-
2
-
-
0033105864
-
+ channel by Nedd4 in Liddle's syndrome
-
+ channel by Nedd4 in Liddle's syndrome. J Clin Invest 103: 667-673, 1999.
-
(1999)
J Clin Invest
, vol.103
, pp. 667-673
-
-
Abriel, H.1
Loffing, J.2
Rebhun, J.F.3
Pratt, H.4
Schild, L.5
Horisberger, J.D.6
Rotin, D.7
Staub, O.8
-
3
-
-
80052320481
-
- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway
-
- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway. J Am Soc Nephrol 22: 1707-1719, 2011.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 1707-1719
-
-
Arroyo, J.P.1
Lagnaz, D.2
Ronzaud, C.3
Vazquez, N.4
Ko, B.S.5
Moddes, L.6
Ruffieux-Daidie, D.7
Hausel, P.8
Koesters, R.9
Yang, B.10
Stokes, J.B.11
Hoover, R.S.12
Gamba, G.13
Staub, O.14
-
4
-
-
79955159268
-
Aldosterone paradox: Differential regulation of ion transport in distal nephron
-
Arroyo JP, Ronzaud C, Lagnaz D, Staub O, Gamba G. Aldosterone paradox: differential regulation of ion transport in distal nephron. Physiology (Bethesda) 26: 115-123, 2011.
-
(2011)
Physiology (Bethesda)
, vol.26
, pp. 115-123
-
-
Arroyo, J.P.1
Ronzaud, C.2
Lagnaz, D.3
Staub, O.4
Gamba, G.5
-
5
-
-
83055180555
-
Pathogenesis of pseudohypoaldosteronism type 2 by WNK1 mutations
-
Bergaya S, Vidal-Petiot E, Jeunemaitre X, Hadchouel J. Pathogenesis of pseudohypoaldosteronism type 2 by WNK1 mutations. Curr Opin Nephrol Hypertens 21: 39-45, 2012.
-
(2012)
Curr Opin Nephrol Hypertens
, vol.21
, pp. 39-45
-
-
Bergaya, S.1
Vidal-Petiot, E.2
Jeunemaitre, X.3
Hadchouel, J.4
-
6
-
-
3042694692
-
Nedd4-1-mediated ubiquitination and subsequent recruitment of Tsg101 ensure HTLV-1 Gag trafficking towards the multivesicular body pathway prior to virus budding
-
Blot V, Perugi F, Gay B, Prevost MC, Briant L, Tangy F, Abriel H, Staub O, Dokhelar MC, Pique C. Nedd4-1-mediated ubiquitination and subsequent recruitment of Tsg101 ensure HTLV-1 Gag trafficking towards the multivesicular body pathway prior to virus budding. J Cell Sci 117: 2357-2367, 2004.
-
(2004)
J Cell Sci
, vol.117
, pp. 2357-2367
-
-
Blot, V.1
Perugi, F.2
Gay, B.3
Prevost, M.C.4
Briant, L.5
Tangy, F.6
Abriel, H.7
Staub, O.8
Dokhelar, M.C.9
Pique, C.10
-
7
-
-
84856431125
-
Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities
-
Boyden LM, Choi M, Choate KA, Nelson-Williams CJ, Farhi A, Toka HR, Tikhonova IR, Bjornson R, Mane SM, Colussi G, Lebel M, Gordon RD, Semmekrot BA, Poujol A, Valimaki MJ, De Ferrari ME, Sanjad SA, Gutkin M, Karet FE, Tucci JR, Stockigt JR, Keppler-Noreuil KM, Porter CC, Anand SK, Whiteford ML, Davis ID, Dewar SB, Bettinelli A, Fadrowski JJ, Belsha CW, Hunley TE, Nelson RD, Trachtman H, Cole TR, Pinsk M, Bockenhauer D, Shenoy M, Vaidyanathan P, Foreman JW, Rasoulpour M, Thameem F, Al Shahrouri HZ, Radhakrishnan J, Gharavi AG, Goilav B, Lifton RP. Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. Nature 482: 98-102, 2012.
-
(2012)
Nature
, vol.482
, pp. 98-102
-
-
Boyden, L.M.1
Choi, M.2
Choate, K.A.3
Nelson-Williams, C.J.4
Farhi, A.5
Toka, H.R.6
Tikhonova, I.R.7
Bjornson, R.8
Mane, S.M.9
Colussi, G.10
Lebel, M.11
Gordon, R.D.12
Semmekrot, B.A.13
Poujol, A.14
Valimaki, M.J.15
De Ferrari, M.E.16
Sanjad, S.A.17
Gutkin, M.18
Karet, F.E.19
Tucci, J.R.20
Stockigt, J.R.21
Keppler-Noreuil, K.M.22
Porter, C.C.23
Anand, S.K.24
Whiteford, M.L.25
Davis, I.D.26
Dewar, S.B.27
Bettinelli, A.28
Fadrowski, J.J.29
Belsha, C.W.30
Hunley, T.E.31
Nelson, R.D.32
Trachtman, H.33
Cole, T.R.34
Pinsk, M.35
Bockenhauer, D.36
Shenoy, M.37
Vaidyanathan, P.38
Foreman, J.W.39
Rasoulpour, M.40
Thameem, F.41
Al Shahrouri, H.Z.42
Radhakrishnan, J.43
Gharavi, A.G.44
Goilav, B.45
Lifton, R.P.46
more..
-
8
-
-
33745076253
-
WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells
-
Cai H, Cebotaru V, Wang YH, Zhang XM, Cebotaru L, Guggino SE, Guggino WB. WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells. Kidney Int 69: 2162-2170, 2006.
