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Volumn 207, Issue 5, 2005, Pages 637-653

Growth of the normal skull vault and its alteration in craniosynostosis: Insights from human genetics and experimental studies

Author keywords

Cranial sutures; Efnbl; Fibroblast growth factor receptors; Msx2; Neural crest; Osteoprogenitor cells; Twist1

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 3; GENE PRODUCT; PROTEIN EFNB1; TRANSCRIPTION FACTOR MSX2; TRANSCRIPTION FACTOR TWIST; TRANSCRIPTION FACTOR TWIST1; UNCLASSIFIED DRUG;

EID: 28444453646     PISSN: 00218782     EISSN: 14697580     Source Type: Journal    
DOI: 10.1111/j.1469-7580.2005.00475.x     Document Type: Review
Times cited : (374)

References (96)
  • 1
    • 0031683688 scopus 로고    scopus 로고
    • Apert syndrome mutations in fibroblast growth factor receptor 2 exhibit increased affinity for FGF ligand
    • Anderson J, Burns HD, Enriquez-Harris P, Wilkie AOM, Heath JK (1998) Apert syndrome mutations in fibroblast growth factor receptor 2 exhibit increased affinity for FGF ligand. Hum Mol Genet 7, 1475-1483.
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 1475-1483
    • Anderson, J.1    Burns, H.D.2    Enriquez-Harris, P.3    Wilkie, A.O.M.4    Heath, J.K.5
  • 2
    • 0032574824 scopus 로고    scopus 로고
    • Targeted disruption of FGFR2 suggests a role for FGF signalling in pre-gastrulation mammalian development
    • Arman E, Haffner-Krausz R, Chen Y, Heath JK, Lonai P (1998) Targeted disruption of FGFR2 suggests a role for FGF signalling in pre-gastrulation mammalian development. Proc Natl Acad Sci USA 95, 5082-5087.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5082-5087
    • Arman, E.1    Haffner-Krausz, R.2    Chen, Y.3    Heath, J.K.4    Lonai, P.5
  • 3
    • 0034717168 scopus 로고    scopus 로고
    • Fibroblast growth factor (FGF) receptor 1-IIIb is a naturally occurring functional receptor for FGfs that is preferentially expressed in the skin and brain
    • Beer HD, Vindevoghel L, Gait MJ, et al. (2000) Fibroblast growth factor (FGF) receptor 1-IIIb is a naturally occurring functional receptor for FGfs that is preferentially expressed in the skin and brain. J Biol Chem 275, 16091-16097.
    • (2000) J. Biol. Chem. , vol.275 , pp. 16091-16097
    • Beer, H.D.1    Vindevoghel, L.2    Gait, M.J.3
  • 4
    • 0029845996 scopus 로고    scopus 로고
    • Heartless, a Drosophila FGF receptor homolog, is essential for cell migration and establishment of several mesodermal lineages
    • Beiman M, Shilo BZ, Volk T (1996) Heartless, a Drosophila FGF receptor homolog, is essential for cell migration and establishment of several mesodermal lineages. Genes Dev 10, 2993-3002.
    • (1996) Genes Dev. , vol.10 , pp. 2993-3002
    • Beiman, M.1    Shilo, B.Z.2    Volk, T.3
  • 5
    • 0029798614 scopus 로고    scopus 로고
    • Identical mutations in three different fibroblast growth factor receptor genes in autosomal dominant craniosynostosis syndromes
    • Bellus GA, Gaudenz K, Zackai EH, et al. (1996) Identical mutations in three different fibroblast growth factor receptor genes in autosomal dominant craniosynostosis syndromes. Nature Genet 14, 174-176.
    • (1996) Nature Genet. , vol.14 , pp. 174-176
    • Bellus, G.A.1    Gaudenz, K.2    Zackai, E.H.3
  • 7
    • 12144288066 scopus 로고    scopus 로고
    • A Twist code determines the onset of osteoblast differentiation
    • Bialek P, Kern B, Yang X, et al. (2004) A Twist code determines the onset of osteoblast differentiation. Dev Cell 6, 423-435.
    • (2004) Dev. Cell , vol.6 , pp. 423-435
    • Bialek, P.1    Kern, B.2    Yang, X.3
  • 8
    • 0031832127 scopus 로고    scopus 로고
    • The variable expressivity and incomplete penetrance of the twistnull heterozygous mouse phenotype resemble those of human Saethre-Chotzen syndrome
    • Bourgeois P, Bolcato-Bellemin AL, Danse JM, et al. (1998) The variable expressivity and incomplete penetrance of the twistnull heterozygous mouse phenotype resemble those of human Saethre-Chotzen syndrome. Hum Mol Genet 7, 945-957.
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 945-957
    • Bourgeois, P.1    Bolcato-Bellemin, A.L.2    Danse, J.M.3
  • 9
    • 0029913530 scopus 로고    scopus 로고
    • Studies in cranial suture biology. IV. Temporal sequence of posterior frontal cranial suture fusion in the mouse
    • Bradley JP, Levine JP, Roth DA, McCarthy JG, Longaker MT (1996) Studies in cranial suture biology. IV. Temporal sequence of posterior frontal cranial suture fusion in the mouse. Plast Reconstr Surg 98, 1039-1045.
