메뉴 건너뛰기




Volumn 6, Issue 8, 2014, Pages 2210-2228

Cancer cell growth inhibitory effect of bee venom via increase of death receptor 3 expression and inactivation of NF-kappa B in NSCLC cells

Author keywords

Apoptosis; Bee venom; Death receptors; NF B

Indexed keywords

4', 6 DIAMIDINO 2 PHENYLINDOLE; BEE VENOM; BETA ACTIN; CASPASE 3; CASPASE 9; CISPLATIN; DEATH RECEPTOR 3; DEATH RECEPTOR 4; DOCETAXEL; FAS ANTIBODY; HISTONE H1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P50; SMALL INTERFERING RNA; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; TNFRSF25 PROTEIN, HUMAN;

EID: 84904989542     PISSN: None     EISSN: 20726651     Source Type: Journal    
DOI: 10.3390/toxins6082210     Document Type: Article
Times cited : (59)

References (49)
  • 4
    • 33751104270 scopus 로고    scopus 로고
    • Multidrug resistance in small cell lung cancer: Expression of P-glycoprotein, multidrug resistance protein 1 and lung resistance protein in chemo-naive patients and in relapsed disease
    • Triller, N.; Korosec, P.; Kern, I.; Kosnik, M.; Debeljak, A. Multidrug resistance in small cell lung cancer: Expression of P-glycoprotein, multidrug resistance protein 1 and lung resistance protein in chemo-naive patients and in relapsed disease. Lung Cancer 2006, 54, 235-240.
    • (2006) Lung Cancer , vol.54 , pp. 235-240
    • Triller, N.1    Korosec, P.2    Kern, I.3    Kosnik, M.4    Debeljak, A.5
  • 5
    • 1642363983 scopus 로고    scopus 로고
    • A chemically induced model for squamous cell carcinoma of the lung in mice: Histopathology and strain susceptibility
    • Wang, Y.; Zhang, Z.; Yan, Y.; Lemon, W.J.; LaRegina, M.; Morrison, C.; Lubet, R.; You, M. A chemically induced model for squamous cell carcinoma of the lung in mice: Histopathology and strain susceptibility. Cancer Res. 2004, 64, 1647-1654.
    • (2004) Cancer Res , vol.64 , pp. 1647-1654
    • Wang, Y.1    Zhang, Z.2    Yan, Y.3    Lemon, W.J.4    Laregina, M.5    Morrison, C.6    Lubet, R.7    You, M.8
  • 6
    • 8444239358 scopus 로고    scopus 로고
    • Antiarthritic effect of bee venom: Inhibition of inflammation mediator generation by suppression of NF-κB through interaction with the p50 subunit
    • Park, H.J.; Lee, S.H.; Son, D.J.; Oh, K.W.; Kim, K.H.; Song, H.S.; Kim, G.J.; Oh, G.T.; Yoon, D.Y.; Hong, J.T. Antiarthritic effect of bee venom: Inhibition of inflammation mediator generation by suppression of NF-κB through interaction with the p50 subunit. Arthritis Rheum. 2004, 50, 3504-3515.
    • (2004) Arthritis Rheum , vol.50 , pp. 3504-3515
    • Park, H.J.1    Lee, S.H.2    Son, D.J.3    Oh, K.W.4    Kim, K.H.5    Song, H.S.6    Kim, G.J.7    Oh, G.T.8    Yoon, D.Y.9    Hong, J.T.10
  • 7
    • 79953729368 scopus 로고    scopus 로고
    • Anti-cancer effect of bee venom in prostate cancer cells through activation of caspase pathway via inactivation of NF-κB
    • Park, M.H.; Choi, M.S.; Kwak, D.H.; Oh, K.W.; Yoon do, Y.; Han, S.B.; Song, H.S.; Song, M.J.; Hong, J.T. Anti-cancer effect of bee venom in prostate cancer cells through activation of caspase pathway via inactivation of NF-κB. Prostate 2011, 71, 801-812.
