Genetic aspects of non-polypoid colorectal neoplasms

Gastrointestinal Endoscopy Clinics of North America

Volumn 20, Issue 3, 2010, Pages 573-578

  Kahng, Lyn Sue ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Colorectal cancer; Molecular genetics; Non polypoid colorectal neoplasms; Research

Indexed keywords

RAS PROTEIN;

CANCER GENETICS; CANCER MORPHOLOGY; CANCER RESEARCH; COLORECTAL CANCER; COLORECTAL TUMOR; EXPERIMENTAL MODEL; GENE MUTATION; GENETIC DISORDER; GENETIC TRANSCRIPTION; GENOMICS; HISTOPATHOLOGY; HUMAN; METHYLATION; MICROSATELLITE INSTABILITY; NONHUMAN; NONPOLYPOID COLORECTAL TUMOR; ONCOGENE K RAS; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; REVIEW;

COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MICROSATELLITE INSTABILITY; MOLECULAR BIOLOGY; PHENOTYPE; PROGNOSIS; PROTO-ONCOGENE PROTEINS; RAS PROTEINS; RISK FACTORS; UNITED STATES;

EID: 77955064974     PISSN: 10525157     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.giec.2010.03.004     Document Type: Review

References (32)

1. Fearon E.R., Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990, 61:759-767.
2. Jass J.R. Classification of colorectal cancer based on correlation of clinical, morphological, and molecular features. Histopathology 2007, 50:113-130.
3. Kaneko K., Fujii T., Kato S., et al. Growth patterns and genetic changes of colorectal carcinoma. Jpn J Clin Oncol 1998, 28:196-201.
4. Olschwang S., Slezak P., Roze M., et al. Somatically acquired genetic alterations in flat colorectal neoplasias. Int J Cancer 1998, 77:366-369.
5. Umetani N., Sasaki S., Masaki T., et al. Involvement of APC and K-ras mutation in nonpolypoid colorectal tumorigenesis. Br J Cancer 2000, 82:9-15.
6. Hiraoka S., Kato J., Tatsukawa M., et al. Laterally spreading type of colorectal adenoma exhibits a unique methylation phenotype and K-ras mutations. Gastroenterology 2006, 131:379-389.
7. Mukawa K., Fujii S., Takeda J., et al. Analysis of K-ras mutations and expression of cyclooxygenase-2 and gastrin protein in laterally spreading tumors. J Gastroenterol Hepatol 2005, 20:1584-1590.
8. Takahashi T., Nosho K., Yamamoto H., et al. Flat-type colorectal advanced adenomas (laterally spreading tumors) have different genetic and epigenetic alterations from protruded-type advanced adenomas. Mod Pathol 2007, 20:139-147.
9. Yashiro M., Carethers J.M., Laghi L., et al. Genetic pathways in the evolution of morphologically distinct colorectal neoplasms. Cancer Res 2001, 61:2676-2683.
10. Donninger H., Vos M.D., Clark G.J. The RASSF1A tumor suppressor. J Cell Sci 2007, 120:3163-3172.
11. Richter A.M., Pfeifer G.P., Dammann R.H. The RASSF proteins in cancer; from epigenetic silencing to functional characterization. Biochim Biophys Acta 2009, 1796:114-128.
12. van Engeland M., Roemen G.M., Brink M., et al. K-ras mutations and RASSF1A promoter methylation in colorectal cancer. Oncogene 2002, 21:3792-3795.
13. Oliveira C., Velho S., Domingo E., et al. Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer. Oncogene 2005, 24:7630-7634.
14. Sakamoto N., Terai T., Ajioka Y., et al. Frequent hypermethylation of RASSF1A in early flat-type colorectal tumors. Oncogene 2004, 23:8900-8907.
15. Noda H., Kato Y., Yoshikawa H., et al. Frequent involvement of ras-signaling pathways in both polypoid-type and flat-type early stage colorectal cancers. J Exp Clin Cancer Res 2006, 25:235-242.
16. Nosho K., Yamamoto H., Takahashi T., et al. Genetic and epigenetic profiling in early colorectal tumors and prediction of invasive potential in pT1 (early invasive) colorectal cancers. Carcinogenesis 2007, 28:1364-1370.
17. Hirata I., Wang F.Y., Murano M., et al. Histopathological and genetic differences between polypoid and nonpolypoid submucosal colorectal carcinoma. World J Gastroenterol 2007, 13:2048-2052.
18. Rubio C.A., Rodensjo M. Mutation of p53 tumor suppressor gene in flat neoplastic lesions of the colorectal mucosa. Dis Colon Rectum 1996, 39:143-147.
19. Saitoh Y., Waxman I., West A.B., et al. Prevalence and distinctive biologic features of flat colorectal adenomas in a North American population. Gastroenterology 2001, 120:1657-1665.
20. Watanabe T., Muto T. Colorectal carcinogenesis based on molecular biology of early colorectal cancer, with special reference to nonpolypoid (superficial) lesions. World J Surg 2000, 24:1091-1097.
21. Orita H., Sakamoto N., Ajioka Y., et al. Allelic loss analysis of early stage flat-type colorectal tumors. Ann Oncol 2006, 17:43-49.
22. Mueller J.D., Haegle N., Keller G., et al. Loss of heterozygosity and microsatellite instability in de novo versus ex-adenoma carcinomas of the colorectum. Am J Pathol 1998, 153:1977-1984.
23. Wlodarczyk J., Bethke B., Mueller E., et al. A comparative study of E-cadherin and stromelysin-3 expression in de novo and ex adenoma carcinoma of the colorectum. Virchows Arch 2001, 439:756-761.
24. Koga Y., Yao T., Hirahashi M., et al. Flat adenoma-carcinoma sequence with high-malignancy potential as demonstrated by CD10 and beta-catenin expression: a different pathway from the polypoid adenoma-carcinoma sequence. Histopathology 2008, 52:569-577.
25. Byrd J.C., Bresalier R.S. Mucins and mucin binding proteins in colorectal cancer. Cancer Metastasis Rev 2004, 23:77-99.
26. Ogawa T., Yoshida T., Tsuruta T., et al. Genetic instability on chromosome 17 in the epithelium of non-polypoid colorectal carcinomas compared to polypoid lesions. Cancer Sci 2006, 97:1335-1342.
27. Kinney T.P., Merel N., Hart J., et al. Microsatellite analysis of sporadic flat and depressed lesions of the colon. Dig Dis Sci 2005, 50:327-330.
28. Kita H., Hikichi Y., Hikami K., et al. Differential gene expression between flat adenoma and normal mucosa in the colon in a microarray analysis. J Gastroenterol 2006, 41:1053-1063.
29. Kirimlioglu H., Kirimlioglu V., Yilmaz S., et al. Role of matrix metalloproteinase-7 in colorectal adenomas. Dig Dis Sci 2006, 51:2068-2072.
30. Maurel J., Nadal C., Garcia-Albeniz X., et al. Serum matrix metalloproteinase 7 levels identifies poor prognosis advanced colorectal cancer patients. Int J Cancer 2007, 121:1066-1071.
31. Birkenkamp-Demtroder K., Olesen S.H., Sorensen F.B., et al. Differential gene expression in colon cancer of the caecum versus the sigmoid and rectosigmoid. Gut 2005, 54:374-384.
32. Uronis J.M., Herfarth H.H., Rubinas T.C., et al. Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage. Cancer Res 2007, 67:11594-11600.