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Volumn 9, Issue 7, 2014, Pages

Inhibitory action of benzo[α]pyrene on hepatic lipoprotein receptors in Vitro and on liver lipid homeostasis in mice

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; ABC TRANSPORTER G1; ACYL COENZYME A; ACYL COENZYME A CHOLESTEROL ACYLTRANSFERASE 1; ACYL COENZYME A CHOLESTEROL ACYLTRANSFERASE 2; BENZO[A]PYRENE; CHOLESTEROL ACYLTRANSFERASE; HIGH DENSITY LIPOPROTEIN; LACTACYSTIN; LIPOLYSIS STIMULATED LIPOPROTEIN RECEPTOR; LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; SCAVENGER RECEPTOR BI; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ANGULIN-1 PROTEIN, MOUSE; CHOLESTEROL;

EID: 84904678764     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102991     Document Type: Article
Times cited : (12)

References (59)
  • 1
    • 34547654219 scopus 로고    scopus 로고
    • The global epidemic of obesity: An overview
    • Caballero B (2007) The global epidemic of obesity: an overview. Epidemiol Rev 29: 1-5.
    • (2007) Epidemiol Rev , vol.29 , pp. 1-5
    • Caballero, B.1
  • 2
    • 77949556649 scopus 로고    scopus 로고
    • Where can I find obesity statistics?
    • Cunningham E (2010) Where can I find obesity statistics? J Am Diet Assoc 110: 656.
    • (2010) J Am Diet Assoc , vol.110 , pp. 656
    • Cunningham, E.1
  • 4
    • 80052156367 scopus 로고    scopus 로고
    • The complex metabolic mechanisms relating obesity to hypertriglyceridemia
    • Eckel RH (2011) The complex metabolic mechanisms relating obesity to hypertriglyceridemia. Arterioscler Thromb Vasc Biol 31: 1946-1948.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 1946-1948
    • Eckel, R.H.1
  • 5
    • 0022549920 scopus 로고
    • A receptor-mediated pathway for cholesterol homeostasis
    • Brown MS, Goldstein JL (1986) A receptor-mediated pathway for cholesterol homeostasis. Science 232: 34-47. (Pubitemid 16037973)
    • (1986) Science , vol.232 , Issue.4746 , pp. 34-47
    • Brown, M.S.1    Goldstein, J.L.2
  • 6
    • 65549093979 scopus 로고    scopus 로고
    • Liver-specific loss of lipolysis-stimulated lipoprotein receptor triggers systemic hyperlipidemia in mice
    • Narvekar P, Berriel Diaz M, Krones-Herzig A, Hardeland U, Strzoda D, et al. (2009) Liver-specific loss of lipolysis-stimulated lipoprotein receptor triggers systemic hyperlipidemia in mice. Diabetes 58: 1040-1049.
    • (2009) Diabetes , vol.58 , pp. 1040-1049
    • Narvekar, P.1    Berriel Diaz, M.2    Krones-Herzig, A.3    Hardeland, U.4    Strzoda, D.5
  • 7
    • 84870056469 scopus 로고    scopus 로고
    • Structure and function of the lipolysis stimulated lipoprotein receptor
    • D Ekinci, editor editors. Rijeka: InTech
    • Stenger C, Corbier C, Yen FT (2012) Structure and function of the lipolysis stimulated lipoprotein receptor. In: D Ekinci, editor editors. Chemical Biology. Rijeka: InTech. pp. 267-292.
    • (2012) Chemical Biology , pp. 267-292
    • Stenger, C.1    Corbier, C.2    Yen, F.T.3
  • 8
    • 54449093230 scopus 로고    scopus 로고
    • Lipolysis stimulated lipoprotein receptor: A novel molecular link between hyperlipidemia, weight gain, and atherosclerosis in mice
    • Yen FT, Roitel O, Bonnard L, Notet V, Pratte D, et al. (2008) Lipolysis stimulated lipoprotein receptor: a novel molecular link between hyperlipidemia, weight gain, and atherosclerosis in mice. J Biol Chem 283: 25650-25659.
