메뉴 건너뛰기




Volumn 7, Issue 5, 2012, Pages

Hypothalamic orexin-A neurons are involved in the response of the brain stress system to morphine withdrawal

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 METHYL 6 BENZOXAZOLYL) 3 (1,5 NAPHTHYRIDIN 4 YL)UREA; CORTICOSTERONE; MESSENGER RNA; MORPHINE; NALOXONE; OPIATE; OREXIN A; PLACEBO; PROTEIN C FOS; G PROTEIN COUPLED RECEPTOR; NARCOTIC AGENT; NEUROPEPTIDE; NEUROPEPTIDE RECEPTOR; OREXIN RECEPTORS; OREXINS; SIGNAL PEPTIDE;

EID: 84860711189     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036871     Document Type: Article
Times cited : (48)

References (42)
  • 1
    • 20244380014 scopus 로고    scopus 로고
    • Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
    • Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, et al. (1998) Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 92: 573-585.
    • (1998) Cell , vol.92 , pp. 573-585
    • Sakurai, T.1    Amemiya, A.2    Ishii, M.3    Matsuzaki, I.4    Chemelli, R.M.5
  • 2
    • 0008390266 scopus 로고    scopus 로고
    • The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity
    • de Lecea L, Kilduff TS, Peyron C, Gao XB, Foye PE, et al. (1998) The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity. PNAS 95: 322-327.
    • (1998) PNAS , vol.95 , pp. 322-327
    • de Lecea, L.1    Kilduff, T.S.2    Peyron, C.3    Gao, X.B.4    Foye, P.E.5
  • 3
    • 0033588184 scopus 로고    scopus 로고
    • Narcolepsy in orexin Knockout Mice: Molecular Genetics of Sleep Regulation
    • Chemelli RM, Willie JT, Sinton CM, Elmquist JK, Scammell T, et al. (1999) Narcolepsy in orexin Knockout Mice: Molecular Genetics of Sleep Regulation. Cell 98: 437-451.
    • (1999) Cell , vol.98 , pp. 437-451
    • Chemelli, R.M.1    Willie, J.T.2    Sinton, C.M.3    Elmquist, J.K.4    Scammell, T.5
  • 5
    • 0042123759 scopus 로고    scopus 로고
    • Overlapping distributions of orexin/hypocretin- and dopamine-β-hydroxylase immunoreactive fibers in rat brain regions mediating arousal, motivation, and stress
    • Baldo BA, Daniel RA, Berridge CW, Kelley AE, (2003) Overlapping distributions of orexin/hypocretin- and dopamine-β-hydroxylase immunoreactive fibers in rat brain regions mediating arousal, motivation, and stress. J Comp Neurol 464: 220-237.
    • (2003) J Comp Neurol , vol.464 , pp. 220-237
    • Baldo, B.A.1    Daniel, R.A.2    Berridge, C.W.3    Kelley, A.E.4
  • 6
    • 59349089712 scopus 로고    scopus 로고
    • The brain hypocretins and their receptors: mediators of allostatic arousal
    • Carter ME, Borg JS, de Lecea L, (2009) The brain hypocretins and their receptors: mediators of allostatic arousal. Current Opinion in Pharmacology 9: 39-45.
    • (2009) Current Opinion in Pharmacology , vol.9 , pp. 39-45
    • Carter, M.E.1    Borg, J.S.2    de Lecea, L.3
  • 7
    • 0026332080 scopus 로고
    • Physiology and Pharmacology of corticotropin releasing factor
    • Owens MJ, Nemeroff CB, (1991) Physiology and Pharmacology of corticotropin releasing factor. Pharmacol Rev 43: 425-473.
    • (1991) Pharmacol Rev , vol.43 , pp. 425-473
    • Owens, M.J.1    Nemeroff, C.B.2
  • 8
    • 0034719355 scopus 로고    scopus 로고
    • Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion
    • Delfs JM, Zhu Y, Druhan JP, Aston-Jones G, (2000) Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion. Nature 403: 430-434.
    • (2000) Nature , vol.403 , pp. 430-434
    • Delfs, J.M.1    Zhu, Y.2    Druhan, J.P.3    Aston-Jones, G.4
  • 9
    • 79251484353 scopus 로고    scopus 로고
    • CRF(2) mediates the increased noradrenergic activity in the hypothalamic paraventricular nucleus and the negative state of morphine withdrawal in rats
    • Navarro-Zaragoza J, Núñez C, Ruiz-Medina J, Laorden ML, Valverde O, et al. (2011) CRF(2) mediates the increased noradrenergic activity in the hypothalamic paraventricular nucleus and the negative state of morphine withdrawal in rats. Br J Pharmacol 162: 851-862.