-
(2006)
Kidney Int
, vol.69
, pp. 2162-2170
-
-
Cai, H.1
Cebotaru, V.2
Wang, Y.H.3
Zhang, X.M.4
Cebotaru, L.5
Guggino, S.E.6
Guggino, W.B.7
-
9
-
-
80054809149
-
Neural precursor cell-expressed developmentally down-regulated protein 4-2 (Nedd4-2) regulation by 14-3-3 protein binding at canonical serum and glucocorticoid kinase 1 (SGK1) phosphorylation sites
-
Chandran S, Li H, Dong W, Krasinska K, Adams C, Alexandrova L, Chien A, Hallows KR, Bhalla V. Neural precursor cell-expressed developmentally down-regulated protein 4-2 (Nedd4-2) regulation by 14-3-3 protein binding at canonical serum and glucocorticoid kinase 1 (SGK1) phosphorylation sites. J Biol Chem 286: 37830-37840, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 37830-37840
-
-
Chandran, S.1
Li, H.2
Dong, W.3
Krasinska, K.4
Adams, C.5
Alexandrova, L.6
Chien, A.7
Hallows, K.R.8
Bhalla, V.9
-
10
-
-
18244392958
-
+ channel cell surface expression
-
+ channel cell surface expression. EMBO J 20: 7052-7059, 2001.
-
(2001)
EMBO J
, vol.20
, pp. 7052-7059
-
-
Debonneville, C.1
Flores, S.Y.2
Kamynina, E.3
Plant, P.J.4
Tauxe, C.5
Thomas, M.A.6
Munster, C.7
Chraibi, A.8
Pratt, J.H.9
Horisberger, J.D.10
Pearce, D.11
Loffing, J.12
Staub, O.13
-
11
-
-
32444437942
-
WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway
-
De Los Heros P, Kahle KT, Rinehart J, Bobadilla NA, Vazquez N, San Cristobal P, Mount DB, Lifton RP, Hebert SC, Gamba G. WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway. Proc Natl Acad Sci USA 103: 1976-1981, 2006.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1976-1981
-
-
De Los Heros, P.1
Kahle, K.T.2
Rinehart, J.3
Bobadilla, N.A.4
Vazquez, N.5
San Cristobal, P.6
Mount, D.B.7
Lifton, R.P.8
Hebert, S.C.9
Gamba, G.10
-
12
-
-
1242351817
-
Characterization of a murine renal distal convoluted tubule cell line for the study of transcellular calcium transport
-
Diepens RJ, den Dekker E, Bens M, Weidema AF, Vandewalle A, Bindels RJ, Hoenderop JG. Characterization of a murine renal distal convoluted tubule cell line for the study of transcellular calcium transport. Am J Physiol Renal Physiol 286: F483-F489, 2004.
-
(2004)
Am J Physiol Renal Physiol
, vol.286
-
-
Diepens, R.J.1
den Dekker, E.2
Bens, M.3
Weidema, A.F.4
Vandewalle, A.5
Bindels, R.J.6
Hoenderop, J.G.7
-
13
-
-
84868124507
-
Differential ubiquitylation of the mineralocorticoid receptor is regulated by phosphorylation
-
Faresse N, Vitagliano JJ, Staub O. Differential ubiquitylation of the mineralocorticoid receptor is regulated by phosphorylation. FASEB J 26: 4373-4382, 2012.
-
(2012)
FASEB J
, vol.26
, pp. 4373-4382
-
-
Faresse, N.1
Vitagliano, J.J.2
Staub, O.3
-
14
-
-
28144461773
-
+ transport in cortical collecting duct cells
-
+ transport in cortical collecting duct cells. J Am Soc Nephrol 16: 2279-2287, 2005.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 2279-2287
-
-
Flores, S.Y.1
Loffing-Cueni, D.2
Kamynina, E.3
Daidie, D.4
Gerbex, C.5
Chabanel, S.6
Dudler, J.7
Loffing, J.8
Staub, O.9
-
15
-
-
84871261905
-
- cotransporter by phosphorylation and ubiquitylation
-
- cotransporter by phosphorylation and ubiquitylation. Am J Physiol Renal Physiol 303: F1573-F1583, 2012.
-
(2012)
Am J Physiol Renal Physiol
, vol.303
-
-
Gamba, G.1
-
16
-
-
70349651260
-
- cotransporter: Molecular biology, functional properties, and regulation by WNKs
-
- cotransporter: molecular biology, functional properties, and regulation by WNKs. Am J Physiol Renal Physiol 297: F838-F848, 2009.
-
(2009)
Am J Physiol Renal Physiol
, vol.297
-
-
Gamba, G.1
-
18
-
-
67449090606
-
Renal and brain isoforms of WNK3 have opposite effects on NCCT expression
-
Glover M, Zuber AM, O'Shaughnessy KM. Renal and brain isoforms of WNK3 have opposite effects on NCCT expression. J Am Soc Nephrol 20: 1314-1322, 2009.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 1314-1322
-
-
Glover, M.1
Zuber, A.M.2
O'Shaughnessy, K.M.3
-
19
-
-
33845361061
-
Regulation of the expression of the Na/Cl cotransporter (NCCT) by WNK4 and WNK1: Evidence that accelerated dynamindependent endocytosis is not involved
-
Golbang AP, Cope G, Hamad A, Murthy M, Liu CH, Cuthbert AW, O'Shaughnessy KM. Regulation of the expression of the Na/Cl cotransporter (NCCT) by WNK4 and WNK1: evidence that accelerated dynamindependent endocytosis is not involved. Am J Physiol Renal Physiol 291: F1369-F1376, 2006.
-
(2006)
Am J Physiol Renal Physiol
, vol.291
-
-
Golbang, A.P.1
Cope, G.2
Hamad, A.3
Murthy, M.4
Liu, C.H.5
Cuthbert, A.W.6
O'Shaughnessy, K.M.7
-
20
-
-
0023039605
-
Syndrome of hypertension and hyperkalemia with normal glomerular filtration rate
-
Gordon RD. Syndrome of hypertension and hyperkalemia with normal glomerular filtration rate. Hypertension 8: 93-102, 1986.
