-
1
-
-
44449113088
-
Physiological arousal: A role for hypothalamic systems
-
Adamantidis, A. de Lecea, L. (2008) Physiological arousal: a role for hypothalamic systems. Cell. Mol. Life Sci., 65, 1475 1488.
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 1475-1488
-
-
Adamantidis, A.1
De Lecea, L.2
-
2
-
-
19544390198
-
Hypocretins: Waking, arousal, or action?
-
Berridge, C.W. Espana, R.A. (2005) Hypocretins: waking, arousal, or action? Neuron, 46, 696 698.
-
(2005)
Neuron
, vol.46
, pp. 696-698
-
-
Berridge, C.W.1
Espana, R.A.2
-
3
-
-
64349107463
-
Biomedical Application of Orexin/Hypocretin Receptor Ligands in Neuroscience
-
Boss, C., Brisbare-Roch, C. Jenck, F. (2009) Biomedical Application of Orexin/Hypocretin Receptor Ligands in Neuroscience. J. Med. Chem., 52, 891 903.
-
(2009)
J. Med. Chem.
, vol.52
, pp. 891-903
-
-
Boss, C.1
Brisbare-Roch, C.2
Jenck, F.3
-
4
-
-
33846979755
-
Promotion of sleep by targeting the orexin system in rats, dogs and humans
-
DOI 10.1038/nm1544, PII NM1544
-
Brisbare-Roch, C., Dingemanse, J., Koberstein, R., Hoever, P., Aissaoui, H., Flores, S., Mueller, C., Nayler, O., van Gerven, J., de Haas, S.L., Hess, P., Qiu, C., Buchmann, S., Scherz, M., Weller, T., Fischli, W., Clozel, M. Jenck, F. (2007) Promotion of sleep by targeting the orexin system in rats, dogs and humans. Nat. Med., 13, 150 155. (Pubitemid 46245769)
-
(2007)
Nature Medicine
, vol.13
, Issue.2
, pp. 150-155
-
-
Brisbare-Roch, C.1
Dingemanse, J.2
Koberstein, R.3
Hoever, P.4
Aissaoui, H.5
Flores, S.6
Mueller, C.7
Nayler, O.8
Van Gerven, J.9
De Haas, S.L.10
Hess, P.11
Qiu, C.12
Buchmann, S.13
Scherz, M.14
Weller, T.15
Fischli, W.16
Clozel, M.17
Jenck, F.18
-
5
-
-
0035022676
-
Blood pressure, heart rate, and behavioral responses to psychological "novelty" stress in freely moving rats
-
van den Buuse, M., Van Acker, S.A., Fluttert, M. De Kloet, E.R. (2001) Blood pressure, heart rate, and behavioral responses to psychological "novelty" stress in freely moving rats. Psychophysiology, 38, 490 499.
-
(2001)
Psychophysiology
, vol.38
, pp. 490-499
-
-
Van Den Buuse, M.1
Van Acker, S.A.2
Fluttert, M.3
De Kloet, E.R.4
-
6
-
-
33845547801
-
Dual activation of cardiac sympathetic and parasympathetic components during conditioned fear to context in the rat
-
Carrive, P. (2006) Dual activation of cardiac sympathetic and parasympathetic components during conditioned fear to context in the rat. Clin. Exp. Pharmacol. Physiol., 33, 1251 1254.
-
(2006)
Clin. Exp. Pharmacol. Physiol.
, vol.33
, pp. 1251-1254
-
-
Carrive, P.1
-
7
-
-
47849129494
-
Premotor sympathetic neurons of conditioned fear in the rat
-
Carrive, P. Gorissen, M. (2008) Premotor sympathetic neurons of conditioned fear in the rat. Eur. J. Neurosci., 28, 428 446.
-
(2008)
Eur. J. Neurosci.
