On the physiological roles of PIP2 at cardiac Na+- Ca2+ exchangers and KATP channels: A long journey from membrane biophysics into cell biology

Journal of Physiology

Volumn 582, Issue 3, 2007, Pages 903-909

  Hilgemann, Donald W ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATE; CALCIUM; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POTASSIUM CHANNEL; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CALCIUM ION; CALMODULIN; CELL PROTEIN; NCX1 PROTEIN; SODIUM CALCIUM EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

BIOPHYSICS; CELL BUDDING; CELL MEMBRANE; CONFERENCE PAPER; CYTOLOGY; ENDOCYTOSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART CONTRACTION; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE; HUMAN; INTERNALIZATION; LIPID ANALYSIS; LIPID METABOLISM; LIPOGENESIS; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; REGULATORY MECHANISM; SARCOLEMMA; SIGNAL TRANSDUCTION; ARTICLE; CONCENTRATION (PARAMETERS); CYTOPLASM; HEART MUSCLE METABOLISM; HORMONAL REGULATION; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS;

CELL LINE; CELL MEMBRANE; HEART; HUMANS; MEMBRANE POTENTIALS; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING;

EID: 34547110529     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2007.132746     Document Type: Conference Paper

References (34)

1. + exchange in cardiac sarcolemmal vesicles. Am J Physiol Cell Physiol 274, C724-C733.
2. Boucrot E, Saffarian S, Massol R, Kirchhausen T & Ehrlich M (2006). Role of lipids and actin in the formation of clathrin-coated pits. Exp Cell Res 312, 4036-4048.
3. Cho H, Kim YA, Yoon JY, Lee D, Kim JH, Lee SH & Ho WK (2005 a). Low mobility of phosphatidylinositol 4,5-bisphosphate underlies receptor specificity of Gq-mediated ion channel regulation in atrial myocytes. Proc Natl Acad Sci U S A 102, 15241-15246.
4. + channels in a receptor-specific manner. Proc Natl Acad Sci U S A 102, 4643-4648.
5. Doughman RL, Firestone AJ & Anderson RA (2003). Phosphatidylinositol phosphate kinases put PI4,5P2 in its place. J Membr Biol 194, 77-89.
6. 2 -binding proteins involved in signaling by tyrosine kinase. J Biol Chem 269, 1518-1522.
7. Giblin JP, Cui Y, Clapp LH & Tinker A (2002 a). Assembly limits the pharmacological complexity of ATP-sensitive potassium channels. J Biol Chem 277, 13717-13723.
8. Giblin JP, Quinn K & Tinker A (2002 b). The cytoplasmic C-terminus of the sulfonylurea receptor is important for KATP channel function but is not key for complex assembly or trafficking. Eur J Biochem 269, 5303-5313.
9. Gumina R, O'Cochlain DF, Kurtz C, Bast P, Pucar D, Mishra P, Miki T, Seino S, Macura S & Terzic A (2006). KATP channel knockout worsens myocardial calcium stress-load in vivo and impairs recovery in stunned heart. Am J Physiol Heart Circ Physiol 292, H1706-H1713.
10. + exchange: Cardiac-specific knockout of NCX1. Circ Res 95, 604-611.
11. 2. Science 273, 956-959.
12. + exchange current stimulation by MgATP: Possible involvement of aminophospholipid translocase. J Physiol 454, 59-82.
13. Hilgemann DW, Collins A & Matsuoka S (1992). Steady-state and dynamic properties of cardiac sodium-calcium exchange. Secondary modulation by cytoplasmic calcium and ATP. J Gen Physiol 100, 933-961.
14. Hilgemann DW, Feng S & Nasuhoglu C (2001). The complex and intriguing lives of PIP 2 with ion channels and transporters. Sci STKE 2001, RE19.
15. 2+ exchanger (NCX1, NCX2, NCX3). Am J Physiol Cell Physiol 274, C415-C423.
