Human cytochrome P450 enzyme specificity for the bioactivation of estragole and related alkenylbenzenes

Chemical Research in Toxicology

Volumn 20, Issue 5, 2007, Pages 798-806

  Jeurissen, Suzanne M F ^a   Punt, Ans ^a,b   Boersma, Marelle G ^a   Bogaards, Jan J P ^c   Fiamegos, Yiannis C ^a,d   Schilter, Benoit ^b   Van Bladeren, Peter J ^b   Cnubben, Nicole H P ^c   Rietjens, Ivonne M C M ^a,c  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b NESTLÉ RESEARCH CENTER   (Switzerland)

^c TNO   (Netherlands)

^d UNIVERSITY OF IOANNINA   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

1' HYDROXYESTRAGOLE; ALKENYLBENZENE DERIVATIVE; ALPHA NAPHTHOFLAVONE; BENZENE DERIVATIVE; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; CYTOCHROME P450 2C19; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; ESTRAGOLE; METHYLEUGENOL; SAFROLE; UNCLASSIFIED DRUG;

ARTICLE; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; HYDROXYLATION; LIVER MICROSOME; PHENOTYPE; PROTEIN EXPRESSION;

ANISOLES; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; EUGENOL; FLAVORING AGENTS; HUMANS; HYDROXYLATION; MICROSOMES, LIVER; SAFROLE; SUBSTRATE SPECIFICITY;

EID: 34250732298     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx700012d     Document Type: Article

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