance the survival and axonal regeneration of injured motoneurons after transplantation into the avulsed ventral horn of adult rats

Author keywords

Neural progenitor cells; Regeneration; Spinal motoneurons; Spinal root avulsion; Survival

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; FLUOROGOLD; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR;

EID: 59849127305     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2008.0656     Document Type: Article
Times cited : (31)

References (74)
  • 1
    • 0141744970 scopus 로고    scopus 로고
    • Reliability of three classification systems measuring active motion in brachial plexus birth palsy
    • Bae, D.S., Waters, P.M., and Zurakowaki, D. (2003). Reliability of three classification systems measuring active motion in brachial plexus birth palsy. J. Bone Joint Surg. Am. 85-A, 1733-1738.
    • (2003) J. Bone Joint Surg. Am , vol.85-A , pp. 1733-1738
    • Bae, D.S.1    Waters, P.M.2    Zurakowaki, D.3
  • 2
    • 0034032642 scopus 로고    scopus 로고
    • Cell replacement therapies for central nervous system disorders
    • Bjorklund, A., and Lindvall, O. (2000). Cell replacement therapies for central nervous system disorders. Nat Neurosci. 3, 537-544.
    • (2000) Nat Neurosci , vol.3 , pp. 537-544
    • Bjorklund, A.1    Lindvall, O.2
  • 3
    • 4544293725 scopus 로고    scopus 로고
    • Rescue and sprouting of motoneurons following ventral root avulsion and reimplantation combined with intraspinal adeno-associated viral vector-mediated expression of glial cell line-derived neurotrophic factor or brain-derived neurotrophic factor
    • Blits, B., Carlstedt, T.P., Ruitenberg, M.J., de Winter, F., Hermens, W.T., Dijkhuizen, P.A., Claasens, J.W., Eggers, R., van der Sluis, R., Tenenbaum, L., Boer, G.J., and Verhaagen, J. (2004). Rescue and sprouting of motoneurons following ventral root avulsion and reimplantation combined with intraspinal adeno-associated viral vector-mediated expression of glial cell line-derived neurotrophic factor or brain-derived neurotrophic factor. Exp. Neurol. 189, 303-316.
    • (2004) Exp. Neurol , vol.189 , pp. 303-316
    • Blits, B.1    Carlstedt, T.P.2    Ruitenberg, M.J.3    de Winter, F.4    Hermens, W.T.5    Dijkhuizen, P.A.6    Claasens, J.W.7    Eggers, R.8    van der Sluis, R.9    Tenenbaum, L.10    Boer, G.J.11    Verhaagen, J.12
  • 5
    • 0036433386 scopus 로고    scopus 로고
    • Differentiation of engrafted neuronal-restricted precursor cells is inhibited in the traumatically injured spinal cord
    • Cao, Q.L., Howard, R.M., Dennison, J.B., and Whittemore, S.R. (2002). Differentiation of engrafted neuronal-restricted precursor cells is inhibited in the traumatically injured spinal cord. Exp. Neurol. 177, 349-359.
    • (2002) Exp. Neurol , vol.177 , pp. 349-359
    • Cao, Q.L.1    Howard, R.M.2    Dennison, J.B.3    Whittemore, S.R.4
  • 6
    • 0035148507 scopus 로고    scopus 로고
    • Pluripotent stem cells engrafted into the normal or lesioned adult rat spinal cord are restricted to a glial lineage
    • Cao, Q.L., Zhang, Y.P., Howard, R.M., Walters, W.M., Tsoulfas, P., and Whittemore, S.R. (2001). Pluripotent stem cells engrafted into the normal or lesioned adult rat spinal cord are restricted to a glial lineage. Exp. Neurol. 167, 48-51.
    • (2001) Exp. Neurol , vol.167 , pp. 48-51
    • Cao, Q.L.1    Zhang, Y.P.2    Howard, R.M.3    Walters, W.M.4    Tsoulfas, P.5    Whittemore, S.R.6
  • 7
    • 0031026709 scopus 로고    scopus 로고
    • Nerve fibre regeneration across the peripheral-central transitional zone
    • Carlstedt, T., Cullheim, S., Risling, M., and Ulfhake, B. (1997a). Nerve fibre regeneration across the peripheral-central transitional zone. J. Anat. 190, 51-56.
    • (1997) J. Anat , vol.190 , pp. 51-56
    • Carlstedt, T.1    Cullheim, S.2    Risling, M.3    Ulfhake, B.4
  • 8
    • 0027471548 scopus 로고
    • Functional recovery after ventral root avulsion and implantation in the spinal cord
    • Carlstedt, T. (1993). Functional recovery after ventral root avulsion and implantation in the spinal cord. Clin. Neurol. Neurosurg. 95, S109-S111.