    • (1996) Plast. Reconstr. Surg. , vol.98 , pp. 1039-1045
    • Bradley, J.P.1    Levine, J.P.2    Roth, D.A.3    McCarthy, J.G.4    Longaker, M.T.5
  • 10
    • 0036788297 scopus 로고    scopus 로고
    • Craniosynostosis in Twist heterozygous mice: A model for Saethre-Chotzen syndrome
    • Carver EA, Oram KF, Gridley T (2002) Craniosynostosis in Twist heterozygous mice: a model for Saethre-Chotzen syndrome. Anat Rec 268, 90-92.
    • (2002) Anat. Rec. , vol.268 , pp. 90-92
    • Carver, E.A.1    Oram, K.F.2    Gridley, T.3
  • 12
    • 0023832833 scopus 로고
    • A morphological and experimental study of the mesencephalic neural crest cells in the mouse embryo using wheat germ agglutinin-gold conjugate as the cell marker
    • Chan WY, Tam PPL (1988) A morphological and experimental study of the mesencephalic neural crest cells in the mouse embryo using wheat germ agglutinin-gold conjugate as the cell marker. Development 102, 427-442.
    • (1988) Development , vol.102 , pp. 427-442
    • Chan, W.Y.1    Tam, P.P.L.2
  • 13
    • 0141678494 scopus 로고    scopus 로고
    • A Series 250Trp substitution in mouse fibroblast growth factor receptor 2 (Fgfr2) results in craniosynostosis
    • Chen L, Li D, Li C, Engl A, Deng CX (2003) A Series 250Trp substitution in mouse fibroblast growth factor receptor 2 (Fgfr2) results in craniosynostosis. Bone 33, 169-178.
    • (2003) Bone , vol.33 , pp. 169-178
    • Chen, L.1    Li, D.2    Li, C.3    Engl, A.4    Deng, C.X.5
  • 14
    • 0028933142 scopus 로고
    • Twist is required in head mesenchyme for cranial neural tube morphogenesis
    • Chen ZF, Behringer RR (1995) Twist is required in head mesenchyme for cranial neural tube morphogenesis. Genes Dev 9, 686-699.
    • (1995) Genes Dev. , vol.9 , pp. 686-699
    • Chen, Z.F.1    Behringer, R.R.2
  • 15
    • 0033961810 scopus 로고    scopus 로고
    • Daar IO Fibroblast growth factor receptor-mediated rescue of x-ephrin B1-induced cell dissociation in Xenopus embryos
    • Chong LD, Park EK, Latimer E, Friesel R, Daar IO (2000) Fibroblast growth factor receptor-mediated rescue of x-ephrin B1-induced cell dissociation in Xenopus embryos. Mol Cell Biol 20, 724-734.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 724-734
    • Chong, L.D.1    Park, E.K.2    Latimer, E.3    Friesel, R.4
  • 16
    • 0018636142 scopus 로고
    • Craniofrontonasal dysplasia
    • Cohen MM Jr (1979) Craniofrontonasal dysplasia. Birth Defects 15 (5B), 85-89.
    • (1979) Birth Defects , vol.15 , Issue.5 B , pp. 85-89
    • Cohen Jr., M.M.1
  • 17
    • 0000559015 scopus 로고    scopus 로고
    • Epidemiology of craniosynostosis
    • (eds Cohen MM Jr, MacLean RE), 2nd edition, New York: Oxford University Press
    • Cohen MM Jr (2000) Epidemiology of craniosynostosis. In Craniosynostosis (eds Cohen MM Jr, MacLean RE), 2nd edition, pp. 112-118. New York: Oxford University Press.
    • (2000) Craniosynostosis , pp. 112-118
    • Cohen Jr., M.M.1
  • 18
    • 0029928791 scopus 로고    scopus 로고
    • Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3
    • Colvin JS, Bohne BA, Harding GW, McEwan DG, Ornitz DM (1996) Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3. Nat Genet 12, 390-397.
    • (1996) Nat. Genet. , vol.12 , pp. 390-397
    • Colvin, J.S.1    Bohne, B.A.2    Harding, G.W.3    McEwan, D.G.4    Ornitz, D.M.5
  • 19
    • 0042442460 scopus 로고    scopus 로고
    • Control of skeletal patterning by ephrinB1-EphB interactions
    • Compagni A, Logan M, Klein R, Adams RH (2003) Control of skeletal patterning by ephrinB1-EphB interactions. Dev Cell 5, 217-230.
    • (2003) Dev. Cell , vol.5 , pp. 217-230
    • Compagni, A.1    Logan, M.2    Klein, R.3    Adams, R.H.4
  • 21
    • 0036744679 scopus 로고    scopus 로고
    • Negative effect of Hox gene expression on the development of the neural crest-derived facial skeleton
    • Creuzet S, Couly G, Vincent C, le Douarin NM (2002) Negative effect of Hox gene expression on the development of the neural crest-derived facial skeleton. Development 129, 4301-4313.
