New class of squalene-based releasable nanoassemblies of paclitaxel, podophyllotoxin, camptothecin and epothilone A

European Journal of Medicinal Chemistry

Volumn 85, Issue , 2014, Pages 179-190

  Borrelli, Stella ^a   Christodoulou, Michael S ^a   Ficarra, Ilaria ^a   Silvani, Alessandra ^a   Cappelletti, Graziella ^a   Cartelli, Daniele ^a   Damia, Giovanna ^b   Ricci, Francesca ^b   Zucchetti, Massimo ^b   Dosio, Franco ^c   Passarella, Daniele ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

Author keywords

Camptothecin; Epothilone A; Nanoassemblies; Paclitaxel; Podophyllotoxin; Squalene derivatives

Indexed keywords

1,1',2 TRIS NORSQUALENE ALCOHOL; 1,1',2 TRIS NORSQUALENE ALDEHYDE; 2 HYDROXY 3 BROMOSQUALENE; 2,3 OXIDOSQUALENE; CAMPTOTHECIN; EPOTHILONE A; PACLITAXEL; PODOPHYLLOTOXIN; SQUALENE DERIVATIVE; UNCLASSIFIED DRUG; CAMPTOTHECIN DERIVATIVE; NANOPARTICLE; PACLITAXEL DERIVATIVE; PODOPHYLLOTOXIN DERIVATIVE; ANTINEOPLASTIC AGENT; DRUG CARRIER; EPOTHILONE DERIVATIVE; NANOMATERIAL; SQUALENE;

ARTICLE; ATOMIC FORCE MICROSCOPY; BIOLOGICAL ACTIVITY; CONJUGATE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG STABILITY; DRUG SYNTHESIS; EVALUATION STUDY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; IONIC STRENGTH; MICROTUBULE; ZETA POTENTIAL; A549 CELL LINE; ANTINEOPLASTIC ACTIVITY; CYTOTOXICITY; DRUG FORMULATION; MCF 7 CELL LINE; PARTICLE SIZE; CHEMISTRY; DRUG EFFECTS; DRUG RELEASE; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CAMPTOTHECIN; CELL LINE, TUMOR; DRUG CARRIERS; DRUG LIBERATION; EPOTHILONES; HUMANS; MCF-7 CELLS; MICROTUBULES; NANOSTRUCTURES; PACLITAXEL; PODOPHYLLOTOXIN; SQUALENE;

EID: 84905197789     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.07.035     Document Type: Article

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