Inorganic phosphate induces mammalian growth plate chondrocyte apoptosis in a mitochondrial pathway involving nitric oxide and JNK MAP kinase

Calcified Tissue International

Volumn 88, Issue 2, 2011, Pages 96-108

  Zhong, M ^a   Carney, D H ^b   Jo, H ^c   Boyan, B D ^a   Schwartz, Z ^a  

^a Emory University   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c University Medical School   (United States)

Author keywords

Apoptosis; Endochondral ossification; Growth plate chondrocyte; JNK MAP kinase; Nitric oxide; Phosphate

Indexed keywords

CASPASE 3; CYTOCHROME C; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHATE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARTILAGE CELL; CELL COUNT; CELL VIABILITY; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; FEMALE; GROWTH PLATE; MALE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; APOPTOSIS; CASPASE 3; CHONDROCYTES; GROWTH PLATE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; NITRIC OXIDE; PHOSPHATES; RATS; SIGNAL TRANSDUCTION;

EID: 79954434097     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-010-9433-5     Document Type: Article

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