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Volumn 35, Issue 7, 2014, Pages 6195-6206

Focus on genetic and epigenetic events of colorectal cancer pathogenesis: Implications for molecular diagnosis

Author keywords

Biomolecular markers; Colorectal cancer pathogenesis; Epigenetic events; Genetic events

Indexed keywords

APC PROTEIN; BIOLOGICAL MARKER; HISTONE; K RAS PROTEIN; MICRORNA; PROTEIN P53;

EID: 84905005712     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-1845-9     Document Type: Review
Times cited : (98)

References (132)
  • 4
    • 0030932869 scopus 로고    scopus 로고
    • Cancer susceptibility genes. Gatekeepers and caretakers
    • Kinzler KW, Vogelstein B. Cancer susceptibility genes. Gatekeepers and caretakers. Nature. 1997;386(6627):761-3.
    • (1997) Nature , vol.386 , Issue.6627 , pp. 761-763
    • Kinzler, K.W.1    Vogelstein, B.2
  • 6
    • 77956103532 scopus 로고    scopus 로고
    • A review of the most promising biomarkers in colorectal cancer: One step closer to targeted therapy
    • Deschoolmeester V, Baay M, Specenier P, Lardon F, Vermorken JB. A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy. Oncologist. 2010;15(7):699-731.
    • (2010) Oncologist , vol.15 , Issue.7 , pp. 699-731
    • Deschoolmeester, V.1    Baay, M.2    Specenier, P.3    Lardon, F.4    Vermorken, J.B.5
  • 7
    • 77955064974 scopus 로고    scopus 로고
    • Genetic aspects of non-polypoid colorectal neoplasms
    • Kahng LS. Genetic aspects of non-polypoid colorectal neoplasms. Gastrointest Endosc Clin N Am. 2010;20(3):573-8.
    • (2010) Gastrointest Endosc Clin N Am , vol.20 , Issue.3 , pp. 573-578
    • Kahng, L.S.1
  • 8
    • 84866235428 scopus 로고    scopus 로고
    • Genetic and epigenetic events generate multiple pathways in colorectal cancer progression
    • Pancione M, Remo A, Colantuoni V. Genetic and epigenetic events generate multiple pathways in colorectal cancer progression. Pathol Res Int. 2012;2012:509348.
    • (2012) Pathol Res Int , vol.2012 , pp. 509348
    • Pancione, M.1    Remo, A.2    Colantuoni, V.3
  • 9
    • 79958173795 scopus 로고    scopus 로고
    • Colorectal cancer: Molecular features and clinical opportunities
    • Worthley DL, Leggett BA. Colorectal cancer: molecular features and clinical opportunities. Clin Biochem Rev. 2010;31(2):31-8.
    • (2010) Clin Biochem Rev , vol.31 , Issue.2 , pp. 31-38
    • Worthley, D.L.1    Leggett, B.A.2
  • 10
    • 80052768206 scopus 로고    scopus 로고
    • Pathways of carcinogenesis are reflected in patterns of polyp pathology in patients screened for colorectal cancer
    • Costedio M, Church J. Pathways of carcinogenesis are reflected in patterns of polyp pathology in patients screened for colorectal cancer. Dis Colon Rectum. 2011;54(10):1224-8.
    • (2011) Dis Colon Rectum , vol.54 , Issue.10 , pp. 1224-1228
    • Costedio, M.1    Church, J.2
  • 11
    • 79751489596 scopus 로고    scopus 로고
    • Molecular genetics of colorectal cancer
    • Fearon ER. Molecular genetics of colorectal cancer. Annu Rev Pathol. 2011;6:479-507.
    • (2011) Annu Rev Pathol , vol.6 , pp. 479-507
    • Fearon, E.R.1
  • 12
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 1990;61(5):759-67.
    • (1990) Cell , vol.61 , Issue.5 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 13
    • 77951627056 scopus 로고    scopus 로고
    • The chromosomal instability pathway in colon cancer
    • Pino MS, Chung DC. The chromosomal instability pathway in colon cancer. Gastroenterology. 2010;138(6):2059-72.
    • (2010) Gastroenterology , vol.138 , Issue.6 , pp. 2059-2072
    • Pino, M.S.1    Chung, D.C.2
  • 14
    • 42149114501 scopus 로고    scopus 로고
    • Crosstalk between tumor cells and microenvironment via Wnt pathway in colorectal cancer dissemination
    • DOI 10.3748/wjg.14.1823
    • Huang D, Du X. Crosstalk between tumor cells and microenvironment via Wnt pathway in colorectal cancer dissemination. World J Gastroenterol. 2008;14(12):1823-7. (Pubitemid 351523810)
    • (2008) World Journal of Gastroenterology , vol.14 , Issue.12 , pp. 1823-1827
    • Huang, D.1    Du, X.2
  • 15
    • 33947309748 scopus 로고    scopus 로고
    • Minimally invasive biomarkers for detection and staging of colorectal cancer
    • DOI 10.1016/j.canlet.2006.12.021, PII S0304383506006951, Cancer Biomarkers Special Issue
    • Booth RA.Minimally invasive biomarkers for detection and staging of colorectal cancer. Cancer Lett. 2007;249(1):87-96. (Pubitemid 46437280)
    • (2007) Cancer Letters , vol.249 , Issue.1 , pp. 87-96
    • Booth, R.A.1
  • 16
    • 67650489071 scopus 로고    scopus 로고
    • Clinical biomarkers in oncology: Focus on colorectal cancer
    • De Roock W, Biesmans B, De Schutter J, Tejpar S. Clinical biomarkers in oncology: focus on colorectal cancer. Mol Diag Ther. 2009;13(2):103-14.
