CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway

PLoS Biology

Volumn 9, Issue 9, 2011, Pages

  Lin, Kuanyin K ^a,b   Rossi, Lara ^a,b,c   Boles, Nathan C ^a,b   Hall, Brian E ^d   George, Thaddeus C ^d   Goodell, Margaret A ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b CENTER FOR CELL AND GENE THERAPY   (United States)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d Amnis Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD48 ANTIGEN; CD81 ANTIGEN; CYCLIN D1; FLUOROURACIL; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 14; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE 1; TRANSCRIPTION FACTOR FKHR; CD81 PROTEIN, MOUSE; DRUG DERIVATIVE; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE; PERIFOSINE; PHOSPHORYLCHOLINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CYCLE PROGRESSION; CELL MEMBRANE; CELL NUCLEUS; CELL POPULATION; CELL PROLIFERATION; CELL RENEWAL; CELL STIMULATION; CELL STRESS; CONTROLLED STUDY; ENGRAFTMENT; ENVIRONMENTAL STRESS; ENZYME INACTIVATION; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; MOUSE; NONHUMAN; POLARIZATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; ANIMAL; C57BL MOUSE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOSUPPRESSIVE TREATMENT; METABOLISM; METHODOLOGY; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

MUS;

ANIMALS; ANTIGENS, CD81; CELL PROLIFERATION; ENZYME ACTIVATION; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASES; OXIDATIVE STRESS; PHOSPHORYLCHOLINE; PROTO-ONCOGENE PROTEINS C-AKT; TRANSPLANTATION CONDITIONING;

EID: 80053296176     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001148     Document Type: Article

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