Conjugation of squalene to acyclovir improves the affinity for biomembrane models

International Journal of Pharmaceutics

Volumn 382, Issue 1-2, 2009, Pages 73-79

  Sarpietro, Maria Grazia ^a   Micieli, Dorotea ^a   Rocco, Flavio ^b   Ceruti, Maurizio ^b   Castelli, Francesco ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

Acyclovir; Biomembrane models; DMPC; DSC; Squalenoyl acyclovir (SQACV)

Indexed keywords

ACICLOVIR; LIPOSOME; SQUALENE;

ARTICLE; BINDING AFFINITY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; DRUG UPTAKE; MEMBRANE BINDING; MEMBRANE MODEL; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ACYCLOVIR; ANTIVIRAL AGENTS; BIOLOGICAL TRANSPORT; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; DIMYRISTOYLPHOSPHATIDYLCHOLINE; LIPID BILAYERS; LIPOSOMES; MODELS, BIOLOGICAL; PERMEABILITY; PRODRUGS; SQUALENE; TECHNOLOGY, PHARMACEUTICAL; TRANSITION TEMPERATURE;

EID: 70350210492     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.08.012     Document Type: Article

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