    • (2002) Development , vol.129 , pp. 4301-4313
    • Creuzet, S.1    Couly, G.2    Vincent, C.3    le Douarin, N.M.4
  • 22
    • 0029917507 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 is a negative regulator of bone growth
    • Deng C, Wynshaw-Boris A, Zhou F, Kuo A, Leder P (1996) Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell 84, 911-921.
    • (1996) Cell , vol.84 , pp. 911-921
    • Deng, C.1    Wynshaw-Boris, A.2    Zhou, F.3    Kuo, A.4    Leder, P.5
  • 23
    • 0031012353 scopus 로고    scopus 로고
    • Mutations of the TWIST gene in the Saethre-Chotzen syndrome
    • El Ghouzzi V, LeMerrer M, Perrin-Schmidt F, et al. (1997) Mutations of the TWIST gene in the Saethre-Chotzen syndrome. Nat Genet 15, 42-46.
    • (1997) Nat. Genet. , vol.15 , pp. 42-46
    • El Ghouzzi, V.1    LeMerrer, M.2    Perrin-Schmidt, F.3
  • 24
    • 0035831060 scopus 로고    scopus 로고
    • Mutations in the basic domain and the loop-helix II junction of TWIST abolish DNA binding in Saethre-Chotzen syndrome
    • El Ghouzzi V, Legeai-Mallet L, Benoist-Lasselin C, et al. (2001) Mutations in the basic domain and the loop-helix II junction of TWIST abolish DNA binding in Saethre-Chotzen syndrome. FEBS Lett 492, 112-118.
    • (2001) FEBS Lett. , vol.492 , pp. 112-118
    • El Ghouzzi, V.1    Legeai-Mallet, L.2    Benoist-Lasselin, C.3
  • 27
    • 0026551603 scopus 로고
    • Migration of cranial neural crest cells to the pharyngeal arches and heart in rat embryos
    • Fukiishi Y, Morriss-Kay GM (1992) Migration of cranial neural crest cells to the pharyngeal arches and heart in rat embryos. Cell Tissue Res 268, 1-8.
    • (1992) Cell Tissue Res. , vol.268 , pp. 1-8
    • Fukiishi, Y.1    Morriss-Kay, G.M.2
  • 29
    • 20444448111 scopus 로고    scopus 로고
    • A role for fibroblast growth factor receptor-2 in the altered osteoblast phenotype induced by Twist haploinsufficiency in the Saethre-Chotzen syndrome
    • Guenou H, Kaabeche K, Le Mée S, Marie PJ (2005) A role for fibroblast growth factor receptor-2 in the altered osteoblast phenotype induced by Twist haploinsufficiency in the Saethre-Chotzen syndrome. Hum Mol Genet 14, 1429-1439.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 1429-1439
    • Guenou, H.1    Kaabeche, K.2    Le Mée, S.3    Marie, P.J.4
  • 30
    • 0035957343 scopus 로고    scopus 로고
    • A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer syndrome-like phenotypes
    • Hajihosseini MK, Wilson S, De Moerlooze L, Dickson C (2001) A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer syndrome-like phenotypes. Proc Natl Acad Sci USA 98, 3641-3643.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 3641-3643
    • Hajihosseini, M.L.K.1    Wilson, S.2    De Moerlooze, L.3    Dickson, C.4
  • 31
    • 0036126130 scopus 로고    scopus 로고
    • Expression patterns of fibroblast growth factors-18 and -20 in mouse embryos is suggestive of novel roles in calvarial and limb development
    • Hajihosseini MK, Heath JK (2002) Expression patterns of fibroblast growth factors-18 and -20 in mouse embryos is suggestive of novel roles in calvarial and limb development. Mech Dev 113, 79-83.
    • (2002) Mech. Dev. , vol.113 , pp. 79-83
    • Hajihosseini, M.K.1    Heath, J.K.2
  • 33
    • 0842330738 scopus 로고    scopus 로고
    • Sutural bone deposition rate and strain magnitude during cranial development
    • Henderson JH, Longaker MT, Carter DR (2004) Sutural bone deposition rate and strain magnitude during cranial development. Bone 34, 271-280.
    • (2004) Bone , vol.34 , pp. 271-280
    • Henderson, J.H.1    Longaker, M.T.2    Carter, D.R.3
  • 34
    • 0031021336 scopus 로고    scopus 로고
    • Mutations in TWIST, a basic helix-loop-helix transcription factor, in Saethre-Chotzen syndrome
    • Howard TD, Paznekas WA, Green ED, et al. (1997) Mutations in TWIST, a basic helix-loop-helix transcription factor, in Saethre-Chotzen syndrome. Nat Genet 15, 36-41.
    • (1997) Nat. Genet. , vol.15 , pp. 36-41
    • Howard, T.D.1    Paznekas, W.A.2    Green, E.D.3
  • 35
    • 0347287038 scopus 로고    scopus 로고
    • Proline to arginine mutations in FGF receptors 1 and 3 result in Pfeiffer and Muenke cranio-synostosis syndromes through enhancement of FGF binding affinity
    • Ibrahimi OA, Zhang F, Eliseenkova AV, Linhardt RJ, Mohammadi M (2004a) Proline to arginine mutations in FGF receptors 1 and 3 result in Pfeiffer and Muenke cranio-synostosis syndromes through enhancement of FGF binding affinity. Hum Mol Genet 13, 69-78.
