Impact of structural and metabolic variations on the toxicity and carcinogenicity of hydroxy- and alkoxy-substituted allyl- and propenylbenzenes

Chemical Research in Toxicology

Volumn 27, Issue 7, 2014, Pages 1092-1103

  Rietjens, I M C M ^a   Cohen, S M ^b   Fukushima, S ^c   Gooderham, N J ^d   Hecht, S ^e   Marnett, L J ^f   Smith, R L ^d   Adams, T B ^c   Bastaki, M ^c   Harman, C G ^c   Taylor, S V ^c  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c Japan Bioassay Research Center ^*  (United States)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF MINNESOTA   (United States)

^f VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLYL COMPOUND; ANETHOLE; BENZENE DERIVATIVE; CHAVICOL; ESTRAGOLE; EUGENOL; ISOCHAVICOL; ISOEUGENOL; METHYLEUGENOL; METHYLISOEUGENOL; PHENOL DERIVATIVE; SAFROLE; UNCLASSIFIED DRUG; CARCINOGEN;

ALKYLATION; CARCINOGENICITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; HYDROXYLATION; IN VITRO STUDY; METABOLIC ACTIVATION; METABOLISM; REVIEW; RISK ASSESSMENT; ANIMAL; BIOTRANSFORMATION; CHEMISTRY;

ANIMALS; BENZENE DERIVATIVES; BIOTRANSFORMATION; CARCINOGENS; HUMANS;

EID: 84904641005     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx500109s     Document Type: Review

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