    • (2009) Mol Diag Ther , vol.13 , Issue.2 , pp. 103-114
    • De Roock, W.1    Biesmans, B.2    De Schutter, J.3    Tejpar, S.4
  • 17
    • 77952956887 scopus 로고    scopus 로고
    • Oncogenic mutations as predictive factors in colorectal cancer
    • Lievre A, Blons H, Laurent-Puig P. Oncogenic mutations as predictive factors in colorectal cancer. Oncogene. 2010;29(21):3033-43.
    • (2010) Oncogene , vol.29 , Issue.21 , pp. 3033-3043
    • Lievre, A.1    Blons, H.2    Laurent-Puig, P.3
  • 20
    • 77956103532 scopus 로고    scopus 로고
    • A review of themost promising biomarkers in colorectal cancer: One step closer to targeted therapy
    • Deschoolmeester V, Baay M, Specenier P, Lardon F, Vermorken JB. A review of themost promising biomarkers in colorectal cancer: one step closer to targeted therapy. Oncologist. 2010;15(7):699-731.
    • (2010) Oncologist , vol.15 , Issue.7 , pp. 699-731
    • Deschoolmeester, V.1    Baay, M.2    Specenier, P.3    Lardon, F.4    Vermorken, J.B.5
  • 22
    • 84866235163 scopus 로고    scopus 로고
    • Molecular events in primary and metastatic colorectal carcinoma: A review
    • Kanthan R, Senger AL, Kanthan C. Molecular events in primary and metastatic colorectal carcinoma: a review. Pathol Res Int. 2012;2012:597497.
    • (2012) Pathol Res Int , vol.2012 , pp. 597497
    • Kanthan, R.1    Senger, A.L.2    Kanthan, C.3
  • 23
    • 72449176846 scopus 로고    scopus 로고
    • Molecular basis of colorectal cancer
    • Markowitz SD, Bertagnolli MM. Molecular basis of colorectal cancer. N Engl J Med. 2009;361(25):2404-60.
    • (2009) N Engl J Med , vol.361 , Issue.25 , pp. 2404-2460
    • Markowitz, S.D.1    Bertagnolli, M.M.2
  • 25
    • 37149041833 scopus 로고    scopus 로고
    • Molecular classification and correlates in colorectal cancer
    • DOI 10.2353/jmoldx.2008.070082
    • Ogino S, Goel A. Molecular classification and correlates in colorectal cancer. J Mol Diagn. 2008;10(1):13-27. (Pubitemid 351184831)
    • (2008) Journal of Molecular Diagnostics , vol.10 , Issue.1 , pp. 13-27
    • Ogino, S.1    Goel, A.2
  • 26
    • 33845608798 scopus 로고    scopus 로고
    • Classification of colorectal cancer based on correlation of clinical, morphological and molecular features
    • DOI 10.1111/j.1365-2559.2006.02549.x
    • Jass JR. Classification of colorectal cancer based on correlation of clinical, morphological and molecular features. Histopathology. 2007;50(1):113-30. (Pubitemid 44953403)
    • (2007) Histopathology , vol.50 , Issue.1 , pp. 113-130
    • Jass, J.R.1
  • 28
    • 40849139208 scopus 로고    scopus 로고
    • Molecular origins of cancer: Epigenetics in cancer
    • Esteller M. Molecular origins of cancer: epigenetics in cancer. N Engl J Med. 2008;358(11):1148-096.
    • (2008) N Engl J Med , vol.358 , Issue.11 , pp. 1148-2096
    • Esteller, M.1
  • 29
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 30
    • 53049087109 scopus 로고    scopus 로고
    • Genomic and epigenetic instability in colorectal cancer pathogenesis
    • Grady WM, Carethers JM. Genomic and epigenetic instability in colorectal cancer pathogenesis. Gastroenterology. 2008;135(4):1079-99.
    • (2008) Gastroenterology , vol.135 , Issue.4 , pp. 1079-1099
    • Grady, W.M.1    Carethers, J.M.2
  • 31
    • 77449130761 scopus 로고    scopus 로고
    • Microsatellite instability in colorectal cancer
    • Boland CR, Goel A. Microsatellite instability in colorectal cancer. Gastroenterology. 2010;138(6):2073-87.
    • (2010) Gastroenterology , vol.138 , Issue.6 , pp. 2073-2087
    • Boland, C.R.1    Goel, A.2
  • 32
    • 78649766938 scopus 로고    scopus 로고
    • Microsatellite instability in colorectal cancer
    • Iacopetta B, Grieu F, Amanuel B. Microsatellite instability in colorectal cancer. Asia-Pac J Clin Oncol. 2010;6(4):260-9.
    • (2010) Asia-Pac J Clin Oncol , vol.6 , Issue.4 , pp. 260-269
    • Iacopetta, B.1    Grieu, F.2    Amanuel, B.3
  • 33
    • 77954720070 scopus 로고    scopus 로고
    • Clinical relevance of microsatellite instability in colorectal cancer
    • De la Chapelle A, Hampel H. Clinical relevance of microsatellite instability in colorectal cancer. J Clin Oncol. 2010;28(20):3380-7.