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 69-78
    • Ibrahimi, O.A.1    Zhang, F.2    Eliseenkova, A.V.3    Linhardt, R.J.4    Mohammadi, M.5
  • 36
    • 5444250989 scopus 로고    scopus 로고
    • Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities
    • Ibrahimi OA, Zhang F, Eliseenkova AV, Itoh N, Linhardt RJ, Mohammadi M (2004b) Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities. Hum Mol Genet 13, 2313-2324.
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 2313-2324
    • Ibrahimi, O.A.1    Zhang, F.2    Eliseenkova, A.V.3    Itoh, N.4    Linhardt, R.J.5    Mohammadi, M.6
  • 37
    • 0030833319 scopus 로고    scopus 로고
    • Fgfr2 and osteopontin domains in the developing skull vault are mutually exclusive and can be altered by locally applied FGF2
    • Iseki S, Wilkie AOM, Heath JK, Ishimaru T, Eto K, Morriss-Kay GM (1997) Fgfr2 and osteopontin domains in the developing skull vault are mutually exclusive and can be altered by locally applied FGF2. Development 124, 3375-3384.
    • (1997) Development , vol.124 , pp. 3375-3384
    • Iseki, S.1    Wilkie, A.O.M.2    Heath, J.K.3    Ishimaru, T.4    Eto, K.5    Morriss-Kay, G.M.6
  • 38
    • 0033373550 scopus 로고    scopus 로고
    • Fqfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault
    • Iseki S, Wilkie AOM, Morriss-Kay GM (1999) Fqfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault. Development 126, 5611-5620.
    • (1999) Development , vol.126 , pp. 5611-5620
    • Iseki, S.1    Wilkie, A.O.M.2    Morriss-Kay, G.M.3
  • 39
    • 28444481801 scopus 로고    scopus 로고
    • Mouse skull vault bones grow by expanding of their primordia and Bmps are involved in this process
    • in press
    • Iseki S, Yoshida T, Ishikawa I, Eto K (2005) Mouse skull vault bones grow by expanding of their primordia and Bmps are involved in this process. J Anat 207, in press.
    • (2005) J. Anat. , vol.207
    • Iseki, S.1    Yoshida, T.2    Ishikawa, I.3    Eto, K.4
  • 40
    • 0346252654 scopus 로고    scopus 로고
    • Msx2 and Twist cooperatively control the development of the neural crest-derived skeletogenic mesenchyme of the murine skull vault
    • Ishii M, Merrill AE, Chan YS, et al. (2003) Msx2 and Twist cooperatively control the development of the neural crest-derived skeletogenic mesenchyme of the murine skull vault. Development 130, 6131-6142.
    • (2003) Development , vol.130 , pp. 6131-6142
    • Ishii, M.1    Merrill, A.E.2    Chan, Y.S.3
  • 41
    • 4744372082 scopus 로고    scopus 로고
    • Evolution of the Fgf and Fgfr gene families
    • Itoh N, Ornitz DM (2004) Evolution of the Fgf and Fgfr gene families. Trends Genet 20, 563-569.
    • (2004) Trends Genet. , vol.20 , pp. 563-569
    • Itoh, N.1    Ornitz, D.M.2
  • 42
    • 0027431005 scopus 로고
    • A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis
    • Jabs EW, Muller U, Li X, et al. (1993) A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis. Cell 75, 443-450.
    • (1993) Cell , vol.75 , pp. 443-450
    • Jabs, E.W.1    Muller, U.2    Li, X.3
  • 45
    • 0027344852 scopus 로고
    • Structural and functional diversity of the FGF receptor multigene family
    • Johnson DE, Williams LT (1993) Structural and functional diversity of the FGF receptor multigene family. Ad Cancer Res 60, 1-41.
    • (1993) Ad. Cancer Res. , vol.60 , pp. 1-41
    • Johnson, D.E.1    Williams, L.T.2
  • 46
    • 0034002459 scopus 로고    scopus 로고
    • Expression patterns of Twist and Fgfr1-2 and -3 in the developing mouse coronal suture suggest a key role for Twist in suture initiation and biogenesis
    • Johnson D, Iseki I, Wilkie AOM, Morriss-Kay GM (2000) Expression patterns of Twist and Fgfr1-2 and -3 in the developing mouse coronal suture suggest a key role for Twist in suture initiation and biogenesis. Mech Dev 91, 341-345.
    • (2000) Mech. Dev. , vol.91 , pp. 341-345
    • Johnson, D.1    Iseki, I.2    Wilkie, A.O.M.3    Morriss-Kay, G.M.4
  • 47
    • 0020640517 scopus 로고
    • Neural crest cells contribute to aorticopulmonary septation
    • Kirby ML, Gale TF, Stewart DE (1983) Neural crest cells contribute to aorticopulmonary septation. Science 220, 1059-1061.
