메뉴 건너뛰기




Volumn 8, Issue JULY, 2014, Pages

Exercise reverses the effects of early life stress on orexin cell reactivity in male but not female rats

Author keywords

Exercise; Hypocretin; Hypothalamus; Maternal separation; Orexin; Plasticity; Sex differences; Stress

Indexed keywords

OREXIN; PROTEIN FOS; TYROSINE 3 MONOOXYGENASE;

EID: 84904597218     PISSN: 16625153     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnbeh.2014.00244     Document Type: Article
Times cited : (63)

References (54)
  • 1
    • 32444451651 scopus 로고    scopus 로고
    • Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress
    • doi: 10.1126/science.1120972
    • Berton, O., McClung, C. A., Dileone, R. J., Krishnan, V., Renthal, W., Russo, S. J., et al. (2006). Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science 311, 864-868. doi: 10.1126/science.1120972
    • (2006) Science , vol.311 , pp. 864-868
    • Berton, O.1    McClung, C.A.2    Dileone, R.J.3    Krishnan, V.4    Renthal, W.5    Russo, S.J.6
  • 2
    • 84856431680 scopus 로고    scopus 로고
    • Anxiety-and depression-like behaviors are accompanied by an increase in oxidative stress in a rat model of fetal alcohol spectrum disorders: Protective effects of voluntary physical exercise
    • doi: 10.1016/j.neuropharm.2011.10.006
    • Brocardo, P. S., Boehme, F., Patten, A., Cox, A., Gil-Mohapel, J., and Christie, B. R. (2012). Anxiety-and depression-like behaviors are accompanied by an increase in oxidative stress in a rat model of fetal alcohol spectrum disorders: Protective effects of voluntary physical exercise. Neuropharmacology 62, 1607-1618. doi: 10.1016/j.neuropharm.2011.10.006
    • (2012) Neuropharmacology , vol.62 , pp. 1607-1618
    • Brocardo, P.S.1    Boehme, F.2    Patten, A.3    Cox, A.4    Gil-Mohapel, J.5    Christie, B.R.6
  • 3
    • 34447531745 scopus 로고    scopus 로고
    • Reduced orexin levels in the cerebrospinal fluid of suicidal patients with major depressive disorder
    • doi: 10.1016/j.euroneuro.2007.01.005
    • Brundin, L., Bjorkqvist, M., Petersen, A., and Traskman-Bendz, L. (2007). Reduced orexin levels in the cerebrospinal fluid of suicidal patients with major depressive disorder. Eur. Neuropsychopharmacol. 17, 573-579. doi: 10.1016/j.euroneuro.2007.01.005
    • (2007) Eur. Neuropsychopharmacol. , vol.17 , pp. 573-579
    • Brundin, L.1    Bjorkqvist, M.2    Petersen, A.3    Traskman-Bendz, L.4
  • 4
    • 58149093295 scopus 로고    scopus 로고
    • Increased orexin levels in the cerebrospinal fluid the first year after a suicide attempt
    • doi: 10.1016/j.jad.2008.04.011
    • Brundin, L., Bjorkqvist, M., Traskman-Bendz, L., and Petersen, A. (2009). Increased orexin levels in the cerebrospinal fluid the first year after a suicide attempt. J. Affect. Disord. 113, 179-182. doi: 10.1016/j.jad.2008.04.011
    • (2009) J. Affect. Disord. , vol.113 , pp. 179-182
    • Brundin, L.1    Bjorkqvist, M.2    Traskman-Bendz, L.3    Petersen, A.4
  • 5
    • 0033968689 scopus 로고    scopus 로고
    • The effects of early rearing environment on the development of GABAA and central benzodiazepine receptor levels and novelty-induced fearfulness in the rat
    • doi: 10.1016/S0893-133X(99)00110-4
    • Caldji, C., Francis, D., Sharma, S., Plotsky, P. M., and Meaney, M. J. (2000). The effects of early rearing environment on the development of GABAA and central benzodiazepine receptor levels and novelty-induced fearfulness in the rat. Neuropsychopharmacology 22, 219-229. doi: 10.1016/S0893-133X(99)00110-4
    • (2000) Neuropsychopharmacology , vol.22 , pp. 219-229
    • Caldji, C.1    Francis, D.2    Sharma, S.3    Plotsky, P.M.4    Meaney, M.J.5