-
(1986)
Hypertension
, vol.8
, pp. 93-102
-
-
Gordon, R.D.1
-
21
-
-
0022571505
-
The syndrome of hypertension and hyperkalaemia without renal failure: Long term correction by thiazide diuretic
-
Gordon RD, Hodsman GP. The syndrome of hypertension and hyperkalaemia without renal failure: long term correction by thiazide diuretic. Scott Med J 31: 43-44, 1986.
-
(1986)
Scott Med J
, vol.31
, pp. 43-44
-
-
Gordon, R.D.1
Hodsman, G.P.2
-
22
-
-
78149239779
-
Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension
-
Hadchouel J, Soukaseum C, Busst C, Zhou XO, Baudrie V, Zurrer T, Cambillau M, Elghozi JL, Lifton RP, Loffing J, Jeunemaitre X. Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension. Proc Natl Acad Sci USA 107: 18109-18114, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 18109-18114
-
-
Hadchouel, J.1
Soukaseum, C.2
Busst, C.3
Zhou, X.O.4
Baudrie, V.5
Zurrer, T.6
Cambillau, M.7
Elghozi, J.L.8
Lifton, R.P.9
Loffing, J.10
Jeunemaitre, X.11
-
23
-
-
0029586683
-
A de novo missense mutation of the·subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity
-
Hansson JH, Shild L, Lu Y, Wilson TA, Gautshi I, Shimkets R, Nelson-Williams C, Rossier BC, Lifton RP. A de novo missense mutation of the·subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity. Proc Natl Acad Sci USA 92: 11495-11499, 1995.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 11495-11499
-
-
Hansson, J.H.1
Shild, L.2
Lu, Y.3
Wilson, T.A.4
Gautshi, I.5
Shimkets, R.6
Nelson-Williams, C.7
Rossier, B.C.8
Lifton, R.P.9
-
24
-
-
0028907874
-
A family of proteins structurally and functionally related to the E6-AP ubiquitinprotein ligase
-
Huibregtse JM, Scheffner M, Beaudenon S, Howley PM. A family of proteins structurally and functionally related to the E6-AP ubiquitinprotein ligase. Proc Natl Acad Sci USA 92: 5249, 1995.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5249
-
-
Huibregtse, J.M.1
Scheffner, M.2
Beaudenon, S.3
Howley, P.M.4
-
25
-
-
28044473649
-
- in and out of cells: Implications for control of cell volume and neuronal excitability
-
- in and out of cells: Implications for control of cell volume and neuronal excitability. Proc Natl Acad Sci USA 102: 16783-16788, 2005.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 16783-16788
-
-
Kahle, K.T.1
Rinehart, J.2
De Los Heros, P.3
Louvi, A.4
Meade, P.5
Vazquez, N.6
Hebert, S.C.7
Gamba, G.8
Gimenez, I.9
Lifton, R.P.10
-
26
-
-
0345659215
-
+ secretion
-
+ secretion. Nat Genet 35: 372-376, 2003.
-
(2003)
Nat Genet
, vol.35
, pp. 372-376
-
-
Kahle, K.T.1
Wilson, F.H.2
Leng, Q.3
Lalioti, M.D.4
O'Connell, A.D.5
Dong, K.6
Rapson, A.K.7
McGregor, G.G.8
Giebisch, G.9
Hebert, S.C.10
Lifton, R.P.11
-
27
-
-
0037108887
-
Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search
-
Keller A, Nesvizhskii AI, Kolker E, Aebersold R. Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal Chem 74: 5383-5392, 2002.
-
(2002)
Anal Chem
, vol.74
, pp. 5383-5392
-
-
Keller, A.1
Nesvizhskii, A.I.2
Kolker, E.3
Aebersold, R.4
-
28
-
-
0032564369
-
The thiazide-sensitive Na-Cl cotransporter is an aldosterone-induced protein
-
Kim GH, Masilamani S, Turner R, Mitchell C, Wade JB, Knepper MA. The thiazide-sensitive Na-Cl cotransporter is an aldosterone-induced protein. Proc Natl Acad Sci USA 95: 14552-14557, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14552-14557
-
-
Kim, G.H.1
Masilamani, S.2
Turner, R.3
Mitchell, C.4
Wade, J.B.5
Knepper, M.A.6
-
29
-
-
77955395818
-
RasGRP1 stimulation enhances ubiquitination and endocytosis of the sodium-chloride cotransporter
-
Ko B, Kamsteeg EJ, Cooke LL, Moddes LN, Deen PM, Hoover RS. RasGRP1 stimulation enhances ubiquitination and endocytosis of the sodium-chloride cotransporter. Am J Physiol Renal Physiol 299: F300-F309, 2010.
-
(2010)
Am J Physiol Renal Physiol
, vol.299
-
-
Ko, B.1
Kamsteeg, E.J.2
Cooke, L.L.3
Moddes, L.N.4
Deen, P.M.5
Hoover, R.S.6
-
30
-
-
33749118898
-
Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule
-
Lalioti MD, Zhang J, Volkman HM, Kahle KT, Hoffmann KE, Toka HR, Nelson-Williams C, Ellison DH, Flavell R, Booth CJ, Lu Y, Geller DS, Lifton RP. Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule. Nat Genet 38: 1124-1132, 2006.
