Basil extract inhibits the sulfotransferase mediated formation of DNA adducts of the procarcinogen 1′-hydroxyestragole by rat and human liver S9 homogenates and in HepG2 human hepatoma cells

Food and Chemical Toxicology

Volumn 46, Issue 6, 2008, Pages 2296-2302

  Jeurissen, Suzanne M F ^a   Punt, Ans ^a,b   Delatour, Thierry ^b   Rietjens, Ivonne M C M ^a,c  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b NESTLÉ RESEARCH CENTER   (Switzerland)

^c TNO   (Netherlands)

Author keywords

Alkenylbenzenes; DNA adducts; Estragole; Ocimum basilicum; Sulfotransferases

Indexed keywords

1' HYDROXYESTRAGOLE; BASIL EXTRACT; CYTOCHROME P450; DEOXYGUANOSINE; DNA; ESTRAGOLE; PLANT EXTRACT; SULFOTRANSFERASE;

ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG INHIBITION; HEPATOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; NONHUMAN; RAT; RISK FACTOR; SULFATION;

ANIMALS; ANISOLES; BIOTRANSFORMATION; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA ADDUCTS; DNA REPAIR; ENZYME INHIBITORS; HUMANS; LIVER; LIVER NEOPLASMS; OCIMUM BASILICUM; PLANT EXTRACTS; RATS; RISK ASSESSMENT; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUBCELLULAR FRACTIONS; SULFOTRANSFERASES; TETRAZOLIUM SALTS; THIAZOLES;

OCIMUM; OCIMUM BASILICUM; RATTUS;

EID: 42749087687     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.03.010     Document Type: Article

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