    • (2011) Br J Pharmacol , vol.162 , pp. 851-862
    • Navarro-Zaragoza, J.1    Núñez, C.2    Ruiz-Medina, J.3    Laorden, M.L.4    Valverde, O.5
  • 10
    • 41549113416 scopus 로고    scopus 로고
    • Addiction and the brain antireward system
    • Koob GF, Le Moal M, (2008) Addiction and the brain antireward system. Ann Rev Physiol 59: 29-53.
    • (2008) Ann Rev Physiol , vol.59 , pp. 29-53
    • Koob, G.F.1    Le Moal, M.2
  • 11
    • 75149141234 scopus 로고    scopus 로고
    • Drug-induced and genetic alterations in stress-responsive systems: Implications for specific addictive diseases
    • Zhou Y, Proudnikov D, Yuferov V, Kreek MJ, (2010) Drug-induced and genetic alterations in stress-responsive systems: Implications for specific addictive diseases. Brain Res 1314: 235-252.
    • (2010) Brain Res , vol.1314 , pp. 235-252
    • Zhou, Y.1    Proudnikov, D.2    Yuferov, V.3    Kreek, M.J.4
  • 12
    • 0037086828 scopus 로고    scopus 로고
    • Orexin actions in hypothalamic paraventricular nucleus: physiological consequences and cellular correlates
    • Samson WK, Taylor MM, Follwell M, Ferguson AV, (2002) Orexin actions in hypothalamic paraventricular nucleus: physiological consequences and cellular correlates. Regulatory Peptides 104: 97-103.
    • (2002) Regulatory Peptides , vol.104 , pp. 97-103
    • Samson, W.K.1    Taylor, M.M.2    Follwell, M.3    Ferguson, A.V.4
  • 13
    • 0000905566 scopus 로고    scopus 로고
    • Centrally administered orexin/hypocretin activates HPA axis in rats
    • Kuru M, Ueta Y, Serino R, Nakazato M, Yamamoto Y, et al. (2000) Centrally administered orexin/hypocretin activates HPA axis in rats. NeuroReport 11.
    • (2000) NeuroReport , vol.11
    • Kuru, M.1    Ueta, Y.2    Serino, R.3    Nakazato, M.4    Yamamoto, Y.5
  • 14
    • 0037659189 scopus 로고    scopus 로고
    • Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal
    • Georgescu D, Zachariou V, Barrot M, Mieda M, Willie JT, et al. (2003) Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal. J Neurosci 23: 3106-3111.
    • (2003) J Neurosci , vol.23 , pp. 3106-3111
    • Georgescu, D.1    Zachariou, V.2    Barrot, M.3    Mieda, M.4    Willie, J.T.5
  • 15
    • 46249085450 scopus 로고    scopus 로고
    • Orexin mediates the expression of precipitated morphine withdrawal and concurrent activation of the nucleus accumbens shell
    • Sharf R, Sarhan M, DiLeone RJ, (2008) Orexin mediates the expression of precipitated morphine withdrawal and concurrent activation of the nucleus accumbens shell. Biol Psychiatry 64: 175-183.
    • (2008) Biol Psychiatry , vol.64 , pp. 175-183
    • Sharf, R.1    Sarhan, M.2    DiLeone, R.J.3
  • 16
    • 77955920536 scopus 로고    scopus 로고
    • Antagonism of orexin type 1 receptors in the locus coeruleus attenuates signs of naloxone-precipitated morphine withdrawal in rats
    • Azizi H, Mirnajafi-Zadeh J, Rohampour K, Semnanian S, (2010) Antagonism of orexin type 1 receptors in the locus coeruleus attenuates signs of naloxone-precipitated morphine withdrawal in rats. Neurosci Lett 482: 255-259.
    • (2010) Neurosci Lett , vol.482 , pp. 255-259
    • Azizi, H.1    Mirnajafi-Zadeh, J.2    Rohampour, K.3    Semnanian, S.4
  • 17
    • 33748806552 scopus 로고    scopus 로고
    • Arousal and reward: a dichotomy in orexin function
    • Harris GC, Aston-Jones G, (2006) Arousal and reward: a dichotomy in orexin function. Trends in Neurosciences 29: 571-577.