  • 6
    • 84900526349 scopus 로고    scopus 로고
    • Policy: NIH to balance sex in cell and animal studies
    • doi: 10.1038/509282a
    • Clayton, J. A., and Collins, F. S. (2014). Policy: NIH to balance sex in cell and animal studies. Nature 509, 282-283. doi: 10.1038/509282a
    • (2014) Nature , vol.509 , pp. 282-283
    • Clayton, J.A.1    Collins, F.S.2
  • 7
    • 42049086308 scopus 로고    scopus 로고
    • Elevated inflammation levels in depressed adults with a history of childhood maltreatment
    • doi: 10.1001/archpsyc.65.4.409
    • Danese, A., Moffitt, T. E., Pariante, C. M., Ambler, A., Poulton, R., and Caspi, A. (2008). Elevated inflammation levels in depressed adults with a history of childhood maltreatment. Arch. Gen. Psychiatry 65, 409-415. doi: 10.1001/archpsyc.65.4.409
    • (2008) Arch. Gen. Psychiatry , vol.65 , pp. 409-415
    • Danese, A.1    Moffitt, T.E.2    Pariante, C.M.3    Ambler, A.4    Poulton, R.5    Caspi, A.6
  • 8
    • 3242699065 scopus 로고    scopus 로고
    • Maternal separation in rats leads to anxiety-like behavior and a blunted ACTH response and altered neurotransmitter levels in response to a subsequent stressor
    • doi: 10.1023/B:MEBR.0000027412.19664.b3
    • Daniels, W. M., Pietersen, C. Y., Carstens, M. E., and Stein, D. J. (2004). Maternal separation in rats leads to anxiety-like behavior and a blunted ACTH response and altered neurotransmitter levels in response to a subsequent stressor. Metab. Brain Dis. 19, 3-14. doi: 10.1023/B:MEBR.0000027412.19664.b3
    • (2004) Metab. Brain Dis. , vol.19 , pp. 3-14
    • Daniels, W.M.1    Pietersen, C.Y.2    Carstens, M.E.3    Stein, D.J.4
  • 9
    • 0035783476 scopus 로고    scopus 로고
    • Stressor categorization: Acute physical and psychological stressors elicit distinctive recruitment patterns in the amygdala and in medullary noradrenergic cell groups
    • doi: 10.1046/j.0953-816x.2001.01733.x
    • Dayas, C. V., Buller, K. M., Crane, J. W., Xu, Y., and Day, T. A. (2001). Stressor categorization: acute physical and psychological stressors elicit distinctive recruitment patterns in the amygdala and in medullary noradrenergic cell groups. Eur. J. Neurosci. 14, 1143-1152. doi: 10.1046/j.0953-816x.2001.01733.x
    • (2001) Eur. J. Neurosci. , vol.14 , pp. 1143-1152
    • Dayas, C.V.1    Buller, K.M.2    Crane, J.W.3    Xu, Y.4    Day, T.A.5
  • 10
    • 0033046214 scopus 로고    scopus 로고
    • Neuroendocrine responses to an emotional stressor: Evidence for involvement of the medial but not the central amygdala
    • doi: 10.1046/j.1460-9568.1999.00645.x
    • Dayas, C. V., Buller, K. M., and Day, T. A. (1999). Neuroendocrine responses to an emotional stressor: evidence for involvement of the medial but not the central amygdala. Eur. J. Neurosci. 11, 2312-2322. doi: 10.1046/j.1460-9568.1999.00645.x
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 2312-2322
    • Dayas, C.V.1    Buller, K.M.2    Day, T.A.3
  • 11
    • 37349004777 scopus 로고    scopus 로고
    • Stimuli linked to ethanol availability activate hypothalamic CART and orexin neurons in a reinstatement model of relapse
    • doi: 10.1016/j.biopsych.2007.02.002
    • Dayas, C. V., Mcgranahan, T. M., Martin-Fardon, R., and Weiss, F. (2008). Stimuli linked to ethanol availability activate hypothalamic CART and orexin neurons in a reinstatement model of relapse. Biol. Psychiatry 63, 152-157. doi: 10.1016/j.biopsych.2007.02.002
    • (2008) Biol. Psychiatry , vol.63 , pp. 152-157
    • Dayas, C.V.1    McGranahan, T.M.2    Martin-Fardon, R.3    Weiss, F.4
  • 12
    • 70349472541 scopus 로고    scopus 로고
