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Volumn 18, Issue 48, 2014, Pages 1-159

Folate augmentation of treatment - Evaluation for depression (folated): Randomised trial and economic evaluation

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; FOLIC ACID; HOMOCYSTEINE; PLACEBO;

EID: 84905017800     PISSN: 13665278     EISSN: 20464924     Source Type: Journal    
DOI: 10.3310/hta18480     Document Type: Article
Times cited : (49)

References (187)
  • 1
    • 67449119906 scopus 로고    scopus 로고
    • World Health Organization and World Organization of Family Doctors, Geneva, Switzerland: WHO
    • World Health Organization and World Organization of Family Doctors. Integrating Mental Health into Primary Care: A Global Perspective. Geneva, Switzerland: WHO; 2008.
    • (2008) Integrating Mental Health Into Primary Care: A Global Perspective
  • 2
    • 9144229755 scopus 로고    scopus 로고
    • World Health Organization, Switzerland: WHO
    • World Health Organization. Investing in Mental Health. Geneva, Switzerland: WHO; 2003.
    • (2003) Investing In Mental Health. Geneva
  • 3
    • 84905017443 scopus 로고    scopus 로고
    • Beaumont J, editor, London: Office for National Statistics
    • Sweet D. In Beaumont J, editor. Health Clinical Research Centre. London: Office for National Statistics; 2011.
    • (2011) Health Clinical Research Centre
    • Sweet, D.1
  • 4
    • 78649387254 scopus 로고    scopus 로고
    • World Health Organization, Geneva, Switzerland: WHO, accessed March 2013
    • World Health Organization. Depression. Geneva, Switzerland: WHO; 2011. URL: www.who.int/topics/depression/en/(accessed March 2013).
    • (2011) Depression
  • 5
    • 80052376956 scopus 로고    scopus 로고
    • The size and burden of mental disorders and other disorders of the brain in Europe 2010
    • Wittchen HU, Jacobi F, Rehm J, Gustavsson A, Svensson M, Jonsson B, et al. The size and burden of mental disorders and other disorders of the brain in Europe 2010. Eur Neuropsychopharmacol 2011;21:655-79. http://dx.doi.org/10.1016/j.euroneuro.2011.07.018
    • (2011) Eur Neuropsychopharmacol , vol.21 , pp. 655-679
    • Wittchen, H.U.1    Jacobi, F.2    Rehm, J.3    Gustavsson, A.4    Svensson, M.5    Jonsson, B.6
  • 8
    • 1642389164 scopus 로고    scopus 로고
    • Prevalence and incidence studies of mood disorders: A systematic review of the literature
    • Waraich P, Goldner EM, Somers JM, Hsu L. Prevalence and incidence studies of mood disorders: a systematic review of the literature. Can J Psychiatry 2004;49:124-38.
    • (2004) Can J Psychiatry , vol.49 , pp. 124-138
    • Waraich, P.1    Goldner, E.M.2    Somers, J.M.3    Hsu, L.4
  • 9
    • 70350051602 scopus 로고    scopus 로고
    • National Collaborating Centre for Mental Health, London: British Psychological Society and Royal College of Psychiatrists
    • National Collaborating Centre for Mental Health. Depression: The NICE Guidance on the Treatment and Management of Depression in Adults. London: British Psychological Society and Royal College of Psychiatrists; 2010.
    • (2010) Depression: The NICE Guidance On the Treatment and Management of Depression In Adults
  • 10
    • 0031822289 scopus 로고    scopus 로고
    • The relationship of depression to cardiovascular disease: Epidemiology, biology, and treatment
    • Musselman DL, Evans DL, Nemeroff CB. The relationship of depression to cardiovascular disease: epidemiology, biology, and treatment. Arch Gen Psychiatry 1998;55:580-92. http://dx.doi.org/10.1001/archpsyc.55.7.580
    • (1998) Arch Gen Psychiatry , vol.55 , pp. 580-592
    • Musselman, D.L.1    Evans, D.L.2    Nemeroff, C.B.3
  • 12
    • 0346622392 scopus 로고    scopus 로고
    • Cost of depression among adults in England in 2000
    • Thomas CM, Morris S. Cost of depression among adults in England in 2000. Br J Psychiatry 2003;183:514-19. http://dx.doi.org/10.1192/bjp.183.6.514
    • (2003) Br J Psychiatry , vol.183 , pp. 514-519
    • Thomas, C.M.1    Morris, S.2
  • 13
    • 29444439213 scopus 로고    scopus 로고
    • The impact of residual symptoms on outcome of major depression
    • Kennedy N, Foy K. The impact of residual symptoms on outcome of major depression. Curr Psychiatry Rep 2005;7:441-6. http://dx.doi.org/10.1007/s11920-005-0065-9
    • (2005) Curr Psychiatry Rep , vol.7 , pp. 441-446
    • Kennedy, N.1    Foy, K.2
  • 14
    • 0028233413 scopus 로고
    • The time course of nonchronic major depressive disorder: Uniformity across episodes and samples
    • Coryell W, Akiskal HS, Leon AC, Winokur G, Maser JD, Mueller TI, et al. The time course of nonchronic major depressive disorder: uniformity across episodes and samples. Arch Gen Psychiatry 1994;51:405-10. http://dx.doi.org/10.1001/archpsyc.1994.03950050065007
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 405-410
    • Coryell, W.1    Akiskal, H.S.2    Leon, A.C.3    Winokur, G.4    Maser, J.D.5    Mueller, T.I.6
  • 15
    • 0034807318 scopus 로고    scopus 로고
    • Untreated short-term course of major depression: Meta-analysis of outcomes from studies using wait-list control groups
    • Posternak MA, Miller I. Untreated short-term course of major depression: meta-analysis of outcomes from studies using wait-list control groups. J Affect Disord 2001;66:139-46. http://dx.doi.org/10.1016/S0165-0327(00)00304-9
    • (2001) J Affect Disord , vol.66 , pp. 139-146
    • Posternak, M.A.1    Miller, I.2
  • 16
    • 84944368049 scopus 로고
    • Long-term outcome of episodes of major depression: Clinical and public health significance
    • Keller MB, Klerman GL, Lavori PW, Coryell W, Endicott J, Taylor J. Long-term outcome of episodes of major depression: clinical and public health significance. JAMA 1984;252:788-92. http://dx.doi.org/10.1001/jama.1984.03350060032024
    • (1984) JAMA , vol.252 , pp. 788-792
    • Keller, M.B.1    Klerman, G.L.2    Lavori, P.W.3    Coryell, W.4    Endicott, J.5    Taylor, J.6
  • 17
    • 0031926899 scopus 로고    scopus 로고
    • A prospective 12-year study of subsyndromal and syndromal depressive symptoms in unipolar major depressive disorders
    • Judd LL, Akiskal HS, Maser JD, Zeller PJ, Endicott J, Coryell W, et al. A prospective 12-year study of subsyndromal and syndromal depressive symptoms in unipolar major depressive disorders. Arch Gen Psychiatry 1998;55:694-700. http://dx.doi.org/10.1001/archpsyc.55.8.694
    • (1998) Arch Gen Psychiatry , vol.55 , pp. 694-700
    • Judd, L.L.1    Akiskal, H.S.2    Maser, J.D.3    Zeller, P.J.4    Endicott, J.5    Coryell, W.6
  • 18
    • 45349107889 scopus 로고    scopus 로고
    • Evidence-based guidelines for treating depressive disorders with antidepressants: Revision of the 2000 British Association for Psychopharmacology guidelines
    • Anderson IM, Ferrier IN, Baldwin RC, Cowen PJ, Howard L, Lewis G, et al. Evidence-based guidelines for treating depressive disorders with antidepressants: revision of the 2000 British Association for Psychopharmacology guidelines. J Psychopharmacol 2008;22:343-96. http://dx.doi.org/10.1177/0269881107088441
    • (2008) J Psychopharmacol , vol.22 , pp. 343-396
    • Anderson, I.M.1    Ferrier, I.N.2    Baldwin, R.C.3    Cowen, P.J.4    Howard, L.5    Lewis, G.6
  • 19
    • 0034566074 scopus 로고    scopus 로고
    • Antidepressant use patterns in clinical practices: Comparisons among tricyclic antidepressants and selective serotonin reuptake inhibitors
    • Donoghue J. Antidepressant use patterns in clinical practices: comparisons among tricyclic antidepressants and selective serotonin reuptake inhibitors. Acta Psychiatr Scand 2000;101:57-61. http://dx.doi.org/10.1111/j.1600-0447.2000.tb10949.x
    • (2000) Acta Psychiatr Scand , vol.101 , pp. 57-61
    • Donoghue, J.1
  • 21
    • 0037051872 scopus 로고    scopus 로고
    • Placebo response in studies of major depression: Variable, substantial, and growing
    • Walsh BT, Seidman SN, Sysko R, Gould M. Placebo response in studies of major depression: variable, substantial, and growing. JAMA 2002;287:1840-7. http://dx.doi.org/10.1001/jama.287.14.1840
    • (2002) JAMA , vol.287 , pp. 1840-1847
    • Walsh, B.T.1    Seidman, S.N.2    Sysko, R.3    Gould, M.4
  • 22
    • 33751338530 scopus 로고    scopus 로고
    • Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: STAR*D report
    • Rush AJ, Trivedi MH, Wisniewski SR, Nierenberg AA, Stewart JW, Warden D, et al. Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: STAR*D report. Am J Psychiatry 2006;163:1905-17. http://dx.doi.org/10.1176/appi.ajp.163.11.1905
    • (2006) Am J Psychiatry , vol.163 , pp. 1905-1917
    • Rush, A.J.1    Trivedi, M.H.2    Wisniewski, S.R.3    Nierenberg, A.A.4    Stewart, J.W.5    Warden, D.6
  • 23
    • 0036012842 scopus 로고    scopus 로고
    • Understanding crossnational differences in depression prevalence
    • Simon GE, Goldberg DP, von Korff M, Ustun TB. Understanding crossnational differences in depression prevalence. Psycholog Med 2002;32:585-94.
