-
2
-
-
0041703019
-
-
A. J. ten Tije, J. Verweij, W. J. Loos, A. Sparreboom, Clin. Pharmacokinet. 2003, 42, 665.
-
(2003)
Clin. Pharmacokinet.
, vol.42
, pp. 665
-
-
ten Tije, A.J.1
Verweij, J.2
Loos, W.J.3
Sparreboom, A.4
-
3
-
-
0025326680
-
-
R. B. Weiss, R.C. Donehower, P. H. Wiernik, T Ohnuma, R. J. Gralla, D. L. Trump, J. R. Baker Jr, D. A. Van Echo, D. D. Von Hoff, B Leyland-Jones, J. Clin. Oncol. 1990, 8, 1263.
-
(1990)
J. Clin. Oncol.
, vol.8
, pp. 1263
-
-
Weiss, R.B.1
Donehower, R.C.2
Wiernik, P.H.3
Ohnuma, T.4
Gralla, R.J.5
Trump, D.L.6
Baker Jr, J.R.7
Van Echo, D.A.8
Von Hoff, D.D.9
Leyland-Jones, B.10
-
5
-
-
77952168147
-
-
F. Petrelli, K. Borgonovo, S. Barni, Expert Opin. Pharmacother. 2010, 11, 1413.
-
(2010)
Expert Opin. Pharmacother.
, vol.11
, pp. 1413
-
-
Petrelli, F.1
Borgonovo, K.2
Barni, S.3
-
6
-
-
0024597827
-
-
H. M. Deutsch, J. A. Glinski, M. Hernandez, R. D. Haugwitz, L. V. Narayanan, M. Suffness, L. H. Zalkow, J. Med. Chem. 1989, 32, 788.
-
(1989)
J. Med. Chem.
, vol.32
, pp. 788
-
-
Deutsch, H.M.1
Glinski, J.A.2
Hernandez, M.3
Haugwitz, R.D.4
Narayanan, L.V.5
Suffness, M.6
Zalkow, L.H.7
-
7
-
-
0027258227
-
-
K. C. Nicolaou, C. Riemer, M. A. Kerr, D. R. Rideout, W. W. Wrasidlo, Nature 1993, 364, 464.
-
(1993)
Nature
, vol.364
, pp. 464
-
-
Nicolaou, K.C.1
Riemer, C.2
Kerr, M.A.3
Rideout, D.R.4
Wrasidlo, W.W.5
-
9
-
-
0026567883
-
-
A. E. Mathew, M. R. Mejillano, J. P. Nath, R. H. Himes, V. J. Stella, J. Med. Chem. 1992, 35, 145.
-
(1992)
J. Med. Chem.
, vol.35
, pp. 145
-
-
Mathew, A.E.1
Mejillano, M.R.2
Nath, J.P.3
Himes, R.H.4
Stella, V.J.5
-
10
-
-
33644981818
-
-
A. Battaglia, A. Guerrini, E. Baldelli, G. Fontana, G. Varchi, C. Samori, E. Bombardelli, Tetrahedron Lett. 2006, 47, 2667.
-
(2006)
Tetrahedron Lett.
, vol.47
, pp. 2667
-
-
Battaglia, A.1
Guerrini, A.2
Baldelli, E.3
Fontana, G.4
Varchi, G.5
Samori, C.6
Bombardelli, E.7
-
11
-
-
0031081690
-
-
D. B. A. de Bont, R. G. G. Leenders, H. J. Haisma, I. van der Meulen-Muileman, H. W. Scheeren, Bioorg. Med. Chem. 1997, 5, 405.
-
(1997)
Bioorg. Med. Chem.
, vol.5
, pp. 405
-
-
de Bont, D.B.A.1
Leenders, R.G.G.2
Haisma, H.J.3
van der Meulen-Muileman, I.4
Scheeren, H.W.5
-
12
-
-
0032488645
-
-
T. Takahashi, H. Tsukamoto, H. Yamada, Bioorg. Med. Chem. Lett. 1998, 8, 113.
-
(1998)
Bioorg. Med. Chem. Lett.