    • (2008) J Biol Chem , vol.283 , pp. 25650-25659
    • Yen, F.T.1    Roitel, O.2    Bonnard, L.3    Notet, V.4    Pratte, D.5
  • 10
    • 78649878270 scopus 로고    scopus 로고
    • Up-regulation of hepatic lipolysis stimulated lipoprotein receptor by leptin: A potential lever for controlling lipid clearance during the postprandial phase
    • Stenger C, Hanse M, Pratte D, Mbala ML, Akbar S, et al. (2010) Up-regulation of hepatic lipolysis stimulated lipoprotein receptor by leptin: a potential lever for controlling lipid clearance during the postprandial phase. Faseb J 24: 4218-4228.
    • (2010) Faseb J , vol.24 , pp. 4218-4228
    • Stenger, C.1    Hanse, M.2    Pratte, D.3    Mbala, M.L.4    Akbar, S.5
  • 11
    • 67349125425 scopus 로고    scopus 로고
    • Role of nutrition and environmental endocrine disrupting chemicals during the perinatal period on the aetiology of obesity
    • Heindel JJ, vom Saal FS (2009) Role of nutrition and environmental endocrine disrupting chemicals during the perinatal period on the aetiology of obesity. Mol Cell Endocrinol 304: 90-96.
    • (2009) Mol Cell Endocrinol , vol.304 , pp. 90-96
    • Heindel, J.J.1    Vom Saal, F.S.2
  • 13
    • 84872385971 scopus 로고    scopus 로고
    • The endocrine disruptor mono-(2-ethylhexyl) phthalate promotes adipocyte differentiation and induces obesity in mice
    • Hao C, Cheng X, Xia H, Ma X (2012) The endocrine disruptor mono-(2-ethylhexyl) phthalate promotes adipocyte differentiation and induces obesity in mice. Biosci Rep 32: 619-629.
    • (2012) Biosci Rep , vol.32 , pp. 619-629
    • Hao, C.1    Cheng, X.2    Xia, H.3    Ma, X.4
  • 14
    • 77954104861 scopus 로고    scopus 로고
    • Environmental endocrine disruptors promote adipogenesis in the 3T3-L1 cell line through glucocorticoid receptor activation
    • Sargis RM, Johnson DN, Choudhury RA, Brady MJ (2010) Environmental endocrine disruptors promote adipogenesis in the 3T3-L1 cell line through glucocorticoid receptor activation. Obesity (Silver Spring) 18: 1283-1288.
    • (2010) Obesity (Silver Spring) , vol.18 , pp. 1283-1288
    • Sargis, R.M.1    Johnson, D.N.2    Choudhury, R.A.3    Brady, M.J.4
  • 16
    • 84865727515 scopus 로고    scopus 로고
    • Paternal benzo[α]pyrene exposure affects gene expression in the early developing mouse embryo
    • Brevik A, Lindeman B, Rusnakova V, Olsen AK, Brunborg G, et al. (2012) Paternal benzo[α]pyrene exposure affects gene expression in the early developing mouse embryo. Toxicol Sci 129: 157-165.
    • (2012) Toxicol Sci , vol.129 , pp. 157-165
    • Brevik, A.1    Lindeman, B.2    Rusnakova, V.3    Olsen, A.K.4    Brunborg, G.5
  • 18
    • 68949104869 scopus 로고    scopus 로고
    • Scientific opinion of the panel on contaminants in the food chain on a request from the European Commission on polycyclic aromatic hydrocarbons in food
    • EFSA
    • EFSA (2008) Scientific opinion of the panel on contaminants in the food chain on a request from the European Commission on polycyclic aromatic hydrocarbons in food. The EFSA Journal 724: 1-114.