, vol.28
, pp. 428-446
-
-
Carrive, P.1
Gorissen, M.2
-
8
-
-
4243302729
-
Orexin (hypocretin) neurons contain dynorphin
-
Chou, T.C., Lee, C.E., Lu, J., Elmquist, J.K., Hara, J., Willie, J.T., Beuckmann, C.T., Chemelli, R.M., Sakurai, T., Yanagisawa, M., Saper, C.B. Scammell, T.E. (2001) Orexin (hypocretin) neurons contain dynorphin. J. Neurosci., 21, RC168.
-
(2001)
J. Neurosci.
, vol.21
, pp. 168
-
-
Chou, T.C.1
Lee, C.E.2
Lu, J.3
Elmquist, J.K.4
Hara, J.5
Willie, J.T.6
Beuckmann, C.T.7
Chemelli, R.M.8
Sakurai, T.9
Yanagisawa, M.10
Saper, C.B.11
Scammell, T.E.12
-
9
-
-
4143084917
-
The diurnal rhythm of hypocretin in young and old F344 rats
-
Desarnaud, F., Murillo-Rodriguez, E., Lin, L., Xu, M., Gerashchenko, D., Shiromani, S.N., Nishino, S., Mignot, E. Shiromani, P.J. (2004) The diurnal rhythm of hypocretin in young and old F344 rats. Sleep, 27, 851 856.
-
(2004)
Sleep
, vol.27
, pp. 851-856
-
-
Desarnaud, F.1
Murillo-Rodriguez, E.2
Lin, L.3
Xu, M.4
Gerashchenko, D.5
Shiromani, S.N.6
Nishino, S.7
Mignot, E.8
Shiromani, P.J.9
-
10
-
-
0142028210
-
Fos immunoreactivity in hypocretin-synthesizing and hypocretin-1 receptor-expressing neurons: Effects of diurnal and nocturnal spontaneous waking, stress and hypocretin-1 administration
-
Espana, R.A., Valentino, R.J. Berridge, C.W. (2003) Fos immunoreactivity in hypocretin-synthesizing and hypocretin-1 receptor-expressing neurons: effects of diurnal and nocturnal spontaneous waking, stress and hypocretin-1 administration. Neuroscience, 121, 201 217.
-
(2003)
Neuroscience
, vol.121
, pp. 201-217
-
-
Espana, R.A.1
Valentino, R.J.2
Berridge, C.W.3
-
11
-
-
0035282983
-
Fos expression in orexin neurons varies with behavioral state
-
Estabrooke, I.V., McCarthy, M.T., Ko, E., Chou, T.C., Chemelli, R.M., Yanagisawa, M., Saper, C.B. Scammell, T.E. (2001) Fos expression in orexin neurons varies with behavioral state. J. Neurosci., 21, 1656 1662.
-
(2001)
J. Neurosci.
, vol.21
, pp. 1656-1662
-
-
Estabrooke, I.V.1
McCarthy, M.T.2
Ko, E.3
Chou, T.C.4
Chemelli, R.M.5
Yanagisawa, M.6
Saper, C.B.7
Scammell, T.E.8
-
12
-
-
0035901736
-
Changes in CSF hypocretin-1 (orexin A) levels in rats across 24 hours and in response to food deprivation
-
Fujiki, N., Yoshida, Y., Ripley, B., Honda, K., Mignot, E. Nishino, S. (2001) Changes in CSF hypocretin-1 (orexin A) levels in rats across 24 hours and in response to food deprivation. Neuroreport, 12, 993 997.
-
(2001)
Neuroreport
, vol.12
, pp. 993-997
-
-
Fujiki, N.1
Yoshida, Y.2
Ripley, B.3
Honda, K.4
Mignot, E.5
Nishino, S.6
-
13
-
-
33845998148
-
Neurotoxic lesions centered on the perifornical hypothalamus abolish the cardiovascular and behavioral responses of conditioned fear to context but not of restraint
-
Furlong, T. Carrive, P. (2007) Neurotoxic lesions centered on the perifornical hypothalamus abolish the cardiovascular and behavioral responses of conditioned fear to context but not of restraint. Brain Res., 1128, 107 119.