-
(2006)
Nat Genet
, vol.38
, pp. 1124-1132
-
-
Lalioti, M.D.1
Zhang, J.2
Volkman, H.M.3
Kahle, K.T.4
Hoffmann, K.E.5
Toka, H.R.6
Nelson-Williams, C.7
Ellison, D.H.8
Flavell, R.9
Booth, C.J.10
Lu, Y.11
Geller, D.S.12
Lifton, R.P.13
-
31
-
-
33645901817
-
+ channel ROMK1 (Kir1. 1)
-
+ channel ROMK1 (Kir1. 1). J Physiol 571: 275-286, 2006.
-
(2006)
J Physiol
, vol.571
, pp. 275-286
-
-
Leng, Q.1
Kahle, K.T.2
Rinehart, J.3
McGregor, G.G.4
Wilson, F.H.5
Canessa, C.M.6
Lifton, R.P.7
Hebert, S.C.8
-
32
-
-
84859425383
-
KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron
-
Louis-Dit-Picard H, Barc J, Trujillano D, Miserey-Lenkei S, Bouatia-Naji N, Pylypenko O, Beaurain G, Bonnefond A, Sand O, Simian C, Vidal-Petiot E, Soukaseum C, Mandet C, Broux F, Chabre O, Delahousse M, Esnault V, Fiquet B, Houillier P, Bagnis CI, Koenig J, Konrad M, Landais P, Mourani C, Niaudet P, Probst V, Thauvin C, Unwin RJ, Soroka SD, Ehret G, Ossowski S., Caulfield M., Bruneval P, Estivill X, Froguel P, Hadchouel J, Schott JJ, and Jeunemaitre X. KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron. Nat Genet 44: 456-460, 2012.
-
(2012)
Nat Genet
, vol.44
, pp. 456-460
-
-
Louis-Dit-Picard, H.1
Barc, J.2
Trujillano, D.3
Miserey-Lenkei, S.4
Bouatia-Naji, N.5
Pylypenko, O.6
Beaurain, G.7
Bonnefond, A.8
Sand, O.9
Simian, C.10
Vidal-Petiot, E.11
Soukaseum, C.12
Mandet, C.13
Broux, F.14
Chabre, O.15
Delahousse, M.16
Esnault, V.17
Fiquet, B.18
Houillier, P.19
Bagnis, C.I.20
Koenig, J.21
Konrad, M.22
Landais, P.23
Mourani, C.24
Niaudet, P.25
Probst, V.26
Thauvin, C.27
Unwin, R.J.28
Soroka, S.D.29
Ehret, G.30
Ossowski, S.31
Caulfield, M.32
Bruneval, P.33
Estivill, X.34
Froguel, P.35
Hadchouel, J.36
Schott, J.J.37
Jeunemaitre, X.38
more..
-
33
-
-
0036328423
-
Pseudohypoaldosteronism type II: Marked sensitivity to thiazides, hypercalciuria, normomagnesemia, and low bone mineral density
-
Mayan H, Vered I, Mouallem M, Tzadok-Witkon M, Pauzner R, Farfel Z. Pseudohypoaldosteronism type II: marked sensitivity to thiazides, hypercalciuria, normomagnesemia, and low bone mineral density. J Clin Endocrinol Metab 87: 3248-3254, 2002.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 3248-3254
-
-
Mayan, H.1
Vered, I.2
Mouallem, M.3
Tzadok-Witkon, M.4
Pauzner, R.5
Farfel, Z.6
-
34
-
-
78751654853
-
The WNKs: Atypical protein kinases with pleiotropic actions
-
McCormick JA, Ellison DH. The WNKs: atypical protein kinases with pleiotropic actions. Physiol Rev 91: 177-219, 2011.
-
(2011)
Physiol Rev
, vol.91
, pp. 177-219
-
-
McCormick, J.A.1
Ellison, D.H.2
-
35
-
-
83155181580
-
Overexpression of the sodium chloride cotransporter is not sufficient to cause familial hyperkalemic hypertension
-
McCormick JA, Nelson JH, Yang CL, Curry JN, Ellison DH. Overexpression of the sodium chloride cotransporter is not sufficient to cause familial hyperkalemic hypertension. Hypertension 58: 888-894, 2011.
-
(2011)
Hypertension
, vol.58
, pp. 888-894
-
-
McCormick, J.A.1
Nelson, J.H.2
Yang, C.L.3
Curry, J.N.4
Ellison, D.H.5
-
36
-
-
84878563368
-
Loss of WNK3 is compensated for by the WNK1/SPAK axis in the kidney of the mouse
-
Mederle K, Mutig K, Paliege A, Carota I, Bachmann S, Castrop H, Oppermann M. Loss of WNK3 is compensated for by the WNK1/SPAK axis in the kidney of the mouse. Am J Physiol Renal Physiol 304: F1198-F1209, 2013.
-
(2013)
Am J Physiol Renal Physiol
, vol.304
-
-
Mederle, K.1
Mutig, K.2
Paliege, A.3
Carota, I.4
Bachmann, S.5
Castrop, H.6
Oppermann, M.7
-
38
-
-
1942469338
-
- cotransporter and reveals a role for transmembrane segment 4 in chloride and thiazide affinity
-
- cotransporter and reveals a role for transmembrane segment 4 in chloride and thiazide affinity. J Biol Chem 279: 16553-16560, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 16553-16560
-
-
Moreno, E.1
Tovar-Palacio, C.2
De Los Heros, P.3
Guzman, B.4
Bobadilla, N.A.5
Vazquez, N.6
Riccardi, D.7
Poch, E.8
Gamba, G.9
-
39
-
-
85027925594
-
Epigenetic modulation of the renal beta-adrenergic-WNK4 pathway in salt-sensitive hypertension
-
Mu S, Shimosawa T, Ogura S, Wang H, Uetake Y, Kawakami-Mori F, Marumo T, Yatomi Y, Geller DS, Tanaka H, Fujita T. Epigenetic modulation of the renal beta-adrenergic-WNK4 pathway in salt-sensitive hypertension. Nat Med 17: 573-581, 2011.