    • Reduced alcohol consumption in mice with access to a running wheel
    • doi: 10.1016/j.alcohol.2009.06.003
    • Ehringer, M. A., Hoft, N. R., and Zunhammer, M. (2009). Reduced alcohol consumption in mice with access to a running wheel. Alcohol 43, 443-452. doi: 10.1016/j.alcohol.2009.06.003
    • (2009) Alcohol , vol.43 , pp. 443-452
    • Ehringer, M.A.1    Hoft, N.R.2    Zunhammer, M.3
  • 13
    • 23844524852 scopus 로고    scopus 로고
    • Orexin expression and function: Glucocorticoid manipulation, stress, and feeding studies
    • doi: 10.1210/en.2005-0496
    • Ford, G. K., Al-Barazanji, K. A., Wilson, S., Jones, D. N., Harbuz, M. S., and Jessop, D. S. (2005). Orexin expression and function: glucocorticoid manipulation, stress, and feeding studies. Endocrinology 146, 3724-3731. doi: 10.1210/en.2005-0496
    • (2005) Endocrinology , vol.146 , pp. 3724-3731
    • Ford, G.K.1    Al-Barazanji, K.A.2    Wilson, S.3    Jones, D.N.4    Harbuz, M.S.5    Jessop, D.S.6
  • 14
    • 70350231772 scopus 로고    scopus 로고
    • Hypocretin/orexin contributes to the expression of some but not all forms of stress and arousal
    • doi: 10.1111/j.1460-9568.2009.06952.x
    • Furlong, T. M., Vianna, D. M. L., Liu, L., and Carrive, P. (2009). Hypocretin/orexin contributes to the expression of some but not all forms of stress and arousal. Eur. J. Neurosci. 30, 1603-1614. doi: 10.1111/j.1460-9568.2009.06952.x
    • (2009) Eur. J. Neurosci. , vol.30 , pp. 1603-1614
    • Furlong, T.M.1    Vianna, D.M.L.2    Liu, L.3    Carrive, P.4
  • 15
    • 0037386918 scopus 로고    scopus 로고
    • Freewheel running prevents learned helplessness/behavioral depression: Role of dorsal raphe serotonergic neurons
    • Greenwood, B. N., Foley, T. E., Day, H. E., Campisi, J., Hammack, S. H., Campeau, S., et al. (2003). Freewheel running prevents learned helplessness/behavioral depression: role of dorsal raphe serotonergic neurons. J. Neurosci. 23, 2889-2898.
    • (2003) J. Neurosci. , vol.23 , pp. 2889-2898
    • Greenwood, B.N.1    Foley, T.E.2    Day, H.E.3    Campisi, J.4    Hammack, S.H.5    Campeau, S.6
  • 16
    • 84873322861 scopus 로고    scopus 로고
    • Exercise-induced stress resistance is independent of exercise controllability and the medial prefrontal cortex
    • doi: 10.1111/ejn.12044
    • Greenwood, B. N., Spence, K. G., Crevling, D. M., Clark, P. J., Craig, W. C., and Fleshner, M. (2013). Exercise-induced stress resistance is independent of exercise controllability and the medial prefrontal cortex. Eur. J. Neurosci. 37, 469-478. doi: 10.1111/ejn.12044
    • (2013) Eur. J. Neurosci. , vol.37 , pp. 469-478
    • Greenwood, B.N.1    Spence, K.G.2    Crevling, D.M.3    Clark, P.J.4    Craig, W.C.5    Fleshner, M.6
  • 17
    • 33748806552 scopus 로고    scopus 로고
    • Arousal and reward: A dichotomy in orexin function
    • doi: 10.1016/j.tins.2006.08.002
    • Harris, G. C., and Aston-Jones, G. (2006). Arousal and reward: a dichotomy in orexin function. Trends Neurosci. 29, 571-577. doi: 10.1016/j.tins.2006.08.002
    • (2006) Trends Neurosci. , vol.29 , pp. 571-577
    • Harris, G.C.1    Aston-Jones, G.2
  • 18
    • 84867889952 scopus 로고    scopus 로고
    • Putative genes mediating the effects of orexins in the posterior paraventricular thalamus on neuroendocrine and behavioral adaptations to repeated stress
    • doi: 10.1016/j.brainresbull.2012.09.002
    • Heydendael, W., Sengupta, A., and Bhatnagar, S. (2012). Putative genes mediating the effects of orexins in the posterior paraventricular thalamus on neuroendocrine and behavioral adaptations to repeated stress. Brain Res. Bull 89, 203-210. doi: 10.1016/j.brainresbull.2012.09.002
