Improving recruitment to health research in primary care

Family Practice

Volumn 26, Issue 5, 2009, Pages 391-397

  Bower, Peter ^a   Wallace, Paul ^b   Ward, Elaine ^b   Graffy, Jonathan ^c   Miller, Julia ^a   Delaney, Brendan ^d   Kinmonth, Ann Louise ^c  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b United Kingdom Clinical Research Network   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Public health; Randomized controlled trial; Researchers

Indexed keywords

BEHAVIOR CHANGE; CLINICAL STUDY; DOCTOR PATIENT RELATION; ELECTRONIC MEDICAL RECORD; EVIDENCE BASED PRACTICE; GENERAL PRACTICE; GENERAL PRACTITIONER; HEALTH SERVICE; HUMAN; MEDICAL RESEARCH; METHODOLOGY; OUTCOME ASSESSMENT; PATIENT CARE; PATIENT INFORMATION; PATIENT SELECTION; PRIMARY MEDICAL CARE; QUALITATIVE RESEARCH; REVIEW;

ELECTRONIC HEALTH RECORDS; HEALTH SERVICES RESEARCH; HUMANS; ORGANIZATIONAL CULTURE; PATIENT SELECTION; PRIMARY HEALTH CARE; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 70349529648     PISSN: 02632136     EISSN: 14602229     Source Type: Journal    
DOI: 10.1093/fampra/cmp037     Document Type: Review

References (49)

