메뉴 건너뛰기




Volumn 29, Issue 1-2, 2012, Pages 291-302

WNK3-SPAK interaction is required for the modulation of NCC and other members of the SLC12 family

Author keywords

Distal tubule; Hypertension; Salt transport; Thiazide; WNK

Indexed keywords

BETA ACTIN; CHLORIDE; MUTANT PROTEIN; PHOSPHOTRANSFERASE; POTASSIUM CHLORIDE COTRANSPORTER 4; PROTEIN SLC12; PROTEIN SPAK; PROTEIN WNK3; SODIUM CHLORIDE COTRANSPORTER; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 1; THREONINE; UNCLASSIFIED DRUG;

EID: 84858205722     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000337610     Document Type: Article
Times cited : (30)

References (38)
  • 1
    • 15544384004 scopus 로고    scopus 로고
    • Molecular physiology and pathophysiology of the electroneutral cation-chloride cotransporters
    • Gamba G: Molecular physiology and pathophysiology of the electroneutral cation-chloride cotransporters. Physiol Rev 2005;85:423-493.
    • (2005) Physiol Rev , vol.85 , pp. 423-493
    • Gamba, G.1
  • 2
    • 8644288484 scopus 로고    scopus 로고
    • Regulation of K-Cl cotransport: From function to genes
    • Adragna NC, Fulvio MD, Lauf PK: Regulation of K-Cl cotransport: From function to genes. J Membr Biol 2004;201:109-137.
    • (2004) J Membr Biol , vol.201 , pp. 109-137
    • Adragna, N.C.1    Fulvio, M.D.2    Lauf, P.K.3
  • 3
    • 33846941876 scopus 로고    scopus 로고
    • Cotransporters, WNKs and hypertension: Important leads from the study of monogenetic disorders of blood pressure regulation
    • Flatman PW: Cotransporters, WNKs and hypertension: Important leads from the study of monogenetic disorders of blood pressure regulation. ClinSci 2007;112:203-216.
    • (2007) ClinSci , vol.112 , pp. 203-216
    • Flatman, P.W.1
  • 4
    • 0035860734 scopus 로고    scopus 로고
    • Modulation of ion transport by direct targeting of protein phosphatase type 1 to the Na-K-Cl cotransporter
    • Darman RB, Flemmer A, Forbush B: Modulation of ion transport by direct targeting of protein phosphatase type 1 to the Na-K-Cl cotransporter. J BiolChem 2001;276:34359-34362.
    • (2001) J BiolChem , vol.276 , pp. 34359-34362
    • Darman, R.B.1    Flemmer, A.2    Forbush, B.3
  • 5
    • 0037020145 scopus 로고    scopus 로고
    • A regulatory locus of phosphorylation in the N terminus of the Na-K-Cl cotransporter, NKCC1
    • Darman RB, Forbush B: A regulatory locus of phosphorylation in the N terminus of the Na-K-Cl cotransporter, NKCC1. J BiolChem 2002;277:37542-37550.
    • (2002) J BiolChem , vol.277 , pp. 37542-37550
    • Darman, R.B.1    Forbush, B.2
  • 6
    • 0037020095 scopus 로고    scopus 로고
    • Activation of the Na-K-Cl cotransporter NKCC1 detected with a phospho-specific antibody
    • Flemmer AW, Gimenez I, Dowd BF, Darman RB, Forbush B: Activation of the Na-K-Cl cotransporter NKCC1 detected with a phospho-specific antibody. J Biol Chem 2002;277:37551-37558.
    • (2002) J Biol Chem , vol.277 , pp. 37551-37558
    • Flemmer, A.W.1    Gimenez, I.2    Dowd, B.F.3    Darman, R.B.4    Forbush, B.5
  • 7
    • 0026465685 scopus 로고
    • The Na-KClcotransport protein of shark rectal gland. II Regulation by direct phosphorylation
    • Lytle C, Forbush III B: The Na-KClcotransport protein of shark rectal gland. II Regulation by direct phosphorylation. J Biol Chem 1992;267:25438- 25443.
    • (1992) J Biol Chem , vol.267 , pp. 25438-25443
    • Lytle, C.1    Forbush III, B.2
  • 8
    • 0036838195 scopus 로고    scopus 로고
    • Coordinate modulation of Na-K-2Cl cotransport and K-Cl cotransport by cell volume and chloride
    • Lytle C, McManus T: Coordinate modulation of Na-K-2Cl cotransport and K-Cl cotransport by cell volume and chloride. Am J Physiol Cell Physiol 2002;283:C1422-C1431.