    • (2006) Trends in Neurosciences , vol.29 , pp. 571-577
    • Harris, G.C.1    Aston-Jones, G.2
  • 18
    • 33847125744 scopus 로고    scopus 로고
    • Inhibitory effects of an orexin-2 receptor antagonist on orexin A- and stress-induced ACTH responses in conscious rats
    • Chang H, Saito T, Ohiwa N, Tateoka M, Deocaris CC, et al. (2007) Inhibitory effects of an orexin-2 receptor antagonist on orexin A- and stress-induced ACTH responses in conscious rats. Neuroscience Research 57: 462-466.
    • (2007) Neuroscience Research , vol.57 , pp. 462-466
    • Chang, H.1    Saito, T.2    Ohiwa, N.3    Tateoka, M.4    Deocaris, C.C.5
  • 19
    • 34247567169 scopus 로고    scopus 로고
    • Activation of stress-related hypothalamic neuropeptide gene expression during morphine withdrawal
    • Núñez C, Foldes A, Laorden ML, Milanes MV, Kovács KJ, (2007) Activation of stress-related hypothalamic neuropeptide gene expression during morphine withdrawal. J Neurochem 101: 1060-1071.
    • (2007) J Neurochem , vol.101 , pp. 1060-1071
    • Núñez, C.1    Foldes, A.2    Laorden, M.L.3    Milanes, M.V.4    Kovács, K.J.5
  • 20
    • 67649665609 scopus 로고    scopus 로고
    • Elevated glucocorticoid levels are responsible for induction of tyrosine hydroxylase (TH) mRNA expression, phosphorylation and enzyme activity in the nucleus of the solitary tract (NTS-A2) during morphine withdrawal
    • Núñez C, Földes A, Pérez-Flores D, García-Borrón JC, Laorden ML, et al. (2009) Elevated glucocorticoid levels are responsible for induction of tyrosine hydroxylase (TH) mRNA expression, phosphorylation and enzyme activity in the nucleus of the solitary tract (NTS-A2) during morphine withdrawal. Endocrinology 150: 3118-3127.
    • (2009) Endocrinology , vol.150 , pp. 3118-3127
    • Núñez, C.1    Földes, A.2    Pérez-Flores, D.3    García-Borrón, J.C.4    Laorden, M.L.5
  • 21
    • 0036204717 scopus 로고    scopus 로고
    • Elevated extracellular CRF levels in the bed nucleus of the stria terminalis during ethanol withdrawal and reduction by subsequent ethanol intake
    • Olive MF, Koenig HN, Nannini MA, Hodge CW, (2002) Elevated extracellular CRF levels in the bed nucleus of the stria terminalis during ethanol withdrawal and reduction by subsequent ethanol intake. Pharmacology Biochemistry and Behavior 72: 213-220.
    • (2002) Pharmacology Biochemistry and Behavior , vol.72 , pp. 213-220
    • Olive, M.F.1    Koenig, H.N.2    Nannini, M.A.3    Hodge, C.W.4
  • 22
    • 0034016153 scopus 로고    scopus 로고
    • Changes in catecholaminergic pathways innervating paraventricular nucleus and pituitary-adrenal axis response during morphine dependence: implication of α1- and α2-adrenoceptors
    • Laorden ML, Fuertes G, González-Cuello A, Milanés MV, (2000) Changes in catecholaminergic pathways innervating paraventricular nucleus and pituitary-adrenal axis response during morphine dependence: implication of α1- and α2-adrenoceptors. J Pharmacol Exp Ther 293: 578-584.
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 578-584
    • Laorden, M.L.1    Fuertes, G.2    González-Cuello, A.3    Milanés, M.V.4
  • 24
    • 0025063449 scopus 로고
    • Nucleus accumbens and amygdala are possible substrates for the aversive stimulus effects of opiate withdrawal
    • Stinus L, Le Moal M, Koob GF, (1990) Nucleus accumbens and amygdala are possible substrates for the aversive stimulus effects of opiate withdrawal. Neuroscience 37: 767-773.
    • (1990) Neuroscience , vol.37 , pp. 767-773
    • Stinus, L.1    Le Moal, M.2    Koob, G.F.3
  • 25
    • 0032779967 scopus 로고    scopus 로고
    • The bed nucleus of the stria terminalis. A target site for noradrenergic actions in opiate withdrawal
    • Aston-Jones G, Delfs JM, Druhan J, Zhu Y, (1999) The bed nucleus of the stria terminalis. A target site for noradrenergic actions in opiate withdrawal. Ann N Y Acad Sci 877: 486-498.