    • (1993) Clin. Neurol. Neurosurg , vol.95
    • Carlstedt, T.1
  • 9
    • 0028872012 scopus 로고    scopus 로고
    • Return of function after spinal cord implantation of avulsed spinal nerve roots
    • Carlstedt, T., Grane, P., Hallin, R.G., and Nore'n, G. (1997b). Return of function after spinal cord implantation of avulsed spinal nerve roots. Lancet 346, 1323-1325.
    • (1997) Lancet , vol.346 , pp. 1323-1325
    • Carlstedt, T.1    Grane, P.2    Hallin, R.G.3    Nore'n, G.4
  • 10
    • 0032873649 scopus 로고    scopus 로고
    • Long term effects of a single dose of brain-derived neurotrophic factor (BDNF ) on motoneuron survival following spinal root avulsion in the adult rat
    • Chai, H., Wu, W., So, K.F., Prevette, D.M., and Oppenheim, R.W. (1999). Long term effects of a single dose of brain-derived neurotrophic factor (BDNF ) on motoneuron survival following spinal root avulsion in the adult rat. Neurosci. Lett. 274, 147-150.
    • (1999) Neurosci. Lett , vol.274 , pp. 147-150
    • Chai, H.1    Wu, W.2    So, K.F.3    Prevette, D.M.4    Oppenheim, R.W.5
  • 11
    • 0035809758 scopus 로고    scopus 로고
    • Caspase inhibitors promote the survival of avulsed spinal motoneurons in neonatal rats
    • Chan, Y.M., Wu, W., Yip, H., So, K-F, and Oppenheim, R. (2001). Caspase inhibitors promote the survival of avulsed spinal motoneurons in neonatal rats. NeuroReport 12, 541-545.
    • (2001) NeuroReport , vol.12 , pp. 541-545
    • Chan, Y.M.1    Wu, W.2    Yip, H.3    So, K.-F.4    Oppenheim, R.5
  • 12
    • 0034714306 scopus 로고    scopus 로고
    • Characterization and intraspinal grafting of EGF/bFGF-dependent neurospheres derived from embryonic rat spinal cord
    • Chow, S.Y., Moul, J., Tobias, C.A., Himes, B.T., Liu, Y., Obrocka, M., Hodge, L., Tessler, A., and Fischer, I. (2000). Characterization and intraspinal grafting of EGF/bFGF-dependent neurospheres derived from embryonic rat spinal cord. Brain Res. 874, 87-106.
    • (2000) Brain Res , vol.874 , pp. 87-106
    • Chow, S.Y.1    Moul, J.2    Tobias, C.A.3    Himes, B.T.4    Liu, Y.5    Obrocka, M.6    Hodge, L.7    Tessler, A.8    Fischer, I.9
  • 14
    • 0024374643 scopus 로고
    • Motoneurons reinnervate skeletal muscle after ventral root implantation into spinal cord of the cat
    • Cullheim, S., Carlstedt, T., Linda, H., Risling, M., and Ulfhake, B. (1989). Motoneurons reinnervate skeletal muscle after ventral root implantation into spinal cord of the cat. Neuroscience 29, 725-733.
    • (1989) Neuroscience , vol.29 , pp. 725-733
    • Cullheim, S.1    Carlstedt, T.2    Linda, H.3    Risling, M.4    Ulfhake, B.5
  • 16
    • 15944388208 scopus 로고    scopus 로고
    • Optimising plasticity: Environmental and training associated factors in transplant-mediated brain repair
    • Dobrossy, M.D., and Dunnett, S.B. (2005). Optimising plasticity: environmental and training associated factors in transplant-mediated brain repair. Rev. Neurosci. 16, 1-21.
    • (2005) Rev. Neurosci , vol.16 , pp. 1-21
    • Dobrossy, M.D.1    Dunnett, S.B.2
  • 17
    • 0038024459 scopus 로고    scopus 로고
    • Obstetrical brachial plexus palsy
    • Dunham, E.A. (2003). Obstetrical brachial plexus palsy. Orthop. Nurs. 22, 106-116.
    • (2003) Orthop. Nurs , vol.22 , pp. 106-116
    • Dunham, E.A.1
  • 18
    • 0036154612 scopus 로고    scopus 로고
    • Outcomes of surgical treatment of brachial plexus injuries using nerve grafting and nerve transfers
    • El-Gammal, T.A., and Fathi, N.A. (2002). Outcomes of surgical treatment of brachial plexus injuries using nerve grafting and nerve transfers. J. Reconstr. Microsurg. 18, 7-15.