    • (2002) Am J Physiol Cell Physiol , vol.283
    • Lytle, C.1    McManus, T.2
  • 9
    • 0029881331 scopus 로고    scopus 로고
    • III: Regulatory phosphorylation of the secretory Na-KCl cotransporter: modulation by cytoplasmic Cl
    • Lytle C, Forbush B, III: Regulatory phosphorylation of the secretory Na-KCl cotransporter: modulation by cytoplasmic Cl. Am J Physiol 1996;270:C437-C448.
    • (1996) Am J Physiol , vol.270
    • Lytle, C.1    Forbush, B.2
  • 10
    • 0042847432 scopus 로고    scopus 로고
    • PASK (prolinealanine- rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1)
    • Dowd BF, Forbush B: PASK (prolinealanine- rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1). J Biol Chem 2003;278:27347-27353.
    • (2003) J Biol Chem , vol.278 , pp. 27347-27353
    • Dowd, B.F.1    Forbush, B.2
  • 14
    • 33749440293 scopus 로고    scopus 로고
    • WNK protein kinases modulate cellular Cl- flux by altering the phosphorylation state of the Na-K-Cl and K-Cl cotransporters
    • Kahle KT, Rinehart J, Ring A, Gimenez I, Gamba G, Hebert SC, Lifton RP: WNK protein kinases modulate cellular Cl- flux by altering the phosphorylation state of the Na-K-Cl and K-Cl cotransporters. Physiology 2006;21:326-335.
    • (2006) Physiology , vol.21 , pp. 326-335
    • Kahle, K.T.1    Rinehart, J.2    Ring, A.3    Gimenez, I.4    Gamba, G.5    Hebert, S.C.6    Lifton, R.P.7
  • 15
    • 30644472724 scopus 로고    scopus 로고
    • Characterization of SPAK and OSR1, regulatory kinases of the NA-K-2CL cotransporter
    • Gagnon KB, England R, Delpire E: Characterization of SPAK and OSR1, Regulatory Kinases of the Na-K-2Cl Cotransporter. Mol Cell Biol 2006;26:689-698.
    • (2006) Mol Cell Biol , vol.26 , pp. 689-698
    • Gagnon, K.B.1    England, R.2    Delpire, E.3
  • 16
    • 0037184942 scopus 로고    scopus 로고
    • Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-Alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)
    • Piechotta K, Lu J, Delpire E: Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-Alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1). J Biol Chem 2002;277:50812-50819.
    • (2002) J Biol Chem , vol.277 , pp. 50812-50819
    • Piechotta, K.1    Lu, J.2    Delpire, E.3
  • 17
    • 0346101747 scopus 로고    scopus 로고
    • Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase
    • Piechotta K, Garbarini N, England R, Delpire E: Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase. J Biol Chem 2003;278:52848-52856.
    • (2003) J Biol Chem , vol.278 , pp. 52848-52856
    • Piechotta, K.1    Garbarini, N.2    England, R.3    Delpire, E.4
  • 18
    • 33744820299 scopus 로고    scopus 로고
    • SPAK and OSR1, key kinases involved in the regulation of chloride transport
    • Delpire E, Gagnon KB: SPAK and OSR1, key kinases involved in the regulation of chloride transport. Acta Physiol 2006;187:103-113.
    • (2006) Acta Physiol , vol.187 , pp. 103-113
    • Delpire, E.1    Gagnon, K.B.2
  • 21
    • 26844532768 scopus 로고    scopus 로고
    • The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome, phosphorylate and active SPAK and OSR1 protein kinases
    • Vitari AC, Deak M, Morrice NA, Alessi DR: The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome, phosphorylate and active SPAK and OSR1 protein kinases. Biochem J 2005;391:17-24.
    • (2005) Biochem J , vol.391 , pp. 17-24
    • Vitari, A.C.1    Deak, M.2    Morrice, N.A.3    Alessi, D.R.4
  • 22
    • 30044442784 scopus 로고    scopus 로고
    • WNK1 Regulates Phosphorylation of Cation- Chloride-coupled Cotransporters via the STE20-related Kinases, SPAK and OSR1