    • (2010) J Clin Oncol , vol.28 , Issue.20 , pp. 3380-3387
    • De La Chapelle, A.1    Hampel, H.2
  • 34
    • 0038002289 scopus 로고    scopus 로고
    • Microsatellite instability
    • De la Chapelle A. Microsatellite instability. N Engl J Med. 2003;349(3):209-2010.
    • (2003) N Engl J Med , vol.349 , Issue.3 , pp. 209-2010
    • De La Chapelle, A.1
  • 36
    • 84872818172 scopus 로고    scopus 로고
    • Microsatellite instability in metastatic colorectal cancer: A review of pathology, response to chemotherapy and clinical outcome
    • Yim KL. Microsatellite instability in metastatic colorectal cancer: a review of pathology, response to chemotherapy and clinical outcome. Med Oncol. 2012;29(3):1796-801.
    • (2012) Med Oncol , vol.29 , Issue.3 , pp. 1796-1801
    • Yim, K.L.1
  • 37
    • 53049087109 scopus 로고    scopus 로고
    • Genomic and epigenetic instability in colorectal cancer
    • Grady WM, Carethers JM. Genomic and epigenetic instability in colorectal cancer. Gastroenterology. 2008;135(4):1079-99.
    • (2008) Gastroenterology , vol.135 , Issue.4 , pp. 1079-1099
    • Grady, W.M.1    Carethers, J.M.2
  • 40
    • 71049136170 scopus 로고    scopus 로고
    • MicroRNAs in colorectal cancer: Translation of molecular biology into clinical application
    • Slaby O, Svoboda M, Michalek J, Vyzula R. MicroRNAs in colorectal cancer: translation of molecular biology into clinical application. Mol Cancer. 2009;8:102.
    • (2009) Mol Cancer , vol.8 , pp. 102
    • Slaby, O.1    Svoboda, M.2    Michalek, J.3    Vyzula, R.4
  • 41
    • 74249097210 scopus 로고    scopus 로고
    • Recent insights into the pathogenesis of colorectal cancer
    • Goel A, Boland CR. Recent insights into the pathogenesis of colorectal cancer. Curr Opin Gastroenterol. 2010;26(1):47-52.
    • (2010) Curr Opin Gastroenterol , vol.26 , Issue.1 , pp. 47-52
    • Goel, A.1    Boland, C.R.2
  • 43
    • 62549134412 scopus 로고    scopus 로고
    • MicroRNA and colorectal cancer
    • Yang L, Belaguli N, Berger DH. MicroRNA and colorectal cancer. World J Surg. 2009;33(4):638-46.
    • (2009) World J Surg , vol.33 , Issue.4 , pp. 638-646
    • Yang, L.1    Belaguli, N.2    Berger, D.H.3
  • 44
    • 77957970301 scopus 로고    scopus 로고
    • Epigenetic modifications and human disease
    • Portela A, Esteller M. Epigenetic modifications and human disease. Nat Biotechnol. 2010;28(10):1057-68.
    • (2010) Nat Biotechnol , vol.28 , Issue.10 , pp. 1057-1068
    • Portela, A.1    Esteller, M.2
  • 45
    • 33846008439 scopus 로고    scopus 로고
    • Colorectal cancer: A model for epigenetic tumorigenesis
    • DOI 10.1136/gut.2005.088799
    • Wong JJL, Hawkins NJ, Ward RL. Colorectal cancer: a model for epigenetic tumorigenesis. Gut. 2007;56(1):140-8. (Pubitemid 46044900)
    • (2007) Gut , vol.56 , Issue.1 , pp. 140-148
    • Wong, J.J.L.1    Hawkins, N.J.2    Ward, R.L.3
  • 47
    • 44449100509 scopus 로고    scopus 로고
    • Epigenetic changes (aberrant DNA methylation) in colorectal neoplasia
    • Kim YS, Deng G. Epigenetic changes (aberrant DNA methylation) in colorectal neoplasia. Gut Liver. 2007;1(1):1-11.
    • (2007) Gut Liver , vol.1 , Issue.1 , pp. 1-11
    • Kim, Y.S.1    Deng, G.2
  • 51
    • 84878217671 scopus 로고    scopus 로고
    • Gene expression: Colorectal cancer classification
    • Burgess DJ. Gene expression: colorectal cancer classification. Nat Rev Cancer. 2013;13(6):380-1.
    • (2013) Nat Rev Cancer , vol.13 , Issue.6 , pp. 380-381
    • Burgess, D.J.1
  • 52
    • 84877619075 scopus 로고    scopus 로고
    • A colorectal cancer classification system that associates cellular phenotype and responses to therapy
    • Sadanandam A, Lyssiotis CA, Homicsko H, et al. A colorectal cancer classification system that associates cellular phenotype and responses to therapy. Nat Med. 2013;19(5):619-25.
    • (2013) Nat Med , vol.19 , Issue.5 , pp. 619-625
    • Sadanandam, A.1    Lyssiotis, C.A.2    Homicsko, H.3
  • 53
    • 84877600884 scopus 로고    scopus 로고
    • Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions
    • De Sosa E, Melo F, Wang X, Jansen M, et al. Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions. Nat Med. 2013;19(5):614-8.
    • (2013) Nat Med , vol.19 , Issue.5 , pp. 614-618
    • De Sosa, E.1    Melo, F.2    Wang, X.3    Jansen, M.4
  • 54
    • 77949928737 scopus 로고    scopus 로고
    • Lifestyle factors and microsatellite instability in colorectal cancer: The evolving field of molecular pathological epidemiology
    • Ogino S, Stampfer M. Lifestyle factors and microsatellite instability in colorectal cancer: the evolving field of molecular pathological epidemiology. J Natl Cancer Inst. 2010;102(6):365-7.