    • (2002) Psycholog Med , vol.32 , pp. 585-594
    • Simon, G.E.1    Goldberg, D.P.2    von Korff, M.3    Ustun, T.B.4
  • 24
    • 0037831023 scopus 로고    scopus 로고
    • The epidemiology of major depressive disorder: Results from the National Comorbidity Survey Replication (NCS-R)
    • Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR, et al. The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA 2003;289:3095-105. http://dx.doi.org/10.1001/jama.289.23.3095
    • (2003) JAMA , vol.289 , pp. 3095-3105
    • Kessler, R.C.1    Berglund, P.2    Demler, O.3    Jin, R.4    Koretz, D.5    Merikangas, K.R.6
  • 25
    • 0025865067 scopus 로고
    • Long-term treatment of depression
    • Kupfer DJ. Long-term treatment of depression. J Clin Psychiatry 1991;52(Suppl.):28-34.
    • (1991) J Clin Psychiatry , vol.52 , Issue.SUPPL. , pp. 28-34
    • Kupfer, D.J.1
  • 27
    • 77955480491 scopus 로고    scopus 로고
    • Half-baked? B vitamins and depression (editorial)
    • Roberts SH, Bedson E, Tranter R. Half-baked? B vitamins and depression (editorial). Am J Clin Nutr 2010;92:269-70.
    • (2010) Am J Clin Nutr , vol.92 , pp. 269-270
    • Roberts, S.H.1    Bedson, E.2    Tranter, R.3
  • 28
    • 56749098446 scopus 로고    scopus 로고
    • The folate puzzle: IV - folate and depression
    • Pauwels EKJ. The folate puzzle: IV - folate and depression. Drugs Future 2008;33:591-5. http://dx.doi.org/10.1358/dof.2008.033.07.1236397
    • (2008) Drugs Future , vol.33 , pp. 591-595
    • Pauwels, E.K.J.1
  • 29
    • 65649090902 scopus 로고    scopus 로고
    • Major depressive disorder and nutritional medicine: Review of monotherapies and adjuvant treatments
    • Sarris J, Schoendorfer N, Kavanagh DJ. Major depressive disorder and nutritional medicine: review of monotherapies and adjuvant treatments. Nutr Rev 2009;67:125-31. http://dx.doi.org/10.1111/j.1753-4887.2009.00180.x
    • (2009) Nutr Rev , vol.67 , pp. 125-131
    • Sarris, J.1    Schoendorfer, N.2    Kavanagh, D.J.3
  • 30
    • 75449091586 scopus 로고    scopus 로고
    • Vitamins, monoamines, and depression
    • Robinson DS. Vitamins, monoamines, and depression. Prim Psychiatry 2009;16:19-21.
    • (2009) Prim Psychiatry , vol.16 , pp. 19-21
    • Robinson, D.S.1
  • 31
    • 84905059783 scopus 로고    scopus 로고
    • Office of Dietary Supplements, Bethesda, MD: National Institutes of Health, accessed March 2013
    • Office of Dietary Supplements. Folate: Dietary Supplement Fact Sheet. Bethesda, MD: National Institutes of Health; 2009. URL: www.ods.od.nih.gov/factsheet/folate (accessed March 2013).
    • (2009) Folate: Dietary Supplement Fact Sheet
  • 33
    • 53049090216 scopus 로고    scopus 로고
    • Association of folate intake with the occurrence of depressive episodes in middle-aged French men and women
    • Astorg P, Couthouis A, De Courcy GP, Bertrais S, Arnault N, Meneton P, et al. Association of folate intake with the occurrence of depressive episodes in middle-aged French men and women. Br J Nutr 2008;100:183-7. http://dx.doi.org/10.1017/S0007114507873612
    • (2008) Br J Nutr , vol.100 , pp. 183-187
    • Astorg, P.1    Couthouis, A.2    de Courcy, G.P.3    Bertrais, S.4    Arnault, N.5    Meneton, P.6
  • 37
    • 0014191127 scopus 로고
    • Serum folate values in 423 psychiatric patients
    • Carney MWP. Serum folate values in 423 psychiatric patients. BMJ 1967;4:512-16. http://dx.doi.org/10.1136/bmj.4.5578.512
    • (1967) BMJ , vol.4 , pp. 512-516
    • Carney, M.W.P.1
  • 38
    • 65449118785 scopus 로고    scopus 로고
    • Folate, vitamin B12, homocysteine, and depressive symptoms in a population sample of older Chinese adults
    • Ng T, Feng L, Niti M, Kua E, Yap K. Folate, vitamin B12, homocysteine, and depressive symptoms in a population sample of older Chinese adults. J Am Geriatr Soc 2009;57:871-6. http://dx.doi.org/10.1111/j.1532-5415.2009.02229.x
    • (2009) J Am Geriatr Soc , vol.57 , pp. 871-876
    • Ng, T.1    Feng, L.2    Niti, M.3    Kua, E.4    Yap, K.5
  • 39
    • 0024370135 scopus 로고
    • Serum and red blood cell folate in depression
    • Abou-Saleh MT, Coppen A. Serum and red blood cell folate in depression. Acta Psychiatr Scand 1989;80:78-82. http://dx.doi.org/10.1111/j.1600-0447.1989.tb01303.x
    • (1989) Acta Psychiatr Scand , vol.80 , pp. 78-82
    • Abou-Saleh, M.T.1    Coppen, A.2
  • 40
    • 0034235205 scopus 로고    scopus 로고
    • Nutrition and depression: Focus on folate
    • Alpert JE, Mischoulon D, Nierenberg AA, Fava M. Nutrition and depression: focus on folate. Nutrition 2000;16:544-6. http://dx.doi.org/10.1016/S0899-9007(00)00327-0
    • (2000) Nutrition , vol.16 , pp. 544-546
    • Alpert, J.E.1    Mischoulon, D.2    Nierenberg, A.A.3    Fava, M.4
  • 42
    • 12444279964 scopus 로고    scopus 로고
    • Treatment of depression: Time to consider folic acid and vitamin B12
    • Coppen A, Bolander-Gouaille C. Treatment of depression: time to consider folic acid and vitamin B12. J Psychopharmacol 2005;19:59-65. http://dx.doi.org/10.1177/0269881105048899
    • (2005) J Psychopharmacol , vol.19 , pp. 59-65
    • Coppen, A.1    Bolander-Gouaille, C.2
  • 43
    • 43749101147 scopus 로고    scopus 로고
    • Predictive value of folate, vitamin B12 and homocysteine levels in late-life depression
    • Kim J-M, Stewart R, Kim S-W, Yang S-J, Shin I-S, Yoon J-S. Predictive value of folate, vitamin B12 and homocysteine levels in late-life depression. Br J Psychiatry 2008;192:268-74. http://dx.doi.org/10.1192/bjp.bp.107.039511
    • (2008) Br J Psychiatry , vol.192 , pp. 268-274
    • Kim, J.-M.1    Stewart, R.2    Kim, S.-W.3    Yang, S.-J.4    Shin, I.-S.5    Yoon, J.-S.6
  • 44
    • 77955482603 scopus 로고    scopus 로고
    • Longitudinal association of vitamin B-6, folate, and vitamin B-12 with depressive symptoms among older adults over time
    • Skarupski KA, Tangney C, Li H, Ouyang B, Evans DA, Morris MC. Longitudinal association of vitamin B-6, folate, and vitamin B-12 with depressive symptoms among older adults over time. Am J Clin Nutr 2010;92:330-5. http://dx.doi.org/10.3945/ajcn.2010.29413
    • (2010) Am J Clin Nutr , vol.92 , pp. 330-335
    • Skarupski, K.A.1    Tangney, C.2    Li, H.3    Ouyang, B.4    Evans, D.A.5    Morris, M.C.6
  • 45
    • 34347267644 scopus 로고    scopus 로고
    • Is low folate a risk factor for depression? A meta-analysis and exploration of heterogeneity
    • Gilbody S, Lightfoot T, Sheldon T. Is low folate a risk factor for depression? A meta-analysis and exploration of heterogeneity. J Epidemiol Community Health 2007;61:631-7. http://dx.doi.org/10.1136/jech.2006.050385
    • (2007) J Epidemiol Community Health , vol.61 , pp. 631-637
    • Gilbody, S.1    Lightfoot, T.2    Sheldon, T.3
  • 46
    • 54349102812 scopus 로고    scopus 로고
    • A longitudinal study of blood folate levels and depressive symptoms among young women in the Southampton Women's Survey
    • Kendrick T, Dunn N, Robinson S, Oestmann A, Godfrey K, Cooper C, et al. A longitudinal study of blood folate levels and depressive symptoms among young women in the Southampton Women's Survey. J Epidemiol Community Health 2008;62:966-72. http://dx.doi.org/10.1136/jech.2007.069765
    • (2008) J Epidemiol Community Health , vol.62 , pp. 966-972
    • Kendrick, T.1    Dunn, N.2    Robinson, S.3    Oestmann, A.4    Godfrey, K.5    Cooper, C.6
  • 47
    • 77949613693 scopus 로고    scopus 로고
    • Natural food folate and late-life depression
    • Payne M, Jamerson BD, Potocky CF, et al. Natural food folate and late-life depression. J Nutr Elder 2009;28:348-58. http://dx.doi.org/10.1080/01639360903417181
    • (2009) J Nutr Elder , vol.28 , pp. 348-358
    • Payne, M.1    Jamerson, B.D.2    Potocky, C.F.3
  • 48
    • 77954600956 scopus 로고    scopus 로고
    • Mental health literacy, folic acid and vitamin B12, and physical activity for the prevention of depression in older adults: Randomised controlled trial