    • (2012) Brain Res. Bull , vol.89 , pp. 203-210
    • Heydendael, W.1    Sengupta, A.2    Bhatnagar, S.3
  • 20
    • 79955988304 scopus 로고    scopus 로고
    • Orexin-1 receptor signalling within the ventral tegmental area, but not the paraventricular thalamus, is critical to regulating cue-induced reinstatement of cocaine-seeking
    • doi: 10.1017/S1461145711000423
    • James, M. H., Charnley, J. L., Levi, E. M., Jones, E., Yeoh, J. W., Smith, D. W., et al. (2011). Orexin-1 receptor signalling within the ventral tegmental area, but not the paraventricular thalamus, is critical to regulating cue-induced reinstatement of cocaine-seeking. Int. J. Neuropsychopharmacol. 14, 684-690. doi: 10.1017/S1461145711000423
    • (2011) Int. J. Neuropsychopharmacol. , vol.14 , pp. 684-690
    • James, M.H.1    Charnley, J.L.2    Levi, E.M.3    Jones, E.4    Yeoh, J.W.5    Smith, D.W.6
  • 21
    • 84874388412 scopus 로고    scopus 로고
    • What about me? The PVT: A role for the paraventricular thalamus (PVT) in drug-seeking behavior
    • doi: 10.3389/fnbeh.2013.00018
    • James, M. H., and Dayas, C. V. (2013). What about me? The PVT: a role for the paraventricular thalamus (PVT) in drug-seeking behavior. Front. Behav. Neurosci. 7:18. doi: 10.3389/fnbeh.2013.00018
    • (2013) Front. Behav. Neurosci. , vol.7 , pp. 18
    • James, M.H.1    Dayas, C.V.2
  • 22
    • 84865656920 scopus 로고    scopus 로고
    • Insights for developing pharmacological treatments for psychostimulant relapse targeting hypothalamic peptide systems
    • doi: 10.4172/2155-6105.S4-008
    • James, M. H., Yeoh, J. W., Graham, B. A., and Dayas, C. V. (2012). Insights for developing pharmacological treatments for psychostimulant relapse targeting hypothalamic peptide systems. Addict. Res. Ther. 4, 1-13. doi: 10.4172/2155-6105.S4-008
    • (2012) Addict. Res. Ther. , vol.4 , pp. 1-13
    • James, M.H.1    Yeoh, J.W.2    Graham, B.A.3    Dayas, C.V.4
  • 23
    • 84863883736 scopus 로고    scopus 로고
    • Orexin, stress, and anxiety/panic states
    • doi: 10.1016/B978-0-444-59489-1.00009-4
    • Johnson, P. L., Molosh, A., Fitz, S. D., Truitt, W. A., and Shekhar, A. (2012). Orexin, stress, and anxiety/panic states. Prog. Brain Res. 198, 133-161. doi: 10.1016/B978-0-444-59489-1.00009-4
    • (2012) Prog. Brain Res. , vol.198 , pp. 133-161
    • Johnson, P.L.1    Molosh, A.2    Fitz, S.D.3    Truitt, W.A.4    Shekhar, A.5
  • 24
    • 0024324880 scopus 로고
    • Regulation of dopamine function in the nucleus accumbens of the rat by the thalamic paraventricular nucleus and adjacent midline nuclei
    • doi: 10.1007/BF00248914
    • Jones, M. W., Kilpatrick, I. C., and Phillipson, O. T. (1989). Regulation of dopamine function in the nucleus accumbens of the rat by the thalamic paraventricular nucleus and adjacent midline nuclei. Exp. Brain Res. 76, 572-580. doi: 10.1007/BF00248914
    • (1989) Exp. Brain Res. , vol.76 , pp. 572-580
    • Jones, M.W.1    Kilpatrick, I.C.2    Phillipson, O.T.3
  • 25
    • 26844500048 scopus 로고    scopus 로고
    • Orexin (hypocretin) innervation of the paraventricular nucleus of the thalamus
    • doi: 10.1016/j.brainres.2005.08.035
    • Kirouac, G. J., Parsons, M. P., and Li, S. (2005). Orexin (hypocretin) innervation of the paraventricular nucleus of the thalamus. Brain Res. 1059, 179-188. doi: 10.1016/j.brainres.2005.08.035
    • (2005) Brain Res. , vol.1059 , pp. 179-188
    • Kirouac, G.J.1    Parsons, M.P.2    Li, S.3
  • 26
    • 0032191915 scopus 로고    scopus 로고
    • Invited review c-Fos as a transcription factor: A stressful (re)view from a functional map
    • doi: 10.1016/S0197-0186(98)00023-0