    • (2010) J Natl Cancer Inst , vol.102 , Issue.6 , pp. 365-367
    • Ogino, S.1    Stampfer, M.2
  • 55
    • 79851511414 scopus 로고    scopus 로고
    • Molecular Pathologic epidemiology of colorectal neoplasia: An emerging transdisciplinary and interdisciplinary field
    • Ogino S, Chan AT, Fuchs S, Giovannucci E. Molecular Pathologic epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field. Gut. 2011;60(3):397-411.
    • (2011) Gut , vol.60 , Issue.3 , pp. 397-411
    • Ogino, S.1    Chan, A.T.2    Fuchs, S.3    Giovannucci, E.4
  • 56
    • 33749069927 scopus 로고    scopus 로고
    • CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: Possible associations with male sex and KRAS mutations
    • DOI 10.2353/jmoldx.2006.060082
    • Ogino S, Kawasaki T, Kirkner GJ, Loda M, Fuchs CS. CpG island methylator phenotype-low (CIMP-Low) in colorectal cancer: possible associations withmale sex and KRASmutations. JMol Diagn. 2006;8(5):582-8. (Pubitemid 44774157)
    • (2006) Journal of Molecular Diagnostics , vol.8 , Issue.5 , pp. 582-588
    • Ogino, S.1    Kawasaki, T.2    Kirkner, G.J.3    Loda, M.4    Fuchs, C.S.5
  • 59
    • 0042025123 scopus 로고    scopus 로고
    • Methylation and prognosis: Of molecular clocks and hypermethylator phenotypes
    • Issa JP. Methylation and prognosis: of molecular clocks and hypermethylator phenotypes. Clin Cancer Res. 2003;9(8):2879-81.
    • (2003) Clin Cancer Res , vol.9 , Issue.8 , pp. 2879-2881
    • Issa, J.P.1
  • 60
    • 35948981194 scopus 로고    scopus 로고
    • Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy
    • Shen L, Catalano PJ, Benson AB, O'Dwyer P, Hamilton SR, Issa JP. Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy. Cl in Cancer Res. 2007;13(20):6093 -8.
    • (2007) Cl in Cancer Res , vol.13 , Issue.20 , pp. 6093-6098
    • Shen, L.1    Catalano, P.J.2    Benson, A.B.3    O'Dwyer, P.4    Hamilton, S.R.5    Issa, J.P.6
  • 63
    • 78649985198 scopus 로고    scopus 로고
    • Update on the serrated pathway to colorectal carcinoma
    • Snover DC. Update on the serrated pathway to colorectal carcinoma. Hum Pathol. 2011;42:1-10.
    • (2011) Hum Pathol , vol.42 , pp. 1-10
    • Snover, D.C.1
  • 65
    • 77956623471 scopus 로고    scopus 로고
    • Diet and cancer prevention: Contributions from the European Prospective Investigation into Cancer and Nutrition (EPIC) study
    • Gonzalez CA, Riboli E. Diet and cancer prevention: contributions from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Eur J Cancer. 2010;46:2555-62.
    • (2010) Eur J Cancer , vol.46 , pp. 2555-2562
    • Gonzalez, C.A.1    Riboli, E.2
  • 66
    • 78049482726 scopus 로고    scopus 로고
    • The presence of large serrated polyps increases risk for colorectal cancer
    • Hiraoka S, Kato J, Fujiki S, Kaji E, Morikami T, Nawa T, et al. The presence of large serrated polyps increases risk for colorectal cancer. Gastroenterology. 2010;139:1503-10.
    • (2010) Gastroenterology , vol.139 , pp. 1503-1510
    • Hiraoka, S.1    Kato, J.2    Fujiki, S.3    Kaji, E.4    Morikami, T.5    Nawa, T.6
  • 67
    • 77957108842 scopus 로고    scopus 로고
    • Male sex and smoking have a larger impact on the prevalence of colorectal neoplasia than family history of colorectal cancer
    • Hoffmeister M, Schmitz S, Karmrodt E, Stegmaier C, Haug U, Arndt V, et al. Male sex and smoking have a larger impact on the prevalence of colorectal neoplasia than family history of colorectal cancer. Clin Gastroenterol Hepatol. 2010;8:870-6.
    • (2010) Clin Gastroenterol Hepatol , vol.8 , pp. 870-876
    • Hoffmeister, M.1    Schmitz, S.2    Karmrodt, E.3    Stegmaier, C.4    Haug, U.5    Arndt, V.6
  • 68
    • 78149410344 scopus 로고    scopus 로고
    • The comparison of the clinical manifestations and risk factors of colorectal cancer and adenomas: Results from a colonoscopy-based study in southern Chinese
    • Huang L, Wang X, Gong W, Huang Y, Jiang B. The comparison of the clinical manifestations and risk factors of colorectal cancer and adenomas: results from a colonoscopy-based study in southern Chinese. Int J Color Dis. 2010;25:1343-51.