, vol.8
, pp. 113
-
-
Takahashi, T.1
Tsukamoto, H.2
Yamada, H.3
-
13
-
-
0026317822
-
-
Z. Zhao, D. G. I. Kingston, A. R. Croswell, J. Nat. Prod. 1991, 54, 1607.
-
(1991)
J. Nat. Prod.
, vol.54
, pp. 1607
-
-
Zhao, Z.1
Kingston, D.G.I.2
Croswell, A.R.3
-
14
-
-
0031016893
-
-
W. C. Rose, J. L. Clark, F. Y. F. Lee, A. M. Casazza, Cancer Chemother. Pharmacol. 1997, 39, 486.
-
(1997)
Cancer Chemother. Pharmacol.
, vol.39
, pp. 486
-
-
Rose, W.C.1
Clark, J.L.2
Lee, F.Y.F.3
Casazza, A.M.4
-
15
-
-
0027290772
-
-
Y. Ueda, A. B. Mikkilineni, J. O. Knipe, W. C. Rose, A. M. Casazza, D. M. Vyas, Bioorg. Med. Chem. Lett. 1993, 3, 1761.
-
(1993)
Bioorg. Med. Chem. Lett.
, vol.3
, pp. 1761
-
-
Ueda, Y.1
Mikkilineni, A.B.2
Knipe, J.O.3
Rose, W.C.4
Casazza, A.M.5
Vyas, D.M.6
-
16
-
-
78649694252
-
-
J. S. Sohn, J. I. Jin, M. Hess, B. W. Jo, Polym. Chem. 2010, 1, 778.
-
(2010)
Polym. Chem.
, vol.1
, pp. 778
-
-
Sohn, J.S.1
Jin, J.I.2
Hess, M.3
Jo, B.W.4
-
17
-
-
35348833548
-
-
S. Papas, T. Akoumianaki, C. Kalogiros, L. Hadjiarapoglou, P. A. Theodoropoulos, V. Tsikaris, J. Pept. Sci. 2007, 13, 662.
-
(2007)
J. Pept. Sci.
, vol.13
, pp. 662
-
-
Papas, S.1
Akoumianaki, T.2
Kalogiros, C.3
Hadjiarapoglou, L.4
Theodoropoulos, P.A.5
Tsikaris, V.6
-
18
-
-
0344824453
-
-
T. A. Kirschberg, C. L. VanDeusen, J. B. Rothbard, M. Yang, P. A. Wender, Org. Lett. 2003, 5, 3459.
-
(2003)
Org. Lett.
, vol.5
, pp. 3459
-
-
Kirschberg, T.A.1
VanDeusen, C.L.2
Rothbard, J.B.3
Yang, M.4
Wender, P.A.5
-
19
-
-
0036242840
-
-
J. W. Lee, J. Y. Lu, P. S. Low, P. L. Fuchs, Bioorg. Med. Chem. 2002, 10, 2397.
-
(2002)
Bioorg. Med. Chem.
, vol.10
, pp. 2397
-
-
Lee, J.W.1
Lu, J.Y.2
Low, P.S.3
Fuchs, P.L.4
-
20
-
-
13944278751
-
-
X. Chen, C. Plasencia, Y. Hou, N. Neamati, J. Med. Chem. 2005, 48, 1098.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 1098
-
-
Chen, X.1
Plasencia, C.2
Hou, Y.3
Neamati, N.4
-
22
-
-
62549144354
-
-
K. Abu Ajaj, M. L. Biniossek, F. Kratz, Bioconjugate Chem. 2009, 20, 390.
-
(2009)
Bioconjugate Chem.