    • (2011) Prostate , vol.71 , pp. 801-812
    • Park, M.H.1    Choi, M.S.2    Kwak, D.H.3    Oh, K.W.4    do Yoon, Y.5    Han, S.B.6    Song, H.S.7    Song, M.J.8    Hong, J.T.9
  • 8
    • 84855417569 scopus 로고    scopus 로고
    • Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells through induction of death receptors and inhibition of JAK2/STAT3 pathway
    • Jo, M.; Park, M.H.; Kollipara, P.S.; An, B.J.; Song, H.S.; Han, S.B.; Kim, J.H.; Song, M.J.; Hong, J.T. Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells through induction of death receptors and inhibition of JAK2/STAT3 pathway. Toxicol. Appl. Pharmacol. 2012, 258, 72-81.
    • (2012) Toxicol. Appl. Pharmacol , vol.258 , pp. 72-81
    • Jo, M.1    Park, M.H.2    Kollipara, P.S.3    An, B.J.4    Song, H.S.5    Han, S.B.6    Kim, J.H.7    Song, M.J.8    Hong, J.T.9
  • 9
    • 63649143578 scopus 로고    scopus 로고
    • Melittin, a major component of bee venom, sensitizes human hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating CaMKII-TAK1-JNK/p38 and inhibiting IκBalpha kinase-NFκB
    • Wang, C.; Chen, T.; Zhang, N.; Yang, M.; Li, B.; Lu, X.; Cao, X.; Ling, C. Melittin, a major component of bee venom, sensitizes human hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating CaMKII-TAK1-JNK/p38 and inhibiting IκBalpha kinase-NFκB. J. Biol. Chem. 2009, 284, 3804-3813.
    • (2009) J. Biol. Chem , vol.284 , pp. 3804-3813
    • Wang, C.1    Chen, T.2    Zhang, N.3    Yang, M.4    Li, B.5    Lu, X.6    Cao, X.7    Ling, C.8
  • 10
    • 84855201768 scopus 로고    scopus 로고
    • Bee venom induces apoptosis through intracellular Ca2+ -modulated intrinsic death pathway in human bladder cancer cells
    • Ip, S.W.; Chu, Y.L.; Yu, C.S.; Chen, P.Y.; Ho, H.C.; Yang, J.S.; Huang, H.Y.; Chueh, F.S.; Lai, T.Y.; Chung, J.G. Bee venom induces apoptosis through intracellular Ca2+ -modulated intrinsic death pathway in human bladder cancer cells. Int. J. Urol. 2012, 19, 61-70.
    • (2012) Int. J. Urol , vol.19 , pp. 61-70
    • Ip, S.W.1    Chu, Y.L.2    Yu, C.S.3    Chen, P.Y.4    Ho, H.C.5    Yang, J.S.6    Huang, H.Y.7    Chueh, F.S.8    Lai, T.Y.9    Chung, J.G.10
  • 11
    • 79957551900 scopus 로고    scopus 로고
    • Role of cell-death ligand-receptor system of granulosa cells in selective follicular atresia in porcine ovary
    • Inoue, N.; Matsuda, F.; Goto, Y.; Manabe, N. Role of cell-death ligand-receptor system of granulosa cells in selective follicular atresia in porcine ovary. J. Reprod. Dev. 2011, 57, 169-175.
    • (2011) J. Reprod. Dev , vol.57 , pp. 169-175
    • Inoue, N.1    Matsuda, F.2    Goto, Y.3    Manabe, N.4
  • 12
    • 33644647055 scopus 로고    scopus 로고
    • Adenovirus E1A reverses the resistance of normal primary human lung fibroblast cells to TRAIL through DR5 upregulation and caspase 8-dependent pathway
    • Zhu, H.; Ling, W.; Hu, B.; Su, Y.; Qiu, S.; Xiao, W.; Qi, Y. Adenovirus E1A reverses the resistance of normal primary human lung fibroblast cells to TRAIL through DR5 upregulation and caspase 8-dependent pathway. Cancer Biol. Ther. 2006, 5, 180-188.