    • (2010) Int J Color Dis , vol.25 , pp. 1343-1351
    • Huang, L.1    Wang, X.2    Gong, W.3    Huang, Y.4    Jiang, B.5
  • 69
    • 33750617498 scopus 로고    scopus 로고
    • Meat consumption and risk of colorectal cancer: A meta-analysis of prospective studies
    • DOI 10.1002/ijc.22170
    • Larsson SC, Wolk A. Meat consumption and risk of colorectal cancer: a meta-analysis of prospective studies. Int J Cancer. 2006;119:2657-64. (Pubitemid 44691322)
    • (2006) International Journal of Cancer , vol.119 , Issue.11 , pp. 2657-2664
    • Larsson, S.C.1    Wolk, A.2
  • 70
  • 71
    • 77949950879 scopus 로고    scopus 로고
    • Dietary folate, alcohol, and B vitamins in relation to line-1 hypomethylation in colon cancer
    • Schernhammer ES, Giovannucci E, Kawasaki T, Rosner R, Fuchs CS, Ogino S. Dietary folate, alcohol, and B vitamins in relation to line-1 hypomethylation in colon cancer. Gut. 2010;59:794-9.
    • (2010) Gut , vol.59 , pp. 794-799
    • Schernhammer, E.S.1    Giovannucci, E.2    Kawasaki, T.3    Rosner, R.4    Fuchs, C.S.5    Ogino, S.6
  • 78
    • 77949953247 scopus 로고    scopus 로고
    • Case-control study of overweight, obesity, and colorectal cancer risk, overall and by tumor microsatellite instability status
    • Campbell PT, Jacobs ET, Ulrich CM, Figueiredo JC, Poynter JN, McLaughlin JR, et al. Case-control study of overweight, obesity, and colorectal cancer risk, overall and by tumor microsatellite instability status. J Natl Cancer Inst. 2010;17:391-400.
    • (2010) J Natl Cancer Inst , vol.17 , pp. 391-400
    • Campbell, P.T.1    Jacobs, E.T.2    Ulrich, C.M.3    Figueiredo, J.C.4    Poynter, J.N.5    McLaughlin, J.R.6
  • 79
    • 84858134589 scopus 로고    scopus 로고
    • Bodymass index and risk of colorectal cancer according to fatty acid synthase expression in the nurses' health study
    • Kuchiba A, Morikawa T, Yamauchi M, Imamura Y, Liao X, Chan AT, et al. Bodymass index and risk of colorectal cancer according to fatty acid synthase expression in the nurses' health study. J Natl Cancer Inst. 2012;104:415-20.
    • (2012) J Natl Cancer Inst , vol.104 , pp. 415-420
    • Kuchiba, A.1    Morikawa, T.2    Yamauchi, M.3    Imamura, Y.4    Liao, X.5    Chan, A.T.6
  • 80
    • 84874927068 scopus 로고    scopus 로고
    • Prospective analysis of body mass index, physical activity, and colorectal cancer risk associated with b-catenin (CTNNB1) status
    • Morikawa T, Kuchiba A, Lochhead P, Nishihara R, Yamauchi M, Imamura Y, et al. Prospective analysis of body mass index, physical activity, and colorectal cancer risk associated with b-catenin (CTNNB1) status. Cancer Res. 2013;73(5):1600-10.
    • (2013) Cancer Res , vol.73 , Issue.5 , pp. 1600-1610
    • Morikawa, T.1    Kuchiba, A.2    Lochhead, P.3    Nishihara, R.4    Yamauchi, M.5    Imamura, Y.6
  • 83
    • 84876484863 scopus 로고    scopus 로고
    • A prospective study of duration of smoking cessation and colorectal cancer risk by epigenetics-related tumor classification
    • Nishihara R, Morikawa T, Kuchiba A, Lochhead P, Yamauchi M, Liao X, et al. A prospective study of duration of smoking cessation and colorectal cancer risk by epigenetics-related tumor classification. Am J Epidemiol. 2013;1(178):84-100.
    • (2013) Am J Epidemiol , vol.1 , Issue.178 , pp. 84-100
    • Nishihara, R.1    Morikawa, T.2    Kuchiba, A.3    Lochhead, P.4    Yamauchi, M.5    Liao, X.6
  • 84
    • 84879395305 scopus 로고    scopus 로고
    • Aspirin use and risk of colorectal cancer according to BRAF mutation status
    • Nishihara R, Lochhead P, Kuchiba A, Jung S, YamauchiM, Liao X, et al. Aspirin use and risk of colorectal cancer according to BRAF mutation status. JAMA. 2013;309(24):2563-71.
    • (2013) JAMA , vol.309 , Issue.24 , pp. 2563-2571
    • Nishihara, R.1    Lochhead, P.2    Kuchiba, A.3    Jung, S.4    Yamauchi, M.5    Liao, X.6
  • 85
    • 34249673868 scopus 로고    scopus 로고
    • Aspirin and the risk of colorectal cancer in relation to the expression of COX-2
    • DOI 10.1056/NEJMoa067208
    • Chan AT, Ogino S, Fuchs CS. Aspirin and the risk of colorectal cancer in relation to the expression of COX-2. N Engl J Med. 2007;356(21):2131-42. (Pubitemid 47010839)
    • (2007) New England Journal of Medicine , vol.356 , Issue.21 , pp. 2131-2142
    • Chan, A.T.1    Ogino, S.2    Fuchs, C.S.3
  • 86
  • 87
    • 81855166109 scopus 로고    scopus 로고
    • Tumor-associated macrophages (tam) and inflammation in colorectal cancer
    • Erreni M, Mantovani A, Allavena P. Tumor-associated macrophages (tam) and inflammation in colorectal cancer. Cancer Microenviron. 2011;4:141-54.