, vol.20
, pp. 390
-
-
Ajaj, K.A.1
Biniossek, M.L.2
Kratz, F.3
-
23
-
-
33645868648
-
-
S. Wang, N. Z. Zhelev, S. Duff, P. M. Fischer, Bioorg. Med. Chem. Lett. 2006, 16, 2628.
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 2628
-
-
Wang, S.1
Zhelev, N.Z.2
Duff, S.3
Fischer, P.M.4
-
24
-
-
13644257605
-
-
B. Thierry, P. Kujawa, C. Tkaczyk, F. M. Winnik, L. Bilodeau, M. Tabrizian, J. Am. Chem. Soc. 2005, 127, 1626.
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 1626
-
-
Thierry, B.1
Kujawa, P.2
Tkaczyk, C.3
Winnik, F.M.4
Bilodeau, L.5
Tabrizian, M.6
-
25
-
-
57349142938
-
-
Y. S. Lin, R. Tungpradit, S. Sinchaikul, F. M. An, D. Z. Liu, S. Phutrakul, S. T. Chen, J. Med. Chem. 2008, 51, 7428.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 7428
-
-
Lin, Y.S.1
Tungpradit, R.2
Sinchaikul, S.3
An, F.M.4
Liu, D.Z.5
Phutrakul, S.6
Chen, S.T.7
-
26
-
-
54549097056
-
-
E. Lee, J. Lee, I.-H. Lee, M. Yu, H. Kim, S. Y. Chae, S. Jon, J. Med. Chem. 2008, 51, 6442.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 6442
-
-
Lee, E.1
Lee, J.2
Lee, I.-H.3
Yu, M.4
Kim, H.5
Chae, S.Y.6
Jon, S.7
-
27
-
-
44949198237
-
-
S. M. Ansell, S. A. Johnstone, P. G. Tardi, L. Lo, S. Xie, Y. Shu, T. O Harasym, N. L. Harasym, L. Williams, D. Bermudes, B. D. Liboiron, W. Saad, R. K. Prud'homme, L. D. Mayer, J. Med. Chem. 2008, 51, 3288.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 3288
-
-
Ansell, S.M.1
Johnstone, S.A.2
Tardi, P.G.3
Lo, L.4
Xie, S.5
Shu, Y.6
Harasym, T.O.7
Harasym, N.L.8
Williams, L.9
Bermudes, D.10
Liboiron, B.D.11
Saad, W.12
Prud'homme, R.K.13
Mayer, L.D.14
-
28
-
-
78649634752
-
-
B. Elsadek, R. Graeser, N. Esser, C. Schäfer-Obodozie, K. A. Ajaj, C. Unger, A. Warnecke, T. Saleem, N. El-Megely, H. Madkor, F. Kratz, Eur. J. Cancer 2010, 46, 3434.
-
(2010)
Eur. J. Cancer
, vol.46
, pp. 3434
-
-
Elsadek, B.1
Graeser, R.2
Esser, N.3
Schäfer-Obodozie, C.4
Ajaj, K.A.5
Unger, C.6
Warnecke, A.7
Saleem, T.8
El-Megely, N.9
Madkor, H.10
Kratz, F.11
-
29
-
-
33746222883
-
-
M. Skwarczynski, M. Noguchi, S. Hirota, Y. Sohma, T. Kimura, Y. Hayashi, Y. Kiso, Bioorg. Med. Chem. Lett. 2006, 16, 4492.
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 4492
-
-
Skwarczynski, M.1
Noguchi, M.2
Hirota, S.3
Sohma, Y.4
Kimura, T.5
Hayashi, Y.6
Kiso, Y.7
-
31
-
-
84879608267
-
-
U.S. Patent 5, 534, 499.
-
S. Ansell, U.S. Patent 5, 1996, 534, 499.
-
(1996)
-
-
Ansell, S.1
-
32
-
-
17644366858
-
-
P. J. Stevens, M. Sekido, R. J. Lee, Pharm. Res. 2004, 21, 2153.
-
(2004)
Pharm. Res.
, vol.21
, pp. 2153
-
-
Stevens, P.J.1
Sekido, M.2
Lee, R.J.3
-
33
-
-
16744367603
-
-
W. R. Perkins, I. Ahmad, X. Li, D. J. Hirsh, G. R. Masters, C. J. Feko, J. K. Lee, S. Ali, J. Nguyen, J. Schupsky, C. Herbert, A. S. Janoff, E. Mayhew, Int. J. Pharm. 2000, 200, 27.
-
(2000)
Int. J. Pharm.