    • (2006) Cancer Biol. Ther , vol.5 , pp. 180-188
    • Zhu, H.1    Ling, W.2    Hu, B.3    Su, Y.4    Qiu, S.5    Xiao, W.6    Qi, Y.7
  • 13
    • 0035914468 scopus 로고    scopus 로고
    • A Fas-associated death domain protein-dependent mechanism mediates the apoptotic action of non-steroidal anti-inflammatory drugs in the human leukemic Jurkat cell line
    • Han, Z.; Pantazis, P.; Wyche, J.H.; Kouttab, N.; Kidd, V.J.; Hendrickson, E.A. A Fas-associated death domain protein-dependent mechanism mediates the apoptotic action of non-steroidal anti-inflammatory drugs in the human leukemic Jurkat cell line. J. Biol. Chem. 2001, 276, 38748-38754.
    • (2001) J. Biol. Chem , vol.276 , pp. 38748-38754
    • Han, Z.1    Pantazis, P.2    Wyche, J.H.3    Kouttab, N.4    Kidd, V.J.5    Hendrickson, E.A.6
  • 14
    • 0035884187 scopus 로고    scopus 로고
    • Sulindac sulfide-induced apoptosis involves death receptor 5 and the caspase 8-dependent pathway in human colon and prostate cancer cells
    • Huang, Y.; He, Q.; Hillman, M.J.; Rong, R.; Sheikh, M.S. Sulindac sulfide-induced apoptosis involves death receptor 5 and the caspase 8-dependent pathway in human colon and prostate cancer cells. Cancer Res. 2001, 61, 6918-6924.
    • (2001) Cancer Res , vol.61 , pp. 6918-6924
    • Huang, Y.1    He, Q.2    Hillman, M.J.3    Rong, R.4    Sheikh, M.S.5
  • 15
    • 58149202128 scopus 로고    scopus 로고
    • Is NF-κB a good target for cancer therapy? Hopes and pitfalls
    • Baud, V.; Karin, M. Is NF-κB a good target for cancer therapy? Hopes and pitfalls. Nat. Rev. Drug Discov. 2009, 8, 33-40.
    • (2009) Nat. Rev. Drug Discov , vol.8 , pp. 33-40
    • Baud, V.1    Karin, M.2
  • 16
    • 0030927167 scopus 로고    scopus 로고
    • Constitutive activation of NF-κB during progression of breast cancer to hormone-independent growth
    • Nakshatri, H.; Bhat-Nakshatri, P.; Martin, D.A.; Goulet, R.J., Jr.; Sledge, G.W., Jr. Constitutive activation of NF-κB during progression of breast cancer to hormone-independent growth. Mol. Cell. Biol. 1997, 17, 3629-3639.
    • (1997) Mol. Cell. Biol , vol.17 , pp. 3629-3639
    • Nakshatri, H.1    Bhat-Nakshatri, P.2    Martin, D.A.3    Goulet Jr., R.J.4    Sledge Jr., G.W.5
  • 17
    • 0036546501 scopus 로고    scopus 로고
    • NF-B in cancer: From innocent bystander to major culprit
    • Karin, M.; Cao, Y.; Greten, F.R.; Li, Z.W. NF-B in cancer: From innocent bystander to major culprit. Nat. Rev. Cancer 2002, 2, 301-310.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 18
    • 84866373872 scopus 로고    scopus 로고
    • Insertion of a nuclear factor κ B DNA nuclear-targeting sequence potentiates suicide gene therapy efficacy in lung cancer cell lines
    • Cramer, F.; Christensen, C.L.; Poulsen, T.T.; Badding, M.A.; Dean, D.A.; Poulsen, H.S. Insertion of a nuclear factor κ B DNA nuclear-targeting sequence potentiates suicide gene therapy efficacy in lung cancer cell lines. Cancer Gene Ther. 2012, 19, 675-683.
    • (2012) Cancer Gene Ther , vol.19 , pp. 675-683
    • Cramer, F.1    Christensen, C.L.2    Poulsen, T.T.3    Badding, M.A.4    Dean, D.A.5    Poulsen, H.S.6
  • 19
    • 65649109390 scopus 로고    scopus 로고
    • Genistein enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitors and inhibits nuclear factor κ B in nonsmall cell lung cancer cell lines
    • Gadgeel, S.M.; Ali, S.; Philip, P.A.; Wozniak, A.; Sarkar, F.H. Genistein enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitors and inhibits nuclear factor κ B in nonsmall cell lung cancer cell lines. Cancer 2009, 115, 2165-2176.