16. Massol RH, Boll W, Griffin AM & Kirchhausen T (2006). A burst of auxilin recruitment determines the onset of clathrin-coated vesicle uncoating. Proc Natl Acad Sci U S A 103, 10265-10270.
17. Morris JB, Huynh H, Vasilevski O & Woodcock EA (2006). α1-Adrenergic receptor signaling is localized to caveolae in neonatal rat cardiomyocytes. J Mol Cell Cardiol 41, 17-25.
18. 2 by cardioactive hormones and other physiologically relevant interventions. Am J Physiol Cell Physiol 283, C223-C234.
19. Nasuhoglu C, Feng S, Mao J, Yamamoto M, Yin HL, Earnest S, Barylko B, Albanesi JP & Hilgemann DW (2002a). Nonradioactive analysis of phosphatidylinositides and other anionic phospholipids by anion-exchange high-performance liquid chromatography with suppressed conductivity detection. Anal Biochem 301, 243-254.
20. Padron D, Wang YJ, Yamamoto M, Yin H & Roth MG (2003). Phosphatidylinositol phosphate 5-kinase Iβ recruits AP-2 to the plasma membrane and regulates rates of constitutive endocytosis. J Cell Biol 162, 693-701.
21. Perez-Mansilla B, Ha VL, Justin N, Wilkins AJ, Carpenter CL & Thomas GM (2006). The differential regulation of phosphatidylinositol 4-phosphate 5-kinases and phospholipase D1 by ADP-ribosylation factors 1 and 6. Biochim Biophys Acta 1761, 1429-1442.
22. 2+ flux. Circ Res 97, 1288-1295.
23. Reuter H, Han T, Motter C, Philipson KD & Goldhaber JI (2004). Mice overexpressing the cardiac sodium-calcium exchanger: Defects in excitation-contraction coupling. J Physiol 554, 779-789.
24. Riedel MJ, Baczko I, Searle GJ, Webster N, Fercho M, Jones L, Lang J, Lytton J, Dyck JR & Light PE (2006). Metabolic regulation of sodium-calcium exchange by intracellular acyl CoAs. EMBO J 25, 4605-4614.
25. Schulze D, Rapedius M, Krauter T & Baukrowitz T (2003). Long-chain acyl-CoA esters and phosphatidylinositol phosphates modulate ATP inhibition of KATP channels by the same mechanism. J Physiol 552, 357-367.
26. 2: analysis of the surface membrane fraction by extracellular cysteine PEGylation. J Physiol 582, 1011-1026.
27. 2 gate KCNQ ion channels. Science 314, 1454-1457.
28. Tong X, Porter LM, Liu G, Dhar-Chowdhury P, Srivastava S, Pountney DJ, Yoshida H, Artman M, Fishman GI, Yu C, Iyer R, Morley GE, Gutstein DE & Coetzee WA (2006). Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits. Am J Physiol Heart Circ Physiol 291, H543-H551.
29. Varnai P, Thyagarajan B, Rohacs T & Balla T (2006). Rapidly inducible changes in phosphatidylinositol 4,5-bisphosphate levels influence multiple regulatory functions of the lipid in intact living cells. J Cell Biol 175, 377-382.
30. 2+ signaling. J Cell Biol 167, 1005-1010.
31. Wang YJ, Wang J, Sun HQ, Martinez M, Sun YX, Macia E, Kirchhausen T, Albanesi JP, Roth MG & Yin HL (2003). Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi. Cell 114, 299-310.
32. Wei YJ, Sun HQ, Yamamoto M, Wlodarski P, Kunii K, Martinez M, Barylko B, Albanesi JP & Yin HL (2002). Type II phosphatidylinositol 4-kinase β is a cytosolic and peripheral membrane protein that is recruited to the plasma membrane and activated by Rac-GTP. J Biol Chem 277, 46586-46593.
33. Yaradanakul A, Feng S, Shen C, Lariccia V, Lin MJ, Kang TM, Yang J, Albanesi JP, Dong P & Hilgemann DW (2007). Dual control of cardiac Na/Ca exchange by PIP 2: Electrophysiological analysis of direct and indirect mechanisms. J Physiol 582, 991-1010.
34. Yin HL & Janmey PA (2003). Phosphoinositide regulation of the actin cytoskeleton. Annu Rev Physiol 65, 761-789.