1. Department of Health. Best Research for Best Health - a New National Health Research Strategy. London: Department of Health, 2006.
2. Ross S, Grant A, Counsell C, Gillespie W, Russell I, Prescott R. Barriers to participation in randomised controlled trials: A systematic review. J Clin Epidemiol 1999; 52: 1143-1156.
3. McDonald A, Knight R, Campbell M et al. What influences recruitment to randomised controlled trials? A review of trials funded by two UK funding agencies. Trials 2006; 7: 9.
4. Bower P, Wilson S, Mathers N. How often do UK primary care trials face recruitment delays? Fam Pract 2007; 24: 601-603.
5. Lovato L, Hill K, Hertert S, Hunninghake D, Probstfield J. Recruitment for controlled clinical trials: Literature summary and annotated bibliography. Control Clin Trials 1997; 18: 328-357.
6. Raftery J, Bryant J, Powell J, Kerr C, Hawker S. Payment to healthcare professionals for patient recruitment to trials: Systematic review and qualitative study. Health Technol Assess 2008; 12 (10).
7. Prescott R, Counsell C, Gillespie W et al. Factors that limit the quality, number and progress of randomised controlled trials. Health Technol Assess 1999; 3 (20).
8. Watson J, Torgerson D. Increasing recruitment to randomised trials: A review of randomised controlled trials. BMC Med Res Methodol 2006; 6 (34).
9. Patel M, Doku V, Tennakoon L. Challenges in recruitment of research participants. Adv Psychiatr Treat 2003; 9: 229-238.
10. Gill T, McGloin J, Gahbauer E, Shepard D, Bianco L. Two recruitment strategies for a clinical trial of physically frail community-living older persons. J Am Geriartr Soc 2001; 49: 1039-1045.
11. van Der Wouden J, Blankenstein A, Huibers M, Van der Windt D, Stalman W, Verhagen A. Survey among 78 studies showed that Lasagna's law holds in Dutch primary care research. J Clin Epidemiol 2007; 60: 819-824.
12. Wilson S, Delaney B, Roalfe A et al. Randomised controlled trials in primary care: Case study. Br Med J 2000; 321: 24-27.
13. Rendell J, Merritt R, Geddes J. Incentives and disincentives to participation by clinicians in randomised controlled trials. Cochrane Database Syst Rev 2007; issue 1.
14. Bryant J, Powell J. Payment to healthcare professionals for patient recruitment to trials: Systematic review. Br Med J 2005; 331 1377-1378.
15. Campbell M, Fitzpatrick R, Haines A et al. Framework for design and evaluation of complex interventions to improve health. Br Med J 2000; 321: 694-696.
16. Medical Research Council. Developing and evaluating complex interventions: New guidance. London: Medical Research Council, 2008.
17. Foy R, Parry J, Duggan A et al. How evidence based are recruitment strategies to randomized controlled trials in primary care? Experience from seven studies. Fam Pract 2003; 20: 83-92.
18. Pearl A, Wright S, Gamble G, Doughty R, Sharpe N. Randomised trials in general practice - a New Zealand experience in recruitment. N Z Med J 2003; 116: 1-7.
19. Fransen G, van Marrewijk C, Mujakovic S et al. Pragmatic trials in primary care: Methodological challenges and solutions demonstrated by the DIAMOND study. BMC Med Res Methodol 2007; 7 (16).
20. Bell-Syer S, Klaber-Moffett J. Recruiting patients to randomized trials in primary care: Principles and case study. Fam Pract 2000; 17 187-191.
21. Hetherton J, Matheson A, Robson M. Recruitment by GPs during consultations in a primary care randomized controlled trial comparing computerized psychological therapy with clinical psychology and routine GP care: Problems and possible solutions. Prim Health Care Res Dev 2004; 5: 5-10.
22. Mason V, Shaw A, Wiles N et al. GPs' experience of primary care mental health research: A qualitative study of the barriers to recruitment. Fam Pract 2007; 24: 518-525.
23. Stead M, Eadie D, Gordon D, Angus K. 'Hello, hello-it's English I speak!': A qualitative exploration of patients' understanding of the science of clinical trials. J Med Ethics 2005; 31: 664-669.
24. Donovan J, Mills N, Smith M et al. Improving design and conduct of randomised trials by embedding them in qualitative research: ProtecT (prostate testing for cancer and treatment) study. Br Med J 2002; 325: 766-770.
25. May C. A rational model for assessing and evaluating complex interventions in health care. BMC Health Serv Res 2006; 6: 86.
26. Hoddinott P, Britten J, Harrild K, Godden D. Recruitment issues when primary care population clusters are used in randomised controlled clinical trials: Climbing mountains or pushing boulders uphill? Contemp Clin Trials 2007; 28: 232-241.
27. Salmon P, Peters S, Rogers A et al. Peering through the barriers in GPs' explanations for declining to participate in research: The role of professional autonomy and the economy of time. Fam Pract 2007; 24: 269-275.
28. Hunt C, Shepherd L, Andrews G. Do doctors know best? Comments on a failed trial. Med J Aust 2001; 174: 144-146.
29. Darbyshire J. The UK Clinical Research Network - building a world-class infrastructure for clinical research. Rheumatology 2008; 47: 745.
30. Speedie S, Taweel A, Sim I, Arvanitis T, Delaney B, Peterson K. The primary care research object model (PCROM): A computable information model for practice-based primary care research. J Am Med Inform Assoc 2008; 15: 661-670.
31. UKCRN. UKCRC R&D Advisory Group to Connecting for Health (Report of Research Simulations). London: UKCRN, 2008.
32. Hummers-Pradiera E, Scheidt-Naveb C, Martin H, Heinemann S, Kochen M, Himmel W. Simply no time? Barriers to GPs' participation in primary health care research. Fam Pract 2008; 25: 105-112.
33. Carvel J. NHS Medical Research Plan Threatens Patient Privacy. The Guardian. www.guardian.co.uk/society/2008/nov/17/nhspatient- privacy-medical-research (accessed on 12 June 2009). 2008.
34. Buckley B. The need for wider public understanding of health care research. Prim Health Care Res Dev 2008; 9: 3-6.
35. Oliver S, Rees R, Clarke-Jones L et al.Amultidimensional conceptual framework for analysing public involvement in health services research. Health Expect 2007; 11: 72-84.
36. Dingwall R. An exercise in fatuity: Research governance and the emasculation of HSR. J Health Serv Res Policy 2006; 11: 193-194.
37. Delaney B. Engaging practitioners in research; time to change the values of practice rather than the way research is carried out? Fam Pract 2007; 24: 207-208.
38. Graffy J. Engaging family practitioners in research: Are we getting it right? Fam Pract 2008; 25: 69-70.
39. Graffy J, Grant J, Boase S et al. UK research staff perspectives on improving recruitment and retention to primary care research; nominal group exercise. Fam Pract 2009; 26: 48-55.
40. Junghans C, Feder G, Hemingway H, Timmis A, Jones M. Recruiting patients to medical research: Double blind randomised trial of "opt-in" versus "opt-out" strategies. Br Med J 2005; 331: 940.
41. Ward E, King M, Lloyd M, Bower P, Friedli K. Conducting randomized trials in general practice: Methodological and practical issues. Br J Gen Pract 1999; 49: 919-922.
42. Campbell M, Snowdon C, Francis C et al. Recruitment to randomised trials: Strategies for trial enrolment and particiTation study: the STEPS study. Health Technol Assess 2007; 11.
43. Prout H, Butler C, Kinnersley P, Robling M, Hood K, Tudor-Jones R. A qualitative evaluation of implementing a randomized controlled trial in general practice. Fam Pract 2003; 20: 675-681.
44. Fairhurst K, Dowrick C. Problems with recruitment in a randomised controlled trial of counselling in general practice: Causes and implications. J Health Serv Res Policy 1996; 1: 77-80.
45. Kuyvenhoven M, Dagnelie C, de Melker R. Recruitment of general practitioners and patients in a sore throat study. Br J Gen Pract 1997; 47: 126-127.
46. Mattson M, Curb D, McArdle R. Participation in a clinical trial: The patients' point of view. Control Clin Trials 1985; 6: 156-167.
47. Lawton J, Fox A, Fox C, Kinmonth A. Participating in the United Kingdom Prospective Diabetes Study (UKPDS): A qualitative study of patients' experiences. Br J Gen Pract 2003; 53: 394-398.
48. Bower P, King M, Nazareth I, Lampe F, Sibbald B. Patient preferences in randomised controlled trials: Conceptual framework and implications for research. Soc Sci Med 2005; 61: 685-695.
49. King M, Nazareth I, Lampe F et al. Impact of participant and physician intervention preferences on randomized trials: A systematic review. J Am Med Assoc 2005; 293: 1089-1099.