    • (2009) Cancer , vol.115 , pp. 2165-2176
    • Gadgeel, S.M.1    Ali, S.2    Philip, P.A.3    Wozniak, A.4    Sarkar, F.H.5
  • 20
    • 33144456303 scopus 로고    scopus 로고
    • Resveratrol enhances radiosensitivity of human non-small cell lung cancer NCI-H838 cells accompanied by inhibition of nuclear factor-κ B activation
    • Liao, H.F.; Kuo, C.D.; Yang, Y.C.; Lin, C.P.; Tai, H.C.; Chen, Y.Y.; Chen, Y.J. Resveratrol enhances radiosensitivity of human non-small cell lung cancer NCI-H838 cells accompanied by inhibition of nuclear factor-κ B activation. J. Radiat. Res. 2005, 46, 387-393.
    • (2005) J. Radiat. Res , vol.46 , pp. 387-393
    • Liao, H.F.1    Kuo, C.D.2    Yang, Y.C.3    Lin, C.P.4    Tai, H.C.5    Chen, Y.Y.6    Chen, Y.J.7
  • 22
    • 67649573993 scopus 로고    scopus 로고
    • Thiacremonone augments chemotherapeutic agent-induced growth inhibition in human colon cancer cells through inactivation of nuclear factorκ-B
    • Ban, J.O.; Lee, H.S.; Jeong, H.S.; Song, S.; Hwang, B.Y.; Moon, D.C.; Yoon do, Y.; Han, S.B.; Hong, J.T. Thiacremonone augments chemotherapeutic agent-induced growth inhibition in human colon cancer cells through inactivation of nuclear factorκ-B. Mol. Cancer Res. 2009, 7, 870-879.
    • (2009) Mol. Cancer Res , vol.7 , pp. 870-879
    • Ban, J.O.1    Lee, H.S.2    Jeong, H.S.3    Song, S.4    Hwang, B.Y.5    Moon, D.C.6    do Yoon, Y.7    Han, S.B.8    Hong, J.T.9
  • 23
    • 23044498269 scopus 로고    scopus 로고
    • Inactivation of nuclear factor κB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells
    • Li, Y.; Ahmed, F.; Ali, S.; Philip, P.A.; Kucuk, O.; Sarkar, F.H. Inactivation of nuclear factor κB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells. Cancer Res. 2005, 65, 6934-6942.
    • (2005) Cancer Res , vol.65 , pp. 6934-6942
    • Li, Y.1    Ahmed, F.2    Ali, S.3    Philip, P.A.4    Kucuk, O.5    Sarkar, F.H.6
  • 24
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-κB transcription factors
    • Pahl, H.L. Activators and target genes of Rel/NF-κB transcription factors. Oncogene 1999, 18, 6853-6866.
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 25
    • 34548522918 scopus 로고    scopus 로고
    • Inhibition of cell growth and induction of apoptosis via inactivation of NF-κB by a sulfurcompound isolated from garlic in human colon cancer cells
    • Ban, J.O.; Yuk, D.Y.; Woo, K.S.; Kim, T.M.; Lee, U.S.; Jeong, H.S.; Kim, D.J.; Chung, Y.B.; Hwang, B.Y.; Oh, K.W., et al. Inhibition of cell growth and induction of apoptosis via inactivation of NF-κB by a sulfurcompound isolated from garlic in human colon cancer cells. J. Pharmacol. Sci. 2007, 104, 374-383.
    • (2007) J. Pharmacol. Sci , vol.104 , pp. 374-383
    • Ban, J.O.1    Yuk, D.Y.2    Woo, K.S.3    Kim, T.M.4    Lee, U.S.5    Jeong, H.S.6    Kim, D.J.7    Chung, Y.B.8    Hwang, B.Y.9    Oh, K.W.10
  • 26
    • 76549121864 scopus 로고    scopus 로고
    • Combination of ginsenoside rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of nf-κb
    • Kim, S.M.; Lee, S.Y.; Cho, J.S.; Son, S.M.; Choi, S.S.; Yun, Y.P.; Yoo, H.S.; Yoon do, Y.; Oh, K.W.; Han, S.B., et al. Combination of ginsenoside rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of nf-κb. Eur. J. Pharmacol. 2010, 631, 1-9.