-
(2007)
Brain Res.
, vol.1128
, pp. 107-119
-
-
Furlong, T.1
Carrive, P.2
-
14
-
-
0842299487
-
Relationship between CSF hypocretin levels and hypocretin neuronal loss
-
Gerashchenko, D., Murillo-Rodriguez, E., Lin, L., Xu, M., Hallett, L., Nishino, S., Mignot, E. Shiromani, P.J. (2003) Relationship between CSF hypocretin levels and hypocretin neuronal loss. Exp. Neurol., 184, 1010 1016.
-
(2003)
Exp. Neurol.
, vol.184
, pp. 1010-1016
-
-
Gerashchenko, D.1
Murillo-Rodriguez, E.2
Lin, L.3
Xu, M.4
Hallett, L.5
Nishino, S.6
Mignot, E.7
Shiromani, P.J.8
-
15
-
-
33748806552
-
Arousal and reward: A dichotomy in orexin function
-
Harris, G.C. Aston-Jones, G. (2006) Arousal and reward: a dichotomy in orexin function. Trends Neurosci., 29, 571 577.
-
(2006)
Trends Neurosci.
, vol.29
, pp. 571-577
-
-
Harris, G.C.1
Aston-Jones, G.2
-
16
-
-
17044398911
-
Detection of beta-endorphin in the cerebrospinal fluid after intrastriatal microinjection into the rat brain
-
Hoistad, M., Samskog, J., Jacobsen, K.X., Olsson, A., Hansson, H.A., Brodin, E. Fuxe, K. (2005) Detection of beta-endorphin in the cerebrospinal fluid after intrastriatal microinjection into the rat brain. Brain Res., 1041, 167 180.
-
(2005)
Brain Res.
, vol.1041
, pp. 167-180
-
-
Hoistad, M.1
Samskog, J.2
Jacobsen, K.X.3
Olsson, A.4
Hansson, H.A.5
Brodin, E.6
Fuxe, K.7
-
17
-
-
47249104297
-
Modulation of cortical activation and behavioral arousal by cholinergic and orexinergic systems
-
Jones, B.E. (2008) Modulation of cortical activation and behavioral arousal by cholinergic and orexinergic systems. Ann. N Y Acad. Sci., 1129, 26 34.
-
(2008)
Ann. N y Acad. Sci.
, vol.1129
, pp. 26-34
-
-
Jones, B.E.1
-
18
-
-
0041629653
-
Attenuated defense response and low basal blood pressure in orexin knockout mice
-
[see comment].
-
Kayaba, Y., Nakamura, A., Kasuya, Y., Ohuchi, T., Yanagisawa, M., Komuro, I., Fukuda, Y. Kuwaki, T. (2003) Attenuated defense response and low basal blood pressure in orexin knockout mice. [see comment]. Am. J. Physiol. Regul. Integr. Comp. Physiol., 285, R581 R593.
-
(2003)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.285
-
-
Kayaba, Y.1
Nakamura, A.2
Kasuya, Y.3
Ohuchi, T.4
Yanagisawa, M.5
Komuro, I.6
Fukuda, Y.7
Kuwaki, T.8
-
19
-
-
0036663072
-
Release of hypocretin (orexin) during waking and sleep states
-
Kiyashchenko, L.I., Mileykovskiy, B.Y., Maidment, N., Lam, H.A., Wu, M.-F., John, J., Peever, J. Siegel, J.M. (2002) Release of hypocretin (orexin) during waking and sleep states. J. Neurosci., 22, 5282 5286.
-
(2002)
J. Neurosci.
, vol.22
, pp. 5282-5286
-
-
Kiyashchenko, L.I.1
Mileykovskiy, B.Y.2
Maidment, N.3
Lam, H.A.4
Wu, M.-F.5
John, J.6
Peever, J.7
Siegel, J.M.8
-
20
-
-
14744280930
-
High Fos expression during the active phase in orexin neurons of a diurnal rodent, Tamias sibiricus barberi
-
Kodama, T., Usui, S., Honda, Y. Kimura, M. (2005) High Fos expression during the active phase in orexin neurons of a diurnal rodent, Tamias sibiricus barberi. Peptides, 26, 631 638.