-
(2011)
Nat Med
, vol.17
, pp. 573-581
-
-
Mu, S.1
Shimosawa, T.2
Ogura, S.3
Wang, H.4
Uetake, Y.5
Kawakami-Mori, F.6
Marumo, T.7
Yatomi, Y.8
Geller, D.S.9
Tanaka, H.10
Fujita, T.11
-
40
-
-
77649103887
-
- cotransporter by vasopressin involves phosphorylation and membrane translocation
-
- cotransporter by vasopressin involves phosphorylation and membrane translocation. Am J Physiol Renal Physiol 298: F502-F509, 2010.
-
(2010)
Am J Physiol Renal Physiol
, vol.298
-
-
Mutig, K.1
Saritas, T.2
Uchida, S.3
Kahl, T.4
Borowski, T.5
Paliege, A.6
Bihlick, A.7
Bleich, M.8
Shan, Q.9
Bachmann, S.10
-
41
-
-
0042338362
-
A statistical model for identifying proteins by tandem mass spectrometry
-
Nesvizhskii AI, Keller A, Kolker E, Aebersold R. A statistical model for identifying proteins by tandem mass spectrometry. Anal Chem 75: 4646-4658, 2003.
-
(2003)
Anal Chem
, vol.75
, pp. 4646-4658
-
-
Nesvizhskii, A.I.1
Keller, A.2
Kolker, E.3
Aebersold, R.4
-
42
-
-
84875158737
-
The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: Disease-causing mutations in KLHL3 and WNK4 disrupt interaction
-
Ohta A, Schumacher FR, Mehellou Y, Johnson C, Knebel A, Macartney TJ, Wood NT, Alessi DR, Kurz T. The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction. Biochem J 451: 111-122, 2013.
-
(2013)
Biochem J
, vol.451
, pp. 111-122
-
-
Ohta, A.1
Schumacher, F.R.2
Mehellou, Y.3
Johnson, C.4
Knebel, A.5
Macartney, T.J.6
Wood, N.T.7
Alessi, D.R.8
Kurz, T.9
-
43
-
-
84964677935
-
A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo
-
Oi K, Sohara E, Rai T, Misawa M, Chiga M, Alessi DR, Sasaki S, Uchida S. A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo. Biol Open 1: 120-127, 2012.
-
(2012)
Biol Open
, vol.1
, pp. 120-127
-
-
Oi, K.1
Sohara, E.2
Rai, T.3
Misawa, M.4
Chiga, M.5
Alessi, D.R.6
Sasaki, S.7
Uchida, S.8
-
44
-
-
33749386424
-
The Na-Cl cotransporter is activated and phosphorylated at the amino terminal domain upon intracellular chloride depletion
-
Pacheco-Alvarez D, San Cristobal P, Meade P, Moreno E, Vazquez N, Munoz E, Diaz A, Juarez ME, Gimenez I, Gamba G. The Na-Cl cotransporter is activated and phosphorylated at the amino terminal domain upon intracellular chloride depletion. J Biol Chem 281: 28755-28763, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 28755-28763
-
-
Pacheco-Alvarez, D.1
San Cristobal, P.2
Meade, P.3
Moreno, E.4
Vazquez, N.5
Munoz, E.6
Diaz, A.7
Juarez, M.E.8
Gimenez, I.9
Gamba, G.10
-
45
-
-
84858205722
-
WNK3-SPAK interaction is required for the modulation of NCC and other members of the SLC12 family
-
Pacheco-Alvarez D, Vazquez N, Castaneda-Bueno M, de los Heros P, Cortes-Gonzalez C, Moreno E, Meade P, Bobadilla NA, Gamba G. WNK3-SPAK interaction is required for the modulation of NCC and other members of the SLC12 family. Cell Physiol Biochem 29: 291-302, 2012.
-
(2012)
Cell Physiol Biochem
, vol.29
, pp. 291-302
-
-
Pacheco-Alvarez, D.1
Vazquez, N.2
Castaneda-Bueno, M.3
de los Heros, P.4
Cortes-Gonzalez, C.5
Moreno, E.6
Meade, P.7
Bobadilla, N.A.8
Gamba, G.9
-
46
-
-
77954243057
-
Vasopressin induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter in the distal convoluted tubule
-
Pedersen NB, Hofmeister MV, Rosenbaek LL, Nielsen J, Fenton RA. Vasopressin induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter in the distal convoluted tubule. Kidney Int 78: 160-169, 2010.
-
(2010)
Kidney Int
, vol.78
, pp. 160-169
-
-
Pedersen, N.B.1
Hofmeister, M.V.2
Rosenbaek, L.L.3
Nielsen, J.4
Fenton, R.A.5
-
47
-
-
84896832136
-
Protein phosphatase 1 inhibitor-1 deficiency reduces phosphorylation of renal NaCl cotransporter and causes arterial hypotension
-
Picard N, Trompf K, Yang CL, Miller RL, Carrel M, Loffing-Cueni D, Fenton RA, Ellison DH, Loffing J. Protein phosphatase 1 inhibitor-1 deficiency reduces phosphorylation of renal NaCl cotransporter and causes arterial hypotension. J Am Soc Nephrol 25: 511-522, 2014.
