Engineering of cyanobacteria for the photosynthetic production of limonene from CO2

Journal of Biotechnology

Volumn 185, Issue , 2014, Pages 1-7

  Kiyota, Hiroshi ^a,b   Okuda, Yukiko ^a   Ito, Michiho ^c   Hirai, Masami Yokota ^b   Ikeuchi, Masahiko ^a,d  

^a UNIVERSITY OF TOKYO   (Japan)

^b RIKEN Center for Sustainable Resource Science   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Isoprenoid; Limonene; MEP pathway; Synechocystis; Synthetic biology

Indexed keywords

CARBON DIOXIDE; LIPIDS; PLANTS (BOTANY);

ISOPRENOIDS; LIMONENE; MEP PATHWAYS; SYNECHOCYSTIS; SYNTHETIC BIOLOGY;

MONOTERPENES;

CARBON DIOXIDE; DEOXYXYLULOSE 1 PHOSPHATE SYNTHASE; GERANYL PYROPHOSPHATE SYNTHASE; ISOPENTENYL DIPHOSPHATE DELTA ISOMERASE; LIMONENE; LIMONENE SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG; 2-C-METHYLERYTHRITOL 4-PHOSPHATE; CYCLOHEXENE DERIVATIVE; ERYTHRITOL; GERANYL PYROPHOSPHATE; ISOMERASE; ISOPRENOID PHOSPHATE; PINENE CYCLASE I; SUGAR PHOSPHATE; TERPENE;

ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CHEMICAL PROCEDURES; CONTROLLED STUDY; GAS STRIPPING METHOD; GENE OVEREXPRESSION; GENETIC ENGINEERING; HERB; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOTOSYNTHESIS; PRECURSOR; PRIORITY JOURNAL; SCHIZONEPETA TENUIFOLIA; SYNECHOCYSTIS; ANALOGS AND DERIVATIVES; BIOSYNTHESIS; CHEMISTRY; DNA SEQUENCE; ENZYMOLOGY; GENETICS; LAMIACEAE; MASS FRAGMENTOGRAPHY; METABOLISM; PHYSIOLOGY; PLASMID; PROCEDURES; WESTERN BLOTTING;

BIOSYNTHETIC PATHWAYS; BLOTTING, WESTERN; CARBON DIOXIDE; CYCLOHEXENES; ERYTHRITOL; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GENETIC ENGINEERING; INTRAMOLECULAR LYASES; LAMIACEAE; PHOTOSYNTHESIS; PLASMIDS; POLYISOPRENYL PHOSPHATES; SEQUENCE ANALYSIS, DNA; SUGAR PHOSPHATES; SYNECHOCYSTIS; TERPENES;

EID: 84904599448     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2014.05.025     Document Type: Article

References (39)