    • (2008) The EFSA Journal , vol.724 , pp. 1-114
  • 19
    • 0021060205 scopus 로고
    • Factors affecting plasma benzo[a]pyrene levels in environmental studies
    • Hutcheon DE, Kantrowitz J, Van Gelder RN, Flynn E (1983) Factors affecting plasma benzo[α]pyrene levels in environmental studies. Environ Res 32: 104-110. (Pubitemid 14240601)
    • (1983) Environmental Research , vol.32 , Issue.1 , pp. 104-110
    • Hutcheon, D.E.1    Kantrowitz, J.2    Van Gelder, R.N.3    Flynn, E.4
  • 20
    • 33745158317 scopus 로고    scopus 로고
    • Benzo[a]pyrene impairs beta-adrenergic stimulation of adipose tissue lipolysis and causes weight gain in mice: A novel molecular mechanism of toxicity for a common food pollutant
    • DOI 10.1111/j.1742-4658.2006.05159.x
    • Irigaray P, Ogier V, Jacquenet S, Notet V, Sibille P, et al. (2006) Benzo[α]pyrene impairs beta-adrenergic stimulation of adipose tissue lipolysis and causes weight gain in mice. A novel molecular mechanism of toxicity for a common food pollutant. Febs J 273: 1362-1372. (Pubitemid 44029103)
    • (2006) FEBS Journal , vol.273 , Issue.7 , pp. 1362-1372
    • Irigaray, P.1    Ogier, V.2    Jacquenet, S.3    Notet, V.4    Sibille, P.5    Mejean, L.6    Bihain, B.E.7    Yen, F.T.8
  • 21
    • 0037219083 scopus 로고    scopus 로고
    • Analysis of DNA and protein adducts of benzo[a]pyrene in human tissues using structure-specific methods
    • DOI 10.1016/S1383-5742(02)00068-6, PII S1383574202000686
    • Boysen G, Hecht SS (2003) Analysis of DNA and protein adducts of benzo[α]pyrene in human tissues using structure-specific methods. Mutat Res 543: 17-30. (Pubitemid 36050911)
    • (2003) Mutation Research - Reviews in Mutation Research , vol.543 , Issue.1 , pp. 17-30
    • Boysen, G.1    Hecht, S.S.2
  • 22
    • 0019969562 scopus 로고
    • Interindividual variation in benzo(a)pyrene metabolism and composition of isoenzymes of cytochrome P-450 as revealed by SDS-gel electrophoresis of human liver microsomal fractions
    • Ekstrom G, von Bahr C, Glaumann H, Ingelman-Sundberg M (1982) Interindividual variation in benzo(a)pyrene metabolism and composition of isoenzymes of cytochrome P-450 as revealed by SDS-gel electrophoresis of human liver microsomal fractions. Acta Pharmacol Toxicol (Copenh) 50: 251-260. (Pubitemid 12074172)
    • (1982) Acta Pharmacologica et Toxicologica , vol.50 , Issue.4 , pp. 251-260
    • Ekstrom, G.1    Von Bahr, C.2    Glaumann, H.3    Ingelman-Sundberg, M.4
  • 23
    • 0023116884 scopus 로고
    • 1 mouse liver and lung
    • DOI 10.1016/0300-483X(87)90090-4
    • Mitchell CE, Fischer JP, Dahl AR (1987) Differential induction of cytochrome P-450 catalyzed activities by polychlorinated biphenyls and benzo [α]pyrene in B6C3F1 mouse liver and lung. Toxicology 43: 315-323. (Pubitemid 17024455)
    • (1987) Toxicology , vol.43 , Issue.3 , pp. 315-323
    • Mitchell, C.E.1    Fischer, J.P.2    Dahl, A.R.3
  • 24
    • 2442745398 scopus 로고
    • A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: Its possible translocation to nucleus
    • Fujisawa-Sehara A, Yamane M, Fujii-Kuriyama Y (1988) A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to nucleus. Proc Natl Acad Sci U S A 85: 5859-5863.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 5859-5863
    • Fujisawa-Sehara, A.1    Yamane, M.2    Fujii-Kuriyama, Y.3
  • 27
    • 0025306867 scopus 로고
    • Comparative uptake, vascular transport, and cellular internalization of aflatoxin-B1 and benzo(a)pyrene
    • DOI 10.1007/BF01972988
    • Busbee DL, Norman JO, Ziprin RL (1990) Comparative uptake, vascular transport, and cellular internalization of aflatoxin-B1 and benzo(a)pyrene. Arch Toxicol 64: 285-290. (Pubitemid 20185352)
    • (1990) Archives of Toxicology , vol.64 , Issue.4 , pp. 285-290
    • Busbee, D.L.1    Norman, J.O.2    Ziprin, R.L.3
  • 28
    • 0019179954 scopus 로고
    • Serum and tissue distribution of benzo[a]pyrene from intravenously injected chylomicrons in rat in vivo
    • DOI 10.1016/0304-3835(80)90101-9
    • Vauhkonen M, Kuusi T, Kinnunen PK (1980) Serum and tissue distribution of benzol[α]pyrene from intravenously injected chylomicrons in rat in vivo. Cancer Lett 11: 113-119. (Pubitemid 11179861)
    • (1980) Cancer Letters , vol.11 , Issue.2 , pp. 113-119
    • Vauhkonen, M.1    Kuusi, T.2    Kinnunen, K.J.3
  • 30
    • 84871212796 scopus 로고    scopus 로고
    • Exposure of primary porcine urothelial cells to benzo(a)pyrene: In vitro uptake, intracellular concentration, and biological response
    • Verma N, Pink M, Petrat F, Rettenmeier AW, Schmitz-Spanke S (2012) Exposure of primary porcine urothelial cells to benzo(a)pyrene: in vitro uptake, intracellular concentration, and biological response. Arch Toxicol 86: 1861-1871.