, vol.200
, pp. 27
-
-
Perkins, W.R.1
Ahmad, I.2
Li, X.3
Hirsh, D.J.4
Masters, G.R.5
Feko, C.J.6
Lee, J.K.7
Ali, S.8
Nguyen, J.9
Schupsky, J.10
Herbert, C.11
Janoff, A.S.12
Mayhew, E.13
-
34
-
-
0035097914
-
-
S. Ali, I. Ahmad, A. Peters, G. Masters, S. Minchey, A. Janoff, E. Mayhew, Anti-Cancer Drugs 2001, 12, 117.
-
(2001)
Anti-Cancer Drugs
, vol.12
, pp. 117
-
-
Ali, S.1
Ahmad, I.2
Peters, A.3
Masters, G.4
Minchey, S.5
Janoff, A.6
Mayhew, E.7
-
35
-
-
24744446010
-
-
T. Y. Zakharian, A. Seryshev, B. Sitharaman, B. E. Gilbert, V. Knight, L. J. Wilson, J. Am. Chem. Soc. 2005, 127, 12508.
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 12508
-
-
Zakharian, T.Y.1
Seryshev, A.2
Sitharaman, B.3
Gilbert, B.E.4
Knight, V.5
Wilson, L.J.6
-
36
-
-
0037426690
-
-
B. B. Lundberg, V. Risovic, M. Ramaswamy, K. M. Wasan, J. Control. Release 2003, 86, 93.
-
(2003)
J. Control. Release
, vol.86
, pp. 93
-
-
Lundberg, B.B.1
Risovic, V.2
Ramaswamy, M.3
Wasan, K.M.4
-
37
-
-
18744406323
-
-
D. G. Rodrigues, D. A. Maria, D. C. Fernandes, C. J. Valduga, R. D. Couto, O. C. M. Ibanez, R. C. Maranhao, Cancer Chemother. Pharmacol. 2005, 55, 565.
-
(2005)
Cancer Chemother. Pharmacol.
, vol.55
, pp. 565
-
-
Rodrigues, D.G.1
Maria, D.A.2
Fernandes, D.C.3
Valduga, C.J.4
Couto, R.D.5
Ibanez, O.C.M.6
Maranhao, R.C.7
-
38
-
-
77953081486
-
-
X.-Y. Ke, B.-J. Zhao, X. Zhao, Y. Wang, Y. Huang, X.-M. Chen, B.-X. Zhao, S.-S. Zhao, X. Zhang, Q. Zhang, Biomaterials 2010, 31, 5855.
-
(2010)
Biomaterials
, vol.31
, pp. 5855
-
-
Ke, X.-Y.1
Zhao, B.-J.2
Zhao, X.3
Wang, Y.4
Huang, Y.5
Chen, X.-M.6
Zhao, B.-X.7
Zhao, S.-S.8
Zhang, X.9
Zhang, Q.10
-
39
-
-
0034787765
-
-
M. O. Bradley, N. L. Webb, F. H. Anthony, P. Devanesan, P. A. Witman, S. Hemamalini, M. C. Chander, S. D. Baker, L. He, S. B. Horwits, C. S. Swindell, Clin. Cancer Res. 2001, 7, 3229.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 3229
-
-
Bradley, M.O.1
Webb, N.L.2
Anthony, F.H.3
Devanesan, P.4
Witman, P.A.5
Hemamalini, S.6
Chander, M.C.7
Baker, S.D.8
He, L.9
Horwits, S.B.10
Swindell, C.S.11
-
40
-
-
79953324540
-
-
A. Y. Bedikian, R. C. DeConti, R. Conry, S. Agarwala, N. Papadopoulos, K. B. Kim, M. Ernstoff, Ann. Oncol. 2011, 22, 787.
-
(2011)
Ann. Oncol.
, vol.22
, pp. 787
-
-
Bedikian, A.Y.1
DeConti, R.C.2
Conry, R.3
Agarwala, S.4
Papadopoulos, N.5
Kim, K.B.6
Ernstoff, M.7
-
41
-
-
33846178254
-
-
P. Couvreur, B. Stella, L. H. Reddy, H. Hillaireau, C. Dubernet, D. Desmaële, S. Lepêtre-Mouelhi, F. Rocco, N. Dereuddre-Bosquet, P. Clayette, V. Rosilio, V. Marsaud, J.-M. Renoir, L. Cattel, Nano Lett. 2006, 6, 2544.
