Deletion of periostin reduces muscular dystrophy and fibrosis in mice by modulating the transforming growth factor-β pathway

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 27, 2012, Pages 10978-10983

  Lorts, Angela ^a   Schwanekamp, Jennifer A ^a   Baudino, Troy A ^b   McNally, Elizabeth M ^c   Molkentin, Jeffery D ^a,d  

^a UNIVERSITY OF CINCINNATI   (United States)

^b TEXAS A M COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Collagen; Dystrophin glycoprotein complex; Paracrine; Transgenic mice

Indexed keywords

DELTA SARCOGLYCAN; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIAPHRAGM; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; GASTROCNEMIUS MUSCLE; GENE; GENE DELETION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MOUSE; MUSCLE FUNCTION; MUSCULAR DYSTROPHY; MYOFIBROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; QUADRICEPS FEMORIS MUSCLE; SIGNAL TRANSDUCTION; TISSUE REGENERATION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, NEUTRALIZING; CELL ADHESION MOLECULES; COLLAGEN; DISEASE MODELS, ANIMAL; FIBROSIS; MICE; MICE, KNOCKOUT; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, ANIMAL; PARACRINE COMMUNICATION; SARCOGLYCANS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

MUS; MUS MUSCULUS;

EID: 84863565398     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1204708109     Document Type: Article

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