CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche

Blood

Volumn 124, Issue 4, 2014, Pages 519-529

  Chitteti, Brahmananda Reddy ^a   Kobayashi, Michihiro ^b   Cheng, Yinghua ^c   Zhang, Huajia ^b   Poteat, Bradley A ^a   Broxmeyer, Hal E ^d   Pelus, Louis M ^d   Hanenberg, Helmut ^b   Zollman, Amy ^b   Kamocka, Malgorzata M ^b   Carlesso, Nadia ^b   Cardoso, Angelo A ^a   Kacena, Melissa A ^c,e   Srour, Edward F ^a,b,d,e  

^a Division of Hematology and Oncology   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Veterinary Surgery   (United States)

^d Depts Microbiol Immunol and Med   (United States)

^e INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; CD150 ANTIGEN; GRANULOCYTE COLONY STIMULATING FACTOR; STAT3 PROTEIN;

ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN FUNCTION; ARTICLE; BINDING SITE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL FATE; CELL INTERACTION; CELL LINEAGE; CELL POPULATION; CELL PROTECTION; CELL STRESS; CHIMERA; CONTROLLED STUDY; ENGRAFTMENT; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN INTERACTION; RADIATION PROTECTION; SIDE POPULATION CELL; STEM CELL NICHE;

ACTIVATED-LEUKOCYTE CELL ADHESION MOLECULE; ANIMALS; ANTIGENS, CD; BIOLOGICAL MARKERS; BONE MARROW CELLS; CHROMATIN IMMUNOPRECIPITATION; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELLS; HUMANS; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, SCID; RECEPTORS, CELL SURFACE; STEM CELL NICHE;

EID: 84904905303     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-03-565721     Document Type: Article

References (38)

