Tissue-nonspecific alkaline phosphatase deficiency causes abnormal craniofacial bone development in the Alpl-/- mouse model of infantile hypophosphatasia

Bone

Volumn 67, Issue , 2014, Pages 81-94

  Liu, Jin ^a   Nam, Hwa Kyung ^a   Campbell, Cassie ^a   Gasque, Kellen Cristina da Silva ^b   Millán, José Luis ^b   Hatch, Nan E ^a  

^a UNIVERSITY OF MICHIGAN SCHOOL OF DENTISTRY   (United States)

^b BURNHAM INSTITUTE   (United States)

Author keywords

Animal models; Bone; Craniofacial; Disorders of phosphate; Micro CT ( CT)

Indexed keywords

ALKALINE PHOSPHATASE; SHORT HAIRPIN RNA; TISSUE NONSPECIFIC ALKALINE PHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE CELL; BONE DEMINERALIZATION; CALVARIA; CELL ADHESION; CELL PROLIFERATION; CONTROLLED STUDY; CORTICAL BONE; CRANIOFACIAL SYNOSTOSIS; DISEASE ASSOCIATION; DOWN REGULATION; ENZYME DEFICIENCY; ENZYME SPECIFICITY; GENE EXPRESSION; GROWTH PLATE; HISTOPATHOLOGY; HYPOPHOSPHATASIA; INFANTILE HYPOPHOSPHATASIA; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NEUROANATOMY; NEUROIMAGING; NONHUMAN; PROTEIN EXPRESSION; TRABECULAR BONE; ANIMAL; CELL LINE; CRANIOFACIAL MALFORMATION; DISEASE MODEL; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY;

ALKALINE PHOSPHATASE; ANIMALS; CELL LINE; CRANIOFACIAL ABNORMALITIES; CRANIOSYNOSTOSES; DISEASE MODELS, ANIMAL; HYPOPHOSPHATASIA; MICE; MICE, KNOCKOUT;

EID: 84904511967     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2014.06.040     Document Type: Article

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