-
(2014)
J Am Soc Nephrol
, vol.25
, pp. 511-522
-
-
Picard, N.1
Trompf, K.2
Yang, C.L.3
Miller, R.L.4
Carrel, M.5
Loffing-Cueni, D.6
Fenton, R.A.7
Ellison, D.H.8
Loffing, J.9
-
48
-
-
46149116565
-
Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases
-
Ponce-Coria J, San Cristobal P, Kahle KT, Vazquez N, Pacheco-Alvarez D, De Los Heros P, Juarez P, Munoz E, Michel G, Bobadilla NA, Gimenez I, Lifton RP, Hebert SC, Gamba G. Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases. Proc Natl Acad Sci USA 105: 8458-8463, 2008.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 8458-8463
-
-
Ponce-Coria, J.1
San Cristobal, P.2
Kahle, K.T.3
Vazquez, N.4
Pacheco-Alvarez, D.5
De Los Heros, P.6
Juarez, P.7
Munoz, E.8
Michel, G.9
Bobadilla, N.A.10
Gimenez, I.11
Lifton, R.P.12
Hebert, S.C.13
Gamba, G.14
-
49
-
-
56349151939
-
The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway
-
Richardson C, Alessi DR. The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway. J Cell Sci 121: 3293-3304, 2008.
-
(2008)
J Cell Sci
, vol.121
, pp. 3293-3304
-
-
Richardson, C.1
Alessi, D.R.2
-
50
-
-
42149175531
-
- cotransporter by the WNK-regulated kinases SPAK and OSR1
-
- cotransporter by the WNK-regulated kinases SPAK and OSR1. J Cell Sci 121: 675-684, 2008.
-
(2008)
J Cell Sci
, vol.121
, pp. 675-684
-
-
Richardson, C.1
Rafiqi, F.H.2
Karlsson, H.K.3
Moleleki, N.4
Vandewalle, A.5
Campbell, D.G.6
Morrice, N.A.7
Alessi, D.R.8
-
51
-
-
28044458544
-
- cotransporters required for normal blood pressure homeostasis
-
- cotransporters required for normal blood pressure homeostasis. Proc Natl Acad Sci USA 102: 16777-16782, 2005.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 16777-16782
-
-
Rinehart, J.1
Kahle, K.T.2
De Los Heros, P.3
Vazquez, N.4
Meade, P.5
Wilson, F.H.6
Hebert, S.C.7
Gimenez, I.8
Gamba, G.9
Lifton, R.P.10
-
52
-
-
80051937272
-
WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters
-
Rinehart J, Vazquez N, Kahle KT, Hodson CA, Ring AM, Gulcicek EE, Louvi A, Bobadilla NA, Gamba G, Lifton RP. WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters. J Biol Chem 286: 30171-30180, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 30171-30180
-
-
Rinehart, J.1
Vazquez, N.2
Kahle, K.T.3
Hodson, C.A.4
Ring, A.M.5
Gulcicek, E.E.6
Louvi, A.7
Bobadilla, N.A.8
Gamba, G.9
Lifton, R.P.10
-
53
-
-
34247236088
-
+ homeostasis
-
+ homeostasis. Proc Natl Acad Sci US A 104: 4025-4029, 2007.
-
(2007)
Proc Natl Acad Sci US A
, vol.104
, pp. 4025-4029
-
-
Ring, A.M.1
Leng, Q.2
Rinehart, J.3
Wilson, F.H.4
Kahle, K.T.5
Hebert, S.C.6
Lifton, R.P.7
-
54
-
-
84873350794
-
Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension
-
Ronzaud C, Loffing-Cueni D, Hausel P, Debonneville A, Malsure SR, Fowler-Jaeger N, Boase NA, Perrier R, Maillard M, Yang B, Stokes JB, Koesters R, Kumar S, Hummler E, Loffing J, Staub O. Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension. J Clin Invest 123: 657-665, 2013.
-
(2013)
J Clin Invest
, vol.123
, pp. 657-665
-
-
Ronzaud, C.1
Loffing-Cueni, D.2
Hausel, P.3
Debonneville, A.4
Malsure, S.R.5
Fowler-Jaeger, N.6
Boase, N.A.7
Perrier, R.8
Maillard, M.9
Yang, B.10
Stokes, J.B.11
Koesters, R.12
Kumar, S.13
Hummler, E.14
Loffing, J.15
Staub, O.16
-
55
-
-
55749101582
-
Deubiquitylation regulates activation and proteolytic cleavage of ENaC
-
Ruffieux-Daidie D, Poirot O, Boulkroun S, Verrey F, Kellenberger S, Staub O. Deubiquitylation regulates activation and proteolytic cleavage of ENaC. J Am Soc Nephrol 19: 2170-2180, 2008.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 2170-2180
-
-
Ruffieux-Daidie, D.1
Poirot, O.2
Boulkroun, S.3
Verrey, F.4
Kellenberger, S.5
Staub, O.6
-
56
-
-
63149133727
-
Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway
-
San Cristobal P, Pacheco-Alvarez D, Richardson C, Ring AM, Vazquez N, Rafiqi FH, Chari D, Kahle KT, Leng Q, Bobadilla NA, Hebert SC, Alessi DR, Lifton RP, Gamba G. Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway. Proc Natl Acad Sci USA 106: 4384-4389, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 4384-4389
-
-
San Cristobal, P.1
Pacheco-Alvarez, D.2
Richardson, C.3
Ring, A.M.4
Vazquez, N.5
Rafiqi, F.H.6
Chari, D.7
Kahle, K.T.8
Leng, Q.9
Bobadilla, N.A.10
Hebert, S.C.11
Alessi, D.R.12
Lifton, R.P.13
Gamba, G.14
-
58
-
-
34548604273
-
Angiotensin II provokes acute trafficking of distal tubule NaCl cotransporter (NCC) to apical membrane
-
Sandberg MB, Riquier AD, Pihakaski-Maunsbach K, McDonough AA, Maunsbach AB. Angiotensin II provokes acute trafficking of distal tubule NaCl cotransporter (NCC) to apical membrane. Am J Physiol Renal Physiol 293: F662-F669, 2007.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
-
-
Sandberg, M.B.1
Riquier, A.D.2
Pihakaski-Maunsbach, K.3
McDonough, A.A.4
Maunsbach, A.B.5
-
59
-
-
0029927505
-
Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels
-
Shevchenko A, Wilm M, Vorm O, Mann M. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 68: 850-858, 1996.