    • Kovács, K. J. (1998). Invited review c-Fos as a transcription factor: a stressful (re)view from a functional map. Neurochem. Int. 33, 287-297. doi: 10.1016/S0197-0186(98)00023-0
    • (1998) Neurochem. Int. , vol.33 , pp. 287-297
    • Kovács, K.J.1
  • 27
    • 0000905566 scopus 로고    scopus 로고
    • Centrally administered orexin/hypocretin activates HPA axis in rats
    • doi: 10.1097/00001756-200006260-00034
    • Kuru, M., Ueta, Y., Serino, R., Nakazato, M., Yamamoto, Y., Shibuya, I., et al. (2000). Centrally administered orexin/hypocretin activates HPA axis in rats. Neuroreport 11, 1977-1980. doi: 10.1097/00001756-200006260-00034
    • (2000) Neuroreport , vol.11 , pp. 1977-1980
    • Kuru, M.1    Ueta, Y.2    Serino, R.3    Nakazato, M.4    Yamamoto, Y.5    Shibuya, I.6
  • 28
    • 0034000440 scopus 로고    scopus 로고
    • Long-term behavioral and neuroendocrine adaptations to adverse early experience
    • doi: 10.1016/S0079-6123(08)62132-9
    • Ladd, C. O., Huot, R. L., Thrivikraman, K. V., Nemeroff, C. B., Meaney, M. J., and Plotsky, P. M. (2000). Long-term behavioral and neuroendocrine adaptations to adverse early experience. Prog. Brain Res. 122, 81-103. doi: 10.1016/S0079-6123(08)62132-9
    • (2000) Prog. Brain Res. , vol.122 , pp. 81-103
    • Ladd, C.O.1    Huot, R.L.2    Thrivikraman, K.V.3    Nemeroff, C.B.4    Meaney, M.J.5    Plotsky, P.M.6
  • 29
    • 84860711189 scopus 로고    scopus 로고
    • Hypothalamic orexin-A neurons are involved in the response of the brain stress system to morphine withdrawal
    • doi: 10.1371/journal.pone.0036871
    • Laorden, M. L., Ferenczi, S., Pinter-Kubler, B., Gonzalez-Martin, L. L., Lasheras, M. C., Kovacs, K. J., et al. (2012). Hypothalamic orexin-A neurons are involved in the response of the brain stress system to morphine withdrawal. PLoS ONE 7:e36871. doi: 10.1371/journal.pone.0036871
    • (2012) PLoS ONE , vol.7
    • Laorden, M.L.1    Ferenczi, S.2    Pinter-Kubler, B.3    Gonzalez-Martin, L.L.4    Lasheras, M.C.5    Kovacs, K.J.6
  • 30
    • 84879189910 scopus 로고    scopus 로고
    • Beneficial effects of fluoxetine, reboxetine, venlafaxine, and voluntary running exercise in stressed male rats with anxiety-and depression-like behaviors
    • doi: 10.1016/j.bbr.2013.05.018
    • Lapmanee, S., Charoenphandhu, J., and Charoenphandhu, N. (2013). Beneficial effects of fluoxetine, reboxetine, venlafaxine, and voluntary running exercise in stressed male rats with anxiety-and depression-like behaviors. Behav. Brain Res. 250, 316-325. doi: 10.1016/j.bbr.2013.05.018
    • (2013) Behav. Brain Res. , vol.250 , pp. 316-325
    • Lapmanee, S.1    Charoenphandhu, J.2    Charoenphandhu, N.3
  • 31
    • 77249169672 scopus 로고    scopus 로고
    • Changes in emotional behavior produced by orexin microinjections in the paraventricular nucleus of the thalamus
    • doi: 10.1016/j.pbb.2009.12.016
    • Li, Y., Li, S., Wei, C., Wang, H., Sui, N., and Kirouac, G. J. (2010a). Changes in emotional behavior produced by orexin microinjections in the paraventricular nucleus of the thalamus. Pharmacol. Biochem. Behav. 95, 121-128. doi: 10.1016/j.pbb.2009.12.016
    • (2010) Pharmacol. Biochem. Behav. , vol.95 , pp. 121-128
    • Li, Y.1    Li, S.2    Wei, C.3    Wang, H.4    Sui, N.5    Kirouac, G.J.6
  • 32
    • 77957359098 scopus 로고    scopus 로고
    • Orexins in the paraventricular nucleus of the thalamus mediate anxiety-like responses in rats
    • doi: 10.1007/s00213-010-1948-y
    • Li, Y., Li, S., Wei, C., Wang, H., Sui, N., and Kirouac, G. J. (2010b). Orexins in the paraventricular nucleus of the thalamus mediate anxiety-like responses in rats. Psychopharmacology (Berl). 212, 251-265. doi: 10.1007/s00213-010-1948-y