    • (2012) Arch Toxicol , vol.86 , pp. 1861-1871
    • Verma, N.1    Pink, M.2    Petrat, F.3    Rettenmeier, A.W.4    Schmitz-Spanke, S.5
  • 32
    • 33749488939 scopus 로고    scopus 로고
    • Human multidrug resistance ABCB and ABCG transporters: Participation in a chemoimmunity defense system
    • DOI 10.1152/physrev.00037.2005
    • Sarkadi B, Homolya L, Szakacs G, Varadi A (2006) Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system. Physiol Rev 86: 1179-1236. (Pubitemid 44521651)
    • (2006) Physiological Reviews , vol.86 , Issue.4 , pp. 1179-1236
    • Sarkadi, B.1    Homolya, L.2    Szakacs, G.3    Varadi, A.4
  • 33
    • 84945732206 scopus 로고
    • The MTT tetrazolium salt assay scrutinized: How to use this assay reliably to measure metabolic activity of cell cultures in vitro for the assessment of growth characteristics, IC50-values and cell survival
    • Sieuwerts AM, Klijn JG, Peters HA, Foekens JA (1995) The MTT tetrazolium salt assay scrutinized: how to use this assay reliably to measure metabolic activity of cell cultures in vitro for the assessment of growth characteristics, IC50-values and cell survival. Eur J Clin Chem Clin Biochem 33: 813-823.
    • (1995) Eur J Clin Chem Clin Biochem , vol.33 , pp. 813-823
    • Sieuwerts, A.M.1    Klijn, J.G.2    Peters, H.A.3    Foekens, J.A.4
  • 34
    • 20944442355 scopus 로고    scopus 로고
    • Novel fluorescence assay using calcein-AM for the determination of human erythrocyte viability and aging
    • DOI 10.1002/cyto.a.20152
    • Bratosin D, Mitrofan L, Palii C, Estaquier J, Montreuil J (2005) Novel fluorescence assay using calcein-AM for the determination of human erythrocyte viability and aging. Cytometry A 66: 78-84. (Pubitemid 40868922)
    • (2005) Cytometry Part A , vol.66 , Issue.1 , pp. 78-84
    • Bratosin, D.1    Mitrofan, L.2    Palii, C.3    Estaquier, J.4    Montreuil, J.5
  • 35
    • 0029088393 scopus 로고
    • Mechanism of activation and functional significance of the lipolysis-stimulated receptor. Evidence for a role as chylomicron remnant receptor
    • Mann CJ, Khallou J, Chevreuil O, Troussard AA, Guermani LM, et al. (1995) Mechanism of activation and functional significance of the lipolysis-stimulated receptor. Evidence for a role as chylomicron remnant receptor. Biochemistry 34: 10421-10431.
    • (1995) Biochemistry , vol.34 , pp. 10421-10431
    • Mann, C.J.1    Khallou, J.2    Chevreuil, O.3    Troussard, A.A.4    Guermani, L.M.5
  • 36
    • 84870066456 scopus 로고    scopus 로고
    • Lactoferrin and its hydrolysate bind directly to the oleate-activated form of the lipolysis stimulated lipoprotein receptor
    • Ahmad N, Girardet JM, Akbar S, Lanhers MC, Paris C, et al. (2012) Lactoferrin and its hydrolysate bind directly to the oleate-activated form of the lipolysis stimulated lipoprotein receptor. Febs J 279: 4361-4373.