    • Moriguchi T, Urushiyama S, Hisamoto N, Iemura S, Uchida S, Natsume T, Matsumoto K, Shibuya H: WNK1 Regulates Phosphorylation of Cation- Chloride-coupled Cotransporters via the STE20-related Kinases, SPAK and OSR1. J Biol Chem 2005;280:42685-42693.
    • (2005) J Biol Chem , vol.280 , pp. 42685-42693
    • Moriguchi, T.1    Urushiyama, S.2    Hisamoto, N.3    Iemura, S.4    Uchida, S.5    Natsume, T.6    Matsumoto, K.7    Shibuya, H.8
  • 23
    • 33745530924 scopus 로고    scopus 로고
    • Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1
    • Vitari AC, Thastrup J, Rafiqi FH, Deak M, Morrice NA, Karlsson HK, Alessi DR: Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1. Biochem J 2006;397:223-231.
    • (2006) Biochem J , vol.397 , pp. 223-231
    • Vitari, A.C.1    Thastrup, J.2    Rafiqi, F.H.3    Deak, M.4    Morrice, N.A.5    Karlsson, H.K.6    Alessi, D.R.7
  • 26
    • 0028201013 scopus 로고
    • Molecular cloning, primary structure and characterization of two members of the mammalian electroneutral sodium- (potassium)-chloride cotransporter family expressed in kidney
    • Gamba G, Miyanoshita A, Lombardi M, Lytton J, Lee WS, Hediger MA, Hebert SC: Molecular cloning, primary structure and characterization of two members of the mammalian electroneutral sodium- (potassium)-chloride cotransporter family expressed in kidney. J Biol Chem 1994;269:17713-17722.
    • (1994) J Biol Chem , vol.269 , pp. 17713-17722
    • Gamba, G.1    Miyanoshita, A.2    Lombardi, M.3    Lytton, J.4    Lee, W.S.5    Hediger, M.A.6    Hebert, S.C.7
  • 27
    • 0034730622 scopus 로고    scopus 로고
    • Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4
    • Mercado A, Song L, Vazquez N, Mount DB, Gamba G: Functional Comparison of the K+-Cl- Cotransporters KCC1 and KCC4. J Biol Chem 2000;275:30326-30334.
    • (2000) J Biol Chem , vol.275 , pp. 30326-30334
    • Mercado, A.1    Song, L.2    Vazquez, N.3    Mount, D.B.4    Gamba, G.5
  • 31
    • 56349151939 scopus 로고    scopus 로고
    • The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway
    • Richardson C, Alessi DR: The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway. J Cell Sci 2008;121:3293-3304.
    • (2008) J Cell Sci , vol.121 , pp. 3293-3304
    • Richardson, C.1    Alessi, D.R.2
  • 33
    • 38749087627 scopus 로고    scopus 로고
    • SPAK and OSR1: STE20 kinases involved in the regulation of ion homoeostasis and volume control in mammalian cells
    • Delpire E, Gagnon KB: SPAK and OSR1: STE20 kinases involved in the regulation of ion homoeostasis and volume control in mammalian cells. Biochem J 2008;409:321-331.
    • (2008) Biochem J , vol.409 , pp. 321-331
    • Delpire, E.1    Gagnon, K.B.2
  • 35
    • 34250785553 scopus 로고    scopus 로고
    • A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter
    • Gagnon KB, England R, Delpire E: A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter. Cell Physiol Biochem 2007;20:131-142.
    • (2007) Cell Physiol Biochem , vol.20 , pp. 131-142
    • Gagnon, K.B.1    England, R.2    Delpire, E.3
  • 37
    • 30644458584 scopus 로고    scopus 로고
    • Volume sensitivity of cation-Clcotransporters is modulated by the interaction of two kinases: Ste20-related proline-Alanine-rich kinase and WNK4
    • Gagnon KB, England R, Delpire E: Volume sensitivity of cation-Clcotransporters is modulated by the interaction of two kinases: Ste20-related proline-Alanine-rich kinase and WNK4. Am J Physiol Cell Physiol 2006;290:C134-C142.
    • (2006) Am J Physiol Cell Physiol , vol.290
    • Gagnon, K.B.1    England, R.2    Delpire, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.