-
(2005)
Peptides
, vol.26
, pp. 631-638
-
-
Kodama, T.1
Usui, S.2
Honda, Y.3
Kimura, M.4
-
21
-
-
22244443005
-
Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle
-
Lee, M.G., Hassani, O.K. Jones, B.E. (2005) Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle. J. Neurosci., 25, 6716 6720.
-
(2005)
J. Neurosci.
, vol.25
, pp. 6716-6720
-
-
Lee, M.G.1
Hassani, O.K.2
Jones, B.E.3
-
22
-
-
0037111492
-
Diurnal and nocturnal rodents show rhythms in orexinergic neurons
-
Martinez, G.S., Smale, L. Nunez, A.A. (2002) Diurnal and nocturnal rodents show rhythms in orexinergic neurons. Brain Res., 955, 1 7.
-
(2002)
Brain Res.
, vol.955
, pp. 1-7
-
-
Martinez, G.S.1
Smale, L.2
Nunez, A.A.3
-
23
-
-
1642471928
-
Increased hypocretin-1 (orexin-a) levels in cerebrospinal fluid of rats after short-term forced activity
-
Martins, P.J.F., D'Almeida, V., Pedrazzoli, M., Lin, L., Mignot, E. Tufik, S. (2004) Increased hypocretin-1 (orexin-a) levels in cerebrospinal fluid of rats after short-term forced activity. Regul. Pept., 117, 155 158.
-
(2004)
Regul. Pept.
, vol.117
, pp. 155-158
-
-
Martins, P.J.F.1
D'Almeida, V.2
Pedrazzoli, M.3
Lin, L.4
Mignot, E.5
Tufik, S.6
-
24
-
-
19544376694
-
Behavioral correlates of activity in identified hypocretin/orexin neurons
-
Mileykovskiy, B.Y., Kiyashchenko, L.I. Siegel, J.M. (2005) Behavioral correlates of activity in identified hypocretin/orexin neurons. Neuron, 46, 787 798.
-
(2005)
Neuron
, vol.46
, pp. 787-798
-
-
Mileykovskiy, B.Y.1
Kiyashchenko, L.I.2
Siegel, J.M.3
-
25
-
-
37549065569
-
Orexin neuronal circuitry: Role in the regulation of sleep and wakefulness
-
Ohno, K. Sakurai, T. (2008) Orexin neuronal circuitry: role in the regulation of sleep and wakefulness. Front. Neuroendocrinol., 29, 70 87.
-
(2008)
Front. Neuroendocrinol.
, vol.29
, pp. 70-87
-
-
Ohno, K.1
Sakurai, T.2
-
26
-
-
0027327545
-
Influence of autonomic blockade on cardiovascular responses to exercise in rats
-
Overton, J.M. (1993) Influence of autonomic blockade on cardiovascular responses to exercise in rats. J. Appl. Physiol., 75, 155 161.
-
(1993)
J. Appl. Physiol.
, vol.75
, pp. 155-161
-
-
Overton, J.M.1
-
27
-
-
0036815815
-
Orexins and appetite regulation
-
Rodgers, R.J., Ishii, Y., Halford, J.C.G. Blundell, J.E. (2002) Orexins and appetite regulation. Neuropeptides, 36, 303 325.
-
(2002)
Neuropeptides
, vol.36
, pp. 303-325
-
-
Rodgers, R.J.1
Ishii, Y.2
Halford, J.C.G.3
Blundell, J.E.4
-
28
-
-
0141593423
-
Hypothalamic orexin (hypocretin) neurons express vesicular glutamate transporters VGLUT1 or VGLUT2
-
Rosin, D.L., Weston, M.C., Sevigny, C.P., Stornetta, R.L. Guyenet, P.G. (2003) Hypothalamic orexin (hypocretin) neurons express vesicular glutamate transporters VGLUT1 or VGLUT2. J. Comp. Neurol., 465, 593 603.