-
(2006)
Nano Lett.
, vol.6
, pp. 2544
-
-
Couvreur, P.1
Stella, B.2
Reddy, L.H.3
Hillaireau, H.4
Dubernet, C.5
Desmaële, D.6
Lepêtre-Mouelhi, S.7
Rocco, F.8
Dereuddre-Bosquet, N.9
Clayette, P.10
Rosilio, V.11
Marsaud, V.12
Renoir, J.-M.13
Cattel, L.14
-
42
-
-
39449128320
-
-
P. Couvreur, L. H. Reddy, S. Mangenot, J. H. Poupaert, D. Desmaële, S. Lepêtre-Mouelhi, B. Pili C. Bourgaux, H. Amenitsch, M. Ollivon, SMALL 2008 4, 247.
-
(2008)
SMALL
, vol.4
, pp. 247
-
-
Couvreur, P.1
Reddy, L.H.2
Mangenot, S.3
Poupaert, J.H.4
Desmaële, D.5
Lepêtre-Mouelhi, S.6
Bourgaux, B.P.C.7
Amenitsch, H.8
Ollivon, M.9
-
43
-
-
79959415741
-
-
M. Raouane, D. Desmaele, M. Gilbert-Sirieix, C. Gueutin, F. Zouhiri, C. Bourgaux, E. Lepeltier, R. Gref, R. Ben Salah, G. Clayman, L. Massaad-Massade, P. Couvreur, J. Med. Chem. 2011, 54, 4067.
-
(2011)
J. Med. Chem.
, vol.54
, pp. 4067
-
-
Raouane, M.1
Desmaele, D.2
Gilbert-Sirieix, M.3
Gueutin, C.4
Zouhiri, F.5
Bourgaux, C.6
Lepeltier, E.7
Gref, R.8
Ben Salah, R.9
Clayman, G.10
Massaad-Massade, L.11
Couvreur, P.12
-
44
-
-
84862676788
-
-
D. Desmaële, R. Gref, P. Couvreur, J. Control. Release 2012, 161, 609.
-
(2012)
J. Control. Release
, vol.161
, pp. 609
-
-
Desmaële, D.1
Gref, R.2
Couvreur, P.3
-
45
-
-
77954871375
-
-
F. Dosio, L. H. Reddy, A. Ferrero, B. Stella, L. Cattel, P. Couvreur, Bioconjugate Chem. 2010, 21, 1349.
-
(2010)
Bioconjugate Chem.
, vol.21
, pp. 1349
-
-
Dosio, F.1
Reddy, L.H.2
Ferrero, A.3
Stella, B.4
Cattel, L.5
Couvreur, P.6
-
47
-
-
0036678094
-
-
T. P. Dinh, D. Carpenter, F. M. Leslie, T. F. Freund, I. Katona, S. L. Sensi, S. Kathuria, D. Piomelli, Proc. Natl. Acad. Sci. U.S.A. 2002, 99, 10819.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 10819
-
-
Dinh, T.P.1
Carpenter, D.2
Leslie, F.M.3
Freund, T.F.4
Katona, I.5
Sensi, S.L.6
Kathuria, S.7
Piomelli, D.8
-
49
-
-
0024597827
-
-
H. M. Deutsch, J. A. Glinski, M. Hernandez, R. D. Haugwitz, V. L. Narayanan, M. Suffness, L. H. Zalkow, J. Med. Chem. 1989, 32, 788.
-
(1989)
J. Med. Chem.
, vol.32
, pp. 788
-
-
Deutsch, H.M.1
Glinski, J.A.2
Hernandez, M.3
Haugwitz, R.D.4
Narayanan, V.L.5
Suffness, M.6
Zalkow, L.H.7
-
51
-
-
0023216282
-
-
M. Ceruti, G. Balliano, F. Viola, L. Cattel, N. Gerst, F. Schuber, Eur. J. Med. Chem. 1987, 22, 199.
-
(1987)
Eur. J. Med. Chem.