    • (2010) Eur. J. Pharmacol , vol.631 , pp. 1-9
    • Kim, S.M.1    Lee, S.Y.2    Cho, J.S.3    Son, S.M.4    Choi, S.S.5    Yun, Y.P.6    Yoo, H.S.7    do Yoon, Y.8    Oh, K.W.9    Han, S.B.10
  • 27
    • 70350475246 scopus 로고    scopus 로고
    • Obovatol enhances docetaxel-induced prostate and colon cancer cell death through inactivation of nuclear transcription factor-κb
    • Lee, S.Y.; Cho, J.S.; Yuk, D.Y.; Moon, D.C.; Jung, J.K.; Yoo, H.S.; Lee, Y.M.; Han, S.B.; Oh, K.W.; Hong, J.T. Obovatol enhances docetaxel-induced prostate and colon cancer cell death through inactivation of nuclear transcription factor-κb. J. Pharmacol. Sci. 2009, 111, 124-136.
    • (2009) J. Pharmacol. Sci , vol.111 , pp. 124-136
    • Lee, S.Y.1    Cho, J.S.2    Yuk, D.Y.3    Moon, D.C.4    Jung, J.K.5    Yoo, H.S.6    Lee, Y.M.7    Han, S.B.8    Oh, K.W.9    Hong, J.T.10
  • 28
    • 84862337185 scopus 로고    scopus 로고
    • Bee venom in cancer therapy
    • Orsolic, N. Bee venom in cancer therapy. Cancer Metastasis Rev. 2012, 31, 173-194.
    • (2012) Cancer Metastasis Rev , vol.31 , pp. 173-194
    • Orsolic, N.1
  • 30
    • 33749679450 scopus 로고    scopus 로고
    • Key regulators in bee venom-induced apoptosis are Bcl-2 and caspase-3 in human leukemic U937 cells through downregulation of ERK and Akt
    • Moon, D.O.; Park, S.Y.; Heo, M.S.; Kim, K.C.; Park, C.; Ko, W.S.; Choi, Y.H.; Kim, G.Y. Key regulators in bee venom-induced apoptosis are Bcl-2 and caspase-3 in human leukemic U937 cells through downregulation of ERK and Akt. Int. Immunopharmacol. 2006, 6, 1796-1807.
    • (2006) Int. Immunopharmacol , vol.6 , pp. 1796-1807
    • Moon, D.O.1    Park, S.Y.2    Heo, M.S.3    Kim, K.C.4    Park, C.5    Ko, W.S.6    Choi, Y.H.7    Kim, G.Y.8
  • 31
    • 0033732562 scopus 로고    scopus 로고
    • What can venom phospholipases A(2) tell us about the functional diversity of mammalian secreted phospholipases A(2)?
    • Valentin, E.; Lambeau, G. What can venom phospholipases A(2) tell us about the functional diversity of mammalian secreted phospholipases A(2)? Biochimie 2000, 82, 815-831.
    • (2000) Biochimie , vol.82 , pp. 815-831
    • Valentin, E.1    Lambeau, G.2
  • 32
    • 70449393157 scopus 로고    scopus 로고
    • In vitro- and in vivo-targeted tumor lysis by an MMP2 cleavable melittin-LAP fusion protein
    • Holle, L.; Song, W.; Holle, E.; Wei, Y.; Li, J.; Wagner, T.E.; Yu, X. In vitro- and in vivo-targeted tumor lysis by an MMP2 cleavable melittin-LAP fusion protein. Int. J. Oncol. 2009, 35, 829-835.
    • (2009) Int. J. Oncol , vol.35 , pp. 829-835
    • Holle, L.1    Song, W.2    Holle, E.3    Wei, Y.4    Li, J.5    Wagner, T.E.6    Yu, X.7
  • 33
    • 77951210918 scopus 로고    scopus 로고
    • Bee venom inhibits tumor angiogenesis and metastasis by inhibiting tyrosine phosphorylation of VEGFR-2 in LLC-tumor-bearing mice
    • Huh, J.E.; Baek, Y.H.; Lee, M.H.; Choi, D.Y.; Park, D.S.; Lee, J.D. Bee venom inhibits tumor angiogenesis and metastasis by inhibiting tyrosine phosphorylation of VEGFR-2 in LLC-tumor-bearing mice. Cancer Lett. 2010, 292, 98-110.