    • (1983) Science , vol.220 , pp. 1059-1061
    • Kirby, M.L.1    Gale, T.F.2    Stewart, D.E.3
  • 48
    • 0027413198 scopus 로고
    • Hox genes and pattern formation in the branchial region of the vertebrate head
    • Krumlauf R (1993) Hox genes and pattern formation in the branchial region of the vertebrate head. Trends Genet 9, 106-112.
    • (1993) Trends Genet. , vol.9 , pp. 106-112
    • Krumlauf, R.1
  • 49
    • 0026494353 scopus 로고
    • Clonal analysis of cell fate during gastrulation and early neurulation in the mouse
    • Lawson KA, Pedersen RA (1992) Clonal analysis of cell fate during gastrulation and early neurulation in the mouse. Ciba Fnd Symp 165, 3-21.
    • (1992) Ciba Fnd. Symp. , vol.165 , pp. 3-21
    • Lawson, K.A.1    Pedersen, R.A.2
  • 50
    • 0036203355 scopus 로고    scopus 로고
    • Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18
    • Liu Z, Xu J, Colvin JS, Ornitz DJ (2002) Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. Genes Dev 16, 859-869.
    • (2002) Genes Dev. , vol.16 , pp. 859-869
    • Liu, Z.1    Xu, J.2    Colvin, J.S.3    Ornitz, D.J.4
  • 51
    • 20144367207 scopus 로고    scopus 로고
    • A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or Tgfbr2
    • Loeys BL, Chen J, Neptune ER, et al. (2005) A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or Tgfbr2. Nat Genet 37, 275-279.
    • (2005) Nat. Genet. , vol.37 , pp. 275-279
    • Loeys, B.L.1    Chen, J.2    Neptune, E.R.3
  • 52
    • 0029800845 scopus 로고    scopus 로고
    • The molecular basis of Boston-type craniosynostosis: The Pro148-His mutation in the N-terminal arm of the MSX2 homeodomain stabilises DNA binding without altering nucleotide sequence preferences
    • Ma L, Golden S, Wu L, Maxson R (1996) The molecular basis of Boston-type craniosynostosis: the Pro148-His mutation in the N-terminal arm of the MSX2 homeodomain stabilises DNA binding without altering nucleotide sequence preferences. Hum Mol Genet 5, 1915-1920.
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 1915-1920
    • Ma, L.1    Golden, S.2    Wu, L.3    Maxson, R.4
  • 54
    • 0026570847 scopus 로고
    • Determination of ligand-binding specificity by alternative splicing: Two distinct growth factor receptors encoded by a single gene
    • Miki T, Bottaro DP, Fleming TP, et al. (1992) Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene. Proc Natl Acad Sci USA 89, 246-250.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 246-250
    • Miki, T.1    Bottaro, D.P.2    Fleming, T.P.3
  • 55
    • 0346503239 scopus 로고    scopus 로고
    • Morphogenetic movements underlying eye field formation require interactions between the FGF and ephrinB1 signalling pathways
    • Moore KB, Mood K, Daar IO, Moody SA (2004) Morphogenetic movements underlying eye field formation require interactions between the FGF and ephrinB1 signalling pathways. Dev Cell 6, 55-67.
    • (2004) Dev. Cell , vol.6 , pp. 55-67
    • Moore, K.B.1    Mood, K.2    Daar, I.O.3    Moody, S.A.4
  • 56
    • 0022924541 scopus 로고
    • The effects of Streptomyces hyaluronidase on tissue organization and cell cycle time in rat embryos
    • Morriss-Kay GM, Tuckett F, Solursh M (1986) The effects of Streptomyces hyaluronidase on tissue organization and cell cycle time in rat embryos. J Embryol Exp Morph 98, 57-70.
    • (1986) J. Embryol. Exp. Morph. , vol.98 , pp. 57-70
    • Morriss-Kay, G.M.1    Tuckett, F.2    Solursh, M.3
  • 57
    • 0028046606 scopus 로고
    • A common mutation in the fibroblast growth factor receptor 1 gene in Pfeiffer syndrome
    • Muenke M, Schell U, Hehr A, et al. (1994) A common mutation in the fibroblast growth factor receptor 1 gene in Pfeiffer syndrome. Nat Genet 8, 269-274.
    • (1994) Nat. Genet. , vol.8 , pp. 269-274
    • Muenke, M.1    Schell, U.2    Hehr, A.3
  • 58
    • 0028846512 scopus 로고
    • Constitutive activation of fibroblast growth factor receptor-2 by a point mutation associated with Crouzon syndrome
    • Neilson KM, Friesel RE (1995) Constitutive activation of fibroblast growth factor receptor-2 by a point mutation associated with Crouzon syndrome. J Biol Chem 270, 26037-26040.
    • (1995) J. Biol. Chem. , vol.270 , pp. 26037-26040
    • Neilson, K.M.1    Friesel, R.E.2
  • 59
    • 0036205735 scopus 로고    scopus 로고
    • FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis
    • Ohbayashi N, Shibayama M, Kurotaki Y, et al. (2002) FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev 16, 870-879.
