Development and validation of a useful HPLC-UV method for quantification of total and phosphorylated-ribavirin in blood and erythrocytes of HCV+ patients

Journal of Pharmaceutical and Biomedical Analysis

Volumn 66, Issue , 2012, Pages 376-380

  D'Avolio, Antonio ^a   De Nicolò, Amedeo ^a   Simiele, Marco ^a   Turini, Stefano ^a   Agnesod, Danilo ^a   Boglione, Lucio ^a   Cusato, Jessica ^a   Baietto, Lorena ^a   Cariti, Giuseppe ^a   Calcagno, Andrea ^a   Sciandra, Mauro ^a   Di Perri, Giovanni ^a   Bonora, Stefano ^a  

^a AMEDEO DI SAVOIA HOSPITAL   (Italy)

Author keywords

Anemia; HCV; HPLC UV; Intracellular; Ribavirin

Indexed keywords

ACETONITRILE; ACID PHOSPHATASE; ALPHA INTERFERON; DRUG METABOLITE; RIBAVIRIN;

ACCURACY; ARTICLE; CALIBRATION; CLINICAL ARTICLE; DIGESTION; DILUTION; DRUG BLOOD LEVEL; DRUG MONITORING; ERYTHROCYTE; HEPATITIS C; HUMAN; LIMIT OF DETECTION; LIMIT OF QUANTITATION; PHOSPHORYLATION; PRECIPITATION; PRIORITY JOURNAL; QUALITY CONTROL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY AND SENSIBILITY; ULTRAVIOLET RADIATION;

ANEMIA, HEMOLYTIC; ANTIVIRAL AGENTS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG MONITORING; ERYTHROCYTES; FEASIBILITY STUDIES; HEPATITIS C; HUMANS; INTERFERON-ALPHA; PHOSPHORYLATION; QUALITY CONTROL; RECOMBINANT PROTEINS; RIBAVIRIN;

EID: 84861220826     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.03.030     Document Type: Article

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