    • (2010) Cancer Lett , vol.292 , pp. 98-110
    • Huh, J.E.1    Baek, Y.H.2    Lee, M.H.3    Choi, D.Y.4    Park, D.S.5    Lee, J.D.6
  • 35
    • 79956016364 scopus 로고    scopus 로고
    • Urothelial cancer cell response to combination therapy of gemcitabine and TRAIL
    • Moibi, J.A.; Mak, A.L.; Sun, B.; Moore, R.B. Urothelial cancer cell response to combination therapy of gemcitabine and TRAIL. Int. J. Oncol. 2011, 39, 61-71.
    • (2011) Int. J. Oncol , vol.39 , pp. 61-71
    • Moibi, J.A.1    Mak, A.L.2    Sun, B.3    Moore, R.B.4
  • 36
    • 77956113476 scopus 로고    scopus 로고
    • A kava chalcone, induces apoptosis via up-regulation of death-receptor 5 and Bim expression in androgen receptor negative, hormonal refractory prostate cancer cell lines and reduces tumor growth
    • Tang, Y.; Li, X.; Liu, Z.; Simoneau, A.R.; Xie, J.; Zi, X.; Flavokawain, B. A kava chalcone, induces apoptosis via up-regulation of death-receptor 5 and Bim expression in androgen receptor negative, hormonal refractory prostate cancer cell lines and reduces tumor growth. J. Int. Cancer 2010, 127, 1758-1768.
    • (2010) J. Int. Cancer , vol.127 , pp. 1758-1768
    • Tang, Y.1    Li, X.2    Liu, Z.3    Simoneau, A.R.4    Xie, J.5    Zi, X.6    Flavokawain, B.7
  • 37
    • 77956374604 scopus 로고    scopus 로고
    • A fourth generation GnRH antagonist, induces apoptosis in hormone refractory androgen receptor negative prostate cancer cells modulating expression and activity of death receptors
    • Festuccia, C.; Dondi, D.; Piccolella, M.; Locatelli, A.; Gravina, G.L.; Tombolini, V.; Ozarelix, M.M. A fourth generation GnRH antagonist, induces apoptosis in hormone refractory androgen receptor negative prostate cancer cells modulating expression and activity of death receptors. Prostate 2010, 70, 1340-1349.
    • (2010) Prostate , vol.70 , pp. 1340-1349
    • Festuccia, C.1    Dondi, D.2    Piccolella, M.3    Locatelli, A.4    Gravina, G.L.5    Tombolini, V.6    Ozarelix, M.M.7
  • 39
    • 0033596127 scopus 로고    scopus 로고
    • Control of apoptosis by Rel/NF-κB transcription factors
    • Barkett, M.; Gilmore, T.D. Control of apoptosis by Rel/NF-κB transcription factors. Oncogene 1999, 18, 6910-6924.
    • (1999) Oncogene , vol.18 , pp. 6910-6924
    • Barkett, M.1    Gilmore, T.D.2
  • 40
    • 84864434810 scopus 로고    scopus 로고
    • Effect of NF-κB on inhibition of non-small cell lung cancer cell cyclooxygenase-2 by brucine
    • Zhu, G.; Yin, F.; Deng, X. Effect of NF-κB on inhibition of non-small cell lung cancer cell cyclooxygenase-2 by brucine. China J. Chin. Mater. Med. 2012, 37, 1269-1273.
    • (2012) China J. Chin. Mater. Med , vol.37 , pp. 1269-1273
    • Zhu, G.1    Yin, F.2    Deng, X.3
  • 41
    • 0036164423 scopus 로고    scopus 로고
    • Inhibition of nuclear factor κB chemosensitizes non-small cell lung cancer through cytochrome c release and caspase activation
    • Jones, D.R.; Broad, R.M.; Comeau, L.D.; Parsons, S.J.; Mayo, M.W. Inhibition of nuclear factor κB chemosensitizes non-small cell lung cancer through cytochrome c release and caspase activation. J. Thorac. Cardiovasc. Surg. 2002, 123, 310-317.