    • Walker JG, Mackinnon AJ, Batterham P, Jorm AF, Hickie I, McCarthy A, et al. Mental health literacy, folic acid and vitamin B12, and physical activity for the prevention of depression in older adults: randomised controlled trial. Br J Psychiatry 2010;197:45-54. http://dx.doi.org/10.1192/bjp.bp.109.075291
    • (2010) Br J Psychiatry , vol.197 , pp. 45-54
    • Walker, J.G.1    Mackinnon, A.J.2    Batterham, P.3    Jorm, A.F.4    Hickie, I.5    McCarthy, A.6
  • 49
    • 49649118607 scopus 로고    scopus 로고
    • Vitamins B12, B6, and folic acid for onset of depressive symptoms in older men: Results from a 2-year placebo-controlled randomized trial
    • Ford AH, Flicker L, Thomas J, Norman P, Jamrozik K, Almeida OP. Vitamins B12, B6, and folic acid for onset of depressive symptoms in older men: results from a 2-year placebo-controlled randomized trial. J Clin Psychiatry 2008;69:1203-9. http://dx.doi.org/10.4088/JCP.v69n0801
    • (2008) J Clin Psychiatry , vol.69 , pp. 1203-1209
    • Ford, A.H.1    Flicker, L.2    Thomas, J.3    Norman, P.4    Jamrozik, K.5    Almeida, O.P.6
  • 51
    • 25644439809 scopus 로고    scopus 로고
    • Homocysteine and folate metabolism in depression
    • Bottiglieri T. Homocysteine and folate metabolism in depression. Prog Neuropsychopharmacol Biol Psychiatry 2005;29:1103-12. http://dx.doi.org/10.1016/j.pnpbp.2005.06.021
    • (2005) Prog Neuropsychopharmacol Biol Psychiatry , vol.29 , pp. 1103-1112
    • Bottiglieri, T.1
  • 53
    • 17344366819 scopus 로고    scopus 로고
    • Relationship of homocysteine, folic acid and vitamin B12 with depression in a middle-aged community sample
    • Sachdev PS, Parslow RA, Lux O, Salonikas C, Wen W, Naidoo D, et al. Relationship of homocysteine, folic acid and vitamin B12 with depression in a middle-aged community sample. Psycholog Med 2005;35:529-38. http://dx.doi.org/10.1017/S0033291704003721
    • (2005) Psycholog Med , vol.35 , pp. 529-538
    • Sachdev, P.S.1    Parslow, R.A.2    Lux, O.3    Salonikas, C.4    Wen, W.5    Naidoo, D.6
  • 54
    • 16544380761 scopus 로고    scopus 로고
    • Association between depressive symptoms and serum concentrations of homocysteine in men: Population study
    • Tolmunen T, Hintikka J, Voutilainen S, Ruusunen A, Alfthan G, Nyyssonen K, et al. Association between depressive symptoms and serum concentrations of homocysteine in men: population study. Am J Clin Nutr 2004;80:1574-8.
    • (2004) Am J Clin Nutr , vol.80 , pp. 1574-1578
    • Tolmunen, T.1    Hintikka, J.2    Voutilainen, S.3    Ruusunen, A.4    Alfthan, G.5    Nyyssonen, K.6
  • 56
    • 0019416248 scopus 로고
    • Pathogenesis of subacute combined degeneration: Result of methyl group deficiency
    • Scott J, Dinn J, Wilson P, Weir D. Pathogenesis of subacute combined degeneration: result of methyl group deficiency. Lancet 1981;2:334-7. http://dx.doi.org/10.1016/S0140-6736(81)90649-8
    • (1981) Lancet , vol.2 , pp. 334-337
    • Scott, J.1    Dinn, J.2    Wilson, P.3    Weir, D.4
  • 57
    • 38049152741 scopus 로고    scopus 로고
    • In vitamin B12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations
    • Selhub J, Morris MS, Jacques PF. In vitamin B12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations. Proc Natl Acad Sci U S A 2007;104:1995-2000. http://dx.doi.org/10.1073/pnas.0709487104
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 1995-2000
    • Selhub, J.1    Morris, M.S.2    Jacques, P.F.3
  • 58
    • 40349097951 scopus 로고    scopus 로고
    • In vitamin B12 deficiency, higher serum folate is associated with increased homocysteine and methylmalonic acid concentrations
    • Quinlivan EP. In vitamin B12 deficiency, higher serum folate is associated with increased homocysteine and methylmalonic acid concentrations. Proc Natl Acad Sci U S A 2008;105:1387-8. http://dx.doi.org/10.1073/pnas.0711541105
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 1387-1388
    • Quinlivan, E.P.1
  • 59
    • 0018757898 scopus 로고
    • Folate deficiency and decreased brain 5-hydroxytryptamine synthesis in man and rat
    • Botez MI, Young SN, Bachevalier J, Gauthier S. Folate deficiency and decreased brain 5-hydroxytryptamine synthesis in man and rat. Nature 1979;278:182-3. http://dx.doi.org/10.1038/278182a0
    • (1979) Nature , vol.278 , pp. 182-183
    • Botez, M.I.1    Young, S.N.2    Bachevalier, J.3    Gauthier, S.4
  • 60
    • 77954457648 scopus 로고    scopus 로고
    • The role of folic acid in prevention and treatment of depression: An overview of existing evidence and implications for practice
    • Lazarou C, Kapsou M. The role of folic acid in prevention and treatment of depression: an overview of existing evidence and implications for practice. Complement Ther Clin Pract 2010;16:161-6. http://dx.doi.org/10.1016/j.ctcp.2010.01.003
    • (2010) Complement Ther Clin Pract , vol.16 , pp. 161-166
    • Lazarou, C.1    Kapsou, M.2
  • 61
    • 17044451981 scopus 로고    scopus 로고
    • Are the newer antidepressant drugs as effective as established physical treatments? Results from an Australasian clinical panel review
    • Parker G, Mitchell P, Wilhelm K, Menkes DB, Snowdon J, Schweitzer I, et al. Are the newer antidepressant drugs as effective as established physical treatments? Results from an Australasian clinical panel review. Aus N Z J Psychiatry 1999;33:874-81. http://dx.doi.org/10.1046/j.1440-1614.1999.00648.x
    • (1999) Aus N Z J Psychiatry , vol.33 , pp. 874-881
    • Parker, G.1    Mitchell, P.2    Wilhelm, K.3    Menkes, D.B.4    Snowdon, J.5    Schweitzer, I.6
  • 63
    • 0038045763 scopus 로고    scopus 로고
    • Prediction of treatment response in geriatric depression from baseline folate level: Interaction with SSRI or tricyclic antidepressant
    • Alpert M, Silva RR, Pouget ER. Prediction of treatment response in geriatric depression from baseline folate level: interaction with SSRI or tricyclic antidepressant. J Clin Psychopharmacol 2003;23:309-13. http://dx.doi.org/10.1097/01.jcp.0000084024.22282.cd
    • (2003) J Clin Psychopharmacol , vol.23 , pp. 309-313
    • Alpert, M.1    Silva, R.R.2    Pouget, E.R.3
  • 64
    • 3242663365 scopus 로고    scopus 로고
    • Folate for depressive disorders: Systematic review and meta-analysis of randomised controlled trials
    • Taylor MJ, Carney SM, Goodwin GM, Geddes JR. Folate for depressive disorders: systematic review and meta-analysis of randomised controlled trials. J Psychopharmacol 2004;18:251-6.
    • (2004) J Psychopharmacol , vol.18 , pp. 251-256
    • Taylor, M.J.1    Carney, S.M.2    Goodwin, G.M.3    Geddes, J.R.4
  • 65
    • 0033858407 scopus 로고    scopus 로고
    • Enhancement of the antidepressant action of fluoxetine by folic acid: Randomised, placebo controlled trial
    • Coppen A, Bailey J. Enhancement of the antidepressant action of fluoxetine by folic acid: randomised, placebo controlled trial. J Affect Disord 2000;60:121-30. http://dx.doi.org/10.1016/S0165-0327(00)00153-1
    • (2000) J Affect Disord , vol.60 , pp. 121-130
    • Coppen, A.1    Bailey, J.2
  • 67
    • 67649649623 scopus 로고    scopus 로고
    • Adjuvant folate with escitalopram treatment and homocysteine, folate, vitamin B-12 levels in patients with major depressive disorder
    • Basoglu C, Ates M, Algul A, Ipcioglu OM, Gecici O, Yilmaz O, et al. Adjuvant folate with escitalopram treatment and homocysteine, folate, vitamin B-12 levels in patients with major depressive disorder. Bull Clin Psychopharmacol 2009;19:135-42.
    • (2009) Bull Clin Psychopharmacol , vol.19 , pp. 135-142
    • Basoglu, C.1    Ates, M.2    Algul, A.3    Ipcioglu, O.M.4    Gecici, O.5    Yilmaz, O.6
  • 68
    • 49849083142 scopus 로고    scopus 로고
    • Effect of folic acid combined with fluoxetine in patients with major depression on plasma homocysteine and vitamin B12, and serotonin levels in lymphocytes
    • Resler G, Lavie R, Campos J, Mata S, Urbina M, Garcia A, et al. Effect of folic acid combined with fluoxetine in patients with major depression on plasma homocysteine and vitamin B12, and serotonin levels in lymphocytes. Neuroimmunomodulation 2008;15:145-52.
