Novel nanoassemblies composed of squalenoyl-paclitaxel derivatives: Synthesis, characterization, and biological evaluation

Bioconjugate Chemistry

Volumn 21, Issue 7, 2010, Pages 1349-1361

  Dosio, Franco ^b   Reddy, L Harivardhan ^a,c   Ferrero, Annalisa ^b   Stella, Barbara ^b   Cattel, Luigi ^b   Couvreur, Patrick ^c  

^a SANOFI   (France)

^b UNIVERSITY OF TURIN   (Italy)

^c UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMIC FORCE MICROSCOPY; CELL CULTURE; CONTROLLED DRUG DELIVERY; CYTOTOXICITY; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; HYDROPHILICITY; LIGHT SCATTERING; PARTICLE SIZE; POLYETHYLENE GLYCOLS; SOLUTIONS; SYNTHESIS (CHEMICAL); TARGETED DRUG DELIVERY;

ANTICANCER COMPOUNDS; BIO-CONJUGATION; BIOLOGICAL EVALUATION; DERIVATIVE SYNTHESIS; MODEL DRUGS; NANO-ASSEMBLIES; NATURAL LIPIDS; PACLITAXEL; PRODRUGS; SYNTHESIS EVALUATION;

ESTERS;

GLYCOLIC ACID DERIVATIVE; NANOPARTICLE; PACLITAXEL; PACLITAXEL DERIVATIVE; PRODRUG; SQUALENE; SQUALENE DERIVATIVE; SQUALENOYL PACLITAXEL; SQUALENOYL POLY(ETHYLENEGLYCOL)PACLITAXEL; SQUALENOYLDIGLOLYL PACLITAXEL; SQUALENOYLSUCCINYL PACLITAXEL; SUCCINIC ACID; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; ATOMIC FORCE MICROSCOPY; CELL STRAIN HT29; CELL STRAIN KB; CELL STRAIN KB31; CONJUGATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DRUG CYTOTOXICITY; DRUG RELEASE; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROPHILICITY; LIGHT SCATTERING; LUNG TUMOR; MICROTUBULE; NANOTECHNOLOGY; PARTICLE SIZE; SQUALENOYLATION; STRUCTURE ACTIVITY RELATION; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

EID: 77954871375     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc100154g     Document Type: Article

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