    • (2002) J. Reconstr. Microsurg , vol.18 , pp. 7-15
    • El-Gammal, T.A.1    Fathi, N.A.2
  • 19
    • 33646576505 scopus 로고    scopus 로고
    • Functional considerations of stem cell transplantation therapy for spinal cord repair
    • Enzmann, G.U., Benton, R.L., Talbott, J.F., Cao, Q.L., and Whittemore, S.R. (2006). Functional considerations of stem cell transplantation therapy for spinal cord repair. J. Neurotrauma 23, 479-495.
    • (2006) J. Neurotrauma , vol.23 , pp. 479-495
    • Enzmann, G.U.1    Benton, R.L.2    Talbott, J.F.3    Cao, Q.L.4    Whittemore, S.R.5
  • 20
    • 0034589603 scopus 로고    scopus 로고
    • Candidate cells for transplantation into the injured CNS
    • Fischer, I. (2000). Candidate cells for transplantation into the injured CNS. Prog. Brain Res. 128, 253-257.
    • (2000) Prog. Brain Res , vol.128 , pp. 253-257
    • Fischer, I.1
  • 21
    • 0034712047 scopus 로고    scopus 로고
    • Mammalian neural stem cells
    • Gage, F.H. (2000). Mammalian neural stem cells. Science 287, 1433-1438.
    • (2000) Science , vol.287 , pp. 1433-1438
    • Gage, F.H.1
  • 22
    • 13544273269 scopus 로고    scopus 로고
    • Human neural stem cell derived cholinergic neurons innervate muscle in motoneuron deficient adult rats
    • Gao, J, Coggeshall, R.E., Tarasenko, Y.I., and Wu, P. (2005). Human neural stem cell derived cholinergic neurons innervate muscle in motoneuron deficient adult rats. Neuroscience 131, 257-262.
    • (2005) Neuroscience , vol.131 , pp. 257-262
    • Gao, J.1    Coggeshall, R.E.2    Tarasenko, Y.I.3    Wu, P.4
  • 23
    • 16944366150 scopus 로고    scopus 로고
    • Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury
    • Grill, R., Murai, K., Blesch, A., Gage, F.H., and Tuszynski, M.H. (1997). Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. J. Neurosci. 17, 5560-5572.
    • (1997) J. Neurosci , vol.17 , pp. 5560-5572
    • Grill, R.1    Murai, K.2    Blesch, A.3    Gage, F.H.4    Tuszynski, M.H.5
  • 24
    • 2342614777 scopus 로고    scopus 로고
    • Survival, regeneration and functional recovery of motoneurons in adult rats by reimplantation of ventral root following spinal root avulsion
    • Gu, H.Y., Chai, H., Zhang, J.Y., Yao, Z.B., Zhou, L.H., Wong, W.M., Bruce, I., and Wu, W. (2004). Survival, regeneration and functional recovery of motoneurons in adult rats by reimplantation of ventral root following spinal root avulsion. Eur. J. Neurosci. 19, 2123-2131.
    • (2004) Eur. J. Neurosci , vol.19 , pp. 2123-2131
    • Gu, H.Y.1    Chai, H.2    Zhang, J.Y.3    Yao, Z.B.4    Zhou, L.H.5    Wong, W.M.6    Bruce, I.7    Wu, W.8
  • 25
    • 0033003105 scopus 로고    scopus 로고
    • Spinal cord implantation of avulsed ventral roots in primates; correlation between restored motor function and morphology
    • Hallin, R.G., Carlstedt, T., Nilsson-Remahl, I., and Risling, M. (1999). Spinal cord implantation of avulsed ventral roots in primates; correlation between restored motor function and morphology. Exp. Brain. Res. 124, 304-310.
    • (1999) Exp. Brain. Res , vol.124 , pp. 304-310
    • Hallin, R.G.1    Carlstedt, T.2    Nilsson-Remahl, I.3    Risling, M.4
  • 26
    • 0036436237 scopus 로고    scopus 로고
    • Grafted lineage-restricted precursors differentiate exclusively into neurons in the adult spinal cord
    • Han, S.S., Kang, D.Y., Mujtaba, T., Rao, M.S., and Fischer, I. (2002). Grafted lineage-restricted precursors differentiate exclusively into neurons in the adult spinal cord. Exp. Neurol. 177, 360-375.