    • (2008) Neuroimmunomodulation , vol.15 , pp. 145-152
    • Resler, G.1    Lavie, R.2    Campos, J.3    Mata, S.4    Urbina, M.5    Garcia, A.6
  • 69
    • 79953181959 scopus 로고    scopus 로고
    • No clear potentiation of antidepressant medication effects by folic acid and vitamin B12 in a large community sample
    • Christensen H, Aiken A, Batterham PJ, Walker J, Mackinnon AJ, Fenech M, et al. No clear potentiation of antidepressant medication effects by folic acid and vitamin B12 in a large community sample. J Affect Disord 2011;130:37-45. http://dx.doi.org/10.1016/j.jad.2010.07.029
    • (2011) J Affect Disord , vol.130 , pp. 37-45
    • Christensen, H.1    Aiken, A.2    Batterham, P.J.3    Walker, J.4    Mackinnon, A.J.5    Fenech, M.6
  • 70
    • 76949090568 scopus 로고    scopus 로고
    • The B-VITAGE trial: A randomized trial of homocysteine lowering treatment of depression in later life
    • Ford AH, Flicker L, McCaul K, van Bockxmeer F, Hegarty S, Hirani V, et al. The B-VITAGE trial: a randomized trial of homocysteine lowering treatment of depression in later life. Trials 2010;11:8. http://dx.doi.org/10.1186/1745-6215-11-8
    • (2010) Trials , vol.11 , pp. 8
    • Ford, A.H.1    Flicker, L.2    McCaul, K.3    van Bockxmeer, F.4    Hegarty, S.5    Hirani, V.6
  • 71
    • 79151477241 scopus 로고    scopus 로고
    • Genome-wide association study of recurrent early-onset major depressive disorder
    • Shi J, Potash JB, Knowles JA, Weissman MM, Coryell W, Scheftner WA, et al. Genome-wide association study of recurrent early-onset major depressive disorder. Mol Psychiatry 2011;16:193-201. http://dx.doi.org/10.1038/mp.2009.124
    • (2011) Mol Psychiatry , vol.16 , pp. 193-201
    • Shi, J.1    Potash, J.B.2    Knowles, J.A.3    Weissman, M.M.4    Coryell, W.5    Scheftner, W.A.6
  • 72
    • 79151475816 scopus 로고    scopus 로고
    • Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies
    • Shyn SI, Shi J, Kraft JB, Potash JB, Knowles JA, Weissman MM, et al. Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies. Mol Psychiatry 2011;16:202-15. http://dx.doi.org/10.1038/mp.2009.125
    • (2011) Mol Psychiatry , vol.16 , pp. 202-215
    • Shyn, S.I.1    Shi, J.2    Kraft, J.B.3    Potash, J.B.4    Knowles, J.A.5    Weissman, M.M.6
  • 73
    • 62849128600 scopus 로고    scopus 로고
    • Genome-wide association for major depressive disorder: A possible role for the presynaptic protein piccolo
    • Sullivan PF, de Geus EJ, Willemsen G, James MR, Smit JH, Zandbelt T, et al. Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Mol Psychiatry 2009;14:359-75. http://dx.doi.org/10.1038/mp.2008.125
    • (2009) Mol Psychiatry , vol.14 , pp. 359-375
    • Sullivan, P.F.1    de Geus, E.J.2    Willemsen, G.3    James, M.R.4    Smit, J.H.5    Zandbelt, T.6
  • 74
    • 69949184308 scopus 로고    scopus 로고
    • A genome-wide association study points to multiple loci that predict antidepressant drug treatment outcome in depression
    • Ising M, Lucae S, Binder EB, Bettecken T, Uhr M, Ripke S, et al. A genome-wide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. Arch Gen Psychiatry 2009;66:966-75.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 966-975
    • Ising, M.1    Lucae, S.2    Binder, E.B.3    Bettecken, T.4    Uhr, M.5    Ripke, S.6
  • 75
    • 77951779878 scopus 로고    scopus 로고
    • Genome-wide pharmacogenetics of antidepressant response in the GENDEP project
    • Uher R, Perroud N, Ng MY, Hauser J, Henigsberg N, Maier W, et al. Genome-wide pharmacogenetics of antidepressant response in the GENDEP project. Am J Psychiatry 2010;167:555-64. http://dx.doi.org/10.1176/appi.ajp.2009.09070932
    • (2010) Am J Psychiatry , vol.167 , pp. 555-564
    • Uher, R.1    Perroud, N.2    Ng, M.Y.3    Hauser, J.4    Henigsberg, N.5    Maier, W.6
  • 76
    • 33845887461 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: A HuGE review
    • Gilbody S, Lewis S, Lightfoot T. Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE review. Am J Epidemiol 2007;165:1-13. http://dx.doi.org/10.1093/aje/kwj347
    • (2007) Am J Epidemiol , vol.165 , pp. 1-13
    • Gilbody, S.1    Lewis, S.2    Lightfoot, T.3
  • 77
    • 33645527632 scopus 로고    scopus 로고
    • The thermolabile variant of MTHFR is associated with depression in the British Women's Heart and Health Study and a meta-analysis
    • Lewis SJ, Lawlor DA, Davey Smith G, Araya R, Timpson N, Day IN, et al. The thermolabile variant of MTHFR is associated with depression in the British Women's Heart and Health Study and a meta-analysis. Mol Psychiatry 2006;11:352-60. http://dx.doi.org/10.1038/sj.mp.4001790
    • (2006) Mol Psychiatry , vol.11 , pp. 352-360
    • Lewis, S.J.1    Lawlor, D.A.2    Davey Smith, G.3    Araya, R.4    Timpson, N.5    Day, I.N.6
  • 78
    • 56949085834 scopus 로고    scopus 로고
    • Polymorphic variants of genes encoding MTHFR, MTR, and MTHFD1 and the risk of depression in postmenopausal women in Poland
    • Slopien R, Jasniewicz K, Meczekalski B, Warenik-Szymankiewicz A, Lianeri M, Jagodzinski PP. Polymorphic variants of genes encoding MTHFR, MTR, and MTHFD1 and the risk of depression in postmenopausal women in Poland. Maturitas 2008;61:252-5.
    • (2008) Maturitas , vol.61 , pp. 252-255
    • Slopien, R.1    Jasniewicz, K.2    Meczekalski, B.3    Warenik-Szymankiewicz, A.4    Lianeri, M.5    Jagodzinski, P.P.6
  • 79
    • 84855476511 scopus 로고    scopus 로고
    • Folic acid supplementation during pregnancy may protect against depression 21 months after pregnancy, an effect modified by MTHFR C677T genotype
    • Lewis SJ, Araya R, Leary S, Smith GD, Ness A. Folic acid supplementation during pregnancy may protect against depression 21 months after pregnancy, an effect modified by MTHFR C677T genotype. Eur J Clin Nutr 2012;66:97-103. http://dx.doi.org/10.1038/ejcn.2011.136
    • (2012) Eur J Clin Nutr , vol.66 , pp. 97-103
    • Lewis, S.J.1    Araya, R.2    Leary, S.3    Smith, G.D.4    Ness, A.5
  • 80
    • 79956330532 scopus 로고    scopus 로고
    • MTHFR 677C→T genotype is associated with folate and homocysteine concentrations in a large, population-based, double-blind trial of folic acid supplementation
    • Crider KS, Zhu JH, Hao L, Yang QH, Yang TP, Gindler J, et al. MTHFR 677C→T genotype is associated with folate and homocysteine concentrations in a large, population-based, double-blind trial of folic acid supplementation. Am J Clin Nutr 2011;93:1365-72. http://dx.doi.org/10.3945/ajcn.110.004671
    • (2011) Am J Clin Nutr , vol.93 , pp. 1365-1372
    • Crider, K.S.1    Zhu, J.H.2    Hao, L.3    Yang, Q.H.4    Yang, T.P.5    Gindler, J.6
  • 81
    • 39049092670 scopus 로고    scopus 로고
    • Folate Augmentation of Treatment - Evaluation for Depression (FolATED): Protocol of a randomised controlled trial
    • Roberts SH, Bedson E, Hughes DA, Lloyd KR, Moat S, Pirmohamed M, et al. Folate Augmentation of Treatment - Evaluation for Depression (FolATED): protocol of a randomised controlled trial. BMC Psychiatry 2007;7:65. http://dx.doi.org/10.1186/1471-244X-7-65
    • (2007) BMC Psychiatry , vol.7 , pp. 65
    • Roberts, S.H.1    Bedson, E.2    Hughes, D.A.3    Lloyd, K.R.4    Moat, S.5    Pirmohamed, M.6
  • 82
    • 65749107876 scopus 로고    scopus 로고
    • Erratum: Folate Augumentation of Treatment - Evaluation for Depression (FolATED): Protocol of a randomised controlled trial
    • Roberts SH, Bedson E, Hughes DA, Lloyd KR, Menkes DB, Moat SJ, et al. Erratum: Folate Augumentation of Treatment - Evaluation for Depression (FolATED): protocol of a randomised controlled trial. BMC Psychiatry 2009;9:14. http://dx.doi.org/10.1186/1471-244X-9-14
    • (2009) BMC Psychiatry , vol.9 , pp. 14
    • Roberts, S.H.1    Bedson, E.2    Hughes, D.A.3    Lloyd, K.R.4    Menkes, D.B.5    Moat, S.J.6
  • 83
    • 84905007001 scopus 로고    scopus 로고
    • Data for the areas identified in the Wales spatial plan
    • Welsh Assembly Government, 2010 update, SB 103/2010
    • Welsh Assembly Government. Data for the areas identified in the Wales spatial plan, 2010 update. Statistical Bulletin 2010;SB 103/2010.
    • (2010) Statistical Bulletin
  • 88
    • 84905032442 scopus 로고    scopus 로고
    • British Pharmacopoeia, accessed March 2013
    • British Pharmacopoeia. URL: www.pharmacopoeia.co.uk (accessed March 2013).
