Deficiency of biglycan causes cardiac fibroblasts to differentiate into a myofibroblast phenotype

Journal of Biological Chemistry

Volumn 286, Issue 19, 2011, Pages 17365-17375

  Melchior Becker, Ariane ^a   Dai, Guang ^a   Ding, Zhaoping ^b   Schäfer, Liliana ^c   Schrader, Jürgen ^b   Young, Marian F ^d   Fischer, Jens W ^a  

^a UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^d NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIAC FIBROBLASTS; CELL TYPES; COLLAGEN GELS; EXTRACELLULAR MATRICES; FOCAL ADHESIONS; IN-VITRO; IN-VIVO; MYOCARDIAL INFARCTION; MYOFIBROBLASTS; NEUTRALIZING ANTIBODIES; PHENOTYPIC CHARACTERIZATION; PROTEOGLYCANS; SCAR TISSUES; SMOOTH MUSCLE ACTINS; STRESS FIBERS; WILD TYPES;

AMINO ACIDS; CELL CULTURE; FIBROBLASTS; HEART; PHOSPHORYLATION; PROTEINS;

TISSUE;

ALPHA SMOOTH MUSCLE ACTIN; BIGLYCAN; COLLAGEN GEL; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME RECONSTITUTION; FOCAL ADHESION; HEART INFARCTION; HEART MUSCLE CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; MYOFIBROBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; STRESS FIBER; WILD TYPE;

ACTINS; ANIMALS; BIGLYCAN; CELL DIFFERENTIATION; EXTRACELLULAR MATRIX; FIBROBLASTS; MALE; MICE; MICE, TRANSGENIC; MUSCLE, SMOOTH; MYOCARDIUM; MYOFIBROBLASTS; PHENOTYPE; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

MUS;

EID: 79955775556     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.192682     Document Type: Article

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