UPLC-MS/MS method for quantification of the azathioprine metabolites 6-mercaptoguanosine and 6-methylmercaptopurine riboside in peripheral blood mononuclear cells

Journal of Pharmaceutical and Biomedical Analysis

Volumn 98, Issue , 2014, Pages 271-278

  De Nicolò, Amedeo ^a   Agnesod, Danilo ^a   Simiele, Marco ^a   Riganò, Danila ^b   Adriani, Alessandro ^a   Canaparo, Roberto ^b   Astegiano, Marco ^a   Rizzetto, Mario ^a   Di Perri, Giovanni ^a   D'Avolio, Antonio ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

Intracellular determination; Nucleosides; Tandem mass detector; UPLC

Indexed keywords

6 METHYLTHIOINOSINE; ACETONITRILE; ACID PHOSPHATASE; AZATHIOPRINE; THIOGUANOSINE; 6-THIOGUANOSINE; GUANOSINE; NUCLEOSIDE;

ARTICLE; CALIBRATION; CLINICAL ARTICLE; DENSITY GRADIENT; DRUG METABOLISM; DRUG PENETRATION; DRUG STABILITY; HUMAN; INFLAMMATORY BOWEL DISEASE; METABOLITE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRECIPITATION; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANALOGS AND DERIVATIVES; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFLAMMATORY BOWEL DISEASES; MONONUCLEAR CELL; PROCEDURES;

AZATHIOPRINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GUANOSINE; HUMANS; INFLAMMATORY BOWEL DISEASES; LEUKOCYTES, MONONUCLEAR; METHYLTHIOINOSINE; TANDEM MASS SPECTROMETRY; THIONUCLEOSIDES;

EID: 84904615116     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2014.05.040     Document Type: Article

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