  • 89
    • 0025610077 scopus 로고
    • Estimating integrals using quadrature methods with an application in pharmacokinetics
    • Bailer J, Peigorsch W. Estimating integrals using quadrature methods with an application in pharmacokinetics. Biometrics 1990;46:1201-11. http://dx.doi.org/10.2307/2532462
    • (1990) Biometrics , vol.46 , pp. 1201-1211
    • Bailer, J.1    Peigorsch, W.2
  • 90
    • 0018425438 scopus 로고
    • A new depression scale designed to be sensitive to change
    • Montgomery SA, Åsberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry 1979;134:382-9. http://dx.doi.org/10.1192/bjp.134.4.382
    • (1979) Br J Psychiatry , vol.134 , pp. 382-389
    • Montgomery, S.A.1    Åsberg, M.2
  • 91
    • 0003412410 scopus 로고
    • Clinical Global Impression (CGI, Rockville, MD: Department of Health, Education, and Welfare
    • Guy W. Clinical Global Impression (CGI). Taken from ECDEU Assessment Manual for Psychopharmacology. Rockville, MD: Department of Health, Education, and Welfare; 1976.
    • (1976) Taken From ECDEU Assessment Manual For Psychopharmacology
    • Guy, W.1
  • 92
    • 0030096228 scopus 로고    scopus 로고
    • A 12-Item Short-Form Health Survey: Construction of scales and preliminary tests of reliability and validity
    • Ware J Jr, Kosinski M, Keller SD. A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care 1996;34:220-33. http://dx.doi.org/10.1097/00005650-199603000-00003
    • (1996) Med Care , vol.34 , pp. 220-233
    • Ware Jr., J.1    Kosinski, M.2    Keller, S.D.3
  • 93
    • 0025688231 scopus 로고
    • EuroQol - a new facility for the measurement of health-related quality of life
    • EuroQol Group
    • EuroQol Group. EuroQol - a new facility for the measurement of health-related quality of life. Health Policy 1990;16:199-208.
    • (1990) Health Policy , vol.16 , pp. 199-208
  • 94
    • 0023244845 scopus 로고
    • The UKU side effect rating scale. A new comprehensive rating scale for psychotropic drugs and a cross-sectional study of side effects in neuroleptic-treated patients
    • Lingjaerde O, Ahlfors UG, Bech P, Dencker SJ, Elgen K. The UKU side effect rating scale. A new comprehensive rating scale for psychotropic drugs and a cross-sectional study of side effects in neuroleptic-treated patients. Acta Psychiatr Scand 1987;334(Suppl.):1-100. http://dx.doi.org/10.1111/j.1600-0447.1987.tb10566.x
    • (1987) Acta Psychiatr Scand , vol.334 , Issue.SUPPL. , pp. 1-100
    • Lingjaerde, O.1    Ahlfors, U.G.2    Bech, P.3    Dencker, S.J.4    Elgen, K.5
  • 95
    • 0022632510 scopus 로고
    • Concurrent and predictive validity of a self-reported measure of medication adherence
    • Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care 1986;24:67-74. http://dx.doi.org/10.1097/00005650-198601000-00007
    • (1986) Med Care , vol.24 , pp. 67-74
    • Morisky, D.E.1    Green, L.W.2    Levine, D.M.3
  • 99
    • 0029112074 scopus 로고
    • Antidepressants: Can we determine how quickly they work?
    • Gershon S. Antidepressants: can we determine how quickly they work? Psychopharmacol Bull 1995;31:21-2.
    • (1995) Psychopharmacol Bull , vol.31 , pp. 21-22
    • Gershon, S.1
  • 100
    • 33750694210 scopus 로고    scopus 로고
    • Early onset of selective serotonin reuptake inhibitor antidepressant action: Systematic review and meta-analysis
    • Taylor MJ, Freemantle N, Geddes JR, Bhagwagar Z. Early onset of selective serotonin reuptake inhibitor antidepressant action: systematic review and meta-analysis. Arch Gen Psychiatry 2006;63:1217-23. http://dx.doi.org/10.1001/archpsyc.63.11.1217
    • (2006) Arch Gen Psychiatry , vol.63 , pp. 1217-1223
    • Taylor, M.J.1    Freemantle, N.2    Geddes, J.R.3    Bhagwagar, Z.4
  • 101
    • 84905033205 scopus 로고    scopus 로고
    • Directive 2001/20/EC of European Parliament and the Council of 4 April 2001
    • European Parliament and Council of the European Union, Article 2 (Definitions). L121/35-7
    • European Parliament and Council of the European Union. Directive 2001/20/EC of European Parliament and the Council of 4 April 2001. Official Journal of European Union 2001; Article 2 (Definitions). L121/35-7.
    • (2001) Official Journal of European Union
  • 104
    • 0004277129 scopus 로고    scopus 로고
    • Medical Research Council, London: MRC
    • Medical Research Council. Good Research Practice. London: MRC; 2000.
    • (2000) Good Research Practice
  • 106
    • 0003767165 scopus 로고    scopus 로고
    • Wales Office for Research and Development in Health Social Care, Cardiff: Welsh Assembly Government
    • Wales Office for Research and Development in Health Social Care. Research Governance Framework for Health and Social Care in Wales. Cardiff: Welsh Assembly Government: 2001.
    • (2001) Research Governance Framework For Health and Social Care In Wales
  • 107
  • 108
    • 2642617783 scopus 로고    scopus 로고
    • Incomplete quality of life data in randomized trials: Missing items
    • Fayers PM, Curran D, Machin D. Incomplete quality of life data in randomized trials: missing items. Stat Med 1998;17:679-96. http://dx.doi.org/10.1002/(SICI)1097-0258(19980315/15)17:5/7%3C679::AID-SIM814%3E3.3.CO;2-O
    • (1998) Stat Med , vol.17 , pp. 679-696
    • Fayers, P.M.1    Curran, D.2    Machin, D.3
  • 110
    • 0025055144 scopus 로고
    • Analysis of serial measurements in medical research
    • Matthews JNS, Altman DG, Campbell MJ, Royston P. Analysis of serial measurements in medical research. BMJ 1990;300:230-5. http://dx.doi.org/10.1136/bmj.300.6719.230
    • (1990) BMJ , vol.300 , pp. 230-235
    • Matthews, J.N.S.1    Altman, D.G.2    Campbell, M.J.3    Royston, P.4
  • 112
    • 80755180389 scopus 로고    scopus 로고
    • National Institute for Health and Clinical Excellence, London: NICE
    • National Institute for Health and Clinical Excellence. Guide to the Methods of Technology Appraisal. London: NICE: 2008.
    • (2008) Guide to The Methods of Technology Appraisal
  • 113
    • 21044457536 scopus 로고    scopus 로고
    • A randomised controlled trial to compare the cost-effectiveness of tricyclic antidepressants, selective serotonin reuptake inhibitors and lofepramine
    • Peveler R, Kendrick T, Buxton M, Longworth L, Baldwin D, Moore M, et al. A randomised controlled trial to compare the cost-effectiveness of tricyclic antidepressants, selective serotonin reuptake inhibitors and lofepramine. Health Technol Assess 2005;9(16).
    • (2005) Health Technol Assess , vol.9 , Issue.16
    • Peveler, R.1    Kendrick, T.2    Buxton, M.3    Longworth, L.4    Baldwin, D.5    Moore, M.6
  • 116
    • 79961185164 scopus 로고    scopus 로고
    • Department of Health, London: DH, accessed March 2013
    • Department of Health. NHS Reference Costs 2009-10. London: DH; 2010. URL: www.dh.gov.uk/en/Publicationsandstatistics/Publications/PublicationsPolicyAndGuidance/DH_123459 (accessed March 2013).
    • (2010) NHS Reference Costs 2009-10
  • 117
    • 84655168968 scopus 로고    scopus 로고
    • Department of Health, London: DH, accessed March 2013
    • Department of Health. Prescription Cost Analysis, England 2010. London: DH; 2011. URL: www.ic.nhs.uk/pubs/prescostanalysis2010 (accessed March 2013).
    • (2011) Prescription Cost Analysis, England 2010
  • 118
    • 69749086196 scopus 로고    scopus 로고
    • Estimating drug costs in economic evaluations in Ireland and the UK: An analysis of practice and research recommendations
    • Hughes DA, Tilson L, Drummond M. Estimating drug costs in economic evaluations in Ireland and the UK: an analysis of practice and research recommendations. Pharmacoeconomics 2009;27:635-43. http://dx.doi.org/10.2165/10899570-000000000-00000
    • (2009) Pharmacoeconomics , vol.27 , pp. 635-643
    • Hughes, D.A.1    Tilson, L.2    Drummond, M.3
  • 119
    • 42149127173 scopus 로고    scopus 로고
    • University of Kent at Canterbury: Personal Social Services Research Unit
    • Curtis L. Unit Costs of Health and Social Care 2010. University of Kent at Canterbury: Personal Social Services Research Unit; 2010.
    • (2010) Unit Costs of Health and Social Care 2010
    • Curtis, L.1
  • 120
    • 84904984113 scopus 로고    scopus 로고
    • NHS Direct, London: NHSD, accessed March 2013
    • NHS Direct. Board Scorecard 2010/11. London: NHSD; 2011. URL: www.nhsdirect.nhs.uk/CorporateInformation/MinutesOfMeetings/BoardMeetingPapers2011//media/Files/BoardPapers/February2011/Item_71_Board_Scorecard.ashx (accessed March 2013).
    • (2011) Board Scorecard 2010/11
  • 122
    • 4644244422 scopus 로고    scopus 로고
    • Estimation of a preference-based index from the SF-12
    • Brazier JE, Roberts JR. Estimation of a preference-based index from the SF-12. Med Care 2004;42:851-9.