    • (2002) Exp. Neurol , vol.177 , pp. 360-375
    • Han, S.S.1    Kang, D.Y.2    Mujtaba, T.3    Rao, M.S.4    Fischer, I.5
  • 29
    • 0030026068 scopus 로고    scopus 로고
    • Reinnervation and reimplanted ventral rootlets in the cervical spinal cord of the cat
    • Hoffmann, C.F., Marani, E., Gert, V.D., Kamp, W., and Thomeer, R.T. (1996). Reinnervation and reimplanted ventral rootlets in the cervical spinal cord of the cat. J. Neurosurg. 84, 234-243.
    • (1996) J. Neurosurg , vol.84 , pp. 234-243
    • Hoffmann, C.F.1    Marani, E.2    Gert, V.D.3    Kamp, W.4    Thomeer, R.T.5
  • 30
    • 38049007617 scopus 로고    scopus 로고
    • Astrocytes enhance long-term survival of cholinergic neurons differentiated from human fetal neural stem cells
    • Jordan, P.M., Cain, L.D., and Wu, P. (2008). Astrocytes enhance long-term survival of cholinergic neurons differentiated from human fetal neural stem cells. J. Neurosci. Res. 86, 35-47.
    • (2008) J. Neurosci. Res , vol.86 , pp. 35-47
    • Jordan, P.M.1    Cain, L.D.2    Wu, P.3
  • 31
    • 33645455547 scopus 로고    scopus 로고
    • Delayed transplantation of adult neural precursor cells promotes remyelination and functional neurological recovery after spinal cord injury
    • Karimi-Abdolrezaee, S., Eftekharpour, E., Wang, J., Morshead, C., and Fehlings, M. (2006). Delayed transplantation of adult neural precursor cells promotes remyelination and functional neurological recovery after spinal cord injury. J. Neurosci. 26, 3377-3389.
    • (2006) J. Neurosci , vol.26 , pp. 3377-3389
    • Karimi-Abdolrezaee, S.1    Eftekharpour, E.2    Wang, J.3    Morshead, C.4    Fehlings, M.5
  • 33
    • 0031128211 scopus 로고    scopus 로고
    • BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth
    • Kishino, A., Ishige, Y., Tatuno, T., Nakayama, C., and Noguchi, H. (1997). BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth. Exp. Neurol. 144, 273-286.
    • (1997) Exp. Neurol , vol.144 , pp. 273-286
    • Kishino, A.1    Ishige, Y.2    Tatuno, T.3    Nakayama, C.4    Noguchi, H.5
  • 34
    • 0027481752 scopus 로고
    • Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo
    • Koliatsos, V.E., Clatterbuck, R.E., Winslow, J.W., Cayouette, M.H., and Price, D.L. (1993). Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo. Neuron 10, 359-367.
    • (1993) Neuron , vol.10 , pp. 359-367
    • Koliatsos, V.E.1    Clatterbuck, R.E.2    Winslow, J.W.3    Cayouette, M.H.4    Price, D.L.5
  • 35
    • 38949206409 scopus 로고    scopus 로고
    • Human stem cell grafts as therapies for motor neuron disease
    • Koliatsos, V.E., Xu, L.Y., and Yan, J. (2008). Human stem cell grafts as therapies for motor neuron disease. Expert Opin. Biol. Ther. 8, 137-141.
    • (2008) Expert Opin. Biol. Ther , vol.8 , pp. 137-141
    • Koliatsos, V.E.1    Xu, L.Y.2    Yan, J.3
  • 36
    • 15544382576 scopus 로고    scopus 로고
    • Endogenous and exogenous CNS derived stem/progenitor cell approaches for neurotrauma
    • Kulbatski, I., Mothe, A.J., Nomura, H., and Tator, C.H. (2005). Endogenous and exogenous CNS derived stem/progenitor cell approaches for neurotrauma. Curr. Drug Targets 6, 111-126.
    • (2005) Curr. Drug Targets , vol.6 , pp. 111-126
    • Kulbatski, I.1    Mothe, A.J.2    Nomura, H.3    Tator, C.H.4
  • 37
    • 0028822549 scopus 로고
    • Rescue of adult mouse motoneurons from injury-induced cell death by a glial cell line-derived neurotrophic factor
    • Li, L., Wu, W., Lin, L.F., Lei, M., Oppenheim, R.W., and Houenou, L.J. (1995). Rescue of adult mouse motoneurons from injury-induced cell death by a glial cell line-derived neurotrophic factor. Proc. Natl. Acad. Sci. USA 92, 9771-9775.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9771-9775
    • Li, L.1    Wu, W.2    Lin, L.F.3    Lei, M.4    Oppenheim, R.W.5    Houenou, L.J.6
  • 38
    • 7244232763 scopus 로고    scopus 로고
    • Neural stem cells protect against glutamate-induced excitotoxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors
    • Llado, J., Haenggeli, C., Maragakis, N.J., Snyder, E.Y., and Rothstein, J.D. (2004). Neural stem cells protect against glutamate-induced excitotoxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors. Mol. Cell. Neurosci. 27, 322-331.