-
(1996)
Anal Chem
, vol.68
, pp. 850-858
-
-
Shevchenko, A.1
Wilm, M.2
Vorm, O.3
Mann, M.4
-
60
-
-
84877340391
-
Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4
-
Shibata S, Zhang J, Puthumana J, Stone KL, Lifton RP. Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4. Proc Natl Acad Sci USA 110: 7838-7843, 2013.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 7838-7843
-
-
Shibata, S.1
Zhang, J.2
Puthumana, J.3
Stone, K.L.4
Lifton, R.P.5
-
61
-
-
0027946089
-
Liddle's syndrome: Heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel
-
Shimkets RA, Warnock DG, Bositis CM, Nelson-Williamns C, Hansson JH, Schambelan M, Gill JR, Ulick S, Milora RV, Findling JW, Canessa CM, Rossier BC, Lifton RP. Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel. Cell 79: 407-414, 1994.
-
(1994)
Cell
, vol.79
, pp. 407-414
-
-
Shimkets, R.A.1
Warnock, D.G.2
Bositis, C.M.3
Nelson-Williamns, C.4
Hansson, J.H.5
Schambelan, M.6
Gill, J.R.7
Ulick, S.8
Milora, R.V.9
Findling, J.W.10
Canessa, C.M.11
Rossier, B.C.12
Lifton, R.P.13
-
62
-
-
9044235777
-
Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazidesensitive Na-Cl cotransporter
-
Simon DB, Nelson-Williams C, Johnson-Bia M, Ellison D, Karet FE, Morey-Molina A, Vaara I, Iwata F, Cushner HM, Koolen M, Gainza FJ, Gitelman HJ, Lifton RP. Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazidesensitive Na-Cl cotransporter. Nat Genet 12: 24-30, 1996.
-
(1996)
Nat Genet
, vol.12
, pp. 24-30
-
-
Simon, D.B.1
Nelson-Williams, C.2
Johnson-Bia, M.3
Ellison, D.4
Karet, F.E.5
Morey-Molina, A.6
Vaara, I.7
Iwata, F.8
Cushner, H.M.9
Koolen, M.10
Gainza, F.J.11
Gitelman, H.J.12
Lifton, R.P.13
-
65
-
-
0001620648
-
+ channel by Nedd4 and ubiquitination
-
+ channel by Nedd4 and ubiquitination. Kidney Int 57: 809-815, 2000.
-
(2000)
Kidney Int
, vol.57
, pp. 809-815
-
-
Staub, O.1
Abriel, H.2
Plant, P.3
Ishikawa, T.4
Kanelis, V.5
Saleki, R.6
Horisberger, J.D.7
Schild, L.8
Rotin, D.9
-
66
-
-
0029874436
-
+ channel deleted in Liddle's syndrome
-
+ channel deleted in Liddle's syndrome. EMBO J 15: 2371-2380, 1996.
-
(1996)
EMBO J
, vol.15
, pp. 2371-2380
-
-
Staub, O.1
Dho, S.2
Henry, P.C.3
Correa, J.4
Ishikawa, T.5
McGlade, J.6
Rotin, D.7
-
67
-
-
67650533826
-
WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction
-
Subramanya AR, Liu J, Ellison DH, Wade JB, Welling PA. WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction. J Biol Chem 284: 18471-18480, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 18471-18480
-
-
Subramanya, A.R.1
Liu, J.2
Ellison, D.H.3
Wade, J.B.4
Welling, P.A.5
-
69
-
-
84055219428
-
SPAK/OSR1 regulate NKCC1 and WNK activity: Analysis of WNK isoform interactions and activation by T-loop transautophosphorylation
-
Thastrup JO, Rafiqi FH, Vitari AC, Pozo-Guisado E, Deak M, Mehellou Y, Alessi DR. SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop transautophosphorylation. Biochem J 441: 325-337, 2012.
-
(2012)
Biochem J
, vol.441
, pp. 325-337
-
-
Thastrup, J.O.1
Rafiqi, F.H.2
Vitari, A.C.3
Pozo-Guisado, E.4
Deak, M.5
Mehellou, Y.6
Alessi, D.R.7
-
70
-
-
4043059200
-
Cardiac voltage-gated sodium channel Nav1. 5 is regulated by Nedd4-2 mediated ubiquitination
-
van Bemmelen MX, Rougier JS, Gavillet B, Apotheloz F, Daidie D, Tateyama M, Rivolta I, Thomas MA, Kass RS, Staub O, Abriel H. Cardiac voltage-gated sodium channel Nav1. 5 is regulated by Nedd4-2 mediated ubiquitination. Circ Res 95: 284-291, 2004.
-
(2004)
Circ Res
, vol.95
, pp. 284-291
-
-
van Bemmelen, M.X.1
Rougier, J.S.2
Gavillet, B.3
Apotheloz, F.4
Daidie, D.5
Tateyama, M.6
Rivolta, I.7
Thomas, M.A.8
Kass, R.S.9
Staub, O.10
Abriel, H.11
-
71
-
-
85027955816
-
Angiotensin II induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter independent of aldosterone
-
van der Lubbbe N, Lim CH, Fenton RA, Meima ME, Jan Danser AH, Zietse R, Hoorn EJ. Angiotensin II induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter independent of aldosterone. Kidney Int 79: 66-76, 2011.