    • (2004) Med Care , vol.42 , pp. 851-859
    • Brazier, J.E.1    Roberts, J.R.2
  • 123
    • 0031841683 scopus 로고    scopus 로고
    • A psychometric evaluation of the Beck Depression Inventory-II
    • Dozois DJA, Dobson KS, Ahnberg JL. A psychometric evaluation of the Beck Depression Inventory-II. Psychol Assess 1998;10:83-9. http://dx.doi.org/10.1037//1040-3590.10.2.83
    • (1998) Psychol Assess , vol.10 , pp. 83-89
    • Dozois, D.J.A.1    Dobson, K.S.2    Ahnberg, J.L.3
  • 124
    • 79960014593 scopus 로고    scopus 로고
    • Review of statistical methods for analysing healthcare resources and costs
    • Mihaylova B, Briggs A, O'Hagan A, Thompson S. Review of statistical methods for analysing healthcare resources and costs. Health Econ 2011;20:897-916. http://dx.doi.org/10.1002/hec.1653
    • (2011) Health Econ , vol.20 , pp. 897-916
    • Mihaylova, B.1    Briggs, A.2    O'Hagan, A.3    Thompson, S.4
  • 126
    • 19444368977 scopus 로고    scopus 로고
    • Estimating mean QALYs in trial-based cost-effectiveness analysis: The importance of controlling for baseline utility
    • Manca A, Hawkins N, Sculpher MJ. Estimating mean QALYs in trial-based cost-effectiveness analysis: the importance of controlling for baseline utility. Health Econ 2005;14:487-96. http://dx.doi.org/10.1002/hec.944
    • (2005) Health Econ , vol.14 , pp. 487-496
    • Manca, A.1    Hawkins, N.2    Sculpher, M.J.3
  • 127
    • 70349829518 scopus 로고    scopus 로고
    • Investigation of inter-individual variability of the one-carbon folate pathway: A bioinformatic and genetic review
    • Carr DF, Whiteley G, Alfirevic A, Pirmohamed M. Investigation of inter-individual variability of the one-carbon folate pathway: a bioinformatic and genetic review. Pharmacogenom J 2009; 9:291-305. http://dx.doi.org/10.1038/tpj.2009.29
    • (2009) Pharmacogenom J , vol.9 , pp. 291-305
    • Carr, D.F.1    Whiteley, G.2    Alfirevic, A.3    Pirmohamed, M.4
  • 128
    • 0038314480 scopus 로고    scopus 로고
    • Folate, vitamin B12, homocysteine, and the MTHFR 677C→T polymorphism in anxiety and depression: The Hordaland Homocysteine Study
    • Bjelland I, Tell GS, Vollset SE, Refsum H, Ueland PM. Folate, vitamin B12, homocysteine, and the MTHFR 677C→T polymorphism in anxiety and depression: the Hordaland Homocysteine Study. Arch Gen Psychiatry 2003;60:618-26. http://dx.doi.org/10.1001/archpsyc.60.6.618
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 618-626
    • Bjelland, I.1    Tell, G.S.2    Vollset, S.E.3    Refsum, H.4    Ueland, P.M.5
  • 129
    • 33846018546 scopus 로고    scopus 로고
    • Nonsynonymous polymorphisms in genes in the one-carbon metabolism pathway and associations with colorectal cancer
    • Koushik A, Kraft P, Fuchs CS, Hankinson SE, Willett WC, Giovannucci EL, et al. Nonsynonymous polymorphisms in genes in the one-carbon metabolism pathway and associations with colorectal cancer. Cancer Epidemiol Biomarkers Prev 2006;15:2408-17. http://dx.doi.org/10.1158/1055-9965.EPI-06-0624
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 2408-2417
    • Koushik, A.1    Kraft, P.2    Fuchs, C.S.3    Hankinson, S.E.4    Willett, W.C.5    Giovannucci, E.L.6
  • 130
    • 77954469742 scopus 로고    scopus 로고
    • A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk
    • Levine AJ, Figueiredo JC, Lee W, Conti DV, Kennedy K, Duggan DJ, et al. A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 2010;19:1812-21. http://dx.doi.org/10.1158/1055-9965.EPI-10-0151
    • (2010) Cancer Epidemiol Biomarkers Prev , vol.19 , pp. 1812-1821
    • Levine, A.J.1    Figueiredo, J.C.2    Lee, W.3    Conti, D.V.4    Kennedy, K.5    Duggan, D.J.6
  • 131
    • 34247478510 scopus 로고    scopus 로고
    • Genetic polymorphisms in the one-carbon metabolism pathway and breast cancer risk: Population-based case-control study and meta-analyses
    • Lissowska J, Gaudet MM, Brinton LA, Chanock SJ, Peplonska B, Welch R, et al. Genetic polymorphisms in the one-carbon metabolism pathway and breast cancer risk: population-based case-control study and meta-analyses. Int J Cancer 2007;120:2696-703. http://dx.doi.org/10.1002/ijc.22604
    • (2007) Int J Cancer , vol.120 , pp. 2696-2703
    • Lissowska, J.1    Gaudet, M.M.2    Brinton, L.A.3    Chanock, S.J.4    Peplonska, B.5    Welch, R.6
  • 132
    • 34247326362 scopus 로고    scopus 로고
    • Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer
    • Moore LE, Malats N, Rothman N, Real FX, Kogevinas M, Karami S, et al. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer. Int J Cancer 2007;120:2452-8. http://dx.doi.org/10.1002/ijc.22565
    • (2007) Int J Cancer , vol.120 , pp. 2452-2458
    • Moore, L.E.1    Malats, N.2    Rothman, N.3    Real, F.X.4    Kogevinas, M.5    Karami, S.6
  • 134
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005;21:263-5.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 135
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007;81:559-75. http://dx.doi.org/10.1086/519795
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Ferreira, M.A.5    Bender, D.6
  • 138
    • 27844437085 scopus 로고    scopus 로고
    • Assessing Health Economics of Anti-Depressants team. Comparison of general practitioner records and patient self-report questionnaires for estimation of costs
    • Mistry H, Buxton M, Longworth L, Chatwin J, Peveler R. Assessing Health Economics of Anti-Depressants team. Comparison of general practitioner records and patient self-report questionnaires for estimation of costs. Eur J Health Econ 2005;6:261-6.
    • (2005) Eur J Health Econ , vol.6 , pp. 261-266
    • Mistry, H.1    Buxton, M.2    Longworth, L.3    Chatwin, J.4    Peveler, R.5
  • 139
    • 0031872695 scopus 로고    scopus 로고
    • Comparison of the MOS short form-12 (SF-12) health status questionnaire with the SF36 in patients with rhematoid arthritis
    • Hurst NP, Ruta DA, Kind P. Comparison of the MOS short form-12 (SF-12) health status questionnaire with the SF36 in patients with rhematoid arthritis. Br J Rheumatol 1998;37:862-9. http://dx.doi.org/10.1093/rheumatology/37.8.862
    • (1998) Br J Rheumatol , vol.37 , pp. 862-869
    • Hurst, N.P.1    Ruta, D.A.2    Kind, P.3
  • 140
    • 51949111034 scopus 로고    scopus 로고
    • The relationship between quality of life and levels of hopelessness and depression in palliative care
    • Mystakidou K, Tsilika E, Parpa E, Pathiaki M, Galanos A, Vlahos L. The relationship between quality of life and levels of hopelessness and depression in palliative care. Depress Anxiety 2008;25:730-6. http://dx.doi.org/10.1002/da.20319
    • (2008) Depress Anxiety , vol.25 , pp. 730-736
    • Mystakidou, K.1    Tsilika, E.2    Parpa, E.3    Pathiaki, M.4    Galanos, A.5    Vlahos, L.6
  • 141
    • 33750728400 scopus 로고    scopus 로고
    • High - but not low-dose folic acid improves endothelial function in coronary artery disease
    • Moat SJ, Madhavan A, Taylor SY, Payne N, Allen RH, Stabler SP, et al. High - but not low-dose folic acid improves endothelial function in coronary artery disease. Eur J Clin Invest 2006; 36:850-9. http://dx.doi.org/10.1111/j.1365-2362.2006.01739.x
    • (2006) Eur J Clin Invest , vol.36 , pp. 850-859
    • Moat, S.J.1    Madhavan, A.2    Taylor, S.Y.3    Payne, N.4    Allen, R.H.5    Stabler, S.P.6
  • 142
    • 0035061971 scopus 로고    scopus 로고
    • The death of cost-minimization analysis?