1. Aggarwal K.K., Khanuja S.P.S., Ahmad A., Santha Kumar T.R., Gupta V.K., Kumar S. Antimicrobial activity profiles of the two enantiomers of limonene and carvone isolated from the oils of Mentha spicata and Anethum sowa. Flavour Fragr. J. 2002, 17:59-63.
2. Agger S.A., Lopez-Gallego F., Hoye T.R., Schmidt-Dannert C. Identification of sesquiterpene synthases from Nostoc punctiforme PCC 73102 and Nostoc sp. strain PCC 7120. J. Bacteriol. 2008, 190:6084-6096.
3. Ajikumar P.K., Xiao W.H., Tyo K.E., Wang Y., Simeon F., Leonard E., Mucha O., Phon T.H., Pfeifer B., Stephanopoulos G. Isoprenoid pathway optimization for taxol precursor overproduction in Escherichia coli. Science 2010, 330:70-74.
4. Atsumi S., Higashide W., Liao J.C. Direct photosynthetic recycling of carbon dioxide to isobutyraldehyde. Nat. Biotechnol. 2009, 27:1177-1180.
5. Bentley F.K., Melis A. Diffusion-based process for carbon dioxide uptake and isoprene emission in gaseous/aqueous two-phase photobioreactors by photosynthetic microorganisms. Biotechnol. Bioeng. 2012, 109:100-109.
6. Bohlmann J., Keeling C.I. Terpenoid biomaterials. Plant J. 2008, 54:656-669.
7. Carter O.A., Peters R.J., Croteau R. Monoterpene biosynthesis pathway construction in Escherichia coli. Phytochemistry 2003, 64:425-433.
8. Chambon C., Ladeveze V., Oulmouden A., Servouse M., Karst E. Isolation and properties of yeast mutants affected in farnesyl diphosphate synthetase. Curr. Genet. 1990, 18:41-46.
9. Cunningham F.X., Lafond T.P., Gantt E. Evidence of a role for LytB in the nonmevalonate pathway of isoprenoid biosynthesis. J. Bacteriol. 2000, 182:5841-5848.
10. Curran K.A., Alper H.S. Expanding the chemical palate of cells by combining systems biology and metabolic engineering. Metab. Eng. 2012, 14:289-297.
11. Fernandez-Gonzalez B., Martnez-Ferez I.M., Vioque A. Characterization of two carotenoid gene promoters in the cyanobacterium Synechocystis sp. PCC 6803. Biochim. Biophys. Acta 1998, 1443:343-351.
12. Fornari T., Vicente G., Vazquez E., Garcia-Risco M.R., Reglero G. Isolation of essential oil from different plants and herbs by supercritical fluid extraction. J. Chromatogr. A 2012, 1250:34-48.
13. Ghayee H.K., Auchus R.J. Basic concepts and recent developments in human steroid hormone biosynthesis. Rev. Endocr. Metab. Disord. 2007, 8:289-300.
14. Harker M., Bramley P.M. Expression of prokaryotic 1-deoxy-d-xylulose-5-phosphatases in Escherichia coli increases carotenoid and ubiquinone biosynthesis. FEBS Lett. 1999, 448:115-119.
15. Ishizuka T., Shimada T., Okajima K., Yoshihara S., Ochiai Y., Katayama M., Ikeuchi M. Characterization of cyanobacteriochrome TePixJ from a thermophilic cyanobacterium Thermosynechococcus elongatus strain BP-1. Plant Cell Physiol. 2006, 47:1251-1261.
16. Kilian O., Steunou A.S., Fazeli F., Bailey S., Bhaya D., Grossman A.R. Responses of a thermophilic Synechococcus isolate from the microbial mat of Octopus Spring to light. Appl. Environ. Microbiol. 2007, 73:4268-4278.
17. Kim S.-W., Keasling J.D. Metabolic engineering of the nonmevalonate isopentenyl diphosphate synthesis pathway in Escherichia coli enhances lycopene production. Biotechnol. Bioeng. 2001, 72:408-415.
18. Kusakabe T., Tatsuke T., Tsuruno K., Hirokawa Y., Atsumi S., Liao J.C., Hanai T. Engineering a synthetic pathway in cyanobacteria for isopropanol production directly from carbon dioxide and light. Metab. Eng. 2013, 20:101-108.
19. Li Z., Hobson P., An W., Burch M.D., House J., Yang M. Earthy odor compounds production and loss in three cyanobacterial cultures. Water Res. 2012, 46:5165-5173.
20. Lindberg P., Park S., Melis A. Engineering a platform for photosynthetic isoprene production in cyanobacteria, using Synechocystis as the model organism. Metab. Eng. 2010, 12:70-79.
21. Liu X., Sheng J., Curtiss R. Fatty acid production in genetically modified cyanobacteria. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:6899-6904.
22. Martin V.J., Pitera D.J., Withers S.T., Newman J.D., Keasling J.D. Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. Nat. Biotechnol. 2003, 21:796-802.
23. Maruyama T., Ito M., Kiuchi F., Honda G. Molecular cloning, functional expression and characterization of d-limonene synthase from Schizonepeta tenuifolia. Biol. Pharm. Bull. 2001, 24:373-377.
24. Masukawa H., Kitashima M., Inoue K., Sakurai H., Hausinger R.P. Genetic engineering of cyanobacteria to enhance biohydrogen production from sunlight and water. Ambio 2012, 41(Suppl. 2):169-173.
25. Midorikawa T., Narikawa R., Ikeuchi M. A deletion mutation in the spacing within the psaA core promoter enhances transcription in a cyanobacterium Synechocystis sp. PCC 6803. Plant Cell Physiol. 2012, 53:164-172.
26. Miura Y., Kondo K., Saito T., Shimada H., Fraser P.D., Misawa N. Production of the carotenoids lycopene, β-carotene, and astaxanthin in the food yeast Candida utilis. Appl. Environ. Microbiol. 1998, 64:1226-1229.
27. Montero O., Sánchez-Guijo A., Lubián L.M., Martínez-Rodríguez G. Changes in membrane lipids and carotenoids during light acclimation in a marine cyanobacterium Synechococcus sp. J. Biosci. 2012, 37:635-645.
28. Nowicka B., Kruk J. Occurrence, biosynthesis and function of isoprenoid quinones. Biochim. Biophys. Acta 2010, 1797:1587-1605.
29. Peralta-Yahya P.P., Ouellet M., Chan R., Mukhopadhyay A., Keasling J.D., Lee T.S. Identification and microbial production of a terpene-based advanced biofuel. Nat. Commun. 2011, 2:483.
30. Rippka R. Isolation and purification of cyanobacteria. Methods Enzymol. 1988, 167:3-27.
31. Saenz J.P., Waterbury J.B., Eglinton T.I., Summons R.E. Hopanoids in marine cyanobacteria: probing their phylogenetic distribution and biological role. Geobiology 2012, 10:311-319.
32. Satoh S., Ikeuchi M., Mimuro M., Tanaka A. Chlorophyll b expressed in cyanobacteria functions as a light-harvesting antenna in photosystem I through flexibility of the proteins. J. Biol. Chem. 2001, 276:4293-4297.
33. Takahama K., Matsuoka M., Nagahama K., Ogawa T. Construction and analysis of a recombinant cyanobacterium expressing a chromosomally inserted gene for an ethylene-forming enzyme at the psbAI locus. J. Biosci. Bioeng. 2003, 95:302-305.
34. Takaichi S. Carotenoids in algae: distributions, biosyntheses and functions. Mar. Drugs 2011, 9:1101-1118.
35. Wang W., Liu X., Lu X. Engineering cyanobacteria to improve photosynthetic production of alka(e)nes. Biotechnol. Biofuels 2013, 6:69.
36. Watanabe S., Ohbayashi R., Shiwa Y., Noda A., Kanesaki Y., Chibazakura T., Yoshikawa H. Light-dependent and asynchronous replication of cyanobacterial multi-copy chromosomes. Mol. Microbiol. 2012, 83:856-865.
37. Wriessnegger T., Pichler H. Yeast metabolic engineering-targeting sterol metabolism and terpenoid formation. Prog. Lipid Res. 2013, 52:277-293.
38. Yin X., Proteau P.J. Characterization of native and histidine-tagged deoxyxylulose 5-phosphate reductoisomerase from the cyanobacterium Synechocystis sp. PCC6803. Biochim. Biophys. Acta 2003, 1652:75-81.
39. Yoshihara S., Katayama M., Geng X., Ikeuchi M. Cyanobacterial phytochrome-like PixJ1 holoprotein shows novel reversible photoconversion between blue- and green-absorbing forms. Plant Cell Physiol. 2004, 45:1729-1737.