    • (2010) Psychopharmacology (Berl). , vol.212 , pp. 251-265
    • Li, Y.1    Li, S.2    Wei, C.3    Wang, H.4    Sui, N.5    Kirouac, G.J.6
  • 33
    • 41149167542 scopus 로고    scopus 로고
    • Orexin signaling mediates the antidepressant-like effect of calorie restriction
    • doi: 10.1523/JNEUROSCI.5584-07.2008
    • Lutter, M., Krishnan, V., Russo, S. J., Jung, S., Mcclung, C. A., and Nestler, E. J. (2008). Orexin signaling mediates the antidepressant-like effect of calorie restriction. J. Neurosci. 28, 3071-3075. doi: 10.1523/JNEUROSCI.5584-07.2008
    • (2008) J. Neurosci. , vol.28 , pp. 3071-3075
    • Lutter, M.1    Krishnan, V.2    Russo, S.J.3    Jung, S.4    McClung, C.A.5    Nestler, E.J.6
  • 34
    • 78650179908 scopus 로고    scopus 로고
    • Voluntary exercise and palatable high-fat diet both improve behavioural profile and stress responses in male rats exposed to early life stress: Role of hippocampus
    • doi: 10.1016/j.psyneuen.2010.05.012
    • Maniam, J., and Morris, M. J. (2010). Voluntary exercise and palatable high-fat diet both improve behavioural profile and stress responses in male rats exposed to early life stress: role of hippocampus. Psychoneuroendocrinology 35, 1553-1564. doi: 10.1016/j.psyneuen.2010.05.012
    • (2010) Psychoneuroendocrinology , vol.35 , pp. 1553-1564
    • Maniam, J.1    Morris, M.J.2
  • 36
    • 0030038741 scopus 로고    scopus 로고
    • Early environmental regulation of forebrain glucocorticoid receptor gene expression: Implications for adrenocortical responses to stress
    • doi: 10.1159/000111395
    • Meaney, M. J., Diorio, J., Francis, D., Widdowson, J., Laplante, P., Caldji, C., et al. (1996). Early environmental regulation of forebrain glucocorticoid receptor gene expression: implications for adrenocortical responses to stress. Dev. Neurosci. 18, 49-72. doi: 10.1159/000111395
    • (1996) Dev. Neurosci. , vol.18 , pp. 49-72
    • Meaney, M.J.1    Diorio, J.2    Francis, D.3    Widdowson, J.4    Laplante, P.5    Caldji, C.6
  • 37
    • 34347346105 scopus 로고    scopus 로고
    • Epigenetic mechanisms of perinatal programming of hypothalamic-pituitary-adrenal function and health
    • doi: 10.1016/j.molmed.2007.05.003
    • Meaney, M. J., Szyf, M., and Seckl, J. R. (2007). Epigenetic mechanisms of perinatal programming of hypothalamic-pituitary-adrenal function and health. Trends Mol. Med. 13, 269-277. doi: 10.1016/j.molmed.2007.05.003
    • (2007) Trends Mol. Med. , vol.13 , pp. 269-277
    • Meaney, M.J.1    Szyf, M.2    Seckl, J.R.3
  • 38
    • 79953885576 scopus 로고    scopus 로고
    • Maternal separation in early life impairs tumor immunity in adulthood in the F344 rat
    • doi: 10.3109/10253890.2010.548014
    • Nakamura, T., Walker, A. K., Sominsky, L., Allen, T., Rosengren, S., and Hodgson, D. M. (2011). Maternal separation in early life impairs tumor immunity in adulthood in the F344 rat. Stress 14, 335-343. doi: 10.3109/10253890.2010.548014
    • (2011) Stress , vol.14 , pp. 335-343
    • Nakamura, T.1    Walker, A.K.2    Sominsky, L.3    Allen, T.4    Rosengren, S.5    Hodgson, D.M.6
  • 39
    • 84863778971 scopus 로고    scopus 로고
    • The social defeat animal model of depression shows diminished levels of orexin in mesocortical regions of the dopamine system, and of dynorphin and orexin in the hypothalamus
    • doi: 10.1016/j.neuroscience.2012.05.033
    • Nocjar, C., Zhang, J., Feng, P., and Panksepp, J. (2012). The social defeat animal model of depression shows diminished levels of orexin in mesocortical regions of the dopamine system, and of dynorphin and orexin in the hypothalamus. Neuroscience 218, 138-153. doi: 10.1016/j.neuroscience.2012.05.033