-
(2003)
J. Comp. Neurol.
, vol.465
, pp. 593-603
-
-
Rosin, D.L.1
Weston, M.C.2
Sevigny, C.P.3
Stornetta, R.L.4
Guyenet, P.G.5
-
29
-
-
1542270814
-
Centrally administered orexin-A activates corticotropin-releasing factor-containing neurons in the hypothalamic paraventricular nucleus and central amygdaloid nucleus of rats: Possible involvement of central orexins on stress-activated central CRF neurons
-
Sakamoto, F., Yamada, S. Ueta, Y. (2004) Centrally administered orexin-A activates corticotropin-releasing factor-containing neurons in the hypothalamic paraventricular nucleus and central amygdaloid nucleus of rats: possible involvement of central orexins on stress-activated central CRF neurons. Regul. Pept., 118, 183 191.
-
(2004)
Regul. Pept.
, vol.118
, pp. 183-191
-
-
Sakamoto, F.1
Yamada, S.2
Ueta, Y.3
-
30
-
-
0032489093
-
Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
-
Sakurai, T., Amemiya, A., Ishii, M., Matsuzaki, I., Chemelli, R.M., Tanaka, H., Williams, S.C., Richardson, J.A., Kozlowski, G.P., Wilson, S., Arch, J.R., Buckingham, R.E., Haynes, A.C., Carr, S.A., Annan, R.S., McNulty, D.E., Liu, W.S., Terrett, J.A., Elshourbagy, N.A., Bergsma, D.J. Yanagisawa, M. (1998) Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell, 92, 573 585.
-
(1998)
Cell
, vol.92
, pp. 573-585
-
-
Sakurai, T.1
Amemiya, A.2
Ishii, M.3
Matsuzaki, I.4
Chemelli, R.M.5
Tanaka, H.6
Williams, S.C.7
Richardson, J.A.8
Kozlowski, G.P.9
Wilson, S.10
Arch, J.R.11
Buckingham, R.E.12
Haynes, A.C.13
Carr, S.A.14
Annan, R.S.15
McNulty, D.E.16
Liu, W.S.17
Terrett, J.A.18
Elshourbagy, N.A.19
Bergsma, D.J.20
Yanagisawa, M.21
more..
-
31
-
-
20244374121
-
Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice. [Erratum appears in Neuron. 2005 Jun 2; 46(5):837]
-
Sakurai, T., Nagata, R., Yamanaka, A., Kawamura, H., Tsujino, N., Muraki, Y., Kageyama, H., Kunita, S., Takahashi, S., Goto, K., Koyama, Y., Shioda, S. Yanagisawa, M. (2005) Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice. [Erratum appears in Neuron. 2005 Jun 2; 46(5):837]. Neuron, 46, 297 308.
-
(2005)
Neuron
, vol.46
, pp. 297-308
-
-
Sakurai, T.1
Nagata, R.2
Yamanaka, A.3
Kawamura, H.4
Tsujino, N.5
Muraki, Y.6
Kageyama, H.7
Kunita, S.8
Takahashi, S.9
Goto, K.10
Koyama, Y.11
Shioda, S.12
Yanagisawa, M.13
-
32
-
-
27644457084
-
Hypothalamic regulation of sleep and circadian rhythms
-
DOI 10.1038/nature04284, PII N04284
-
Saper, C.B., Scammell, T.E. Lu, J. (2005) Hypothalamic regulation of sleep and circadian rhythms. Nature, 437, 1257 1263. (Pubitemid 41568665)
-
(2005)
Nature
, vol.437
, Issue.7063
, pp. 1257-1263
-
-
Saper, C.B.1
Scammell, T.E.2
Lu, J.3
-
33
-
-
0033550883
-
Feeding response to central orexins
-
Sweet, D.C., Levine, A.S., Billington, C.J. Kotz, C.M. (1999) Feeding response to central orexins. Brain Res., 821, 535 538.