    • (2011) Cancer Microenviron , vol.4 , pp. 141-154
    • Erreni, M.1    Mantovani, A.2    Allavena, P.3
  • 88
    • 8144228952 scopus 로고    scopus 로고
    • Friends or foes - Bipolar effects of the tumour stroma in cancer
    • DOI 10.1038/nrc1477
    • Mueller MM, Fusenig NE. Friends or foes-Bipolar effects of the tumour stroma in cancer. Nat Rev Cancer. 2004;4:839-49. (Pubitemid 39472951)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.11 , pp. 839-849
    • Mueller, M.M.1    Fusenig, N.E.2
  • 89
    • 0035080617 scopus 로고    scopus 로고
    • The risk of colorectal cancer in ulcerative colitis: A meta-analysis
    • DOI 10.1136/gut.48.4.526
    • Eaden JA, Abrams KR, Mayberry JF. The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut. 2001;48:526-35. (Pubitemid 32234798)
    • (2001) Gut , vol.48 , Issue.4 , pp. 526-535
    • Eaden, J.A.1    Abrams, K.R.2    Mayberry, J.F.3
  • 90
  • 91
    • 34548178346 scopus 로고    scopus 로고
    • Genetic polymorphisms in one-carbon metabolism: Associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet
    • DOI 10.1093/carcin/bgm089
    • Curtin K, Slattery ML, Ulrich CM, Bigler J, Levin TR, Wolff RK, et al. Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet. Carcinogenesis. 2007;28(8):1672-9. (Pubitemid 47303944)
    • (2007) Carcinogenesis , vol.28 , Issue.8 , pp. 1672-1679
    • Curtin, K.1    Slattery, M.L.2    Ulrich, C.M.3    Bigler, J.4    Levin, T.R.5    Wolff, R.K.6    Albertsen, H.7    Potter, J.D.8    Samowitz, W.S.9
  • 94
    • 58349100488 scopus 로고    scopus 로고
    • Methionine synthase A2756G polymorphism interacts with alcohol and folate intake to influence the risk of colorectal adenoma
    • Yamaji T, Iwasaki M, Sasazuki S, Sakamoto H, Yoshida T, Tsugane S. Methionine synthase A2756G polymorphism interacts with alcohol and folate intake to influence the risk of colorectal adenoma. Cancer Epidemiol Biomarkers Prev. 2009;18(1):267-74.
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , Issue.1 , pp. 267-274
    • Yamaji, T.1    Iwasaki, M.2    Sasazuki, S.3    Sakamoto, H.4    Yoshida, T.5    Tsugane, S.6
  • 95
    • 66149137224 scopus 로고    scopus 로고
    • The MTHFR C677T and ΔDNMT3B C-149 T polymorphisms confer different risks for right- and left-sided colorectal cancer
    • Iacopetta B, Heyworth J, Girschik J, Grieu F, Clayforth C, Fritschi L. The MTHFR C677T and ΔDNMT3B C-149 T polymorphisms confer different risks for right- and left-sided colorectal cancer. Int J Cancer. 2009;125(1):84-90.
    • (2009) Int J Cancer , vol.125 , Issue.1 , pp. 84-90
    • Iacopetta, B.1    Heyworth, J.2    Girschik, J.3    Grieu, F.4    Clayforth, C.5    Fritschi, L.6
  • 97
    • 34347381073 scopus 로고    scopus 로고
    • Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline
    • DOI 10.1080/15216540701468954, PII 779717256
    • Zeisel SH. Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline. IUBMB Life. 2007;59(6):380-7. (Pubitemid 47027115)
    • (2007) IUBMB Life , vol.59 , Issue.6 , pp. 380-387
    • Zeisel, S.H.1
  • 99
    • 74749087005 scopus 로고    scopus 로고
    • Low folate transport across intestinal basolateral surface is associated with down-regulation of reduced folate carrier in in vivo model of folate malabsorption
    • Hamid A, Kiran M, Rana S, Kaur J. Low folate transport across intestinal basolateral surface is associated with down-regulation of reduced folate carrier in in vivo model of folate malabsorption. IUBMB Life. 2009;61(3):236-43.
    • (2009) IUBMB Life , vol.61 , Issue.3 , pp. 236-243
    • Hamid, A.1    Kiran, M.2    Rana, S.3    Kaur, J.4
  • 100
    • 77957576132 scopus 로고    scopus 로고
    • Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas
    • Paun BC, Kukuruga D, Jin Z, Mori Y, Cheng Y, Duncan M, et al. Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas. Cancer. 2010;116(19):4495-501.
    • (2010) Cancer , vol.116 , Issue.19 , pp. 4495-4501
    • Paun, B.C.1    Kukuruga, D.2    Jin, Z.3    Mori, Y.4    Cheng, Y.5    Duncan, M.6
  • 103
    • 67650924286 scopus 로고    scopus 로고
    • Review of the Lynch syndrome: History, molecular genetics, screening, differential diagnosis, and medicolegal ramifications
    • Lynch HT, Lynch PM, Lanspa SJ, Snyder CL, Lynch JF, Boland CR. Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications. Clin Genet. 2009;76(1):1-18.
    • (2009) Clin Genet , vol.76 , Issue.1 , pp. 1-18
    • Lynch, H.T.1    Lynch, P.M.2    Lanspa, S.J.3    Snyder, C.L.4    Lynch, J.F.5    Boland, C.R.6
  • 107
    • 74549152528 scopus 로고    scopus 로고
    • Aspirin prevents cancer in Lynch syndrome
    • Burn J. Aspirin prevents cancer in Lynch syndrome. Eur J Cancer. 2009;7:320-1.
