The social defeat animal model of depression shows diminished levels of orexin in mesocortical regions of the dopamine system, and of dynorphin and orexin in the hypothalamus

Neuroscience

Volumn 218, Issue , 2012, Pages 138-153

  Nocjar, C ^a,b   Zhang, J ^c   Feng, P ^a,c   Panksepp, J ^d  

^a LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Anhedonia; Dynorphin; Hypothalamus; MPFC; Orexin; VTA

Indexed keywords

DYNORPHIN; OREXIN;

ANHEDONIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; BRAIN NERVE CELL; CONTROLLED STUDY; DEPRESSION; DOPAMINERGIC SYSTEM; HYPOTHALAMUS; MALE; MEDIAL PREFRONTAL CORTEX; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; RAT; SEXUAL BEHAVIOR; SOCIAL DEFEAT; SOCIAL STRESS; TISSUE DISTRIBUTION; VENTRAL TEGMENTUM;

ANHEDONIA; ANIMALS; BRAIN; DEPRESSION; DISEASE MODELS, ANIMAL; DOPAMINE; DYNORPHINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYPOTHALAMUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; NEUROPEPTIDES; PREFRONTAL CORTEX; RADIOIMMUNOASSAY; RATS; RATS, LONG-EVANS; VENTRAL TEGMENTAL AREA;

EID: 84863778971     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.05.033     Document Type: Article

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