    • (2012) Febs J , vol.279 , pp. 4361-4373
    • Ahmad, N.1    Girardet, J.M.2    Akbar, S.3    Lanhers, M.C.4    Paris, C.5
  • 38
    • 84882658057 scopus 로고    scopus 로고
    • Neurobehavioral toxicity of a repeated exposure (14 days) to the airborne polycyclic aromatic hydrocarbon fluorene in adult Wistar male rats
    • Peiffer J, Cosnier F, Grova N, Nunge H, Salquèbre G, et al. (2013) Neurobehavioral toxicity of a repeated exposure (14 days) to the airborne polycyclic aromatic hydrocarbon fluorene in adult Wistar male rats. PLoS One 8: e71413.
    • (2013) PLoS One , vol.8
    • Peiffer, J.1    Cosnier, F.2    Grova, N.3    Nunge, H.4    Salquèbre, G.5
  • 39
    • 80054765920 scopus 로고    scopus 로고
    • Determination of PAHs and OH-PAHs in rat brain by gas chromatography tandem (triple quadrupole) mass spectrometry
    • Grova N, Salquèbre G, Schroeder H, Appenzeller BM (2011) Determination of PAHs and OH-PAHs in rat brain by gas chromatography tandem (triple quadrupole) mass spectrometry. Chem Res Toxicol 24: 1653-1667.
    • (2011) Chem Res Toxicol , vol.24 , pp. 1653-1667
    • Grova, N.1    Salquèbre, G.2    Schroeder, H.3    Appenzeller, B.M.4
  • 40
    • 0033532198 scopus 로고    scopus 로고
    • Molecular cloning of a lipolysis-stimulated remnant receptor expressed in the liver
    • Yen FT, Masson M, Clossais-Besnard N, Andre P, Grosset JM, et al. (1999) Molecular cloning of a lipolysis-stimulated remnant receptor expressed in the liver. J Biol Chem 274: 13390-13398.
    • (1999) J Biol Chem , vol.274 , pp. 13390-13398
    • Yen, F.T.1    Masson, M.2    Clossais-Besnard, N.3    Andre, P.4    Grosset, J.M.5
  • 41
    • 0026751532 scopus 로고
    • Free fatty acids activate a high-affinity saturable pathway for degradation of low-density lipoproteins in fibroblasts from a subject homozygous for familial hypercholesterolemia
    • Bihain BE, Yen FT (1992) Free fatty acids activate a high-affinity saturable pathway for degradation of low-density lipoproteins in fibroblasts from a subject homozygous for familial hypercholesterolemia. Biochemistry 31: 4628-4636.
    • (1992) Biochemistry , vol.31 , pp. 4628-4636
    • Bihain, B.E.1    Yen, F.T.2
  • 42
    • 0024412961 scopus 로고
    • Unesterified fatty acids inhibit the binding of low density lipoproteins to the human fibroblast low density lipoprotein receptor
    • Bihain BE, Deckelbaum RJ, Yen FT, Gleeson AM, Carpentier YA, et al. (1989) Unesterified fatty acids inhibit the binding of low density lipoproteins to the human fibroblast low density lipoprotein receptor. J Biol Chem 264: 17316-17321. (Pubitemid 19255562)
    • (1989) Journal of Biological Chemistry , vol.264 , Issue.29 , pp. 17316-17321
    • Bihain, B.E.1    Deckelbaum, R.J.2    Yen, F.T.3    Gleeson, A.M.4    Carpentier, Y.A.5    Witte, L.D.6
  • 43
    • 84877961422 scopus 로고    scopus 로고
    • Identification of stable benzo[α]pyrene-7,8-dione-DNA adducts in human lung cells
    • Huang M, Blair IA, Penning TM (2013) Identification of stable benzo[α]pyrene-7,8-dione-DNA adducts in human lung cells. Chem Res Toxicol 26: 685-692.