    • (2002) J. Thorac. Cardiovasc. Surg , vol.123 , pp. 310-317
    • Jones, D.R.1    Broad, R.M.2    Comeau, L.D.3    Parsons, S.J.4    Mayo, M.W.5
  • 42
    • 79953727528 scopus 로고    scopus 로고
    • Acacetin inhibits the invasion and migration of human non-small cell lung cancer A549 cells by suppressing the p38alpha MAPK signaling pathway
    • Chien, S.T.; Lin, S.S.; Wang, C.K.; Lee, Y.B.; Chen, K.S.; Fong, Y.; Shih, Y.W. Acacetin inhibits the invasion and migration of human non-small cell lung cancer A549 cells by suppressing the p38alpha MAPK signaling pathway. Mol. Cell. Biochem. 2011, 350, 135-148.
    • (2011) Mol. Cell. Biochem , vol.350 , pp. 135-148
    • Chien, S.T.1    Lin, S.S.2    Wang, C.K.3    Lee, Y.B.4    Chen, K.S.5    Fong, Y.6    Shih, Y.W.7
  • 44
    • 70349881605 scopus 로고    scopus 로고
    • Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-κB
    • Murtaza, I.; Adhami, V.M.; Hafeez, B.B.; Saleem, M.; Mukhtar, H. Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-κB. Int. J. Cancer 2009, 125, 2465-2473.
    • (2009) Int. J. Cancer , vol.125 , pp. 2465-2473
    • Murtaza, I.1    Adhami, V.M.2    Hafeez, B.B.3    Saleem, M.4    Mukhtar, H.5
  • 45
    • 84874413050 scopus 로고    scopus 로고
    • Anti-proliferative effect of (E)-2,4-bis (p-hydroxyphenyl)-2-butenal by suppression of NF-κB and up regulation of DR5 via up-regulation of p38 MAPK in NSCLC
    • Kollipara, P.S.; Jeong, H.S.; Han, S.B.; Hong, J.T. Anti-proliferative effect of (E)-2,4-bis (p-hydroxyphenyl)-2-butenal by suppression of NF-κB and up regulation of DR5 via up-regulation of p38 MAPK in NSCLC. Br. J. Pharmacol. 2013, 168, 1471-1484.
    • (2013) Br. J. Pharmacol , vol.168 , pp. 1471-1484
    • Kollipara, P.S.1    Jeong, H.S.2    Han, S.B.3    Hong, J.T.4
  • 48
    • 80052772287 scopus 로고    scopus 로고
    • A novel parthenin analog exhibits anti-cancer activity: Activation of apoptotic signaling events through robust NO formation in human leukemia HL-60 cells
    • Kumar, A.; Malik, F.; Bhushan, S.; Shah, B.A.; Taneja, S.C.; Pal, H.C.; Wani, Z.A.; Mondhe, D.M.; Kaur, J.; Singh, J. A novel parthenin analog exhibits anti-cancer activity: Activation of apoptotic signaling events through robust NO formation in human leukemia HL-60 cells. Chem. Biol. Interact. 2011, 193, 204-215.
    • (2011) Chem. Biol. Interact , vol.193 , pp. 204-215
    • Kumar, A.1    Malik, F.2    Bhushan, S.3    Shah, B.A.4    Taneja, S.C.5    Pal, H.C.6    Wani, Z.A.7    Mondhe, D.M.8    Kaur, J.9    Singh, J.10
  • 49
    • 35848969354 scopus 로고    scopus 로고
    • Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization independent activation of the nuclear factor-κB/IκB kinase signal pathway
    • Lee, S.H.; Son, S.M.; Son, D.J.; Kim, S.M.; Kim, T.J.; Song, S.; Moon, D.C.; Lee, H.W.; Ryu, J.C.; Yoon, D.Y., et al. Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization independent activation of the nuclear factor-κB/IκB kinase signal pathway. Mol. Cancer Ther. 2007, 6, 2786-2797.
    • (2007) Mol. Cancer Ther , vol.6 , pp. 2786-2797
    • Lee, S.H.1    Son, S.M.2    Son, D.J.3    Kim, S.M.4    Kim, T.J.5    Song, S.6    Moon, D.C.7    Lee, H.W.8    Ryu, J.C.9    Yoon, D.Y.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.