Intoxication of host cells by the T3SS phospholipase ExoU: PI(4,5)P 2-associated, cytoskeletal collapse and late phase membrane blebbing

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Sato, Hiromi ^a   Frank, Dara W ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE; PHOSPHOLIPASE EXOU; PHOSPHOLIPID; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE A2; PSEUDOMONAS EXOPROTEIN A PROTEIN, PSEUDOMONAS AERUGINOSA; UBIQUITIN;

ACTIN DEPOLYMERIZATION; ARTICLE; BINDING AFFINITY; BLEB MEMBRANE; CELL DAMAGE; CELL DEATH; CELL MEMBRANE; CELL ROUNDING; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CONTROLLED STUDY; CYTOSKELETAL COLLAPSE; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; EPITHELIUM CELL; EUKARYOTIC CELL; FEMALE; FLUORESCENCE MICROSCOPY; FOCAL ADHESION; HELA CELL LINE; HOST CELL; HUMAN; HUMAN CELL; NONHUMAN; PLASMA MEMBRANE INTEGRITY; PROTEIN CLEAVAGE; PROTEIN HYDROLYSIS; PROTEIN LIPID INTERACTION; PSEUDOMONAS AERUGINOSA; CHEMISTRY; CYTOPLASM; CYTOSKELETON; ENZYMOLOGY; METABOLISM; MICROBIOLOGY; OPPORTUNISTIC INFECTION; PATHOGENICITY; PATHOLOGY; PSEUDOMONAS INFECTION;

BACTERIAL PROTEINS; CELL MEMBRANE; CYTOPLASM; CYTOSKELETON; HUMANS; OPPORTUNISTIC INFECTIONS; PHOSPHATIDYLINOSITOLS; PHOSPHOLIPASES A2; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; UBIQUITIN;

EID: 84904896550     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0103127     Document Type: Article

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