    • Briggs AH, O'Brien BJ. The death of cost-minimization analysis? Health Econ 2001;10:179-84. http://dx.doi.org/10.1002/hec.584
    • (2001) Health Econ , vol.10 , pp. 179-184
    • Briggs, A.H.1    O'Brien, B.J.2
  • 143
    • 84870549563 scopus 로고    scopus 로고
    • Cost-minimisation analysis versus cost-effectiveness analysis - revisited
    • Dakin H, Wordsworth S. Cost-minimisation analysis versus cost-effectiveness analysis - revisited. Health Econ 2013;22:22-34. http://dx.doi.org/10.1002/hec.1812
    • (2013) Health Econ , vol.22 , pp. 22-34
    • Dakin, H.1    Wordsworth, S.2
  • 144
    • 84971580244 scopus 로고
    • Statistics notes: Absence of evidence is not evidence of absence
    • Altman DG, Bland JM. Statistics notes: absence of evidence is not evidence of absence. BMJ 1995;311:485. http://dx.doi.org/10.1136/bmj.311.7003.485
    • (1995) BMJ , vol.311 , pp. 485
    • Altman, D.G.1    Bland, J.M.2
  • 145
    • 0033044884 scopus 로고    scopus 로고
    • The irrelevance of inference: A decision-making approach to the stochastic evaluation of health care technologies
    • Claxton K. The irrelevance of inference: a decision-making approach to the stochastic evaluation of health care technologies. J Health Econ 1999;18:341-64. http://dx.doi.org/10.1016/S0167-6296(98)00039-3
    • (1999) J Health Econ , vol.18 , pp. 341-364
    • Claxton, K.1
  • 146
    • 44349171715 scopus 로고    scopus 로고
    • The clinical relevance of changes in the Montgomery-Åsberg Depression Rating Scale using the minimum clinically important difference approach
    • Duru G, Fantino B. The clinical relevance of changes in the Montgomery-Åsberg Depression Rating Scale using the minimum clinically important difference approach. Curr Med Res Opin 2008;24:1329-35. http://dx.doi.org/10.1185/030079908X291958
    • (2008) Curr Med Res Opin , vol.24 , pp. 1329-1335
    • Duru, G.1    Fantino, B.2
  • 147
    • 84861819926 scopus 로고    scopus 로고
    • Glutamate carboxypeptidase II gene polymorphisms and neural tube defects in a high-risk Chinese population
    • Xie H, Guo J, Wang J, Wang F, Zhao H, Liu C, et al. Glutamate carboxypeptidase II gene polymorphisms and neural tube defects in a high-risk Chinese population. Metab Brain Dis 2012;27:59-65. http://dx.doi.org/10.1007/s11011-011-9272-8
    • (2012) Metab Brain Dis , vol.27 , pp. 59-65
    • Xie, H.1    Guo, J.2    Wang, J.3    Wang, F.4    Zhao, H.5    Liu, C.6
  • 148
    • 0034703861 scopus 로고    scopus 로고
    • Glutamate carboxypeptidase II: A polymorphism associated with lower levels of serum folate and hyperhomocysteinemia
    • Devlin AM, Ling EH, Peerson JM, Fernando S, Clarke R, Smith AD, et al. Glutamate carboxypeptidase II: a polymorphism associated with lower levels of serum folate and hyperhomocysteinemia. Hum Mol Genet 2000;9:2837-44. http://dx.doi.org/10.1093/hmg/9.19.2837
    • (2000) Hum Mol Genet , vol.9 , pp. 2837-2844
    • Devlin, A.M.1    Ling, E.H.2    Peerson, J.M.3    Fernando, S.4    Clarke, R.5    Smith, A.D.6
  • 149
    • 79958158233 scopus 로고    scopus 로고
    • The folate hydrolase 1561C>T polymorphism is associated with depressive symptoms in Puerto Rican adults
    • Ye X, Lai CQ, Crott JW, Troen AM, Ordovas JM, Tucker KL. The folate hydrolase 1561C>T polymorphism is associated with depressive symptoms in Puerto Rican adults. Psychosom Med 2011;73:385-92. http://dx.doi.org/10.1097/PSY.0b013e31821a1ab4
    • (2011) Psychosom Med , vol.73 , pp. 385-392
    • Ye, X.1    Lai, C.Q.2    Crott, J.W.3    Troen, A.M.4    Ordovas, J.M.5    Tucker, K.L.6
  • 150
    • 34547869292 scopus 로고    scopus 로고
    • Relations of glutamate carboxypeptidase II (GCPII) polymorphisms to folate and homocysteine concentrations and to scores of cognition, anxiety, and depression in a homogeneous Norwegian population: The Hordaland Homocysteine Study
    • Halsted CH, Wong DH, Peerson JM, Warden CH, Refsum H, Smith AD, et al. Relations of glutamate carboxypeptidase II (GCPII) polymorphisms to folate and homocysteine concentrations and to scores of cognition, anxiety, and depression in a homogeneous Norwegian population: the Hordaland Homocysteine Study. Am J Clin Nutr 2007;86:514-21.
    • (2007) Am J Clin Nutr , vol.86 , pp. 514-521
    • Halsted, C.H.1    Wong, D.H.2    Peerson, J.M.3    Warden, C.H.4    Refsum, H.5    Smith, A.D.6
  • 152
    • 0031020197 scopus 로고    scopus 로고
    • Dominant inheritance of isolated hypermethioninemia is associated with a mutation in the human methionine adenosyltransferase 1A gene
    • Chamberlin ME, Ubagai T, Mudd SH, Levy HL, Chou JY. Dominant inheritance of isolated hypermethioninemia is associated with a mutation in the human methionine adenosyltransferase 1A gene. Am J Hum Genet 1997;60:540-6.
    • (1997) Am J Hum Genet , vol.60 , pp. 540-546
    • Chamberlin, M.E.1    Ubagai, T.2    Mudd, S.H.3    Levy, H.L.4    Chou, J.Y.5
  • 153
    • 0032477711 scopus 로고    scopus 로고
    • Normal brain myelination in a patient homozygous for a mutation that encodes a severely truncated methionine adenosyltransferase I/III
    • Hazelwood S, Bernardini I, Shotelersuk V, Tangerman A, Guo J, Mudd H, et al. Normal brain myelination in a patient homozygous for a mutation that encodes a severely truncated methionine adenosyltransferase I/III. Am J Med Genet 1998;75:395-400. http://dx.doi.org/10.1002/(SICI)1096-8628(19980203)75:4%3C395::AID-AJMG9%3E3.0.CO;2-P
    • (1998) Am J Med Genet , vol.75 , pp. 395-400
    • Hazelwood, S.1    Bernardini, I.2    Shotelersuk, V.3    Tangerman, A.4    Guo, J.5    Mudd, H.6
  • 154
    • 77957151650 scopus 로고    scopus 로고
    • Trajectories of change in depression severity during treatment with antidepressants
    • Uher R, Muthen B, Souery D, Mors O, Jaracz J, Aitchison KJ, et al. Trajectories of change in depression severity during treatment with antidepressants. Psychol Med 2010;40:1367-77. http://dx.doi.org/10.1017/S0033291709991528
    • (2010) Psychol Med , vol.40 , pp. 1367-1377
    • Uher, R.1    Muthen, B.2    Souery, D.3    Mors, O.4    Jaracz, J.5    Aitchison, K.J.6
  • 155
    • 0036152658 scopus 로고    scopus 로고
    • Severity of depression and response to antidepressants and placebo: An analysis of the Food and Drug Administration database
    • Khan A, Leventhal RM, Khan SR, Brown WA. Severity of depression and response to antidepressants and placebo: An analysis of the Food and Drug Administration database. J Clin Psychopharmacol 2002;22:40-5. http://dx.doi.org/10.1097/00004714-200202000-00007
    • (2002) J Clin Psychopharmacol , vol.22 , pp. 40-45
    • Khan, A.1    Leventhal, R.M.2    Khan, S.R.3    Brown, W.A.4
  • 156
    • 0034855603 scopus 로고    scopus 로고
    • Antidepressant use in clinical practice: Efficacy v. effectiveness
    • Donoghue J, Hylan TR. Antidepressant use in clinical practice: efficacy v. effectiveness. Br J Psychiatry 2001;179:s9-17. http://dx.doi.org/10.1192/bjp.179.42.s9
    • (2001) Br J Psychiatry , vol.179
    • Donoghue, J.1    Hylan, T.R.2
  • 157
    • 77957602102 scopus 로고    scopus 로고
    • Cerebral folate deficiency
    • Hyland K, Shoffner J, Heales SJ. Cerebral folate deficiency. Inherit Metab Dis 2010;33:563-70. http://dx.doi.org/10.1007/s10545-010-9159-6
    • (2010) Inherit Metab Dis , vol.33 , pp. 563-570
    • Hyland, K.1    Shoffner, J.2    Heales, S.J.3
  • 158
    • 0032938097 scopus 로고    scopus 로고
    • Blood-brain barrier transport of reduced folic acid
    • Wu D, Partridge WM. Blood-brain barrier transport of reduced folic acid. Pharm Res 2009;16:415-19.
    • (2009) Pharm Res , vol.16 , pp. 415-419
    • Wu, D.1    Partridge, W.M.2
  • 159
    • 35948971448 scopus 로고    scopus 로고
    • Novel therapeutics for depression: L-methylfolate as a trimonamine modulator and antidepressant-augmenting agent
    • Stahl SM. Novel therapeutics for depression: L-methylfolate as a trimonamine modulator and antidepressant-augmenting agent. CNS Spectr 2007;12:739-44.
    • (2007) CNS Spectr , vol.12 , pp. 739-744
    • Stahl, S.M.1
  • 160
    • 0036140785 scopus 로고    scopus 로고
    • Folic acid improves endothelial function in coronary artery disease via mechanism(s) largely independent of homocysteine lowering
    • Doshi SN, McDowell IFW, Moat SJ, Payne N, Durant HJ, Lewis MJ, et al. Folic acid improves endothelial function in coronary artery disease via mechanism(s) largely independent of homocysteine lowering. Circulation 2002;105:22-6.
    • (2002) Circulation , vol.105 , pp. 22-26
    • Doshi, S.N.1    McDowell, I.F.W.2    Moat, S.J.3    Payne, N.4    Durant, H.J.5    Lewis, M.J.6
  • 161
    • 72749125429 scopus 로고    scopus 로고
    • Folate in depression: Efficacy, safety, differences in formulations and clinical issues
    • Fava M, Mischoulon D. Folate in depression: efficacy, safety, differences in formulations and clinical issues. J Clin Psychiatr 2009;70(Suppl. 5):12-17. http://dx.doi.org/10.4088/JCP.8157su1c.03
    • (2009) J Clin Psychiatr , vol.70 , Issue.SUPPL. 5 , pp. 12-17
    • Fava, M.1    Mischoulon, D.2
  • 162
    • 0029848516 scopus 로고    scopus 로고
    • How safe are folic acid supplements?