    • (1999) Ann N Y Acad Sci , vol.877 , pp. 486-498
    • Aston-Jones, G.1    Delfs, J.M.2    Druhan, J.3    Zhu, Y.4
  • 26
    • 77956874814 scopus 로고    scopus 로고
    • Intracerebroventricular injection of orexin-A stimulates monoamine metabolism but not HPA axis in neonatal chicks
    • Katayama S, Shigemi K, Cline MA, Furuse M, (2010) Intracerebroventricular injection of orexin-A stimulates monoamine metabolism but not HPA axis in neonatal chicks. Neurosci Lett 484: 157-161.
    • (2010) Neurosci Lett , vol.484 , pp. 157-161
    • Katayama, S.1    Shigemi, K.2    Cline, M.A.3    Furuse, M.4
  • 27
    • 75749083285 scopus 로고    scopus 로고
    • Interactions of orexins/hypocretins with adrenocortical functions
    • Kagerer SM, Jöhren O, (2010) Interactions of orexins/hypocretins with adrenocortical functions. Acta Physiologica 198: 361-371.
    • (2010) Acta Physiologica , vol.198 , pp. 361-371
    • Kagerer, S.M.1    Jöhren, O.2
  • 28
    • 0020468095 scopus 로고
    • The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat
    • Sawchenko PE, Swanson LW, (1982) The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat. Brain Res Rev 4: 275-325.
    • (1982) Brain Res Rev , vol.4 , pp. 275-325
    • Sawchenko, P.E.1    Swanson, L.W.2
  • 29
    • 33750340328 scopus 로고    scopus 로고
    • Excitatory action of hypocretin/orexin on neurons of the central medial amygdala
    • Bisetti A, Cvetkovic V, Serafin M, Bayer L, Machard D, et al. (2006) Excitatory action of hypocretin/orexin on neurons of the central medial amygdala. Neuroscience 142: 999-1004.
    • (2006) Neuroscience , vol.142 , pp. 999-1004
    • Bisetti, A.1    Cvetkovic, V.2    Serafin, M.3    Bayer, L.4    Machard, D.5
  • 30
    • 1542270814 scopus 로고    scopus 로고
    • Centrally administered orexin-A activates corticotropin-releasing factor-containing neurons in the hypothalamic paraventricular nucleus and central amygdaloid nucleus of rats: possible involvement of central orexins on stress-activated central CRF neurons
    • Sakamoto F, Yamada S, Ueta Y, (2004) Centrally administered orexin-A activates corticotropin-releasing factor-containing neurons in the hypothalamic paraventricular nucleus and central amygdaloid nucleus of rats: possible involvement of central orexins on stress-activated central CRF neurons. Regulatory Peptides 118: 183-191.
    • (2004) Regulatory Peptides , vol.118 , pp. 183-191
    • Sakamoto, F.1    Yamada, S.2    Ueta, Y.3
  • 31
    • 33845310372 scopus 로고    scopus 로고
    • Activation in extended amygdala corresponds to altered hedonic processing during protracted morphine withdrawal
    • Harris GC, Aston-Jones G, (2007) Activation in extended amygdala corresponds to altered hedonic processing during protracted morphine withdrawal. Behav Brain Res 176: 251-258.
    • (2007) Behav Brain Res , vol.176 , pp. 251-258
    • Harris, G.C.1    Aston-Jones, G.2
  • 32
    • 9644262761 scopus 로고    scopus 로고
    • Role of noradrenergic projections to the bed nucleus of the stria terminalis in the regulation of the hypothalamic-pituitary-adrenal axis
    • Forray MI, Gysling K, (2004) Role of noradrenergic projections to the bed nucleus of the stria terminalis in the regulation of the hypothalamic-pituitary-adrenal axis. Brain Research Reviews 47: 145-160.
    • (2004) Brain Research Reviews , vol.47 , pp. 145-160
    • Forray, M.I.1    Gysling, K.2
  • 33
    • 78149241646 scopus 로고    scopus 로고
    • Orexins in the midline thalamus are involved in the expression of conditioned place aversion to morphine withdrawal
    • Li Y, Wang H, Qi K, Chen X, Li S, et al. (2011) Orexins in the midline thalamus are involved in the expression of conditioned place aversion to morphine withdrawal. Physiology & Behavior 102: 42-50.