    • (2004) Mol. Cell. Neurosci , vol.27 , pp. 322-331
    • Llado, J.1    Haenggeli, C.2    Maragakis, N.J.3    Snyder, E.Y.4    Rothstein, J.D.5
  • 39
    • 0038054469 scopus 로고    scopus 로고
    • Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury
    • Lu, P., Jones, L.L., Snyder, E.Y., and Tuszynski, M.H. (2003). Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Exp. Neruol. 181, 115-129.
    • (2003) Exp. Neruol , vol.181 , pp. 115-129
    • Lu, P.1    Jones, L.L.2    Snyder, E.Y.3    Tuszynski, M.H.4
  • 40
    • 0023284246 scopus 로고
    • Injuries of the brachial plexus and neighboring peripheral nerves in vertebral fractures and other trauma of the cervical spine
    • Narakas, A.O. (1987). Injuries of the brachial plexus and neighboring peripheral nerves in vertebral fractures and other trauma of the cervical spine. Orthopade 16, 81-86.
    • (1987) Orthopade , vol.16 , pp. 81-86
    • Narakas, A.O.1
  • 41
    • 0036158965 scopus 로고    scopus 로고
    • Bcl-2 and GDNF delivered by HSV-mediated gene transfer after spinal root avulsion provide a synergistic effect
    • Natsume, A., Mata, M., Wolfe, D., Oligino, T., Goss, J., Huang, S., Glorioso, J., and Fink, D.J. (2002). Bcl-2 and GDNF delivered by HSV-mediated gene transfer after spinal root avulsion provide a synergistic effect. J. Neurotrauma. 19, 61-68.
    • (2002) J. Neurotrauma , vol.19 , pp. 61-68
    • Natsume, A.1    Mata, M.2    Wolfe, D.3    Oligino, T.4    Goss, J.5    Huang, S.6    Glorioso, J.7    Fink, D.J.8
  • 42
    • 0028853885 scopus 로고
    • Brain-derived neurotrophic factor promotes survival and blocks nitric oxide synthase expression in adult rat spinal motoneurons after ventral root avulsion
    • Novikov, L., Novikova, L., and Kellerth, J.O. (1995). Brain-derived neurotrophic factor promotes survival and blocks nitric oxide synthase expression in adult rat spinal motoneurons after ventral root avulsion. Neurosci. Lett. 200, 45-48.
    • (1995) Neurosci. Lett , vol.200 , pp. 45-48
    • Novikov, L.1    Novikova, L.2    Kellerth, J.O.3
  • 43
    • 0037106211 scopus 로고    scopus 로고
    • Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats
    • Ogawa, Y., Sawamoto, K., Miyata, T., Miyao, S., Watanabe, M., Nakamura, M., Bregman, B.S., Koike, M., Uchiyama, Y., Toyama, Y., and Okano, H. (2002). Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats. J. Neurosci. Res. 69, 925-933.
    • (2002) J. Neurosci. Res , vol.69 , pp. 925-933
    • Ogawa, Y.1    Sawamoto, K.2    Miyata, T.3    Miyao, S.4    Watanabe, M.5    Nakamura, M.6    Bregman, B.S.7    Koike, M.8    Uchiyama, Y.9    Toyama, Y.10    Okano, H.11
  • 44
    • 0029776880 scopus 로고    scopus 로고
    • Reconstruction of the glial environment of a photochemically induced lesion in the rat spinal cord by transplantation of mixed glial cells
    • Olby, N.J., and Blakemore, W.F. (1996). Reconstruction of the glial environment of a photochemically induced lesion in the rat spinal cord by transplantation of mixed glial cells. J. Neurocytol. 25, 481-498.
    • (1996) J. Neurocytol , vol.25 , pp. 481-498
    • Olby, N.J.1    Blakemore, W.F.2
  • 45
    • 0030960434 scopus 로고    scopus 로고
    • Altered differentiation of CNS neural progenitor cells after transplantation into the injured adult rat spinal cord
    • Onifer, S.M., Cannon, A.B., and Whittemore, S.R. (1997). Altered differentiation of CNS neural progenitor cells after transplantation into the injured adult rat spinal cord. Cell Transplant. 6, 327-338.
    • (1997) Cell Transplant , vol.6 , pp. 327-338
    • Onifer, S.M.1    Cannon, A.B.2    Whittemore, S.R.3
  • 47
    • 0036844019 scopus 로고    scopus 로고
    • Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons
    • Ourednik, J., Ourednik, V., Lynch, W.P., Schachner, M., and Snyder, E.Y. (2002). Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons. Nat. Biotechnol. 20, 1103-1110.
