Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells through induction of death receptors and inhibition of JAK2/STAT3 pathway

Toxicology and Applied Pharmacology

Volumn 258, Issue 1, 2012, Pages 72-81

  Jo, Miran ^a   Park, Mi Hee ^a   Kollipara, Pushpa Saranya ^a   An, Byeong Jun ^b   Song, Ho Sueb ^b   Han, Sang Bae ^a   Kim, Jang Heub ^c   Song, Min Jong ^c   Hong, Jin Tae ^a  

^a Chungbuk National University   (South Korea)

^b Gachon University   (South Korea)

^c The Catholic University of Korea   (South Korea)

Author keywords

Bee venom; Death receptor; JAK STAT3; Ovarian cancer

Indexed keywords

BEE VENOM; CASPASE 3; CASPASE 8; DEATH RECEPTOR; DEATH RECEPTOR 3; DEATH RECEPTOR 6; JANUS KINASE 2; MELITTIN; PROTEIN BAX; SMALL INTERFERING RNA; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL DEATH; CELL VIABILITY; CONCENTRATION RESPONSE; DOWN REGULATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; OVARY CANCER; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BEE VENOMS; FEMALE; HUMANS; JANUS KINASE 2; MELITTEN; OVARIAN NEOPLASMS; RECEPTORS, DEATH DOMAIN; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

APOIDEA;

EID: 84855417569     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.10.009     Document Type: Article

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