-
(2011)
Kidney Int
, vol.79
, pp. 66-76
-
-
van der Lubbbe, N.1
Lim, C.H.2
Fenton, R.A.3
Meima, M.E.4
Jan Danser, A.H.5
Zietse, R.6
Hoorn, E.J.7
-
73
-
-
84883403721
-
WNK1-related familial hyperkalemic hypertension results from an increased expression of L-WNK1 specifically in the distal nephron
-
Vidal-Petiot E, Elvira-Matelot E, Mutig K, Soukaseum C, Baudrie V, Wu S, Cheval L, Huc E, Cambillau M, Bachmann S, Doucet A, Jeunemaitre X, Hadchouel J. WNK1-related familial hyperkalemic hypertension results from an increased expression of L-WNK1 specifically in the distal nephron. Proc Natl Acad Sci USA 110: 14366-14371, 2013.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 14366-14371
-
-
Vidal-Petiot, E.1
Elvira-Matelot, E.2
Mutig, K.3
Soukaseum, C.4
Baudrie, V.5
Wu, S.6
Cheval, L.7
Huc, E.8
Cambillau, M.9
Bachmann, S.10
Doucet, A.11
Jeunemaitre, X.12
Hadchouel, J.13
-
74
-
-
0030026070
-
Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry
-
Wilm M, Shevchenko A, Houthaeve T, Breit S, Schweigerer L, Fotsis T, Mann M. Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry. Nature 379: 466-469, 1996.
-
(1996)
Nature
, vol.379
, pp. 466-469
-
-
Wilm, M.1
Shevchenko, A.2
Houthaeve, T.3
Breit, S.4
Schweigerer, L.5
Fotsis, T.6
Mann, M.7
-
75
-
-
17944373014
-
Human hypertension caused by mutations in WNK kinases
-
Wilson FH, Disse-Nicodeme S, Choate KA, Ishikawa K, Nelson-Williams C, Desitter I, Gunel M, Milford DV, Lipkin GW, Achard JM, Feely MP, Dussol B, Berland Y, Unwin RJ, Mayan H, Simon DB, Farfel Z, Jeunemaitre X, Lifton RP. Human hypertension caused by mutations in WNK kinases. Science 293: 1107-1112, 2001.
-
(2001)
Science
, vol.293
, pp. 1107-1112
-
-
Wilson, F.H.1
Disse-Nicodeme, S.2
Choate, K.A.3
Ishikawa, K.4
Nelson-Williams, C.5
Desitter, I.6
Gunel, M.7
Milford, D.V.8
Lipkin, G.W.9
Achard, J.M.10
Feely, M.P.11
Dussol, B.12
Berland, Y.13
Unwin, R.J.14
Mayan, H.15
Simon, D.B.16
Farfel, Z.17
Jeunemaitre, X.18
Lifton, R.P.19
-
76
-
-
0037457965
-
Molecular pathogenesis of inherited hypertension with hyperkalemia: The Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4
-
Wilson FH, Kahle KT, Sabath E, Lalioti MD, Rapson AK, Hoover RS, Hebert SC, Gamba G, Lifton RP. Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4. Proc Natl Acad Sci USA 100: 680-684, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 680-684
-
-
Wilson, F.H.1
Kahle, K.T.2
Sabath, E.3
Lalioti, M.D.4
Rapson, A.K.5
Hoover, R.S.6
Hebert, S.C.7
Gamba, G.8
Lifton, R.P.9
-
77
-
-
84878774970
-
Disease-causing mutations in KLHL3 impair its effect on WNK4 degradation
-
Wu G, Peng JB. Disease-causing mutations in KLHL3 impair its effect on WNK4 degradation. FEBS Lett 587: 1717-1722, 2013.
-
(2013)
FEBS Lett
, vol.587
, pp. 1717-1722
-
-
Wu, G.1
Peng, J.B.2
-
78
-
-
0037382807
-
WNK kinases regulate thiazide-sensitive Na-Cl cotransport
-
Yang CL, Angell J, Mitchell R, Ellison DH. WNK kinases regulate thiazide-sensitive Na-Cl cotransport. J Clin Invest 111: 1039-1045, 2003.
-
(2003)
J Clin Invest
, vol.111
, pp. 1039-1045
-
-
Yang, C.L.1
Angell, J.2
Mitchell, R.3
Ellison, D.H.4
-
79
-
-
36048938340
-
The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex
-
Yang CL, Zhu X, Ellison DH. The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex. J Clin Invest 117: 3403-3411, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 3403-3411
-
-
Yang, C.L.1
Zhu, X.2
Ellison, D.H.3
-
80
-
-
18244373189
-
Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport
-
Yang CL, Zhu X, Wang Z, Subramanya AR, Ellison DH. Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport. J Clin Invest 115: 1379-1387, 2005.
-
(2005)
J Clin Invest
, vol.115
, pp. 1379-1387
-
-
Yang, C.L.1
Zhu, X.2
Wang, Z.3
Subramanya, A.R.4
Ellison, D.H.5
-
81
-
-
2442680179
-
SGK1 increases Na, K-ATP cell-surface expression and function in Xenopus laevis oocytes
-
Zecevic M, Heitzmann D, Camargo SM, Verrey F. SGK1 increases Na, K-ATP cell-surface expression and function in Xenopus laevis oocytes. Pflügers Arch 448: 29-35, 2004.
-
(2004)
Pflügers Arch
, vol.448
, pp. 29-35
-
-
Zecevic, M.1
Heitzmann, D.2
Camargo, S.M.3
Verrey, F.4
-
82
-
-
75149175239
-
WNK4 enhances the degradation of NCC through a sortilin-mediated lysosomal pathway
-
Zhou B, Zhuang J, Gu D, Wang H, Cebotaru L, Guggino WB, Cai H. WNK4 enhances the degradation of NCC through a sortilin-mediated lysosomal pathway. J Am Soc Nephrol 21: 82-92, 2010.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 82-92
-
-
Zhou, B.1
Zhuang, J.2
Gu, D.3
Wang, H.4
Cebotaru, L.5
Guggino, W.B.6
Cai, H.7
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