VapC from the leptospiral VapBC toxin-antitoxin module displays ribonuclease activity on the initiator tRNA

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Lopes, Alexandre P Y ^a   Lopes, Luana M ^a   Fraga, Tatiana R ^a   Chura Chambi, Rosa M ^b   Sanson, André L ^a   Cheng, Elisabeth ^a   Nakajima, Erika ^a   Morganti, Ligia ^b   Martins, Elizabeth A L ^a  

^a INSTITUTO BUTANTAN   (Brazil)

^b INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM HYDROXIDE; ANTITOXIN; ANTITOXIN VAPB; ANTITOXIN VAPC; BACTERIAL TOXIN; IMMUNOLOGICAL ADJUVANT; RECOMBINANT PROTEIN; RIBONUCLEASE; TOXIN VAPB; TOXIN VAPC; TRANSFER RNA; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; DNA BINDING PROTEIN; MEMBRANE PROTEIN; METHIONINE TRANSFER RNA; VAPB PROTEIN, BACTERIA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIGEN ANTIBODY COMPLEX; ANTIGEN ANTIBODY REACTION; ARTICLE; BINDING AFFINITY; CELL INCLUSION; CIRCULAR DICHROISM; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ESCHERICHIA COLI; FEMALE; GROWTH INHIBITION; HYDROSTATIC PRESSURE; IMMUNIZATION; IN VITRO STUDY; IN VIVO STUDY; LEPTOSPIRA INTERROGANS; LIGAND BINDING; MOLECULAR CLONING; MOUSE; NONHUMAN; OPERON; POSTTRANSCRIPTIONAL GENE SILENCING; PROTEIN BLOTTING; PROTEIN CLEAVAGE; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; SHIGELLA; SPECIES COMPARISON; STRUCTURE ANALYSIS; TOXIN ANALYSIS; TOXIN STRUCTURE; TOXIN SYNTHESIS; VAPB GENE; VAPC GENE; X RAY SPECTROMETRY; AMINO ACID SEQUENCE; ANIMAL; BAGG ALBINO MOUSE; CHEMICAL STRUCTURE; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; PROTEIN REFOLDING;

AMINO ACID SEQUENCE; ANIMALS; ANTITOXINS; BACTERIAL PROTEINS; BACTERIAL TOXINS; CLONING, MOLECULAR; DNA-BINDING PROTEINS; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; LEPTOSPIRA INTERROGANS; MEMBRANE GLYCOPROTEINS; MICE, INBRED BALB C; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OPERON; PROTEIN REFOLDING; RECOMBINANT PROTEINS; RIBONUCLEASES; RNA, TRANSFER, MET;

EID: 84904680818     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0101678     Document Type: Article

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