    • (2002) Nat. Biotechnol , vol.20 , pp. 1103-1110
    • Ourednik, J.1    Ourednik, V.2    Lynch, W.P.3    Schachner, M.4    Snyder, E.Y.5
  • 48
    • 0032695766 scopus 로고    scopus 로고
    • Neural stemcells - a versatile tool for cell replacement and gene therapy in the central nervous system
    • Ourednik, V., Ourednik, J., Park, K.I., and Synder, E.Y. (1999). Neural stemcells - a versatile tool for cell replacement and gene therapy in the central nervous system. Clin. Genet. 56, 267-278.
    • (1999) Clin. Genet , vol.56 , pp. 267-278
    • Ourednik, V.1    Ourednik, J.2    Park, K.I.3    Synder, E.Y.4
  • 51
    • 0026535505 scopus 로고
    • Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
    • Reynolds, B.A., and Weiss, S. (1992). Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255, 1707-1710.
    • (1992) Science , vol.255 , pp. 1707-1710
    • Reynolds, B.A.1    Weiss, S.2
  • 52
    • 0027070473 scopus 로고
    • Brain derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section
    • Sendtner, M., Holtmann, B., Kolbeck, R., Thoenen, H., and Barde, Y.A. (1992). Brain derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature 360, 757-759.
    • (1992) Nature , vol.360 , pp. 757-759
    • Sendtner, M.1    Holtmann, B.2    Kolbeck, R.3    Thoenen, H.4    Barde, Y.A.5
  • 53
    • 0024235453 scopus 로고
    • Transplantation of immature and mature astrocytes and their effect on scar formation in the lesioned central nervous system
    • Smith, G.M., and Silver, J. (1988). Transplantation of immature and mature astrocytes and their effect on scar formation in the lesioned central nervous system. Prog. Brain Res. 78, 353-361.
    • (1988) Prog. Brain Res , vol.78 , pp. 353-361
    • Smith, G.M.1    Silver, J.2
  • 54
    • 0345195968 scopus 로고    scopus 로고
    • Experimental strategies to promote axonal regeneration after traumatic central nervous system injury
    • Stichel, C.C., and Muller, H.W. (1998). Experimental strategies to promote axonal regeneration after traumatic central nervous system injury. Prog. Neurobiol. 56, 119-148.
    • (1998) Prog. Neurobiol , vol.56 , pp. 119-148
    • Stichel, C.C.1    Muller, H.W.2
  • 55
    • 34447649395 scopus 로고    scopus 로고
    • Lithium enhances proliferation and neuronal differentiation of neural progenitor cells in vitro and after transplantation into the adult rat spinal cord
    • Su, H., Chu, T., and Wu, W. (2007). Lithium enhances proliferation and neuronal differentiation of neural progenitor cells in vitro and after transplantation into the adult rat spinal cord. Exp. Neurol. 206, 296-307.
    • (2007) Exp. Neurol , vol.206 , pp. 296-307
    • Su, H.1    Chu, T.2    Wu, W.3
  • 56
    • 0029967893 scopus 로고    scopus 로고
    • Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo
    • Suhonen, J.O., Peterson, D.A., Ray, J., and Gage, F.H. (1996). Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo. Nature 383, 624-627.
    • (1996) Nature , vol.383 , pp. 624-627
    • Suhonen, J.O.1    Peterson, D.A.2    Ray, J.3    Gage, F.H.4
  • 57
    • 0030881885 scopus 로고    scopus 로고
    • Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex
    • Synder, E.Y., Yoon, C., Flax, J.D., and Macklis, J.D. (1997). Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex. Proc. Natl. Acad. Sci. USA 94, 11663-11668.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 11663-11668
    • Synder, E.Y.1    Yoon, C.2    Flax, J.D.3    Macklis, J.D.4
  • 58
    • 0032879746 scopus 로고    scopus 로고
    • Outcomes of brachial plexus reconstruction in 204 patients with devastating paralysis
    • Terzis, J.K., Vekris, M.D., and Soucacos, P.N. (1999). Outcomes of brachial plexus reconstruction in 204 patients with devastating paralysis. Plast. Reconstr. Surg. 104, 1221-1240.
    • (1999) Plast. Reconstr. Surg , vol.104 , pp. 1221-1240
    • Terzis, J.K.1    Vekris, M.D.2    Soucacos, P.N.3
  • 59
    • 0030054303 scopus 로고    scopus 로고
    • Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury
    • Tuszynski, M.H., Gabriel, K., Gage, F.H., Suhr, S., Meyer, S., and Rosetti, A. (1996). Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury. Exp. Neurol. 137, 157-173.