, vol.22
, pp. 199
-
-
Ceruti, M.1
Balliano, G.2
Viola, F.3
Cattel, L.4
Gerst, N.5
Schuber, F.6
-
52
-
-
0034725793
-
-
B. G. Jackson, S. W. Pedersen, J. W. Fisher, J. W. Misner, J. P. Gardner, M. A. Staszak, C. Doecke, J. Rizzo, J. Aikins, E. Farkas, K. L. Trinkle, J. Vicenzi, M. Reinhard, E. P. Kroeff, C. A. Higginbotham, R. J. Gazak, T. Y. Zhang, Tetrahedron 2000, 56, 5667.
-
(2000)
Tetrahedron
, vol.56
, pp. 5667
-
-
Jackson, B.G.1
Pedersen, S.W.2
Fisher, J.W.3
Misner, J.W.4
Gardner, J.P.5
Staszak, M.A.6
Doecke, C.7
Rizzo, J.8
Aikins, J.9
Farkas, E.10
Trinkle, K.L.11
Vicenzi, J.12
Reinhard, M.13
Kroeff, E.P.14
Higginbotham, C.A.15
Gazak, R.J.16
Zhang, T.Y.17
-
53
-
-
0030590418
-
-
P. H. Dussault, T. A. Anderson, M. R. Hayden, K. J. Koeller, Q. J. Niu, Tetrahedron 1996, 52, 12381.
-
(1996)
Tetrahedron
, vol.52
, pp. 12381
-
-
Dussault, P.H.1
Anderson, T.A.2
Hayden, M.R.3
Koeller, K.J.4
Niu, Q.J.5
-
55
-
-
0033519190
-
-
K. Gademann, M. Ernst, D. Hoyer, D. Seebach, Angew. Chem. Int. Ed. 1999, 38, 1223.
-
(1999)
Angew. Chem. Int. Ed.
, vol.38
, pp. 1223
-
-
Gademann, K.1
Ernst, M.2
Hoyer, D.3
Seebach, D.4
-
57
-
-
84879608355
-
-
D. Barbier, J.-P. Salvi, N. Walchshofer, J. Paris, Org. Prep. Proc. Intern. 1994, 26, 121.
-
(1994)
Org. Prep. Proc. Intern.
, vol.26
, pp. 121
-
-
Barbier, D.1
Salvi, J.-P.2
Walchshofer, N.3
Paris, J.4
-
58
-
-
0027050208
-
-
J. S. Yadav, I. Shekharam, D. Srinivas, Tetrahedron Lett. 1992, 33, 7973.
-
(1992)
Tetrahedron Lett.
, vol.33
, pp. 7973
-
-
Yadav, J.S.1
Shekharam, I.2
Srinivas, D.3
-
59
-
-
0020049344
-
-
G. Poste, C. Bucana, A. Raz, P. Bugelski, R. Kirsh, I. J. Fidler, Cancer Res. 1982, 42, 1412.
-
(1982)
Cancer Res.
, vol.42
, pp. 1412
-
-
Poste, G.1
Bucana, C.2
Raz, A.3
Bugelski, P.4
Kirsh, R.5
Fidler, I.J.6
-
60
-
-
84858428485
-
-
V. Allain, C. Bourgaux, P. Couvreur, Nucleic Acids Res. 2012, 40, 1891.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 1891
-
-
Allain, V.1
Bourgaux, C.2
Couvreur, P.3
-
61
-
-
77958103576
-
-
L. Bildstein, V. Marsaud, H. Chacun, S. Lepêtre-Mouelhi, D. Desmaële, P. Couvreur, C. Dubernet, Soft Matter. 2010, 6, 5570.
-
(2010)
Soft Matter.
, vol.6
, pp. 5570
-
-
Bildstein, L.1
Marsaud, V.2
Chacun, H.3
Lepêtre-Mouelhi, S.4
Desmaële, D.5
Couvreur, P.6
Dubernet, C.7
-
62
-
-
0028959193
-
-
R. L. Leibel, M. Rosenbaum, J. Hirsch, N. Engl. J. Med. 1995, 332, 621-8.
-
(1995)
N. Engl. J. Med.
, vol.332
, pp. 621-628
-
-
Leibel, R.L.1
Rosenbaum, M.2
Hirsch, J.3
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