-
(1999)
Brain Res.
, vol.821
, pp. 535-538
-
-
Sweet, D.C.1
Levine, A.S.2
Billington, C.J.3
Kotz, C.M.4
-
34
-
-
0037840864
-
Hypocretinergic neurons are primarily involved in activation of the somatomotor system
-
Torterolo, P., Yamuy, J., Sampogna, S., Morales, F.R. Chase, M.H. (2003) Hypocretinergic neurons are primarily involved in activation of the somatomotor system. Sleep, 26, 25 28.
-
(2003)
Sleep
, vol.26
, pp. 25-28
-
-
Torterolo, P.1
Yamuy, J.2
Sampogna, S.3
Morales, F.R.4
Chase, M.H.5
-
35
-
-
43949087487
-
Cardiovascular and behavioral responses to conditioned fear after medullary raphe neuronal blockade
-
Vianna, D.M., Allen, C. Carrive, P. (2008) Cardiovascular and behavioral responses to conditioned fear after medullary raphe neuronal blockade. Neuroscience, 153, 1344 1353.
-
(2008)
Neuroscience
, vol.153
, pp. 1344-1353
-
-
Vianna, D.M.1
Allen, C.2
Carrive, P.3
-
36
-
-
0037450438
-
Role of ventrolateral periaqueductal gray neurons in the behavioral and cardiovascular responses to contextual conditioned fear and poststress recovery
-
DOI 10.1016/S0306-4522(02)00744-3
-
Walker, P. Carrive, P. (2003) Role of ventrolateral periaqueductal gray neurons in the behavioral and cardiovascular responses to contextual conditioned fear and poststress recovery. Neuroscience, 116, 897 912. (Pubitemid 36160582)
-
(2003)
Neuroscience
, vol.116
, Issue.3
, pp. 897-912
-
-
Walker, P.1
Carrive, P.2
-
37
-
-
10644267749
-
Interaction between the corticotropin-releasing factor system and hypocretins (orexins): A novel circuit mediating stress response
-
Winsky-Sommerer, R., Yamanaka, A., Diano, S., Borok, E., Roberts, A.J., Sakurai, T., Kilduff, T.S., Horvath, T.L. de Lecea, L. (2004) Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response. J. Neurosci., 24, 11439 11448.
-
(2004)
J. Neurosci.
, vol.24
, pp. 11439-11448
-
-
Winsky-Sommerer, R.1
Yamanaka, A.2
Diano, S.3
Borok, E.4
Roberts, A.J.5
Sakurai, T.6
Kilduff, T.S.7
Horvath, T.L.8
De Lecea, L.9
-
38
-
-
30144433306
-
Afferents to the orexin neurons of the rat brain
-
Yoshida, K., McCormack, S., Espana, R.A., Crocker, A. Scammell, T.E. (2006) Afferents to the orexin neurons of the rat brain. J. Comp. Neurol., 494, 845 861.
-
(2006)
J. Comp. Neurol.
, vol.494
, pp. 845-861
-
-
Yoshida, K.1
McCormack, S.2
Espana, R.A.3
Crocker, A.4
Scammell, T.E.5
-
39
-
-
33744523416
-
Multiple components of the defense response depend on orexin: Evidence from orexin knockout mice and orexin neuron-ablated mice
-
Zhang, W., Shimoyama, M., Fukuda, Y. Kuwaki, T. (2006) Multiple components of the defense response depend on orexin: evidence from orexin knockout mice and orexin neuron-ablated mice. Auton. Neurosci., 126-127, 139 145.
-
(2006)
Auton. Neurosci.
, vol.126-127
, pp. 139-145
-
-
Zhang, W.1
Shimoyama, M.2
Fukuda, Y.3
Kuwaki, T.4
|