    • (1996) Exp. Neurol , vol.137 , pp. 157-173
    • Tuszynski, M.H.1    Gabriel, K.2    Gage, F.H.3    Suhr, S.4    Meyer, S.5    Rosetti, A.6
  • 60
    • 0041317188 scopus 로고    scopus 로고
    • Adult neural progenitor cell grafts survive after acute spinal cord injury and integrate along axonal pathways
    • Vroemen, M., Aigner, L., Winkler, J., and Weidner, N. (2003). Adult neural progenitor cell grafts survive after acute spinal cord injury and integrate along axonal pathways. Eur. J. Neurosci. 18, 743-751.
    • (2003) Eur. J. Neurosci , vol.18 , pp. 743-751
    • Vroemen, M.1    Aigner, L.2    Winkler, J.3    Weidner, N.4
  • 61
    • 0034657174 scopus 로고    scopus 로고
    • Rescue of lesioned adult rat spinal motoneurons by adenoviral gene transfer of glial cell line-derived neurotrophic factor
    • Watabe, K., Ohashi, T., Sakamoto, T., Kawazoe, Y., Takeshima, T., Oyanagi, K., Inoue, K., Eto, Y., and Kim, S.U. (2000). Rescue of lesioned adult rat spinal motoneurons by adenoviral gene transfer of glial cell line-derived neurotrophic factor. J. Neurosci. Res. 60, 511-519.
    • (2000) J. Neurosci. Res , vol.60 , pp. 511-519
    • Watabe, K.1    Ohashi, T.2    Sakamoto, T.3    Kawazoe, Y.4    Takeshima, T.5    Oyanagi, K.6    Inoue, K.7    Eto, Y.8    Kim, S.U.9
  • 62
    • 0027316366 scopus 로고
    • The neurotrophins BDNF, NT-3 and NT-4/5, but not NGF, upregulate the cholinergic phenotype of developing motor neurons
    • Wong, V., Arriaga, R., Ip, N.Y., and Lindsay, R.M. (1993). The neurotrophins BDNF, NT-3 and NT-4/5, but not NGF, upregulate the cholinergic phenotype of developing motor neurons, Eur. J. Neurosci. 5, 466-474.
    • (1993) Eur. J. Neurosci , vol.5 , pp. 466-474
    • Wong, V.1    Arriaga, R.2    Ip, N.Y.3    Lindsay, R.M.4
  • 63
    • 0027154946 scopus 로고
    • Expression of nitric-oxide synthase (NOS) in injured CNS neurons as shown by NADPH diaphorase histochemistry
    • Wu, W. (1993). Expression of nitric-oxide synthase (NOS) in injured CNS neurons as shown by NADPH diaphorase histochemistry. Exp. Neurol. 120, 153-159.
    • (1993) Exp. Neurol , vol.120 , pp. 153-159
    • Wu, W.1
  • 64
    • 0027987963 scopus 로고
    • Implantation of PNS graft inhibits the induction of nitric oxide synthase and enhances the survival of spinal motoneurons due to root avulsion
    • Wu, W., Han, K., Li, L., and Schinco, F.P. (1994a). Implantation of PNS graft inhibits the induction of nitric oxide synthase and enhances the survival of spinal motoneurons due to root avulsion. Exp. Neurol. 129, 335-339.
    • (1994) Exp. Neurol , vol.129 , pp. 335-339
    • Wu, W.1    Han, K.2    Li, L.3    Schinco, F.P.4
  • 65
    • 0038045085 scopus 로고    scopus 로고
    • GDNF and BDNF alter the expression of NOS, c-Jun, and p75 and prevent motoneuron death following spinal root avulsion
    • Wu, W., Li, L., Yick, L.W., Chai, H., Xie, Y.Y., Yang, Y., Prevette, D.M., and Oppenheim, R.W. (2003). GDNF and BDNF alter the expression of NOS, c-Jun, and p75 and prevent motoneuron death following spinal root avulsion. J. Neurotrauma 20, 603-612.
    • (2003) J. Neurotrauma , vol.20 , pp. 603-612
    • Wu, W.1    Li, L.2    Yick, L.W.3    Chai, H.4    Xie, Y.Y.5    Yang, Y.6    Prevette, D.M.7    Oppenheim, R.W.8
  • 66
    • 0028048108 scopus 로고
    • Neuronal nitric oxide synthase is induced in spinal neurons by traumatic injury
    • Wu, W., Liuzzi, F.J., Schinco, F.P., Depto, A., Dawson, T., and Snyder, S.H. (1994b). Neuronal nitric oxide synthase is induced in spinal neurons by traumatic injury. Neuroscience 61, 719-726.