    • (2013) Chem Res Toxicol , vol.26 , pp. 685-692
    • Huang, M.1    Blair, I.A.2    Penning, T.M.3
  • 44
    • 0022447889 scopus 로고
    • Benzo(a)pyrene:DNA adduct formation in normal human mammary epithelial cell cultures and the human mammary carcinoma T47D cell line
    • Pruess-Schwartz D, Baird WM, Nikbakht A, Merrick BA, Selkirk JK (1986) Benzo(a)pyrene:DNA adduct formation in normal human mammary epithelial cell cultures and the human mammary carcinoma T47D cell line. Cancer Res 46: 2697-2702. (Pubitemid 16074265)
    • (1986) Cancer Research , vol.46 , Issue.6 , pp. 2697-2702
    • Pruess-Schwartz, D.1    Baird, W.M.2    Nikbakht, A.3
  • 45
    • 0035116312 scopus 로고    scopus 로고
    • Inhibitory effects of RRR-alpha-tocopheryl succinate on benzo (a) pyrene (B (a) P )-induced forestomach carcinogenesis in female mice
    • Wu K, Shan YJ, Zhao Y, Yu JW, Liu BH (2001) Inhibitory effects of RRR-alpha-tocopheryl succinate on benzo(a)pyrene (B(a)P)-induced forestomach carcinogenesis in female mice. World J Gastroenterol 7: 60-65. (Pubitemid 32170899)
    • (2001) World Journal of Gastroenterology , vol.7 , Issue.1 , pp. 60-65
    • Wu, K.1    Shan, Y.J.2    Zhao, Y.3    Yu, J.W.4    Liu, B.H.5
  • 46
    • 77953476095 scopus 로고    scopus 로고
    • Cumulative exposure assessment for trace-level polycyclic aromatic hydrocarbons (PAHs) using human blood and plasma analysis
    • Pleil JD, Stiegel MA, Sobus JR, Tabucchi S, Ghio AJ, et al. (2010) Cumulative exposure assessment for trace-level polycyclic aromatic hydrocarbons (PAHs) using human blood and plasma analysis. J Chromatogr B Analyt Technol Biomed Life Sci 878: 1753-1760.
    • (2010) J Chromatogr B Analyt Technol Biomed Life Sci , vol.878 , pp. 1753-1760
    • Pleil, J.D.1    Stiegel, M.A.2    Sobus, J.R.3    Tabucchi, S.4    Ghio, A.J.5
  • 47
    • 84856968496 scopus 로고    scopus 로고
    • Excretion kinetics of urinary 3-hydroxybenzo[α]pyrene following dietary exposure to benzo[α]pyrene in humans
    • Chien YC, Yeh CT (2012) Excretion kinetics of urinary 3-hydroxybenzo[α]pyrene following dietary exposure to benzo[α]pyrene in humans. Arch Toxicol 86: 45-53.
    • (2012) Arch Toxicol , vol.86 , pp. 45-53
    • Chien, Y.C.1    Yeh, C.T.2
  • 50
    • 80052147737 scopus 로고    scopus 로고
    • Proteasomal inhibition promotes ATP-binding cassette transporter A1 (ABCA1) and ABCG1 expression and cholesterol efflux from macrophages in vitro and in vivo
    • Ogura M, Ayaori M, Terao Y, Hisada T, Iizuka M, et al. (2011) Proteasomal inhibition promotes ATP-binding cassette transporter A1 (ABCA1) and ABCG1 expression and cholesterol efflux from macrophages in vitro and in vivo. Arterioscler Thromb Vasc Biol 31: 1980-1987.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 1980-1987
    • Ogura, M.1    Ayaori, M.2    Terao, Y.3    Hisada, T.4    Iizuka, M.5
  • 51
    • 82355191522 scopus 로고    scopus 로고
    • Role of ubiquitination in PCSK9-mediated low-density lipoprotein receptor degradation
    • Chen Y, Wang H, Yu L, Yu X, Qian YW, et al. (2011) Role of ubiquitination in PCSK9-mediated low-density lipoprotein receptor degradation. Biochem Biophys Res Commun 415: 515-518.