    • (2012) Neuroscience , vol.218 , pp. 138-153
    • Nocjar, C.1    Zhang, J.2    Feng, P.3    Panksepp, J.4
  • 40
    • 33846186310 scopus 로고    scopus 로고
    • Functional and anatomical connection between the paraventricular nucleus of the thalamus and dopamine fibers of the nucleus accumbens
    • doi: 10.1002/cne.21224
    • Parsons, M. P., Li, S., and Kirouac, G. J. (2007). Functional and anatomical connection between the paraventricular nucleus of the thalamus and dopamine fibers of the nucleus accumbens. J. Comp. Neurol. 500, 1050-1063. doi: 10.1002/cne.21224
    • (2007) J. Comp. Neurol. , vol.500 , pp. 1050-1063
    • Parsons, M.P.1    Li, S.2    Kirouac, G.J.3
  • 43
    • 0027195888 scopus 로고
    • Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats
    • doi: 10.1016/0169-328X(93)90189-V
    • Plotsky, P. M., and Meaney, M. J. (1993). Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats. Brain Res. Mol. Brain Res. 18, 195-200. doi: 10.1016/0169-328X(93)90189-V
    • (1993) Brain Res. Mol. Brain Res. , vol.18 , pp. 195-200
    • Plotsky, P.M.1    Meaney, M.J.2
  • 44
    • 33645854064 scopus 로고    scopus 로고
    • Exposure to repetitive versus varied stress during prenatal development generates two distinct anxiogenic and neuroendocrine profiles in adulthood
    • doi: 10.1210/en.2005-1054
    • Richardson, H. N., Zorrilla, E. P., Mandyam, C. D., and Rivier, C. L. (2006). Exposure to repetitive versus varied stress during prenatal development generates two distinct anxiogenic and neuroendocrine profiles in adulthood. Endocrinology 147, 2506-2517. doi: 10.1210/en.2005-1054
    • (2006) Endocrinology , vol.147 , pp. 2506-2517
    • Richardson, H.N.1    Zorrilla, E.P.2    Mandyam, C.D.3    Rivier, C.L.4
  • 45
    • 1542270814 scopus 로고    scopus 로고
    • Centrally administered orexin-A activates corticotropin-releasing factor-containing neurons in the hypothalamic paraventricular nucleus and central amygdaloid nucleus of rats: Possible involvement of central orexins on stress-activated central CRF neurons
    • doi: 10.1016/j.regpep.2003.12.014
    • Sakamoto, F., Yamada, S., and Ueta, Y. (2004). Centrally administered orexin-A activates corticotropin-releasing factor-containing neurons in the hypothalamic paraventricular nucleus and central amygdaloid nucleus of rats: possible involvement of central orexins on stress-activated central CRF neurons. Regul. Pept. 118, 183-191. doi: 10.1016/j.regpep.2003.12.014
    • (2004) Regul. Pept. , vol.118 , pp. 183-191
    • Sakamoto, F.1    Yamada, S.2    Ueta, Y.3
  • 46
    • 0027300543 scopus 로고
    • Neurochemical identification of fos-positive neurons using two-colour immunoperoxidase staining
    • doi: 10.1016/0165-0270(93)90023-K
    • Smith, D. W., and Day, T. A. (1993). Neurochemical identification of fos-positive neurons using two-colour immunoperoxidase staining. J. Neurosci. Methods 47, 73-83. doi: 10.1016/0165-0270(93)90023-K
    • (1993) J. Neurosci. Methods , vol.47 , pp. 73-83
    • Smith, D.W.1    Day, T.A.2
  • 47
    • 58749084148 scopus 로고    scopus 로고
    • Aerobic exercise decreases the positive-reinforcing effects of cocaine
    • doi: 10.1016/j.drugalcdep.2008.05.006
    • Smith, M. A., Schmidt, K. T., Iordanou, J. C., and Mustroph, M. L. (2008). Aerobic exercise decreases the positive-reinforcing effects of cocaine. Drug Alcohol Depend. 98, 129-135. doi: 10.1016/j.drugalcdep.2008.05.006
    • (2008) Drug Alcohol Depend. , vol.98 , pp. 129-135
    • Smith, M.A.1    Schmidt, K.T.2    Iordanou, J.C.3    Mustroph, M.L.4
  • 48