    • (2011) Physiology & Behavior , vol.102 , pp. 42-50
    • Li, Y.1    Wang, H.2    Qi, K.3    Chen, X.4    Li, S.5
  • 34
    • 0036429992 scopus 로고    scopus 로고
    • Neural correlates of the motivational and somatic components of naloxone-precipitated morphine withdrawal
    • Frenois F, Cador M, Caille S, Stinus L, Le Moine C, (2002) Neural correlates of the motivational and somatic components of naloxone-precipitated morphine withdrawal. Eur J Neurosci 16: 1377-1389.
    • (2002) Eur J Neurosci , vol.16 , pp. 1377-1389
    • Frenois, F.1    Cador, M.2    Caille, S.3    Stinus, L.4    Le Moine, C.5
  • 35
    • 0028123538 scopus 로고
    • Prolonged tolerance, dependence and abstinence following subcutaneous morphine pellets implantation in the rat
    • Gold LH, Stinus L, Inturrisi CE, Koob GF, (1994) Prolonged tolerance, dependence and abstinence following subcutaneous morphine pellets implantation in the rat. Eur J Pharmacol 253: 45-51.
    • (1994) Eur J Pharmacol , vol.253 , pp. 45-51
    • Gold, L.H.1    Stinus, L.2    Inturrisi, C.E.3    Koob, G.F.4
  • 36
    • 0024849486 scopus 로고
    • Identification of morphine- and cyclic AMP-regulated phosphoprotein (MARPPs) in the locus coeruleus and other regions of rat brain: regulation by acute and chronic morphine
    • Guitart X, Nestler EJ, (1989) Identification of morphine- and cyclic AMP-regulated phosphoprotein (MARPPs) in the locus coeruleus and other regions of rat brain: regulation by acute and chronic morphine. J Neurosci 9: 4371-4387.
    • (1989) J Neurosci , vol.9 , pp. 4371-4387
    • Guitart, X.1    Nestler, E.J.2
  • 37
    • 0034509832 scopus 로고    scopus 로고
    • Differential role of corticotropin-releasing factor receptor subtypes 1 and 2 in opiate withdrawal and in relapse to opiate dependence
    • Lu L, Liu D, Ceng X, Ma L, (2000) Differential role of corticotropin-releasing factor receptor subtypes 1 and 2 in opiate withdrawal and in relapse to opiate dependence. Eur J Neurosci 12: 4398-4404.
    • (2000) Eur J Neurosci , vol.12 , pp. 4398-4404
    • Lu, L.1    Liu, D.2    Ceng, X.3    Ma, L.4
  • 38
    • 0029764770 scopus 로고    scopus 로고
    • Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB
    • Maldonado R, Blendy JA, Tzavara E, Gass P, Roques BP, et al. (1996) Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB. Science 273: 657-659.
    • (1996) Science , vol.273 , pp. 657-659
    • Maldonado, R.1    Blendy, J.A.2    Tzavara, E.3    Gass, P.4    Roques, B.P.5
  • 39
    • 7044222717 scopus 로고    scopus 로고
    • Time-Dependent Alterations in mRNA Expression of Brain Neuropeptides Regulating Energy Balance and Hypothalamo-Pituitary-Adrenal Activity after Withdrawal from Intermittent Morphine Treatment
    • Houshyar H, Manalo S, Dallman MF, (2004) Time-Dependent Alterations in mRNA Expression of Brain Neuropeptides Regulating Energy Balance and Hypothalamo-Pituitary-Adrenal Activity after Withdrawal from Intermittent Morphine Treatment. J Neurosci 24: 9414-9424.
    • (2004) J Neurosci , vol.24 , pp. 9414-9424
    • Houshyar, H.1    Manalo, S.2    Dallman, M.F.3
  • 40
    • 0034704445 scopus 로고    scopus 로고
    • A selective orexin-1 receptor antagonist reduces food consumption in male and female rats
    • Haynes AC, Jackson B, Chapman H, Tadayyon M, Johns A, et al. (2000) A selective orexin-1 receptor antagonist reduces food consumption in male and female rats. Regulatory Peptides 96: 45-51.
    • (2000) Regulatory Peptides , vol.96 , pp. 45-51
    • Haynes, A.C.1    Jackson, B.2    Chapman, H.3    Tadayyon, M.4    Johns, A.5
  • 42
    • 0003717437 scopus 로고    scopus 로고
    • The rat brain in stereotaxic coordinates
    • Amsterdam, Academic Press
    • Paxinos, G, Watson, C, (2007) The rat brain in stereotaxic coordinates. Amsterdam Academic Press.
    • (2007)
    • Paxinos, G.1    Watson, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.