    • (2009) Eur J Cancer , vol.7 , pp. 320-321
    • Burn, J.1
  • 109
    • 77949368522 scopus 로고    scopus 로고
    • Gardner syndrome: Skin manifestations, differential diagnosis and management
    • Juhn E, Khachemoune A. Gardner syndrome: skin manifestations, differential diagnosis and management. Am J Clin Dermatol. 2010;11(2):117-22.
    • (2010) Am J Clin Dermatol , vol.11 , Issue.2 , pp. 117-122
    • Juhn, E.1    Khachemoune, A.2
  • 110
    • 33846074011 scopus 로고    scopus 로고
    • Correlations between mutation site in APC and phenotype of familial adenomatous polyposis (FAP): A review of the literature
    • DOI 10.1016/j.critrevonc.2006.07.004, PII S1040842806001314
    • Nieuwenhuis MH, Vasen HF. Correlations between mutation site in APC and phenotype of familial adenomatous polyposis (FAP): a review of the literature. Crit Rev Oncol Hematol. 2007;61:153-61. (Pubitemid 46073779)
    • (2007) Critical Reviews in Oncology/Hematology , vol.61 , Issue.2 , pp. 153-161
    • Nieuwenhuis, M.H.1    Vasen, H.F.A.2
  • 111
    • 33749070180 scopus 로고    scopus 로고
    • Peutz-Jeghers syndrome: Clinicopathology and molecular alterations
    • DOI 10.1007/s00018-006-6080-0
    • McGarrity TJ, Amos C. Peutz-Jeghers syndrome: clinicopathology and molecular alterations. Cell Mol Life Sci. 2006;63(18):2135-44. (Pubitemid 44465687)
    • (2006) Cellular and Molecular Life Sciences , vol.63 , Issue.18 , pp. 2135-2144
    • McGarrity, T.J.1    Amos, C.2
  • 112
    • 47849085326 scopus 로고    scopus 로고
    • Hamartomatous Polyposis Syndromes
    • DOI 10.1016/j.suc.2008.05.002, PII S0039610908000698
    • Calva D, Howe JR. Hamartomatous polyposis syndromes. Surg Clin N Am. 2008;88(4):779-817. (Pubitemid 352040755)
    • (2008) Surgical Clinics of North America , vol.88 , Issue.4 , pp. 779-817
    • Calva, D.1    Howe, J.R.2
  • 113
    • 84889568314 scopus 로고    scopus 로고
    • Molecular classification of colorectal carcinomas: The genotype to phenotype relation
    • Kaemmerer E, Klaus C, Jeon MK, Gassler N. Molecular classification of colorectal carcinomas: the genotype to phenotype relation. World J Gastroenterol. 2013;19(45):8163-7.
    • (2013) World J Gastroenterol , vol.19 , Issue.45 , pp. 8163-8167
    • Kaemmerer, E.1    Klaus, C.2    Jeon, M.K.3    Gassler, N.4
  • 114
    • 77951647898 scopus 로고    scopus 로고
    • Role of the serrated pathway in colorectal cancer pathogenesis
    • Leggett B, Whitehall V. Role of the serrated pathway in colorectal cancer pathogenesis. Gastroenterology. 2010;138:2088-100.
    • (2010) Gastroenterology , vol.138 , pp. 2088-2100
    • Leggett, B.1    Whitehall, V.2
  • 115
    • 39649118620 scopus 로고    scopus 로고
    • Sporadic and Syndromic Hyperplastic Polyps and Serrated Adenomas of the Colon: Classification, Molecular Genetics, Natural History, and Clinical Management
    • DOI 10.1016/j.gtc.2007.12.014, PII S0889855307001380
    • East JE, Saunders BP, Jass JR. Sporadic and syndromic hyperplastic polyps and serrated adenomas of the colon: classification, molecular genetics, natural history, and clinical management. Gastroenterol Clin N Am. 2008;37:25-46. (Pubitemid 351289032)
    • (2008) Gastroenterology Clinics of North America , vol.37 , Issue.1 , pp. 25-46
    • East, J.E.1    Saunders, B.P.2    Jass, J.R.3
  • 116
    • 84892991589 scopus 로고    scopus 로고
    • Cancer stem cells in colorectal cancer from pathogenesis to therapy: Controversies and perspectives
    • Fanali C, Lucchetti D, Farina M, Corbi M, Cufino V, Cittadini A, et al. Cancer stem cells in colorectal cancer from pathogenesis to therapy: controversies and perspectives. World J Gastroenterol. 2014;20(4):923-42.
    • (2014) World J Gastroenterol , vol.20 , Issue.4 , pp. 923-942
    • Fanali, C.1    Lucchetti, D.2    Farina, M.3    Corbi, M.4    Cufino, V.5    Cittadini, A.6
  • 118
    • 11144285448 scopus 로고    scopus 로고
    • Stool screening for colorectal cancer: Molecular approaches
    • DOI 10.1053/j.gastro.2004.10.041, PII S0016508504019912
    • Osborn NK, Ahlquist DA. Stool screening for colorectal cancer: molecular approaches. Gastroenterology. 2005;128(1):192-206. (Pubitemid 40039970)
    • (2005) Gastroenterology , vol.128 , Issue.1 , pp. 192-206
    • Osborn, N.K.1    Ahlquist, D.A.2
  • 120
    • 23244434445 scopus 로고    scopus 로고
    • Fecal DNA biomarkers for the detection of colorectal neoplasia: Attractive, but is it feasible?
