Isolation, structure elucidation and antibacterial activity of a new tetramic acid, ascosetin

Journal of Antibiotics

Volumn 67, Issue 7, 2014, Pages 527-531

  Ondeyka, John G ^a   Smith, Scott K ^a   Zink, Deborah L ^a   Vicente, Francisca ^b   Basilio, Angela ^b   Bills, Gerald F ^b   Polishook, Jon D ^a   Garlisi, Charles ^a   McGuinness, Debra ^a   Smith, Elizabeth ^a   Qiu, Hongchen ^a   Gill, Charles J ^a   Donald, Robert Gk ^a   Phillips, John W ^a   Goetz, Michael A ^a   Singh, Sheo B ^a,c  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Medical affairs Merck sharp and Dohme ltd   (Spain)

^c SBS Pharma Consulting LLC   (United States)

Author keywords

antibacterial; ascomycetes; ascosetin; Staphylococcus aureus fitness test (SaFT); tetramic acid

Indexed keywords

ANTI-BACTERIAL AGENTS; ASCOMYCOTA; HAEMOPHILUS INFLUENZAE; MAGNETIC RESONANCE SPECTROSCOPY; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MOLECULAR CONFORMATION; PYRROLIDINONES; STAPHYLOCOCCUS AUREUS;

EID: 84904958719     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2014.33     Document Type: Article

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