    • 77955847332 scopus 로고    scopus 로고
    • Chronic forced exercise during adolescence decreases cocaine conditioned place preference in Lewis rats
    • doi: 10.1016/j.bbr.2010.06.033
    • Thanos, P. K., Tucci, A., Stamos, J., Robison, L., Wang, G. J., Anderson, B. J., et al. (2010). Chronic forced exercise during adolescence decreases cocaine conditioned place preference in Lewis rats. Behav. Brain Res. 215, 77-82. doi: 10.1016/j.bbr.2010.06.033
    • (2010) Behav. Brain Res. , vol.215 , pp. 77-82
    • Thanos, P.K.1    Tucci, A.2    Stamos, J.3    Robison, L.4    Wang, G.J.5    Anderson, B.J.6
  • 49
    • 0032582716 scopus 로고    scopus 로고
    • Distribution of orexin receptor mRNA in the rat brain
    • doi: 10.1016/S0014-5793(98)01266-6
    • Trivedi, P., Yu, H., Macneil, D. J., Van Der Ploeg, L. H., and Guan, X. M. (1998). Distribution of orexin receptor mRNA in the rat brain. FEBS Lett. 438, 71-75. doi: 10.1016/S0014-5793(98)01266-6
    • (1998) FEBS Lett. , vol.438 , pp. 71-75
    • Trivedi, P.1    Yu, H.2    McNeil, D.J.3    Van Der Ploeg, L.H.4    Guan, X.M.5
  • 50
    • 77958032345 scopus 로고    scopus 로고
    • Neonatal lipopolysaccharide exposure alters central cytokine responses to stress in adulthood in Wistar rats
    • doi: 10.3109/10253890.2010.489977
    • Walker, A. K., Nakamura, T., and Hodgson, D. M. (2010). Neonatal lipopolysaccharide exposure alters central cytokine responses to stress in adulthood in Wistar rats. Stress 13, 506-515. doi: 10.3109/10253890.2010.489977
    • (2010) Stress , vol.13 , pp. 506-515
    • Walker, A.K.1    Nakamura, T.2    Hodgson, D.M.3
  • 51
    • 36348975007 scopus 로고    scopus 로고
    • Maternal separation leads to persistent reductions in pain sensitivity in female rats
    • doi: 10.1016/j.jpain.2007.07.001
    • Weaver, S. A., Diorio, J., and Meaney, M. J. (2007). Maternal separation leads to persistent reductions in pain sensitivity in female rats. J. Pain 8, 962-969. doi: 10.1016/j.jpain.2007.07.001
    • (2007) J. Pain , vol.8 , pp. 962-969
    • Weaver, S.A.1    Diorio, J.2    Meaney, M.J.3
  • 52
    • 0026070408 scopus 로고
    • The infant rat separation paradigm: A novel test for novel anxiolytics
    • doi: 10.1016/0165-6147(91)90616-Z
    • Winslow, J. T., and Insel, T. R. (1991). The infant rat separation paradigm: a novel test for novel anxiolytics. Trends Pharmacol. Sci. 12, 402-404. doi: 10.1016/0165-6147(91)90616-Z
    • (1991) Trends Pharmacol. Sci. , vol.12 , pp. 402-404
    • Winslow, J.T.1    Insel, T.R.2
  • 53
    • 84898046033 scopus 로고    scopus 로고
    • Orexin antagonists for neuropsychiatric disease: Progress and potential pitfalls
    • doi: 10.3389/fnins.2014.00036
    • Yeoh, J. W., Campbell, E. J., James, M. H., Graham, B. A., and Dayas, C. V. (2014). Orexin antagonists for neuropsychiatric disease: progress and potential pitfalls. Front. Neurosci. 8:36. doi: 10.3389/fnins.2014.00036
    • (2014) Front. Neurosci. , vol.8 , pp. 36
    • Yeoh, J.W.1    Campbell, E.J.2    James, M.H.3    Graham, B.A.4    Dayas, C.V.5
  • 54
    • 84865644243 scopus 로고    scopus 로고
    • Cocaine potentiates excitatory drive in the perifornical/lateral hypothalamus
    • doi: 10.1113/jphysiol.2012.230268
    • Yeoh, J. W., James, M. H., Jobling, P., Bains, J. S., Graham, B. A., and Dayas, C. V. (2012). Cocaine potentiates excitatory drive in the perifornical/lateral hypothalamus. J. Physiol. 590, 3677-3689. doi: 10.1113/jphysiol.2012.230268
    • (2012) J. Physiol. , vol.590 , pp. 3677-3689
    • Yeoh, J.W.1    James, M.H.2    Jobling, P.3    Bains, J.S.4    Graham, B.A.5    Dayas, C.V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.