    • Campbell NR. How safe are folic acid supplements? Arch Intern Med 1996;156:1638-44. http://dx.doi.org/10.1001/archinte.156.15.1638
    • (1996) Arch Intern Med , vol.156 , pp. 1638-1644
    • Campbell, N.R.1
  • 163
    • 33846102164 scopus 로고    scopus 로고
    • Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification
    • Morris MS, Jacques PF, Rosenberg IH, Selhub J. Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification. Am J Clin Nutr 2007;85:193-200.
    • (2007) Am J Clin Nutr , vol.85 , pp. 193-200
    • Morris, M.S.1    Jacques, P.F.2    Rosenberg, I.H.3    Selhub, J.4
  • 165
    • 84905035377 scopus 로고    scopus 로고
    • North Wales Organisation for Randomised Trials in Health, Bangor: NWORTH
    • North Wales Organisation for Randomised Trials in Health. Standard Operating Procedure for Statistics (NWORTH 5.02). Bangor: NWORTH: 2010.
    • (2010) Standard Operating Procedure For Statistics (NWORTH 5.02)
  • 166
    • 58249102250 scopus 로고    scopus 로고
    • Economic evaluation alongside pragmatic randomised trials: Developing a standard operating procedure for clinical trials units
    • Edwards RT, Hounsome B, Linck P, Russell IT. Economic evaluation alongside pragmatic randomised trials: developing a standard operating procedure for clinical trials units. Trials 2008;9:64. http://dx.doi.org/10.1186/1745-6215-9-64
    • (2008) Trials , vol.9 , pp. 64
    • Edwards, R.T.1    Hounsome, B.2    Linck, P.3    Russell, I.T.4
  • 167
    • 84862589387 scopus 로고    scopus 로고
    • Mode of data elicitation, acquisition and response to surveys: A systematic review
    • Hood K, Robling M, Russell IT, et al. Mode of data elicitation, acquisition and response to surveys: a systematic review. Health Technol Assess 2012;16(27).
    • (2012) Health Technol Assess , vol.16 , Issue.27
    • Hood, K.1    Robling, M.2    Russell, I.T.3
  • 169
    • 0014254846 scopus 로고
    • Probability plotting methods for the analysis of data
    • Gnanadesikan R, Wilk MB. Probability plotting methods for the analysis of data. Biometrika 1965;55:1-17.
    • (1965) Biometrika , vol.55 , pp. 1-17
    • Gnanadesikan, R.1    Wilk, M.B.2
  • 170
    • 0000898845 scopus 로고
    • An analysis of variance test for normality
    • Shapiro SS, Wilk MB. An analysis of variance test for normality. Biometrika 1965;52:591-611. http://dx.doi.org/10.2307/2333709
    • (1965) Biometrika , vol.52 , pp. 591-611
    • Shapiro, S.S.1    Wilk, M.B.2
  • 171
    • 84950652331 scopus 로고
    • Approximate analysis of variance test for normality
    • Shapiro SS, Francia RS. Approximate analysis of variance test for normality. J Am Stat Assoc 1972;67:215-25. http://dx.doi.org/10.2307/2284728
    • (1972) J Am Stat Assoc , vol.67 , pp. 215-225
    • Shapiro, S.S.1    Francia, R.S.2
  • 172
    • 51149121441 scopus 로고    scopus 로고
    • Subgroups and heterogeneity in cost-effectiveness analysis
    • Sculpher M. Subgroups and heterogeneity in cost-effectiveness analysis. Pharmacoeconomics 2008;26:799-806. http://dx.doi.org/10.2165/00019053-200826090-00009
    • (2008) Pharmacoeconomics , vol.26 , pp. 799-806
    • Sculpher, M.1
  • 174
    • 84905032443 scopus 로고    scopus 로고
    • Using randomized experiments
    • Wholey JS, Hatry HP, Newcomer KE, editors, San Francisco, CA: Jossey-Bass
    • St Pierre RG. Using randomized experiments. In Wholey JS, Hatry HP, Newcomer KE, editors. Handbook of Practical Program Evaluation. San Francisco, CA: Jossey-Bass; 2004. p. 150.
    • (2004) Handbook of Practical Program Evaluation , pp. 150
    • St Pierre, R.G.1
  • 175
    • 37749022060 scopus 로고    scopus 로고
    • How often do UK primary care trials face recruitment delays?
    • Bower P, Wilson S, Mathers N. How often do UK primary care trials face recruitment delays? Fam Pract 2007;24:601-3. http://dx.doi.org/10.1093/fampra/cmm051
    • (2007) Fam Pract , vol.24 , pp. 601-603
    • Bower, P.1    Wilson, S.2    Mathers, N.3
  • 176
    • 33744981438 scopus 로고    scopus 로고
    • What influences recruitment to randomised controlled trials? A review of trials funded by two UK funding agencies
    • McDonald AM, Knight RC, Campbell MK, Entwistle VA, Grant AM, Cook JA, et al. What influences recruitment to randomised controlled trials? A review of trials funded by two UK funding agencies. Trials 2006;7:9.
    • (2006) Trials , vol.7 , pp. 9
    • McDonald, A.M.1    Knight, R.C.2    Campbell, M.K.3    Entwistle, V.A.4    Grant, A.M.5    Cook, J.A.6
  • 178
    • 33748476309 scopus 로고    scopus 로고
    • Increasing recruitment to randomised trials: A review of randomised controlled trials
    • Watson JM, Torgerson DJ. Increasing recruitment to randomised trials: A review of randomised controlled trials. BMC Med Res Method 2006;6:34.
    • (2006) BMC Med Res Method , vol.6 , pp. 34
    • Watson, J.M.1    Torgerson, D.J.2
  • 180
    • 79952460269 scopus 로고    scopus 로고
    • Using a business model approach and marketing techniques for recruitment to clinical trials
    • McDonald AM, Treweek S, Shakur H, Free C, Knight R, Speed C, et al. Using a business model approach and marketing techniques for recruitment to clinical trials. Trials 2011;12:74. http://dx.doi.org/10.1186/1745-6215-12-74
    • (2011) Trials , vol.12 , pp. 74
    • McDonald, A.M.1    Treweek, S.2    Shakur, H.3    Free, C.4    Knight, R.5    Speed, C.6
  • 181
    • 77954205896 scopus 로고    scopus 로고
    • A systematic review of models to predict recruitment to multicentre clinical trials
    • Barnard KD, Dent L, Cook A. A systematic review of models to predict recruitment to multicentre clinical trials. BMC Med Res Method 2010;10:63. http://dx.doi.org/10.1186/1471-2288-10-63
    • (2010) BMC Med Res Method , vol.10 , pp. 63
    • Barnard, K.D.1    Dent, L.2    Cook, A.3
  • 182
    • 70349529648 scopus 로고    scopus 로고
    • Improving recruitment to health research in primary care
    • Bower P, Wallace P, Ward E, Graffy J, Miller J, Delaney B, et al. Improving recruitment to health research in primary care. Fam Pract 2009;26:391-7. http://dx.doi.org/10.1093/fampra/cmp037
    • (2009) Fam Pract , vol.26 , pp. 391-397
    • Bower, P.1    Wallace, P.2    Ward, E.3    Graffy, J.4    Miller, J.5    Delaney, B.6
  • 183
    • 62849085021 scopus 로고    scopus 로고
    • Recruitment of practices in primary care research: The long and the short of it
    • Goodyear-Smith F, York D, Petousis-Harris H, Turner N, Copp J, Kerse N, et al. Recruitment of practices in primary care research: the long and the short of it. Fam Pract 2009;26:128-36. http://dx.doi.org/10.1093/fampra/cmp015
    • (2009) Fam Pract , vol.26 , pp. 128-136
    • Goodyear-Smith, F.1    York, D.2    Petousis-Harris, H.3    Turner, N.4    Copp, J.5    Kerse, N.6
  • 184
    • 79959203374 scopus 로고    scopus 로고
    • The UK clinical research network: Has it been a success for dermatology clinical trials?
    • Thomas KS, Koller K, Foster K, Perdue J, Charlesworth L, Chalmers JR. The UK clinical research network: has it been a success for dermatology clinical trials? Trials 2011;12:153. http://dx.doi.org/10.1186/1745-6215-12-153
    • (2011) Trials , vol.12 , pp. 153
    • Thomas, K.S.1    Koller, K.2    Foster, K.3    Perdue, J.4    Charlesworth, L.5    Chalmers, J.R.6
  • 185
    • 84904981158 scopus 로고    scopus 로고
    • National Institute for Social Care and Health Research. NISCHR Clinical Research Centre (CRC, accessed March 2013
    • National Institute for Social Care and Health Research. NISCHR Clinical Research Centre (CRC). 2011. URL: www.wales.nhs.uk/sites3/page.cfm?orgid=952&52012 (accessed March 2013).
    • (2011)
  • 186
    • 28244495107 scopus 로고    scopus 로고
    • An evaluation of the introduction of Clinical Trial Officer roles into the cancer clinical trial setting in the UK
    • Cox K AM, Wilson E, Elkan R. An evaluation of the introduction of Clinical Trial Officer roles into the cancer clinical trial setting in the UK. Eur J Cancer Care 2005;14:448-56. http://dx.doi.org/10.1111/j.1365-2354.2005.00611.x
    • (2005) Eur J Cancer Care , vol.14 , pp. 448-456
    • Cox, K.A.M.1    Wilson, E.2    Elkan, R.3
  • 187
    • 79955873950 scopus 로고    scopus 로고
    • Strengthening clinical cancer research in the United Kingdom
    • Stead M, Cameron D, Lester N, Parmar M, Haward R, Kaplan R, et al. Strengthening clinical cancer research in the United Kingdom. Br J Cancer 2011;104:1529-34. http://dx.doi.org/10.1038/bjc.2011.69
    • (2011) Br J Cancer , vol.104 , pp. 1529-1534
    • Stead, M.1    Cameron, D.2    Lester, N.3    Parmar, M.4    Haward, R.5    Kaplan, R.6


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