    • (2002) Genes Dev. , vol.16 , pp. 870-879
    • Ohbayashi, N.1    Shibayama, M.2    Kurotaki, Y.3
  • 60
    • 0033073850 scopus 로고    scopus 로고
    • De novo Alu element insertions in FGFR2 identify a distinct pathological basis for Apert syndrome
    • Oldridge M, McDonald-McGinn DM, Iseki S, et al. (1999) De novo Alu element insertions in FGFR2 identify a distinct pathological basis for Apert syndrome. Am J Hum Genet 64, 446-461.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 446-461
    • Oldridge, M.1    McDonald-McGinn, D.M.2    Iseki, S.3
  • 61
    • 0033778791 scopus 로고    scopus 로고
    • Transforming growth factor-beta 2 and TGF-beta 3 regulate fetal rat cranial suture morphogenesis by regulating rates of cell proliferation and apoptosis
    • Opperman LA, Adab K, Gakunga PT (2000) Transforming growth factor-beta 2 and TGF-beta 3 regulate fetal rat cranial suture morphogenesis by regulating rates of cell proliferation and apoptosis. Dev Dyn 219, 237-247.
    • (2000) Dev. Dyn. , vol.219 , pp. 237-247
    • Opperman, L.A.1    Adab, K.2    Gakunga, P.T.3
  • 62
    • 0035234660 scopus 로고    scopus 로고
    • Regulation of chondrocyte growth and differentiation by fibroblast growth factor receptor 3
    • Ornitz DM (2001) Regulation of chondrocyte growth and differentiation by fibroblast growth factor receptor 3. Novartis Found Symp 232, 63-76.
    • (2001) Novartis Found. Symp. , vol.232 , pp. 63-76
    • Ornitz, D.M.1
  • 63
    • 15844368097 scopus 로고    scopus 로고
    • Receptor specificity of the fibroblast growth factor family
    • Ornitz DM, Xu J, Colvin JS, et al. (1996) Receptor specificity of the fibroblast growth factor family. J Biol Chem 271, 15292-15297.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15292-15297
    • Ornitz, D.M.1    Xu, J.2    Colvin, J.S.3
  • 64
    • 0028147035 scopus 로고
    • The contribution of both forebrain and midbrain crest cells to the mesenchyme in the frontonasal mass of mouse embryos
    • Osumi-Yamashita N, Ninomiya Y, Doi H, Eto K (1994) The contribution of both forebrain and midbrain crest cells to the mesenchyme in the frontonasal mass of mouse embryos. Dev Biol 164, 409-419.
    • (1994) Dev. Biol. , vol.164 , pp. 409-419
    • Osumi-Yamashita, N.1    Ninomiya, Y.2    Doi, H.3    Eto, K.4
  • 66
    • 0032146074 scopus 로고    scopus 로고
    • Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryos
    • Partanen J, Schwartz L, Rossant J (1998) Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryos. Genes Dev 12, 2332-2344.
    • (1998) Genes Dev. , vol.12 , pp. 2332-2344
    • Partanen, J.1    Schwartz, L.2    Rossant, J.3
  • 67
    • 0032146074 scopus 로고    scopus 로고
    • Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryos
    • Partanen J, Schwartz L, Rossant J (1998) Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryos. Genes Dev 12, 2332-2344.
    • (1998) Genes Dev. , vol.12 , pp. 2332-2344
    • Partanen, J.1    Schwartz, L.2    Rossant, J.3
  • 68
    • 5044240692 scopus 로고    scopus 로고
    • Diverse roles of EPH receptors and ephrins in the regulation of cell migration and tissue assembly
    • Poliakov A, Cotrina M, Wilkinson DG (2004) Diverse roles of EPH receptors and ephrins in the regulation of cell migration and tissue assembly. Dev Cell 7, 465-480.
    • (2004) Dev. Cell , vol.7 , pp. 465-480
    • Poliakov, A.1    Cotrina, M.2    Wilkinson, D.G.3
  • 69
    • 0016782826 scopus 로고
    • Migration of cranial neural crest cells in a cell-free hyaluronate-rich matrix
    • Pratt RM, Larsen MA, Johnston MC (11975) Migration of cranial neural crest cells in a cell-free hyaluronate-rich matrix. Dev Biol 44, 298-305.
    • (1975) Dev. Biol. , vol.44 , pp. 298-305
    • Pratt, R.M.1    Larsen, M.A.2    Johnston, M.C.3
  • 72
    • 0034106166 scopus 로고    scopus 로고
    • Integration of FGF and TWIST in calvarial bone and suture development
    • Rice DPC, Åberg T, Chan Y-S, et al. (2000) Integration of FGF and TWIST in calvarial bone and suture development. Development 127, 1845-1855.