    • (1994) Neuroscience , vol.61 , pp. 719-726
    • Wu, W.1    Liuzzi, F.J.2    Schinco, F.P.3    Depto, A.4    Dawson, T.5    Snyder, S.H.6
  • 67
    • 0030271362 scopus 로고    scopus 로고
    • Potential roles of gene expression change in adult rat spinal motoneurons following axonal injury: A comparison among c-jun, off-affinity nerve growth factor receptor (LNGFR), and nitric oxide synthase (NOS)
    • Wu, W. (1996). Potential roles of gene expression change in adult rat spinal motoneurons following axonal injury: a comparison among c-jun, off-affinity nerve growth factor receptor (LNGFR), and nitric oxide synthase (NOS). Exp. Neurol. 141, 190-200.
    • (1996) Exp. Neurol , vol.141 , pp. 190-200
    • Wu, W.1
  • 69
    • 33644904656 scopus 로고    scopus 로고
    • Microarray analysis of gene expression pattern in adult spinal motoneurons after different types of axonal injuries
    • Yang, Y., Xie, Y.Y., Chai, H., Fan, M., Liu, S., Liu, H., Bruce, I., and Wu, W. (2006). Microarray analysis of gene expression pattern in adult spinal motoneurons after different types of axonal injuries. Brain Res. 1075, 1-12.
    • (2006) Brain Res , vol.1075 , pp. 1-12
    • Yang, Y.1    Xie, Y.Y.2    Chai, H.3    Fan, M.4    Liu, S.5    Liu, H.6    Bruce, I.7    Wu, W.8
  • 70
    • 7544234209 scopus 로고    scopus 로고
    • Differentiation and tropic/trophic effects of exogenous neural precursors in the adult spinal cord
    • Yan, J., Welsh, A.M., Bora, S.H., Snyder, E.Y., and Koliatsos, V.E. (2004). Differentiation and tropic/trophic effects of exogenous neural precursors in the adult spinal cord. J. Comp. Neurol. 480, 101-114.
    • (2004) J. Comp. Neurol , vol.480 , pp. 101-114
    • Yan, J.1    Welsh, A.M.2    Bora, S.H.3    Snyder, E.Y.4    Koliatsos, V.E.5
  • 71
    • 0028854836 scopus 로고
    • In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons
    • Yan, Q., Matheson, C., and Lopez, O.T. (1995). In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons. Nature 373, 341-344.
    • (1995) Nature , vol.373 , pp. 341-344
    • Yan, Q.1    Matheson, C.2    Lopez, O.T.3
  • 72
    • 0034647622 scopus 로고    scopus 로고
    • Effects of neurotrophic factors on motoneuron survival following axonal injury in newborn rats
    • Yuan, Q., Wu, W., So, K.F., Cheung, A.L., Prevette, D.M., and Oppenheim, R.W. (2000). Effects of neurotrophic factors on motoneuron survival following axonal injury in newborn rats. Neuroreport 11, 2237-2241.
    • (2000) Neuroreport , vol.11 , pp. 2237-2241
    • Yuan, Q.1    Wu, W.2    So, K.F.3    Cheung, A.L.4    Prevette, D.M.5    Oppenheim, R.W.6
  • 73
    • 7244236359 scopus 로고    scopus 로고
    • NGF, BDNF, NT-3, and GDNF mRNA expression in rat skeletal muscle following denervation and sensory protection
    • Zhao, C., Veltri, K., Li, S., Bain, J.R., and Fahnestock, M. (2004). NGF, BDNF, NT-3, and GDNF mRNA expression in rat skeletal muscle following denervation and sensory protection. J. Neurotrauma 21, 1468-1478.
    • (2004) J. Neurotrauma , vol.21 , pp. 1468-1478
    • Zhao, C.1    Veltri, K.2    Li, S.3    Bain, J.R.4    Fahnestock, M.5
  • 74
    • 29144497234 scopus 로고    scopus 로고
    • Antisense oligos to neuronal nitric oxide synthase aggravate motoneuron death induced by spinal root avulsion in adult rat
    • Zhou, L.H., and Wu, W. (2006). Antisense oligos to neuronal nitric oxide synthase aggravate motoneuron death induced by spinal root avulsion in adult rat. Exp. Neurol. 197, 84-92.
    • (2006) Exp. Neurol , vol.197 , pp. 84-92
    • Zhou, L.H.1    Wu, W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.