Combinatorial therapy with acetylation and methylation modifiers attenuates lung vascular hyperpermeability in endotoxemia-induced mouse inflammatory lung injury

American Journal of Pathology

Volumn 184, Issue 8, 2014, Pages 2237-2249

  Thangavel, Jayakumar ^a   Malik, Asrar B ^b   Elias, Harold K ^a   Rajasingh, Sheeja ^a   Simpson, Andrew D ^a   Sundivakkam, Premanand K ^b   Vogel, Stephen M ^b   Xuan, Yu Ting ^a   Dawn, Buddhadeb ^a   Rajasingh, Johnson ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CASPASE 3; CAVEOLIN 1; DNA METHYLTRANSFERASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HISTONE; HISTONE DEACETYLASE; LIPOPOLYSACCHARIDE; MYELOPEROXIDASE; MYOSIN LIGHT CHAIN 2; TRICHOSTATIN A; VASCULAR ENDOTHELIAL CADHERIN; AZACITIDINE; DECITABINE; ENZYME INHIBITOR; HYDROXAMIC ACID;

ACETYLATION; ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENDOTOXEMIA; ENZYME ACTIVITY; ENZYME INHIBITION; EPIGENETICS; GENE EXPRESSION; LUNG ENDOTHELIUM; MALE; METHYLATION; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CAPILLARY PERMEABILITY; CHROMATIN IMMUNOPRECIPITATION; DISEASE MODEL; DRUG COMBINATION; DRUG EFFECTS; ENZYMOLOGY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; INFLAMMATION; LUNG; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TUNEL ASSAY; WESTERN BLOTTING;

ACETYLATION; ACUTE LUNG INJURY; ANIMALS; AZACITIDINE; BLOTTING, WESTERN; CAPILLARY PERMEABILITY; CELL PROLIFERATION; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; ENDOTHELIAL CELLS; ENDOTOXEMIA; ENZYME INHIBITORS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HYDROXAMIC ACIDS; IN SITU NICK-END LABELING; INFLAMMATION; LUNG; MALE; METHYLATION; MICE; MICE, INBRED C57BL; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84904635677     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2014.05.008     Document Type: Article

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