    • (2011) Biochem Biophys Res Commun , vol.415 , pp. 515-518
    • Chen, Y.1    Wang, H.2    Yu, L.3    Yu, X.4    Qian, Y.W.5
  • 52
    • 84864851760 scopus 로고    scopus 로고
    • Molecular characterization of proprotein convertase subtilisin/kexin type 9-mediated degradation of the LDLR
    • Wang Y, Huang Y, Hobbs HH, Cohen JC (2012) Molecular characterization of proprotein convertase subtilisin/kexin type 9-mediated degradation of the LDLR. J Lipid Res 53: 1932-1943.
    • (2012) J Lipid Res , vol.53 , pp. 1932-1943
    • Wang, Y.1    Huang, Y.2    Hobbs, H.H.3    Cohen, J.C.4
  • 54
    • 0030198353 scopus 로고    scopus 로고
    • Binding and transport of benzo[a]pyrene by blood plasma lipoproteins: The possible role of apolipoprotein B in this process
    • DOI 10.1021/bc960005e
    • Polyakov LM, Chasovskikh MI, Panin LE (1996) Binding and transport of benzo[α]pyrene by blood plasma lipoproteins: the possible role of apolipoprotein B in this process. Bioconjug Chem 7: 396-400. (Pubitemid 26312129)
    • (1996) Bioconjugate Chemistry , vol.7 , Issue.4 , pp. 396-400
    • Polyakov, L.M.1    Chasovskikh, M.I.2    Panin, L.E.3
  • 55
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • DOI 10.1016/S0092-8674(00)80213-5
    • Brown MS, Goldstein JL (1997) The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89: 331-340. (Pubitemid 27220877)
    • (1997) Cell , vol.89 , Issue.3 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 56
    • 0030069736 scopus 로고    scopus 로고
    • Relative roles of the LDL receptor, the LDL receptor-like protein, and hepatic lipase in chylomicron remnant removal by the liver
    • de Faria E, Fong LG, Komaromy M, Cooper AD (1996) Relative roles of the LDL receptor, the LDL receptor-like protein, and hepatic lipase in chylomicron remnant removal by the liver. J Lipid Res 37: 197-209. (Pubitemid 26052631)
    • (1996) Journal of Lipid Research , vol.37 , Issue.1 , pp. 197-209
    • De Faria, E.1    Fong, L.G.2    Komaromy, M.3    Cooper, A.D.4
  • 57
    • 0029808272 scopus 로고    scopus 로고
    • Role of the low density lipoprotein (LDL) receptor pathway in the metabolism of chylomicron remnants. A quantitative study in knockout mice lacking the LDL receptor, apolipoprotein E, or both
    • DOI 10.1074/jbc.271.37.22422
    • Ishibashi S, Perrey S, Chen Z, Osuga J, Shimada M, et al. (1996) Role of the low density lipoprotein (LDL) receptor pathway in the metabolism of chylomicron remnants. A quantitative study in knockout mice lacking the LDL receptor, apolipoprotein E, or both. J Biol Chem 271: 22422-22427. (Pubitemid 26304676)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.37 , pp. 22422-22427
    • Ishibashi, S.1    Perrey, S.2    Chen, Z.3    Osuga, J.-I.4    Shimada, M.5    Ohashi, K.6    Harada, K.7    Yazaki, Y.8    Yamada, N.9
  • 58
    • 27144483358 scopus 로고    scopus 로고
    • Identification of BCRP as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists
    • DOI 10.1093/carcin/bgi139
    • Ebert B, Seidel A, Lampen A (2005) Identification of BCRP as transporter of benzo[α]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists. Carcinogenesis 26: 1754-1763. (Pubitemid 41487991)
    • (2005) Carcinogenesis , vol.26 , Issue.10 , pp. 1754-1763
    • Ebert, B.1    Seidel, A.2    Lampen, A.3
  • 59
    • 77954659321 scopus 로고    scopus 로고
    • Suppression of ABCA1 by unsaturated fatty acids leads to lipid accumulation in HepG2 cells
    • Yang Y, Jiang Y, Wang Y, An W (2010) Suppression of ABCA1 by unsaturated fatty acids leads to lipid accumulation in HepG2 cells. Biochimie 92: 958-963.
    • (2010) Biochimie , vol.92 , pp. 958-963
    • Yang, Y.1    Jiang, Y.2    Wang, Y.3    An, W.4


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