    • (2000) Development , vol.127 , pp. 1845-1855
    • Rice, D.P.C.1    Åberg, T.2    Chan, Y.-S.3
  • 73
    • 0032515975 scopus 로고    scopus 로고
    • Activating mutations in the extracellular domain of the fibroblast growth factor receptor 2 function by disruption of the disulphide bond in the third immunoglobulin-like domain
    • Robertson SC, Meyer AN, Hart KC, Galvin BD, Webster MK, Donoghue DJ (1998) Activating mutations in the extracellular domain of the fibroblast growth factor receptor 2 function by disruption of the disulphide bond in the third immunoglobulin-like domain. Proc Natl Acad Sci USA 95, 4567-4572.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 4567-4572
    • Robertson, S.C.1    Meyer, A.N.2    Hart, K.C.3    Galvin, B.D.4    Webster, M.K.5    Donoghue, D.J.6
  • 74
    • 0030997636 scopus 로고    scopus 로고
    • Prorhombomeric subdivision of the mammalian embryonic hindbrain: Is it functionally meaningful?
    • Ruberte E, Wood HB, Morriss-Kay GM (1997) Prorhombomeric subdivision of the mammalian embryonic hindbrain: is it functionally meaningful? Int J Dev Biol 41, 213-222.
    • (1997) Int. J. Dev. Biol. , vol.41 , pp. 213-222
    • Ruberte, E.1    Wood, H.B.2    Morriss-Kay, G.M.3
  • 75
    • 0029109137 scopus 로고
    • Identical mutations in the FGFR2 gene cause both Pfeiffer and Crouzon syndrome phenotypes
    • Rutland P, Pulleyn LJ, Reardon W, et al. (1995) Identical mutations in the FGFR2 gene cause both Pfeiffer and Crouzon syndrome phenotypes. Nat Genet 9, 173-176.
    • (1995) Nat. Genet. , vol.9 , pp. 173-176
    • Rutland, P.1    Pulleyn, L.J.2    Reardon, W.3
  • 76
    • 0142215398 scopus 로고    scopus 로고
    • Cranial neural crest and the building of the vertebrate head
    • Santagati F, Rijli FM (2003) Cranial neural crest and the building of the vertebrate head. Nat Rev Neurosci 4, 806-818.
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 806-818
    • Santagati, F.1    Rijli, F.M.2
  • 77
    • 0026487321 scopus 로고
    • Vital dye analysis of cranial neural crest cell migration in the mouse embryo
    • Serbedzija GN, Bronner-Fraser M, Fraser SE (1992) Vital dye analysis of cranial neural crest cell migration in the mouse embryo. Development 116, 297-307.
    • (1992) Development , vol.116 , pp. 297-307
    • Serbedzija, G.N.1    Bronner-Fraser, M.2    Fraser, S.E.3
  • 78
    • 0027503639 scopus 로고
    • Two FGF-receptor homologues of Drosophila: One is expressed in mesodermal primordium in early embryos
    • Shishido E, Higashijima S-I, Emory Y, Saigo K (1993) Two FGF-receptor homologues of Drosophila: one is expressed in mesodermal primordium in early embryos. Development 117, 751-761.
    • (1993) Development , vol.117 , pp. 751-761
    • Shishido, E.1    Higashijima, S.-I.2    Emory, Y.3    Saigo, K.4
  • 79
    • 0036308745 scopus 로고    scopus 로고
    • Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo
    • Soo K, O'Rourke MP, et al. (2002) Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo. Dev Biol 247, 251-270.
    • (2002) Dev. Biol. , vol.247 , pp. 251-270
    • Soo, K.1    O'Rourke, M.P.2
  • 80
    • 0022924539 scopus 로고
    • Analysis of cranial neural crest cell migration and early fates in postimplantation rat chimaeras
    • Tan S-S, Morriss-Kay GM (1986) Analysis of cranial neural crest cell migration and early fates in postimplantation rat chimaeras. J Embryol Exp Morph 98, 21-58.
    • (1986) J,. Embryol. Exp. Morph. , vol.98 , pp. 21-58
    • Tan, S.-S.1    Morriss-Kay, G.M.2
  • 81
    • 0023663425 scopus 로고
    • The twist gene: Isolation of a Drosophila zygotic gene necessary for the establishment of dorsoventral pattern
    • Thisse B, el Messal M, Perrin-Schmitt F (1987) The twist gene: isolation of a Drosophila zygotic gene necessary for the establishment of dorsoventral pattern. Nucleic Acids Res 15, 3439-3453.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 3439-3453
    • Thisse, B.1    el Messal, M.2    Perrin-Schmitt, F.3
  • 82
    • 18144381751 scopus 로고    scopus 로고
    • FGFR3 P250R mutation increases the risk of reoperation in apparent 'non-syndromic' coronal craniosynostosis
    • Thomas GPL, Wilkie AOMW, Richards PG, Wall SA (2005) FGFR3 P250R mutation increases the risk of reoperation in apparent 'non-syndromic' coronal craniosynostosis. J Craniofac Surg 16, 347-352.
    • (2005) J. Craniofac. Surg. , vol.16 , pp. 347-352
    • Thomas, G.P.L.1    Wilkie, A.O.M.W.2    Richards, P.G.3    Wall, S.A.4
  • 83
    • 0034329020 scopus 로고    scopus 로고
    • Patterning the cranial neural crest: Hindbrain segmentation and Hox gene plasticity
    • Trainor PA, Krumlauf R (2000) Patterning the cranial neural crest: hindbrain segmentation and Hox gene plasticity. Nat Rev Neurosci 1, 116-124.