    • DOI 10.1093/jnci/dji244
    • Brenner DE, Rennert G. Fecal DNA biomarkers for the detection of colorectal neoplasia: attractive, but is it feasible? J Natl Cancer Inst. 2005;97(15):1107-9. (Pubitemid 41511203)
    • (2005) Journal of the National Cancer Institute , vol.97 , Issue.15 , pp. 1107-1109
    • Brenner, D.E.1    Rennert, G.2
  • 122
    • 77349107376 scopus 로고    scopus 로고
    • DNA methylation markers in colorectal cancer
    • Kim MS, Lee J, Sidransky D. DNA methylation markers in colorectal cancer. Cancer Metastasis Rev. 2010;29(1):181-206.
    • (2010) Cancer Metastasis Rev , vol.29 , Issue.1 , pp. 181-206
    • Kim, M.S.1    Lee, J.2    Sidransky, D.3
  • 123
    • 79952191728 scopus 로고    scopus 로고
    • Methylation of the 3p22 region encompassing MLH1 is representative of the CpG island methylator phenotype in colorectal cancer
    • Wong JJL, Hawkins NJ, Ward RL, Hitchins MP. Methylation of the 3p22 region encompassing MLH1 is representative of the CpG island methylator phenotype in colorectal cancer. Mod Pathol. 2011;24(3):396-411.
    • (2011) Mod Pathol , vol.24 , Issue.3 , pp. 396-411
    • Wong, J.J.L.1    Hawkins, N.J.2    Ward, R.L.3    Hitchins, M.P.4
  • 124
    • 0035815919 scopus 로고    scopus 로고
    • Detecting colorectal cancer in stool with the use of multiple genetic targets
    • Dong SM, Traverso G, Johnson C, et al. Detecting colorectal cancer in stool with the use of multiple genetic targets. J Natl Cancer Inst. 2001;93:851-65.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 851-865
    • Dong, S.M.1    Traverso, G.2    Johnson, C.3
  • 125
    • 0034322371 scopus 로고    scopus 로고
    • Colorectal cancer screeningby detection of altered human DNA in stool; feasibility of a mutitarget assay panel
    • Alquist DA, Skoletsky JE, Boynton KA, et al. Colorectal cancer screening]by detection of altered human DNA in stool; feasibility of a mutitarget assay panel. Gastroenterology. 2000;119:1219-27.
    • (2000) Gastroenterology , vol.119 , pp. 1219-1227
    • Alquist, D.A.1    Skoletsky, J.E.2    Boynton, K.A.3
  • 127
    • 84888356699 scopus 로고    scopus 로고
    • Aberrant methylation of NPY, PENK, and WIF1 as a promising marker for blood-based diagnosis of colorectal cancer
    • Roperch JP, Incitti R, Forbin F, et al. Aberrant methylation of NPY, PENK, and WIF1 as a promising marker for blood-based diagnosis of colorectal cancer. BMC Cancer. 2013;13:566.
    • (2013) BMC Cancer , vol.13 , pp. 566
    • Roperch, J.P.1    Incitti, R.2    Forbin, F.3
  • 128
    • 84883525890 scopus 로고    scopus 로고
    • Cancer diagnosis and prognosis decoded by blood-based circulating microRNA signatures
    • Madhavan D, Cuk K, Burwinkel B, Yang R. Cancer diagnosis and prognosis decoded by blood-based circulating microRNA signatures. Front Genet. 2013;4:116.
    • (2013) Front Genet , vol.4 , pp. 116
    • Madhavan, D.1    Cuk, K.2    Burwinkel, B.3    Yang, R.4
  • 129
    • 84883030137 scopus 로고    scopus 로고
    • Serum miR-21 as a diagnostic and prognostic biomarker in colorectal cancer
    • Toiyama Y, Takahashi M, Hur K, et al. Serum miR-21 as a diagnostic and prognostic biomarker in colorectal cancer. J Natl Cancer Inst. 2013;105(12):849-59.
    • (2013) J Natl Cancer Inst , vol.105 , Issue.12 , pp. 849-859
    • Toiyama, Y.1    Takahashi, M.2    Hur, K.3
  • 130
    • 77349107376 scopus 로고    scopus 로고
    • DNA methylation markers in colorectal cancer
    • Kim MS, Lee J, Sidransky D. DNA methylation markers in colorectal cancer. Cancer Metastasis Rev. 2010;29(1):181-206.
    • (2010) Cancer Metastasis Rev , vol.29 , Issue.1 , pp. 181-206
    • Kim, M.S.1    Lee, J.2    Sidransky, D.3
  • 131
    • 53049087109 scopus 로고    scopus 로고
    • Genomic and epigenetic instability in colorectal cancer pathogenesis
    • Grady WM, Carethers JM. Genomic and epigenetic instability in colorectal cancer pathogenesis. Gastroenterology. 2008;135(4):1079-99.
    • (2008) Gastroenterology , vol.135 , Issue.4 , pp. 1079-1099
    • Grady, W.M.1    Carethers, J.M.2
  • 132
    • 33845608798 scopus 로고    scopus 로고
    • Classification of colorectal cancer based on correlation of clinical, morphological and molecular features
    • DOI 10.1111/j.1365-2559.2006.02549.x
    • Jass JR. Classification of colorectal cancer based on correlation of clinical, morphological and molecular features. Histopathology. 2007;50(1):113-30. (Pubitemid 44953403)
    • (2007) Histopathology , vol.50 , Issue.1 , pp. 113-130
    • Jass, J.R.1


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