1. Calvi LM, Adams GB, Weibrecht KW, et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature. 2003;425(6960):841-846. (Pubitemid 37351468)
2. Chitteti BR, Cheng YH, Poteat B, et al. Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function. Blood. 2010;115(16): 3239-3248.
3. Zhang J, Niu C, Ye L, et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature. 2003;425(6960):836-841. (Pubitemid 37351467)
4. Chitteti BR, Cheng YH, Streicher DA, et al. Osteoblast lineage cells expressing high levels of Runx2 enhance hematopoietic progenitor cell proliferation and function. J Cell Biochem. 2010; 111(2):284-294.
5. Chitteti BR, Cheng YH, Kacena MA, Srour EF. Hierarchical organization of osteoblasts reveals the significant role of CD166 in hematopoietic stem cell maintenance and function. Bone. 2013; 54(1):58-67.
6. Nakamura Y, Arai F, Iwasaki H, et al. Isolation and characterization of endosteal niche cell populations that regulate hematopoietic stem cells. Blood. 2010;116(9):1422-1432.
7. Bowen MA, Bajorath J, D'Egidio M, et al. Characterization of mouse ALCAM (CD166): the CD6-binding domain is conserved in different homologs and mediates cross-species binding. Eur J Immunol. 1997;27(6):1469-1478. (Pubitemid 27254840)
8. Uchida N, Yang Z, Combs J, et al. The characterization, molecular cloning, and expression of a novel hematopoietic cell antigen from CD34+ human bone marrow cells. Blood. 1997;89(8):2706-2716. (Pubitemid 27172555)
9. Cortés F, Deschaseaux F, Uchida N, et al. HCA, an immunoglobulin-like adhesion molecule present on the earliest human hematopoietic precursor cells, is also expressed by stromal cells in blood-forming tissues. Blood. 1999;93(3): 826-837. (Pubitemid 29067847)
10. Ohneda O, Ohneda K, Arai F, et al. ALCAM (CD166): its role in hematopoietic and endothelial development. Blood. 2001;98(7):2134-2142.
11. Cheng YH, Chitteti BR, Streicher DA, et al. Impact of maturational status on the ability of osteoblasts to enhance the hematopoietic function of stem and progenitor cells. J Bone Miner Res. 2011; 26(5):1111-1121.
12. Jeannet R, Cai Q, Liu H, Vu H, Kuo YH. Alcam regulates long-term hematopoietic stem cell engraftment and self-renewal. Stem Cells. 2013; 31(3):560-571.
13. Jetmore A, Plett PA, Tong X, et al. Homing efficiency, cell cycle kinetics, and survival of quiescent and cycling human CD34(+) cells transplanted into conditioned NOD/SCID recipients. Blood. 2002;99(5):1585-1593. (Pubitemid 34533030)
14. Fukuda S, Bian H, King AG, Pelus LM. The chemokine GRObeta mobilizes early hematopoietic stem cells characterized by enhanced homing and engraftment. Blood. 2007; 110(3):860-869. (Pubitemid 47267422)
15. Kiel MJ, Yilmaz OH, Iwashita T, Yilmaz OH, Terhorst C, Morrison SJ. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell. 2005;121(7):1109-1121. (Pubitemid 40884400)
16. Benveniste P, Frelin C, Janmohamed S, et al. Intermediate-term hematopoietic stem cells with extended but time-limited reconstitution potential. Cell Stem Cell. 2010;6(1):48-58.
17. Harrison DE, Astle CM. Short- and long-term multilineage repopulating hematopoietic stem cells in late fetal and newborn mice: models for human umbilical cord blood. Blood. 1997;90(1): 174-181. (Pubitemid 27276560)
18. Weksberg DC, Chambers SM, Boles NC, Goodell MA. CD150-side population cells represent a functionally distinct population of long-term hematopoietic stem cells. Blood. 2008;111(4): 2444-2451. (Pubitemid 351451458)
19. Karlsson G, Rörby E, Pina C, et al. The tetraspanin CD9 affords high-purity capture of all murine hematopoietic stem cells. Cell Rep. 2013; 4(4):642-648.
20. Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med. 1996;183(4): 1797-1806. (Pubitemid 26134320)
21. Notta F, Doulatov S, Laurenti E, Poeppl A, Jurisica I, Dick JE. Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. Science. 2011; 333(6039):218-221.
22. Bryder D, Rossi DJ, Weissman IL. Hematopoietic stem cells: the paradigmatic tissue-specific stem cell. Am J Pathol. 2006;169(2):338-346. (Pubitemid 44156296)
23. Kobayashi M, Srour EF. Regulation of murine hematopoietic stem cell quiescence by Dmtf1. Blood. 2011;118(25):6562-6571.
24. Chua HL, Plett PA, Sampson CH, et al. Long-term hematopoietic stem cell damage in a murine model of the hematopoietic syndrome of the acute radiation syndrome. Health Phys. 2012;103(4): 356-366.
25. Wang Y, Schulte BA, LaRue AC, Ogawa M, Zhou D. Total body irradiation selectively induces murine hematopoietic stem cell senescence. Blood. 2006;107(1):358-366. (Pubitemid 43053564)
26. Lin KK, Rossi L, Boles NC, Hall BE, George TC, Goodell MA. CD8+ is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway. PLoS Biol. 2011;9(9):e1001148.
27. Danet GH, Lee HW, Luongo JL, Simon MC, Bonnet DA. Dissociation between stem cell phenotype and NOD/SCID repopulating activity in human peripheral blood CD34(+) cells after ex vivo expansion. Exp Hematol. 2001;29(12): 1465-1473. (Pubitemid 34007622)
28. Glimm H, Oh IH, Eaves CJ. Human hematopoietic stem cells stimulated to proliferate in vitro lose engraftment potential during their S/G(2)/M transit and do not reenter G(0). Blood. 2000;96(13): 4185-4193.
29. Beslu N, Krosl J, Laurin M, Mayotte N, Humphries KR, Sauvageau G. Molecular interactions involved in HOXB4-induced activation of HSC self-renewal. Blood. 2004;104(8):2307-2314. (Pubitemid 39331827)
30. Haug JS, He XC, Grindley JC, et al. N-cadherin expression level distinguishes reserved versus primed states of hematopoietic stem cells. Cell Stem Cell. 2008;2(4):367-379. (Pubitemid 351455240)
31. Hosokawa K, Arai F, Yoshihara H, et al. Knockdown of N-cadherin suppresses the longterm engraftment of hematopoietic stem cells. Blood. 2010;116(4):554-563.
32. Hergeth SP, Aicher WK, Essl M, Schreiber TD, Sasaki T, Klein G. Characterization and functional analysis of osteoblast-derived fibulins in the human hematopoietic stem cell niche. Exp Hematol. 2008;36(8):1022-1034.
33. Lunter PC, van Kilsdonk JW, van Beek H, et al. Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity. Cancer Res. 2005;65(19):8801-8808. (Pubitemid 41377368)
34. Welte T, Zhang SS, Wang T, et al. STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity. Proc Natl Acad Sci USA. 2003;100(4):1879-1884. (Pubitemid 36254542)
35. Mantel C, Messina-Graham S, Moh A, et al. Mouse hematopoietic cell-targeted STAT3 deletion: stem/progenitor cell defects, mitochondrial dysfunction, ROS overproduction, and a rapid aging-like phenotype. Blood. 2012; 120(13):2589-2599.
36. Barata JT, Boussiotis VA, Yunes JA, et al. IL-7-dependent human leukemia T-cell line as a valuable tool for drug discovery in T-ALL. Blood. 2004;103(5):1891-1900. (Pubitemid 38268988)
37. Abramovich C, Pineault N, Ohta H, Humphries RK. Hox genes: from leukemia to hematopoietic stem cell expansion. Ann N Y Acad Sci. 2005; 1044(1):109-116. (Pubitemid 40967600)
38. Kiel MJ, Radice GL, Morrison SJ. Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenance. Cell Stem Cell. 2007;1(2): 204-217. (Pubitemid 47215590)