    • (2000) Nat. Rev. Neurosci. , vol.1 , pp. 116-124
    • Trainor, P.A.1    Krumlauf, R.2
  • 84
    • 2942560339 scopus 로고    scopus 로고
    • Mutations of ephrin-B1 (EFNB1), a marker of tissue boundary formation, cause craniofrontonasal syndrome
    • Twigg S, Kan R, Babbs C, et al. (2004) Mutations of ephrin-B1 (EFNB1), a marker of tissue boundary formation, cause craniofrontonasal syndrome. Proc Natl Acad Sci USA 101, 8652-8657.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 8652-8657
    • Twigg, S.1    Kan, R.2    Babbs, C.3
  • 85
    • 85026136447 scopus 로고    scopus 로고
    • Regional dura mater differentially regulates osteoblast gene expression
    • Warren SM, Greenwald JA, Nacamuli RP, et al. (2003a) Regional dura mater differentially regulates osteoblast gene expression. J Craniofac Surg 14, 363-370.
    • (2003) J. Craniofac. Surg. , vol.14 , pp. 363-370
    • Warren, S.M.1    Greenwald, J.A.2    Nacamuli, R.P.3
  • 87
    • 2442661362 scopus 로고    scopus 로고
    • Mutations of the ephrin-B1 gene cause craniofrontonasal syndrome
    • Wieland I, Jacubiczka S, Muschke P, et al. (2004) Mutations of the ephrin-B1 gene cause craniofrontonasal syndrome. Am J Hum Genet 74, 1209-1215.
    • (2004) Am. J. Hum. Genet. , vol.74 , pp. 1209-1215
    • Wieland, I.1    Jacubiczka, S.2    Muschke, P.3
  • 88
    • 0028798546 scopus 로고
    • Apert syndrome results from localised mutations of FGFR2 and is allelic with Crouzon syndrome
    • Wilkie AOM, Slaney SF, Oldridge M, et al. (1995) Apert syndrome results from localised mutations of FGFR2 and is allelic with Crouzon syndrome. Nat Genet 9, 165-172.
    • (1995) Nat. Genet. , vol.9 , pp. 165-172
    • Wilkie, A.O.M.1    Slaney, S.F.2    Oldridge, M.3
  • 89
    • 0030769180 scopus 로고    scopus 로고
    • Craniosynostosis: Genes and mechanisms
    • Wilkie AOM (1997) Craniosynostosis: genes and mechanisms. Hum Mol Genet 6, 1647-1656.
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 1647-1656
    • Wilkie, A.O.M.1
  • 90
    • 17844402791 scopus 로고    scopus 로고
    • Bad bones, absent smell, selfish testes: The pleiotropic consequences of human FGF receptor mutations
    • Wilkie AOM (2005) Bad bones, absent smell, selfish testes: the pleiotropic consequences of human FGF receptor mutations. Cytokine Growth Factor Rev 16, 187-203.
    • (2005) Cytokine Growth Factor Rev. , vol.16 , pp. 187-203
    • Wilkie, A.O.M.1
  • 91
    • 0035287473 scopus 로고    scopus 로고
    • Multiple roles of EPH receptors and ephrins in neural development
    • Wilkinson DG (2001) Multiple roles of EPH receptors and ephrins in neural development. Nat Rev Neurosci 2, 155-164.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 155-164
    • Wilkinson, D.G.1
  • 93
    • 0034687699 scopus 로고    scopus 로고
    • Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome
    • Yu K, Herr AB, Waksman G, Ornitz DM (2000) Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome. Proc Natl Acad Sci USA 97, 14536-14541.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 14536-14541
    • Yu, K.1    Herr, A.B.2    Waksman, G.3    Ornitz, D.M.4
  • 94
    • 0038782306 scopus 로고    scopus 로고
    • Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth
    • Yu K, Xu J, Liu Z, et al. (2003) Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development 130, 3063-3074.
    • (2003) Development , vol.130 , pp. 3063-3074
    • Yu, K.1    Xu, J.2    Liu, Z.3
  • 95
    • 0028582035 scopus 로고
    • Fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation
    • Yamagouchi TP, Harpal K, Henkemeyer M, Rossant J (1994) Fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev 8, 3032-3044.
    • (1994) Genes Dev. , vol.8 , pp. 3032-3044
    • Yamagouchi, T.P.1    Harpal, K.2    Henkemeyer, M.3    Rossant, J.4
  • 96
    • 0034641606 scopus 로고    scopus 로고
    • A Pro250Arg substitution in mouse Fgfr1 causes increased expression of Cbfa1 and premature fusion of calvarial sutures
    • Zhou YX, Xu X, Chen L, Li C, Brodie SG, Deng CX (2000) A Pro250Arg substitution in mouse Fgfr1 causes increased expression of Cbfa1 and premature fusion of calvarial sutures. Hum Mol Genet 9, 2001-2008.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 2001-2008
    • Zhou, Y.X.1    Xu, X.2    Chen, L.3    Li, C.4    Brodie, S.G.5    Deng, C.X.6


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